C. M. Sant’Anna

发表

Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors.

D. A. Rodrigues, Guilherme A. Ferreira-Silva, Ana C. S. Ferreira, 2016, Journal of medicinal chemistry.

The molecular basis for coxib inhibition of p38α MAP kinase

L. M. Lima, E. Barreiro, C. M. Sant’Anna, 2005 .

Non-competitive inhibitor of nucleoside hydrolase from Leishmania donovani identified by fragment-based drug discovery

P. Pascutti, L. M. Lima, E. Barreiro, 2016 .

Investigation of trypanothione reductase inhibitory activity by 1,3,4-thiadiazolium-2-aminide derivatives and molecular docking studies.

C. M. Sant’Anna, L. Leon, A. Tomás, 2012, Bioorganic & medicinal chemistry.

Modeling zinc-oxygen coordination in histone deacetylase: A comparison of semiempirical methods performance

D. A. Rodrigues, C. M. Sant’Anna, C. Fraga, 2018, International Journal of Quantum Chemistry.

Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IκB kinase-β.

N. Romeiro, E. Barreiro, C. M. Sant’Anna, 2011, European journal of medicinal chemistry.

Novel dialkylphosphorylhydrazones: Synthesis, leishmanicidal evaluation and theoretical investigation of the proposed mechanism of action.

M. S. Alexandre-Moreira, C. M. Sant’Anna, A. C. de Queiroz, 2015, European journal of medicinal chemistry.

Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant

Y. Cordeiro, C. M. Sant’Anna, A. Kümmerle, 2019, Journal of enzyme inhibition and medicinal chemistry.

Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors.

F. Totzke, M. Kubbutat, S. Laufer, 2014, European journal of medicinal chemistry.

Toward a platelet-activating factor pseudoreceptor: Semiempirical modeling of cation-π and hydrogen bond interactions in agonist binding☆

E. Barreiro, C. M. Sant’Anna, R. B. Alencastro, 1998 .

MOLECULAR MODELING ON PLATELET-ACTIVATING FACTOR (PAF) AND NEW PROPOSED PAF ANTAGONISTS

E. Barreiro, C. M. Sant’Anna, C. Fraga, 1996 .

Synthesis and biological evaluation of N-aryl-2-phenyl-hydrazinecarbothioamides: Experimental and theoretical analysis on tyrosinase inhibition and interaction with HSA.

C. M. Sant’Anna, A. Echevarria, J. Netto-Ferreira, 2018, Bioorganic chemistry.

Multi-Spectroscopic and Theoretical Analysis on the Interaction between Human Serum Albumin and a Capsaicin Derivative—RPF101

M. Tavares, C. M. Sant’Anna, J. Netto-Ferreira, 2018, Biomolecules.

Novel piperonal 1,3,4-thiadiazolium-2-phenylamines mesoionic derivatives: Synthesis, tyrosinase inhibition evaluation and HSA binding study.

C. M. Sant’Anna, A. Echevarria, J. Netto-Ferreira, 2018, International journal of biological macromolecules.

A Study of the Interaction Between trans-Dehydrocrotonin, a Bioactive Natural 19-nor-Clerodane, and Serum Albumin

C. M. Sant’Anna, J. Netto-Ferreira, M. Maciel, 2016 .

Studies of the Interaction between BSA and a Plumeran Indole Alkaloid Isolated from the Stem Bark of Aspidosperma cylindrocarpon (Apocynaceae)

C. M. Sant’Anna, J. Netto-Ferreira, R. Braz-Filho, 2016 .

An Unusual Intramolecular Halogen Bond Guides Conformational Selection.

M. E. Beck, M. D. Polêto, F. Ferreira, 2018, Angewandte Chemie.

Quantitative Structure–Property Relationship (QSPR) Models for a Local Quantum Descriptor: Investigation of the 4- and 3-Substituted-Cinnamic Acid Esterification

M. G. Nascimento, C. M. Sant’Anna, A. Echevarria, 2015, Molecules.

Molecular modeling of novel 1H-pyrazolo[3,4-b]pyridine derivatives designed as isosters of the antimalarial mefloquine

E. Barreiro, C. R. Rodrigues, C. M. Sant’Anna, 2002 .

Novel 3,4-methylenedioxyde-6-X-benzaldehyde-thiosemicarbazones: Synthesis and antileishmanial effects against Leishmania amazonensis.

C. M. Sant’Anna, A. Echevarria, E. C. Torres-Santos, 2015, European journal of medicinal chemistry.

Biological interactions of fluorinated chalcones: Stimulation of tyrosinase activity and binding to bovine serum albumin

C. M. Sant’Anna, J. Netto-Ferreira, O. Chaves, 2017 .

Synthesis, tyrosinase inhibition and transportation behavior of novel β-enamino thiosemicarbazide derivatives by human serum albumin

C. M. Sant’Anna, A. Echevarria, J. Netto-Ferreira, 2018 .

Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases

T. Kronenberger, D. A. Rodrigues, C. M. Sant’Anna, 2022, Biomolecules.

New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: quantitative structure-activity relationship studies.

