J. Hubbard

发表

Second generation of BACE-1 inhibitors part 3: Towards non hydroxyethylamine transition state mimetics.

C. Dingwall, J. Mosley, P. Rowland, 2009, Bioorganic & medicinal chemistry letters.

Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics.

C. Dingwall, J. Mosley, P. Rowland, 2009, Bioorganic & medicinal chemistry letters.

Second generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituent.

C. Dingwall, J. Mosley, P. Rowland, 2009, Bioorganic & medicinal chemistry letters.

NMR analysis of main-chain conformational preferences in an unfolded fibronectin-binding protein.

C. Dobson, C. Penkett, L. J. Smith, 1997, Journal of molecular biology.

Functional size measurements of the ubiquinol oxidase activity of the cytochrome o terminal oxidase complex of Escherichia coli.

R. Poole, J. Hubbard, H. Williams, 1991, The Biochemical journal.

The uptake of silver ions by Escherichia coli K12: toxic effects and interaction with copper ions

M. N. Hughes, R. Poole, J. Hubbard, 1988, Applied Microbiology and Biotechnology.

Synthesis and evaluation of novel alpha-amino cyclic boronates as inhibitors of HCV NS3 protease.

Z. Ni, P. Rowland, S. Baker, 2010, Bioorganic & medicinal chemistry letters.

Effects of iron-limitation ofEscherichia coli on growth, the respiratory chains and gallium uptake

M. N. Hughes, R. Poole, J. Hubbard, 1986, Archives of Microbiology.

Effects of low environmental manganese concentrations on the respiratory chains of Paracoccus denitrificans

M. N. Hughes, R. Poole, J. Hubbard, 1990 .

Resonance Raman spectroscopy of an oxygenated intermediate species of cytochrome oxidase d from Escherichia coli

M. N. Hughes, R. Poole, J. Hubbard, 1982 .

Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1β1γ1).

Jon R. Wilson, B. Xiao, J. Hubbard, 2018, Methods in molecular biology.

Functional heterogeneity in the reaction centre photochemistry of Rhodopseudomonas viridis at cryogenic temperatures

J. Hubbard, M. Evans, 1990 .

Electron donation by the high‐potential haems in Rhodopseudomonas viridis reaction centres at low temperatures

J. Hubbard, M. Evans, J. Hubbard, 1989 .

Introduction to the NMR of proteins.

J. Hubbard, D. Reid, L. K. MacLachlan, 1997, Methods in molecular biology.

P‐700 photooxidation in state 1 and state 2 in cyanobacteria upon flash illumination with phycobilin‐ and chlorophyll‐absorbed light

N. Tsinoremas, John F. Allen, J. Hubbard, 1989 .

Selective and dual action orally active inhibitors of thrombin and factor Xa.

Stefan Senger, S. Senger, M. Convery, 2007, Bioorganic & medicinal chemistry letters.

Effects of copper concentration in continuous culture on the aa3-type cytochrome oxidase and respiratory chains of Paracoccus denitrificans

M. N. Hughes, R. Poole, J. Hubbard, 1989, Archives of Microbiology.

Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells

Robin J. W. Willows, Jon R. Wilson, S. Gamblin, 2017, The Biochemical journal.

Properties of the Photosystem II electron acceptor complex of Phormidium laminosum

J. Hubbard, M. Evans, J. Nugent, 1989 .

Identification of the epitopes of calcitonin gene‐related peptide (CGRP) for two anti‐CGRP monoclonal antibodies by 2D NMR

C. Dobson, D. Raleigh, J. Bonnerjea, 1997, Protein science : a publication of the Protein Society.

Structural and dynamical characterization of a biologically active unfolded fibronectin-binding protein from Staphylococcus aureus.

C. Dobson, C. Penkett, R. Smith, 1998, Biochemistry.

Purification and partial characterization of two cytochrome oxidases (caa3 and o) from the thermophilic bacterium PS3.

R. Poole, J. Hubbard, B. S. Baines, 1984, Biochimica et Biophysica Acta.

Partial purification and characterization of a soluble haemoprotein, having spectral properties similar to cytochrome a 1, from anaerobically grown Escherichia coli

R. Poole, J. Hubbard, H. Williams, 1984 .

Backbone resonance assignments of the catalytic and regulatory domains of Ca2+/calmodulin-dependent protein kinase 1D

S. Knapp, C. Ludwig, F. Berditchevski, 2020, Biomolecular NMR Assignments.

Nuclear magnetic resonance spectroscopy reveals the functional state of the signalling protein CheY in vivo in Escherichia coli

A. Fosberry, J. Hubbard, L. K. MacLachlan, 2003, Molecular microbiology.

Nitrate, but not silver, ions induce spectral changes in Escherichia coli cytochrome d

M. N. Hughes, R. Poole, J. Hubbard, 1983, FEBS letters.

Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin.

N. C. Price, S. Martin, S. Kelly, 1991, The Biochemical journal.

Global Analysis of Proteins Synthesized by Mycobacterium smegmatis Provides Direct Evidence for Physiological Heterogeneity in Stationary-Phase Cultures

J. Hubbard, H. Williams, M. J. Smeulders, 2005, Journal of bacteriology.

On the role of the C-terminus of alpha-calcitonin-gene-related peptide (alpha CGRP). The structure of des-phenylalaninamide37-alpha CGRP and its interaction with the CGRP receptor.

C. Dobson, N. C. Price, D. Raleigh, 1993, The Biochemical journal.

Unlocking the secrets of the gatekeeper: methods for stabilizing and crystallizing GPCRs.

Shweta Singh, Michael M Hann, Bernadette Byrne, 2013, Biochimica et biophysica acta.

Loss of constitutive activity is correlated with increased thermostability of the human adenosine A2A receptor

S. Dowell, B. Byrne, Shweta Singh, 2013, British journal of pharmacology.

A method for identification of inhibitors of the phosphorylation reactions of bacterial response regulator proteins using (31)P nuclear magnetic resonance spectroscopy.

A. Fosberry, J. Hubbard, S. Findlow, 2001, Analytical biochemistry.

Pathogenicity and Histidine Kinases: Approaches Toward the Development of a New Generation of Antibiotics

J. Hubbard, J. Throup, M. Burnham, 2003 .

Stefan Senger, S. Senger, M. Convery, 2007, Bioorganic & medicinal chemistry letters.

Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates.

William McDowell, Yang Liu, Dazhong Fan, 2010, Bioorganic & medicinal chemistry letters.

The determination of protonation states in proteins.

J. Helliwell, J. Hubbard, M. Blakeley, 2007, Acta crystallographica. Section D, Biological crystallography.

Direct electrochemical studies of ligand-binding reactions to cytochrome c oxidase

Z. Shu, J. Hubbard, A. E. Cass, 1986 .

Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics.

C. Dingwall, J. Mosley, P. Rowland, 2009, Bioorganic & medicinal chemistry letters.