E. Kantharaj

发表

Discovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile.

Kay Lin Goh, Z. Bonday, J. Wood, 2011, Journal of medicinal chemistry.

Isoniazid Pharmacokinetics-Pharmacodynamics in an Aerosol Infection Model of Tuberculosis

E. Kantharaj, V. Nandi, S. Bharath, 2004, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics-Pharmacodynamics of Rifampin in an Aerosol Infection Model of Tuberculosis

E. Kantharaj, V. Nandi, S. Gaonkar, 2003, Antimicrobial Agents and Chemotherapy.

Simultaneous measurement of drug metabolic stability and identification of metabolites using ion-trap mass spectrometry.

E. Kantharaj, R. Gilissen, A. Tuytelaars, 2003, Rapid communications in mass spectrometry : RCM.

Simultaneous measurement of metabolic stability and metabolite identification of 7-methoxymethylthiazolo[3,2-a]pyrimidin-5-one derivatives in human liver microsomes using liquid chromatography/ion-trap mass spectrometry.

E. Kantharaj, C. Mackie, R. Gilissen, 2005, Rapid communications in mass spectrometry : RCM.

Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies.

Xiaofeng Wu, P. Yeo, E. Kantharaj, 2007, Biomedical chromatography : BMC.

In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species.

K. Sangthongpitag, P. Yeo, E. Kantharaj, 2007, Biological & pharmaceutical bulletin.

Synthesis of 2-substituted benzoxazoles and benzimidazoles based on mass spectral ortho interactions

D. V. Ramana, E. Kantharaj, D. Ramana, 1995 .

Mass spectrometer as a probe in the synthesis of 2-substituted benzimidazoles

E. Kantharaj, D. Ramana, 1994 .

Dualortho interaction in 2-substituted-3-(2-methylphenyl)-4(3H)-quinazolinones and their thio analogues under electron impact conditions

D. V. Ramana, E. Kantharaj, D. Ramana, 1995 .

FACILE SYNTHESIS OF 2-ARYL-4H-3,1-BENZOXAZIN-4-ONES

E. Kantharaj, D. Ramana, 1993 .

Cycloreversal reaction and ortho interactions in 2‐aryl‐4H‐3, 1‐benzoxazin‐4‐ones on electron impact

D. V. Ramana, E. Kantharaj, D. Ramana, 1995 .

Histone Deacetylase Inhibitors as Therapeutic Agents for Cancer Therapy: Drug Metabolism and Pharmacokinetic Properties

E. Kantharaj, R. Jayaraman, 2011 .

Discovery of Kinase Spectrum Selective Macrocycle

J. Wood, A. Poulsen, Meredith Williams, 2011 .

SB1518: A Potent and Orally Active JAK2 Inhibitor for the Treatment of Myeloproliferative Disorders.

Z. Bonday, J. Wood, J. Griffin, 2007 .

The use of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry to explore the in vitro metabolism of cyanoalkyl piperidine derivatives.

E. Kantharaj, C. Mackie, R. Gilissen, 2005, Biomedical chromatography : BMC.