E. Barreiro, E. Castellano, A. Denicola, 2005, Bioorganic & medicinal chemistry.

SYNTHESIS, CHARACTERIZATION, MOLECULAR MODELING AND BIOLOGICAL ACTIVITY AGAINST ARTEMIA SALINA OF NEW SYMMETRICAL BISPHOSPHORAMIDATES

C. M. Sant’Anna, V. D. dos Santos, J. B. N. DaCosta, 2004 .

Theoretical and experimental characterization of 1,4-N⋯S σ-hole intramolecular interactions in bioactive N-acylhydrazone derivatives

G. Ferreira, D. A. Rodrigues, C. M. Sant’Anna, 2018 .

Docking, Synthesis and Antiproliferative Activity of N-Acylhydrazone Derivatives Designed as Combretastatin A4 Analogues

L. M. Lima, E. Barreiro, R. Chammas, 2014, PloS one.

LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A2A Receptor

M. Martins, E. Barreiro, C. M. Sant’Anna, 2017, Front. Pharmacol..

A novel 3D-QSAR comparative molecular field analysis (CoMFA) model of imidazole and quinazolinone functionalized p38 MAP kinase inhibitors.

G. M. Sperandio da Silva, E. Barreiro, C. M. Sant’Anna, 2004, Bioorganic & medicinal chemistry.

Studies on diastereoselective reduction of cyclic β-ketoesters with boron hydrides. Part 4: The reductive profile of functionalized cyclohexanone derivatives

E. Barreiro, C. M. Sant’Anna, C. Fraga, 2004 .

Regioselective microwave synthesis and derivatization of 1,5-diaryl-3-amino-1,2,4-triazoles and a study of their cholinesterase inhibition properties

C. M. Sant’Anna, A. Kümmerle, Thiago M. Pereira, 2019, RSC advances.

Diastereoselective Synthesis of New Dialkylphosphorylhydrazones

C. M. Sant’Anna, V. Rumjanek, J. Rodrigues, 2009 .

Binding studies of lophirone B with bovine serum albumin (BSA): Combination of spectroscopic and molecular docking techniques

C. M. Sant’Anna, J. Netto-Ferreira, O. Chaves, 2017 .

Structure-Based Discovery of Thiosemicarbazone Metalloproteinase Inhibitors for Hemorrhage Treatment in Snakebites.

C. M. Sant’Anna, D. Lopes, F. B. Ferreira, 2017, ACS medicinal chemistry letters.

Structural characterization, analysis of hindered rotation and cytotoxic activity of N2 ,N4 ,N6 -triphenethyl-1,3,5-triazine-2,4,6-triamine

C. M. Sant’Anna, V. Almeida, A. Echevarria, 2021, Spectroscopy Letters.

Development of new CoMFA and CoMSIA 3D-QSAR models for anti-inflammatory phthalimide-containing TNFalpha modulators.

N. Romeiro, E. Barreiro, C. M. Sant’Anna, 2006, Bioorganic & medicinal chemistry.

Evaluating the interaction between di-fluorinated chalcones and plasmatic albumin

C. M. Sant’Anna, J. Netto-Ferreira, O. Chaves, 2016 .

Design, Synthesis, and Pharmacological Evaluation of First‐in‐Class Multitarget N‐Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors

D. A. Rodrigues, C. M. Sant’Anna, C. A. Fraga, 2020, ChemMedChem.

Solvent-Free Synthesis, DNA-Topoisomerase II Activity and Molecular Docking Study of New Asymmetrically N,N'-Substituted Ureas

C. M. Sant’Anna, A. Echevarria, D. da Silva, 2012, Molecules.

Semiempirical calculations on the mechanism of stereoselective NaBH4 reduction of 2-methoxycarbonyl-2-allyl-cyclopentanone

E. Barreiro, C. M. Sant’Anna, C. Fraga, 1995 .

5-Enolpyruvylshikimate-3-phosphate synthase: determination of the protonation state of active site residues by the semiempirical method.

C. M. Sant’Anna, Anivaldo Xavier de Souza, C. M. R. Sant’Anna, 2008, Bioorganic chemistry.

A novel scaffold for EGFR inhibition: Introducing N-(3-(3-phenylureido)quinoxalin-6-yl) acrylamide derivatives

S. Laufer, L. M. Lima, E. Barreiro, 2019, Scientific Reports.

Fluorescence and Docking Studies of the Interaction between Human Serum Albumin and Pheophytin

A. Amorim, C. M. Sant’Anna, J. Netto-Ferreira, 2015, Molecules.

Brazoides A-D, New Alkaloids from Justicia gendarussa Burm. F. Species

C. M. Sant’Anna, M. O. Moraes, R. Braz-Filho, 2016 .

Theoretical and Experimental Studies of the Interaction between Human Serum Albumin and Artepillin C, an Active Principle of the Brazilian Green Propolis

C. M. Sant’Anna, J. Netto-Ferreira, R. N. Castro, 2019, Revista Virtual de Química.

Cloning and expression of trypanothione reductase from a New World Leishmania species

A. Gonçalves, C. M. Sant’Anna, L. Leon, 2008, Archives of Microbiology.

Dialkylphosphorylhydrazones as potent tyrosinase inhibitors

C. M. Sant’Anna, V. Rumjanek, Marcia C C DE Oliveira, 2012 .

Probing the interaction between 7-O-β-d-glucopyranosyl-6-(3-methylbut-2-enyl)-5,4′-dihydroxyflavonol with bovine serum albumin (BSA)

C. M. Sant’Anna, J. Netto-Ferreira, O. Chaves, 2017 .

Structural insights into cholinesterases inhibition by harmane β-carbolinium derivatives: a kinetics-molecular modeling approach.

D. R. Silva, C. M. Sant’Anna, V. Rumjanek, 2012, Phytochemistry.