N. Nam

发表

New benzothiazole/thiazole-containing hydroxamic acids as potent histone deacetylase inhibitors and antitumor agents.

J. Hong, B. Han, S. H. Park, 2013, Medicinal chemistry (Shariqah (United Arab Emirates)).

Novel Isatin-Based Hydroxamic Acids as Histone Deacetylase Inhibitors and Antitumor Agents.

N. Nam, 2014 .

Conformationally constrained peptide analogues of pTyr-Glu-Glu-Ile as inhibitors of the Src SH2 domain binding.

K. Parang, N. Nam, Guofeng Ye, 2004, Journal of medicinal chemistry.

Design, synthesis and evaluation of novel 2-oxoindoline-based acetohydrazides as antitumor agents

S. Han, T. Tung, N. Nam, 2022, Scientific Reports.

Design, synthesis, and evaluation of novel (E)‐N'‐(3‐allyl‐2‐hydroxy)benzylidene‐2‐(4‐oxoquinazolin‐3(4H)‐yl)acetohydrazides as antitumor agents

S. Han, T. Tung, P. Dung, 2021, Archiv der Pharmazie.

New Acetohydrazides Incorporating 2‐Oxoindoline and 4‐Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity

S. Han, N. Nam, Hye Jin Lee, 2020, Chemistry & biodiversity.

Design, synthesis, and evaluation of novel N'-substituted-1-(4-chlorobenzyl)-1H-indol-3-carbohydrazides as antitumor agents

Lai Duc Anh, S. Han, T. Tung, 2020, Journal of enzyme inhibition and medicinal chemistry.

(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

S. Han, N. Nam, H. Pham-The, 2019, Journal of enzyme inhibition and medicinal chemistry.

Determination of the substrate-docking site of protein tyrosine kinase C-terminal Src kinase

Keykavous Parang, K. Parang, Xiaofeng Lin, 2003, Proceedings of the National Academy of Sciences of the United States of America.

In Silico Assessment of ADME Properties: Advances in Caco-2 Cell Monolayer Permeability Modeling.

G. Casañola-Martín, H. Le-Thi-Thu, N. Nam, 2019, Current topics in medicinal chemistry.

Conformationally constrained peptide analogues of pTyr-Glu-Glu-Ile as inhibitors of the Src SH2 domain binding.

K. Parang, N. Nam, Guofeng Ye, 2004 .

Naturally occurring NF-kappaB inhibitors.

N. Nam, 2006, Mini reviews in medicinal chemistry.

Synthesis and cytotoxic activity of A-ring modified betulinic acid derivatives.

N. Nam, B. Ahn, Y. Kim, 2003, Bioorganic & medicinal chemistry letters.

Current targets for anticancer drug discovery.

K. Parang, N. Nam, 2003, Current drug targets.

Design and Synthesis of Sustain-Acting Melatonin Prodrugs

N. Nam, Phạm Văn Thoại, 2013 .

Design, Synthesis and Bioevaluation of Two Series of 3‐[(1‐Benzyl‐1H‐1,2,3‐triazol‐4‐yl)methyl]quinazolin‐4(3H)‐ones and N‐(1‐Benzylpiperidin‐4‐yl)quinazolin‐4‐amines

S. Han, N. Nam, H. Pham-The, 2020, Chemistry & biodiversity.

Design, Synthesis and Evaluation of Novel Indirubin-based N-Hydroxybenzamides, N-Hydroxypropenamides and N-Hydroxyheptanamides as Histone Deacetylase Inhibitors and Antitumor Agents.

S. Han, T. Tung, P. Dung, 2020, Bioorganic & medicinal chemistry letters.

Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.

S. Han, V. Hue, N. Nam, 2020, Bioorganic chemistry.

Quinazolin‐4(3H)‐one‐Based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

S. Han, N. Nam, L. Huong, 2019, Chemistry & biodiversity.

Quinazoline‐Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

S. Han, P. Dung, N. Nam, 2018, Chemistry & biodiversity.

Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents.

S. Han, P. Dung, N. Nam, 2018, Bioorganic chemistry.

Novel N-hydroxybenzamides incorporating 2-oxoindoline with unexpected potent histone deacetylase inhibitory effects and antitumor cytotoxicity.

