Tien L. Huang

发表

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

Madhusoodanan Mottamal, Shilong Zheng, Tien L. Huang, 2015, Molecules.

Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents.

Tien L. Huang, R. Brun, N. Yarlett, 2011, Bioorganic & medicinal chemistry.

Novel bisbenzimidazoles with antileishmanial effectiveness.

B. Tekwani, M. Cushion, Tien L. Huang, 2008, Bioorganic & medicinal chemistry letters.

Anti‐plasmodial and anti‐leishmanial activity of conformationally restricted pentamidine congeners

B. Tekwani, Shabana I. Khan, Tien L. Huang, 2006, The Journal of pharmacy and pharmacology.

In Vitro Selection and In Vivo Efficacy of Piperazine- and Alkanediamide-Linked Bisbenzamidines against Pneumocystis Pneumonia in Mice

M. Cushion, P. Walzer, Tien L. Huang, 2006, Antimicrobial Agents and Chemotherapy.

Potential of bisbenzimidazole‐analogs toward metronidazole‐resistant Trichomonas vaginalis isolates

Travis Korosh, Tien L. Huang, N. Yarlett, 2017, Chemical biology & drug design.

Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents

Madhusoodanan Mottamal, Tien L. Huang, R. Brun, 2016, Pharmaceuticals.

Design and Synthesis of N1,N5-bis[4-(5-Alkyl-1,2,4-oxadiazol-3-yl)phenyl]glutaramides as Potential Antifungal Prodrugs

Tien L. Huang, Guangdi Wang, J. Vanden Eynde, 2013, Molecules.

Bisbenzamidines as Antifungal Agents. Are Both Amidine Functions Required to Observe an Anti-Pneumocystis carinii Activity?

M. Pottier, E. Dei‐Cas, Tien L. Huang, 2009, Molecules.

Synthesis and SAR of alkanediamide-linked bisbenzamidines with anti-trypanosomal and anti-pneumocystis activity.

M. Cushion, Tien L. Huang, N. Yarlett, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and anti-Pneumocystis carinii activity of conformationally restricted analogues of pentamidine

Tien L. Huang, I. Donkor, S. Queener, 1999 .

Synthesis, antituberculosis activity, and DNA binding affinity of a highly diverse library of 1,4-diarylpiperazines

Tien L. Huang, J. V. Eynde, Louis LeCour, 2003 .

Trypanocidal activity of conformationally restricted pentamidine congeners.

Tien L. Huang, D. Rattendi, C. Bacchi, 2003, Journal of medicinal chemistry.

Novel bisbenzamidines as potential drug candidates for the treatment of Pneumocystis carinii pneumonia.

M. Cushion, P. Walzer, Tien L. Huang, 2004, Bioorganic & medicinal chemistry letters.

Highly Active Anti-Pneumocystis carinii Compounds in a Library of Novel Piperazine-Linked Bisbenzamidines and Related Compounds

M. Cushion, P. Walzer, Tien L. Huang, 2004, Antimicrobial Agents and Chemotherapy.

Parallel solution-phase synthesis of conformationally restricted congeners of pentamidine and evaluation of their antiplasmodial activities.

M. Cushion, D. Krogstad, Tien L. Huang, 2004, Journal of medicinal chemistry.

Original Article Novel piperazine induces apoptosis in U937 cells

Tien L. Huang, I. Donkor, S. Adunyah, 2011 .

Novel piperazine induces apoptosis in U937 cells.

Tien L. Huang, I. Donkor, S. Adunyah, 2011, International journal of biochemistry and molecular biology.

Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.

Jiawang Liu, Yanyuan Wu, Shilong Zheng, 2015, Future medicinal chemistry.

Evaluation of bisbenzamidines as inhibitors for matriptase-2.

J. Bajorath, Erik Gilberg, M. Gütschow, 2016, Bioorganic & medicinal chemistry letters.

Fragment-based design of symmetrical bis-benzimidazoles as selective inhibitors of the trimethoprim-resistant, type II R67 dihydrofolate reductase.

J. Pelletier, J. Toulouse, D. Forge, 2012, Journal of medicinal chemistry.

P. Walzer, Tien L. Huang, M. Collins, 2014 .

Piperazine-linked bisbenzamidines: a novel class of antileishmanial agents.

B. Tekwani, L. Walker, Tien L. Huang, 2004, European journal of medicinal chemistry.

Some non-conventional biomolecular targets for diamidines. A short survey.

Tien L. Huang, J. Vanden Eynde, A. Mayence, 2014, Bioorganic & medicinal chemistry.

Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug.

Tien L. Huang, Guangdi Wang, D. Rattendi, 2007, International journal of antimicrobial agents.

Synthesis and anti-pneumocystis carinii activity of piperidine-linked aromatic diimidazolines

James W. Smith, Tien L. Huang, I. Donkor, 1996 .

Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors.

Arvind Kumar, D. Boykin, D. Maciejewska, 2015, Bioorganic & medicinal chemistry.

Hydrolysis of Carbonates, Thiocarbonates, Carbamates, and Carboxylic Esters of α-Naphthol, β-Naphthol, and p-Nitrophenol by Human, Rat, and Mouse Liver Carboxylesterases

A. Székács, B. Hammock, Tien L. Huang, 1993, Pharmaceutical Research.

Peptidyl aldehyde inhibitors of calpain incorporating P2-proline mimetics.

Tien L. Huang, I. Donkor, Louis F. LeCour, 2003, Bioorganic & medicinal chemistry letters.

In Vitro Selection and In Vivo Efficacy of Piperazine- and Alkanediamide-Linked Bisbenzamidines against Pneumocystis Pneumonia in Mice

M. Cushion, P. Walzer, Tien L. Huang, 2006, Antimicrobial Agents and Chemotherapy.

Structure-Activity Relationships for Substrates and Inhibitors of Mammalian Liver Microsomal Carboxylesterases

B. Borhan, Qing X. Li, B. Hammock, 1996, Pharmaceutical Research.

Affinity purification of mouse liver carboxylesterases with trifluoromethyl ketones as ligands

B. Hammock, T. Shiotsuki, Tien L. Huang, 1994 .

Hepatic and pulmonary enzyme activities in horses.

J. Lakritz, B. Hammock, B. Winder, 2000, American journal of veterinary research.

Effect of Hepatotoxic Doses of Paracetamol and Carbon Tetrachloride on the Serum and Hepatic Carboxylesterase Activity in Mice *

B. Hammock, Tien L. Huang, S. A. Villalobos, 1993, The Journal of pharmacy and pharmacology.

Antitumor and Anti-Pneumocystis Carinii Activities of Novel Bisbenzamidines

M. Cushion, P. Walzer, Tien L. Huang, 2005, Medicinal Chemistry Research.