L. Perez

发表

Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.

F. Lombardo, P. Atadja, S. Whitebread, 2011, Journal of medicinal chemistry.

Second-Site NMR Screening with a Spin-Labeled First Ligand

Wolfgang Jahnke, C. Gregory Paris, W. Jahnke, 2000 .

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

Dual Allosteric Inhibition of SHP2 Phosphatase.

Sarah L. Williams, S. Blacklow, M. Glick, 2018, ACS chemical biology.

Synthesis and enzymatic studies of bisubstrate analogues for farnesyl diphosphate synthase.

M. Jacobson, C. Poulter, L. Perez, 2015, The Journal of organic chemistry.

N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).

P. Atadja, P. Lassota, K. Bair, 2003, Journal of medicinal chemistry.

1-amino-4-benzylphthalazines as orally bioavailable smoothened antagonists with antitumor activity.

J. Williams, S. Peukert, R. Guo, 2009, Journal of medicinal chemistry.

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.

Sarah L. Williams, W. Sellers, Z. Deng, 2020, Journal of medicinal chemistry.

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ping Zhu, Gang Liu, Peter Fekkes, 2016, Nature.

The Synthesis of a Novel Inhibitor of B-Raf Kinase

T. Ramsey, L. Perez, D. Batt, 2006 .

Second-site NMR screening and linker design.

Wolfgang Jahnke, Marcel J J Blommers, Jutta Heim, 2003, Current topics in medicinal chemistry.

Discovery and Development of Farydak (NVP-LBH589, Panobinostat) as an Anticancer Drug

P. Atadja, L. Perez, 2016 .

The role of the acidity of N-heteroaryl sulfonamides as inhibitors of bcl-2 family protein-protein interactions.

Clayton Springer, Xiaoling Xie, Walter Michael, 2013, ACS medicinal chemistry letters.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.