Chung-I Chang

发表

Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors.

Ching-Chow Chen, J. Guh, Wei-Jan Huang, 2011, European journal of medicinal chemistry.

Pravastatin attenuates carboplatin-induced cardiotoxicity via inhibition of oxidative stress associated apoptosis

T. Chiu, Chung-I Chang, Ching-Feng Cheng, 2008, Apoptosis.

Synthesis and Biological Evaluation of ortho‐Aryl N‐Hydroxycinnamides as Potent Histone Deacetylase (HDAC) 8 Isoform‐Selective Inhibitors

Yi-Ching Wang, W. Hou, Tai-Lin Lee, 2012, ChemMedChem.

Structural Basis for the Peptidoglycan-Editing Activity of YfiH

C. Kuo, Chung-I Chang, Meng-Sheng Lee, 2022, mBio.

Structural basis for the peptidoglycan editing activity of YfiH

C. Kuo, Chung-I Chang, Meng-Sheng Lee, 2021, bioRxiv.

Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc

S. Tzeng, M. Ho, D. Mengin-Lecreulx, 2017, Nature Communications.

Structural basis for conserved complement factor-like function in the antimalarial protein TEP1

J. Deisenhofer, E. Levashina, Richard H. G. Baxter, 2007, Proceedings of the National Academy of Sciences.

Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene Kinase Pim-1.

Wei-Jan Huang, Shi-Wei Chao, Chung-I Chang, 2015, Journal of natural products.

1H, 13C and 15N resonance assignments of the pyrin domain from human PYNOD

Chung-I Chang, Chi-Fon Chang, M. Su, 2012, Biomolecular NMR Assignments.

Data publication with the structural biology data grid supports live analysis

Oleg V. Tsodikov, Stephen C. Blacklow, Amedeo Caflisch, 2016, Nature Communications.

Expression, purification, refolding, and characterization of recombinant human soluble-Fas ligand from

Chung-I Chang, Chang-Youh Tsai, Shye-Jye Tang, 2005 .

Structure of Tracheal Cytotoxin in Complex with a Heterodimeric Pattern-Recognition Receptor

J. Deisenhofer, D. Borek, D. Mengin-Lecreulx, 2006, Science.

Structure of yeast Ape1 and its role in autophagic vesicle formation

Guang-Chao Chen, M. Ho, Yuan-Chih Chang, 2015, Autophagy.

HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation.

Q. Cai, G. Marcucci, Jing Qi, 2015, Cell stem cell.

Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition.

J. Deisenhofer, K. Ihara, D. Mengin-Lecreulx, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis of N‐Hydroxycinnamides Capped with a Naturally Occurring Moiety as Inhibitors of Histone Deacetylase

F. Hsu, Wei-Jan Huang, Shi-Wei Chao, 2010, ChemMedChem.

Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases

M. Ho, Chung-I Chang, Lu-Chu Ke, 2019, mBio.

A Drosophila Pattern Recognition Receptor Contains a Peptidoglycan Docking Groove and Unusual L,D-Carboxypeptidase Activity

J. Deisenhofer, B. Lemaître, M. Hervé, 2004, PLoS biology.

Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.

Radha Akella, E. Goldsmith, M. Cobb, 2002, Molecular cell.

Structure of MAPKs.

E. Goldsmith, M. Cobb, Chung-I Chang, 2004, Methods in molecular biology.

Another twist in helix C and a missing pocket.

E. Goldsmith, Chung-I Chang, 2002, Structure.

A Lon-Like Protease with No ATP-Powered Unfolding Activity

Wan-Ling Wu, J. Liao, Shih-Hsiung Wu, 2012, PloS one.

Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface*

Shao‐Chen Lee, Wen‐guey Wu, Chung-I Chang, 2014, The Journal of Biological Chemistry.

Structural Basis for the Magnesium-Dependent Activation and Hexamerization of the Lon AAA+ Protease.

C. Lim, J. Liao, Shih-Hsiung Wu, 2016, Structure.

The N-terminal substrate-recognition domain of a LonC protease exhibits structural and functional similarity to cytosolic chaperones.

Hongchun Li, Lee-Wei Yang, J. Liao, 2013, Acta crystallographica. Section D, Biological crystallography.

Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease

G. Pintilie, Kaiming Zhang, Shanshan Li, 2020, bioRxiv.

Structural Insights into the Allosteric Operation of the Lon AAA+ Protease.

Shih-Hsiung Wu, Chung-I Chang, S. Su, 2016, Structure.

Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex

Kaiming Zhang, Shanshan Li, C. Kuo, 2021, Science advances.

Complete three-dimensional structures of the Lon protease translocating a protein substrate

G. Pintilie, Kaiming Zhang, Shanshan Li, 2021, Science advances.

Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc

S. Tzeng, M. Ho, D. Mengin-Lecreulx, 2017, Nature Communications.

1H, 13C and 15N resonance assignments of the pyrin domain from human PYNOD

Chung-I Chang, M. Su, Chi-Fon Chang, 2012, Biomolecular NMR Assignments.

Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue

C. Kuo, Chung-I Chang, Mingmei Su, 2013, PloS one.

Molecular insights into substrate recognition and discrimination by the N-terminal domain of Lon AAA+ protease

S. Tzeng, Shing‐Jong Huang, Chung-I Chang, 2020, bioRxiv.

Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors.

J. Guh, Wei-Jan Huang, Chia-Chun Yu, 2011, European journal of medicinal chemistry.