S. Han, N. Nam, Jisung Kim, 2017, Bioorganic chemistry.

Novel 2-oxoindoline-based hydroxamic acids: synthesis, cytotoxicity, and inhibition of histone deacetylation

B. Han, S. Han, P. Dung, 2015 .

Benzothiazole-containing hydroxamic acids as histone deacetylase inhibitors and antitumor agents.

J. Hong, B. Han, S. H. Park, 2011, Bioorganic & medicinal chemistry letters.

Preliminary structure-antiangiogenic activity relationships of 4-senecioyloxymethyl-6,7-dimethoxycoumarin.

N. Nam, D. Hong, B. Ahn, 2002, Bioorganic & medicinal chemistry letters.

Cytotoxic 2',5'-dihydroxychalcones with unexpected antiangiogenic activity.

N. Nam, D. Hong, B. Ahn, 2003, European journal of medicinal chemistry.

Mechanisms of inactivation of lipoxygenases by phenidone and BW755C.

D. Mansuy, N. Nam, J. Battioni, 1991, Biochemistry.

Synthesis and cytotoxicity of 2,5-dihydroxychalcones and related compounds

N. Nam, Seong-Cheol Bang, D. Hong, 2004, Archives of pharmacal research.

Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.

B. Han, S. H. Park, S. Han, 2013, European journal of medicinal chemistry.

Reactions of solid-supported reagents and solid supports with alcohols and phenols through their hydroxyl functional group.

K. Parang, N. Nam, S. Sardari, 2003, Journal of combinatorial chemistry.

Synthesis and biological evaluation of a series of 2-(substitutedphenyl)benzothiazoles.

P. Thuong, P. Dung, N. Nam, 2011, Medicinal chemistry (Shariqah (United Arab Emirates)).

Antiangiogenic activity of lupeol from Bombax ceiba

K. Bae, N. Nam, B. Ahn, 2003, Phytotherapy research : PTR.

Xanthine oxidase inhibitors from Archidendron clypearia (Jack.) I.C. Nielsen: Results from systematic screening of Vietnamese medicinal plants.

N. Duong, T. Bach, Le Nguyen Thanh, 2017, Asian Pacific journal of tropical medicine.

Design, synthesis and biological evaluation of novel hydroxamic acids bearing artemisinin skeleton.

B. Han, N. Nam, V. D. Tien, 2016, Bioorganic chemistry.

Syntheses of certain 3-aryl-2-propenoates and evaluation of their cytotoxicity.

N. Nam, Y. Kim, D. Hong, 2001, Bioorganic & medicinal chemistry letters.

Carboxylic acid and phosphate ester derivatives of fluconazole: synthesis and antifungal activities.

K. Parang, N. Nam, S. Sardari, 2004, Bioorganic & medicinal chemistry.

Esters of chlorambucil with 2-substituted 1,4-dihydroxy-9,10-anthraquinones as multifunctional anticancer agents.

G. Jin, N. Nam, Y. Kim, 2001, European journal of medicinal chemistry.

Cytotoxic activity of Vietnamese herbal medicines against A549 cells

K. Bae, N. Cuong, N. Nam, 2002 .

Synthesis and Evaluation of the Antitumor Activity of 2‐Substituted 1,4‐Dihydroxy‐9,10‐anthraquinones

N. Nam, G. Song, B. Ahn, 2000, Archiv der Pharmazie.

Synthesis and anti-tumor activity of novel combretastatins: combretocyclopentenones and related analogues.

N. Nam, D. Hong, B. Ahn, 2002, Bioorganic & medicinal chemistry letters.

Synthesis and cytotoxicity of 3,4-diaryl-2(5H)-furanones.

N. Nam, B. Ahn, Y. Kim, 2002, Bioorganic & medicinal chemistry letters.

Combretoxazolones: synthesis, cytotoxicity and antitumor activity.

N. Nam, Y. Kim, D. Hong, 2001, Bioorganic & medicinal chemistry letters.

Combretastatin A-4 analogues as antimitotic antitumor agents.

