D. Macpherson

发表

BACE-1 inhibitors part 3: identification of hydroxy ethylamines (HEAs) with nanomolar potency in cells.

D. Riddell, C. Dingwall, Christopher N. Johnson, 2008, Bioorganic & medicinal chemistry letters.

BACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs).

D. Riddell, C. Dingwall, J. Mosley, 2008, Bioorganic & medicinal chemistry letters.

BACE-1 inhibitors part 2: identification of hydroxy ethylamines (HEAs) with reduced peptidic character.

D. Riddell, C. Dingwall, J. Mosley, 2008, Bioorganic & medicinal chemistry letters.

Solid phase sequential 1,3-dipolar cycloaddition–Pictet–Spengler reactions

R. Grigg, D. Macpherson, H. Dondas, 2000 .

4.04 – Functions Bearing Two Oxygens, R12C(OR2)2

D. Macpherson, H. Rami, 1995 .

Discovery of N-(3-fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate.

A. Muir, G. Sanger, Christopher N. Johnson, 2009, Journal of medicinal chemistry.

Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia.

C. Large, D. Derjean, D. Owen, 2020, ACS medicinal chemistry letters.

Sodium Channel Blockers for the Treatment of Pain

D. Macpherson, D. Witty, Gerard Giblin, 2017 .

The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor.

Michael A. Briggs, G. Macdonald, G. Sanger, 2008, Bioorganic & medicinal chemistry letters.

GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility.

A. Muir, G. Sanger, P. Hellström, 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

On the utility of S-mesitylsulfinimines for the stereoselective synthesis of chiral amines and aziridines.

D. Macpherson, I. Churcher, R. Stockman, 2011, Chemical communications.

Conjugate addition to the ethylene ketal of 2-carbomethoxy-2-cyclopentenone a synthesis of sarkomycin

D. Macpherson, A. Hewson, 1983 .

Sequential 1,3-Dipolar Cycloaddition-Pictet–Spengler Reactions. A Versatile Tactical Combination

R. Grigg, D. Macpherson, M. Thornton-Pett, 2000 .

[4+3] cycloaddition of a trimethylenemethane fragment: an approach to polyhydroazulenes

B. Trost, D. Macpherson, 1987 .

Convenient synthesis of chiral non-racemic S-mesityl sulfinimines

D. Macpherson, R. Stockman, Leonid Sasraku-Neequaye, 2008 .

Synthesis and antifungal activity of C-16 oximino and vinyl amphotericin B derivatives.

D. Macpherson, D. F. Corbett, D. Dean, 1995, The Journal of antibiotics.

Pd-Catalyzed Cycloisomerization to 1,2-Dialkylidenecycloalkanes .1.

B. Trost, D. Macpherson, M. Lautens, 1994 .

Total synthesis of cyclopentanoid natural products

D. Macpherson, A. Hewson, 1985 .

Synthesis of Vixotrigine, a Use-Dependent Sodium Channel Blocker. Part 1: Development of Bulk Supply Routes to Enable Proof of Concept

Gerard M P Giblin, Adrian Heseltine, William F. Kiesman, 2020 .

Synthesis of 16-decarboxy-16-hydroxymethyl amphotericin B - a novel antifungal agent

D. Macpherson, W. S. MacLachlan, M. Driver, 1992 .

A versatile strategy for the derivatisation of the carboxy group of amphotericin B: the preparation of C-16 ketone analogues

D. Macpherson, M. Driver, A. R. Greenlees, 1992 .

Pictet–Spengler/Palladium Catalyzed Allenylation and Carbonylation Processes

R. Grigg, D. Macpherson, M. Thornton-Pett, 2000 .

GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility

Erik Näslund, A. Muir, E. Näslund, 2009 .

Potent oxadiazole CGRP receptor antagonists for the potential treatment of migraine.

Michael A. Briggs, David M. Wilson, I. Wall, 2010, Bioorganic & medicinal chemistry letters.

Regioselective synthesis of N-aminoisoindolones and mono-N- and di-N,N'-substituted phthalazones utilizing hydrazine nucleophiles in a palladium-catalyzed three-component cascade process.

R. Grigg, D. Macpherson, P. Milner, 2008, The Journal of organic chemistry.

Pd‐Catalyzed Cycloisomerization to 1,2‐Dialkylidenecycloalkanes. Part 1.

Candace K. Chan, B. Trost, D. Macpherson, 1994 .

Adventures in Polyene Macrolide Chemistry: The Derivatization of Amphotericin B

D. Macpherson, D. F. Corbett, W. S. MacLachlan, 1993 .