C. Chen

发表

Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.

F. Lombardo, P. Atadja, S. Whitebread, 2011, Journal of medicinal chemistry.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

Fluorous Synthesis of Hydantoin-, Piperazinedione-, and Benzodiazepinedione-Fused Tricyclic and Tetracyclic Ring Systems.

Wei Zhang, S. Geib, D. Curran, 2006, European journal of organic chemistry.

A highly efficient microwave-assisted suzuki coupling reaction of aryl perfluorooctylsulfonates with boronic acids.

Wei Zhang, C. Chen, Yimin Lu, 2004, Organic letters.

Relative reactivities of polynuclear aromatic systems. V. Kinetics, isomer distribution, and additivity in the bromination of the dimethylnaphthalenes

E. Berliner, C. Chen, Jean B. Kim, 1970 .

"Addition" and "Subtraction": Selectivity Design for Type II Maternal Embryonic Leucine Zipper Kinase Inhibitors.

W. Shao, J. Duca, K. Hurov, 2017, Journal of medicinal chemistry.

Solution-phase preparation of a 560-compound library of individual pure mappicine analogues by fluorous mixture synthesis.

Wei Zhang, D. Curran, C. Chen, 2002, Journal of the American Chemical Society.

Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824).

P. Atadja, E. Francotte, W. Shao, 2010, Journal of medicinal chemistry.

FluoMar, a fluorous version of the Marshall resin for solution-phase library synthesis.

C. Chen, Wei Zhang, 2003, Organic letters.

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.

Sarah L. Williams, W. Sellers, Z. Deng, 2020, Journal of medicinal chemistry.

4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.

Rajiv Chopra, Sunkyu Kim, Ming Xu, 2010, Journal of medicinal chemistry.

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ping Zhu, Gang Liu, Peter Fekkes, 2016, Nature.

A traceless perfluorooctylsulfonyl tag for deoxygenation of phenols under microwave irradiation

Wei Zhang, C. Chen, Yimin Lu, 2004 .

A highly efficient microwave-assisted suzuki coupling reaction of aryl perfluorooctylsulfonates with boronic acids.

Wei Zhang, C. Chen, Yimin Lu, 2004, Organic letters.

Fluorous synthesis of biaryl-substituted proline analogs by 1,3-dipolar cycloaddition and Suzuki coupling reactions

C. Chen, Wei Zhang, 2005 .

Fluorous reagents and scavengers versus solid-supported reagents and scavengers, a reaction rate and kinetic comparison

C. Chen, Wei Zhang, 2005, Molecular Diversity.

A Traceless Perfluorooctylsulfonyl Tag for Deoxygenation of Phenols under Microwave Irradiation.

C. Chen, Wei Zhang, Yimin Lu, 2004 .

Use of fluorous silica gel to separate fluorous thiol quenching derivatives in solution-phase parallel synthesis

Wei Zhang, D. Curran, C. Chen, 2002 .

Fluorous electrophilic scavengers for solution-phase parallel synthesis

Wei Zhang, C. Chen, T. Nagashima, 2003 .

Transfer of Chirality in Radical Cyclizations. Cyclization of o-Haloacrylanilides to Oxindoles with Transfer of Axial Chirality to a Newly Formed Stereocenter

D. Curran, C. Chen, A. Liu, 1999 .

Asymmetric radical cyclization reactions of axially chiral N -allyl- o -iodoanilides to form enantioenriched N -acyl dihydroindoles

D. Curran, C. Chen, Steven J. Geib, 2004 .

Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors.

Paul N. Mortenson, M. Congreve, R. Cheng, 2012, ACS medicinal chemistry letters.

Determination of the absolute configuration of 1,3,5,7-tetramethyl-1,3-dihydroindol-2-one by optical rotation computation

P. Wipf, D. Beratan, R. Kondru, 1999 .

Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitor.

D. Chin, B. Lagu, B. Firestone, 2013, Journal of medicinal chemistry.

The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.

P. Atadja, L. Urban, Nicole Davis, 2011, Bioorganic & medicinal chemistry letters.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.

P. Atadja, L. Urban, Nicole Davis, 2011, Bioorganic & medicinal chemistry letters.

Chemo- and regioselective halogenation of 4-(pyrazol-4-yl)-pyrimidines

C. Chen, Y. Cho, M. Sung, 2009 .