N. Nam, 2003, Current medicinal chemistry.

Water soluble prodrugs of the antitumor agent 3-[(3-amino-4-methoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)cyclopent-2-ene-1-one.

N. Nam, D. Hong, B. Ahn, 2003, Bioorganic & medicinal chemistry.

Synthesis and Antitumor Activity of Novel Combretastatins: Combretocyclopentenones and Related Analogues.

N. Nam, B. Ahn, Hwan‐Mook Kim, 2002 .

Synthesis, cytotoxicity and antitumor activity of 2,3-Diarylcy-clopent-2-ene-1-ones

N. Nam, D. Hong, Hwan‐Mook Kim, 2002, Archives of pharmacal research.

Synthesis and cytotoxicity of some rigid derivatives of methyl 2,5-Dihydroxycinnamate

N. Nam, D. Hong, Hwan‐Mook Kim, 2002, Archives of pharmacal research.

Inhibitory effects of Vietnamese medicinal plants on tube‐like formation of human umbilical venous cells

K. Bae, N. Nam, B. Ahn, 2003, Phytotherapy research : PTR.

Antitumor activity of unsaturated fatty acid esters of 4'-demethyldeoxypodophyllotoxin.

N. Nam, B. Ahn, Y. Kim, 2003, Bioorganic & medicinal chemistry letters.

Novel hydroxamic acids incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)-3-hydroxyimino-indolin-2-ones: synthesis, biological evaluation, and SAR analysis

S. Han, V. Hue, N. Nam, 2018, Journal of Chemical Sciences.

Exploration of some indole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

P. Huong, S. Han, P. Dung, 2017, Chemical Papers.

Prodrugs of 4'-demethyl-4-deoxypodophyllotoxin: synthesis and evaluation of the antitumor activity.

N. Nam, B. Ahn, Y. Kim, 2002, Bioorganic & medicinal chemistry letters.

ATP-phosphopeptide conjugates as inhibitors of Src tyrosine kinases.

K. Parang, N. Nam, Guofeng Ye, 2004, Bioorganic & medicinal chemistry.

Metabolic activation of acetylenes. Covalent binding of [1,2-14C]octyne to protein, DNA and haem in vitro and the protective effects of certain thiol compounds.

I. White, P. Farmer, N. Nam, 1984, The Biochemical journal.

Design, Synthesis and Biological Evaluation of Novel N-hydroxyheptanamides Incorporating 6-hydroxy-2-methylquinazolin-4(3H)-ones as Histone Deacetylase Inhibitors and Cytotoxic Agents.

N. Minh, H. Le-Thi-Thu, N. Nam, 2019, Anti-cancer agents in medicinal chemistry.

Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation

S. Han, T. Tung, N. Nam, 2021, ACS omega.

Design, Synthesis and Evaluation of Novel 3/4-((Substituted benzamidophenoxy)methyl)-N-hydroxybenzamides / propenamides as Histone Deacetylase Inhibitors and Antitumor Agents.

B. Han, S. Han, V. Hue, 2018, Anti-cancer agents in medicinal chemistry.

Hexanal phenylhydrazone is a mechanism-based inactivator of soybean lipoxygenase 1.

F. Lederer, D. Mansuy, S. Bombard, 1988, Biochemistry.

Functional Diversity of Csk, Chk, and Src SH2 Domains due to a Single Residue Variation*

Keykavous Parang, K. Parang, N. Nam, 2005, Journal of Biological Chemistry.

Synthesis and Biological Evaluation of New (−)-Gossypol-Derived Schiff Bases and Hydrazones

N. Nam, Trinh Thi Hong Nhung, V. D. Tien, 2017 .

Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.

S. Han, N. Nam, Hye Jin Lee, 2019, Bioorganic chemistry.

Design of tetrapeptide ligands as inhibitors of the Src SH2 domain.

K. Parang, N. Nam, R. Pitts, 2004, Bioorganic & medicinal chemistry.

2-Aryl- and 2-amido-benzothiazoles as multifunctional vasodilators on rat artery preparations.

F. Fusi, N. Cuong, P. Dung, 2013, European journal of pharmacology.

Alkyl and carboxylalkyl esters of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxic, and antitumor activity.

