Laixing Hu

发表

Synthesis and structure-activity relationships of carbazole sulfonamides as a novel class of antimitotic agents against solid tumors.

Jian-Dong Jiang, Y. Ling, Laixing Hu, 2006, Journal of medicinal chemistry.

Structural Based Screening of Antiandrogen Targeting Activation Function-2 Binding Site

Jinming Zhou, S. Cen, Laixing Hu, 2018, Front. Pharmacol..

Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents.

Zhi-Hong Jiang, Laixing Hu, Zhuorong Li, 2020, Bioorganic chemistry.

Novel carbazole sulfonamide derivatives of antitumor agent: Synthesis, antiproliferative activity and aqueous solubility.

Laixing Hu, Lianqi Sun, Yan-bin Wu, 2017, Bioorganic & medicinal chemistry letters.

The efficacy of novel arylimidamides against Trypanosoma cruzi in vitro

Arvind Kumar, D. Boykin, Laixing Hu, 2011, Parasitology.

Synthesis of novel substituted N-aryl benzamides as hA3G stabilizers and their inhibitory activities against hepatitis C virus replication

Jian-Dong Jiang, Laixing Hu, Zhou-yi Wu, 2013 .

Novel potent antimitotic heterocyclic ketones: synthesis, antiproliferative activity, and structure-activity relationships.

D. Boykin, Jian-Dong Jiang, Laixing Hu, 2007, Bioorganic & medicinal chemistry letters.

3-(2'-Bromopropionylamino)-benzamides as novel S-phase arrest agents.

D. Boykin, Jian-Dong Jiang, Laixing Hu, 2007, Bioorganic & medicinal chemistry letters.

Identification of small molecule compounds targeting the interaction of HIV-1 Vif and human APOBEC3G by virtual screening and biological evaluation

Zhenlong Liu, Jinming Zhou, Fei Guo, 2018, Scientific Reports.

Synthesis and in vitro activity of asymmetric indole-based bisamidine compounds against Gram-positive and Gram-negative pathogens.

Xuefu You, Laixing Hu, Yan-bin Wu, 2019, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro activity of dicationic indolyl diphenyl ethers as novel potent antibiotic agents against drug-resistant bacteria.

Xuefu You, Laixing Hu, Yan-bin Wu, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship of dicationic diaryl ethers as novel potent anti-MRSA and anti-VRE agents.

D. Boykin, Laixing Hu, Maureen L Kully, 2009, Bioorganic & medicinal chemistry letters.

Optimization of the central linker of dicationic bis-benzimidazole anti-MRSA and anti-VRE agents.

D. Boykin, Laixing Hu, Maureen L Kully, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro activity of dicationic bis-benzimidazoles as a new class of anti-MRSA and anti-VRE agents.

D. Boykin, Laixing Hu, Maureen L Kully, 2009, Bioorganic & medicinal chemistry letters.

Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif.

P. Peixoto, C. Bailly, W. Wilson, 2007, Journal of the American Chemical Society.

Novel pyridinyl and pyrimidinylcarbazole sulfonamides as antiproliferative agents.

D. Boykin, Jian-Dong Jiang, Laixing Hu, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents

Arvind Kumar, D. Boykin, Xiaohua Zhu, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum.

W. Wilson, D. Boykin, Laixing Hu, 2009, Bioorganic & medicinal chemistry.

Azaterphenyl diamidines as antileishmanial agents.

W. Wilson, D. Boykin, Laixing Hu, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents.

Laixing Hu, Lianqi Sun, Yan-bin Wu, 2020, European journal of medicinal chemistry.

Synthesis and structure-activity relationship study of new biaryl amide derivatives and their inhibitory effects against hepatitis C virus

S. Cen, Laixing Hu, Zonggen Peng, 2021, European Journal of Medicinal Chemistry.

Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues.

W. Wilson, D. Boykin, Laixing Hu, 2013, Bioorganic & medicinal chemistry.

The antitumor activity and preliminary modeling on the potential mechanism of action of human peroxiredoxin-5

Zhao-yong Yang, Laixing Hu, Xiaozhou Feng, 2017, Oncotarget.

Identification of Triptophenolide from Tripterygium wilfordii as a Pan-antagonist of Androgen Receptor.

Jinming Zhou, S. Cen, Laixing Hu, 2016, ACS medicinal chemistry letters.

N-(2,6-Dimethoxypyridine-3-yl)-9-Methylcarbazole-3-Sulfonamide as a Novel Tubulin Ligand against Human Cancer

R. Shao, Wei-Jia Kong, Jian-Dong Jiang, 2008, Clinical Cancer Research.

Synthesis and structure-activity relationship of novel bisindole amidines active against MDR Gram-positive and Gram-negative bacteria.

Xuefu You, Laixing Hu, Yan-bin Wu, 2018, European journal of medicinal chemistry.

Identification of small molecule compounds targeting the interaction of HIV-1 Vif and human APOBEC3G by virtual screening and biological evaluation

Zhenlong Liu, Jinming Zhou, Fei Guo, 2018, Scientific Reports.

Novel carbazole sulfonamide microtubule-destabilizing agents exert potent antitumor activity against esophageal squamous cell carcinoma.

Xiaohang Zhao, Laixing Hu, Lanping Zhou, 2018, Cancer letters.

Novel diaryl or heterocyclic sulfonamides as antimitotic agents.

Jian-Dong Jiang, Laixing Hu, Zhuo-rong Li, 2008, Anti-cancer agents in medicinal chemistry.

Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif.

P. Peixoto, C. Bailly, D. Boykin, 2007, Journal of the American Chemical Society.