N. Nam, Seong-Cheol Bang, B. Ahn, 2004, European journal of medicinal chemistry.

Synthesis and bioevaluation of new 5-benzylidenethiazolidine-2,4-diones bearing benzenesulfonamide moiety

B. Han, S. Han, P. Dung, 2015, Medicinal Chemistry Research.

5-aryl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents: synthesis, bioevaluation and docking study.

B. Han, S. Han, Youngsoo Kim, 2015, Medicinal chemistry (Shariqah (United Arab Emirates)).

Antiinvasive, antiangiogenic and antitumour activity of Ephedra sinica extract

K. Bae, C. Lee, N. Nam, 2003, Phytotherapy research : PTR.

Solid-phase binding assays of peptides using EGFP-Src SH2 domain fusion protein and biotinylated Src SH2 domain.

K. Parang, N. Nam, Guofeng Ye, 2005, Bioorganic & medicinal chemistry letters.

Furo-1,2-naphthoquinones from Crataegus pinnatifida with ICAM-1 expression inhibition activity.

Jung-hee Kim, K. Bae, S. Kang, 2004, Planta Medica.

Inhibitory effect of Adonis amurensis components on tube‐like formation of human umbilical venous cells

N. Nam, B. Ahn, Y. Kim, 2003, Phytotherapy Research.

Synthesis and evaluation of tripodal peptide analogues for cellular delivery of phosphopeptides.

K. Parang, Xiaofeng Lin, M. Amiji, 2007, Journal of medicinal chemistry.

Effect of the aryl substituent on antitumor activity of 2-substituted-1,4-dihydroxy-9,10-anthraquinones and 2-substitutedanthracene-1,4,9,10-tetraones

G. Jin, N. Nam, B. Ahn, 1999, Archives of pharmacal research.

Development of Activity Rules and Chemical Fragment Design for In Silico Discovery of AChE and BACE1 Dual Inhibitors against Alzheimer’s Disease

G. Casañola-Martín, N. Nam, H. Pham-The, 2023, Molecules.

Design, synthesis, and bioevaluation of novel oxoindolin-2-one derivatives incorporating 1-benzyl-1H-1,2,3-triazole

S. Han, N. Nam, L. Huong, 2019, Medicinal Chemistry Research.

Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

B. Han, S. Han, Youngsoo Kim, 2014, Journal of enzyme inhibition and medicinal chemistry.

Antioxidant Activities of Vietnamese Medicinal Plants

P. Thuong, D. Sok, N. Nam, 2006 .

Synthesis and bioevaluation of new 5-benzylidenethiazolidine-2,4-diones bearing benzenesulfonamide moiety

S. Han, Youngsoo Kim, P. Dung, 2015, Medicinal Chemistry Research.

Cytotoxic 2′,5′-Dihydroxychalcones with Unexpected Antiangiogenic Activity.

N. Nam, D. Hong, B. Ahn, 2003 .

New constituents from Crinum latifolium with inhibitory effects against tube-like formation of human umbilical venous endothelial cells

Yong Kim, N. Nam, Hwan-Mook Kim, 2004, Natural product research.

NF-κB Inhibitory Activities of the Methanol Extracts and some Constituents therein of some Vietnamese Medicinal Plants

N. Nam, Y. Y. Jae, 2009 .

Exploration of novel 5′(7′)-substituted-2′-oxospiro[1,3]dioxolane-2,3′-indoline-based N-hydroxypropenamides as histone deacetylase inhibitors and antitumor agents

B. Han, S. Han, P. Dung, 2017 .

2,3-Dibenzylbutyrolactones and 1,2,3,4-tetrahydro-2-naphthoic acid γnes: structure and activity relationship in cytotoxic activity

N. Nam, B. Ahn, Y. Kim, 2002 .

Design, synthesis, and bioevaluation of novel oxoindolin-2-one derivatives incorporating 1-benzyl-1H-1,2,3-triazole

S. Han, N. Nam, L. Huong, 2019, Medicinal Chemistry Research.

Novel 2‐Oxoindoline‐Based Hydroxamic Acids: Synthesis, Cytotoxicity, and Inhibition of Histone Deacetylation.

N. Nam, 2016 .