D. Egan

发表

Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases

B. Creaven, B. Duff, D. Egan, 2010 .

In vitro cytotoxic potential and mechanism of action of selected coumarins, using human renal cell lines.

B. Creaven, D. Egan, G. Finn, 2002, Cancer letters.

A study of the role of cell cycle events mediating the action of coumarin derivatives in human malignant melanoma cells.

B. Creaven, D. Egan, G. Finn, 2004, Cancer letters.

Role of cell cycle events and apoptosis in mediating the anti-cancer activity of a silver(I) complex of 4-hydroxy-3-nitro-coumarin-bis(phenanthroline) in human malignant cancer cells.

M. Devereux, B. Creaven, D. Egan, 2009, European journal of pharmacology.

An in vitro investigation of the induction of apoptosis and modulation of cell cycle events in human cancer cells by bisphenanthroline-coumarin-6,7-dioxacetatocopper(II) complex.

B. Creaven, D. Egan, K. Kavanagh, 2007, Chemico-biological interactions.

In vitro cancer chemotherapeutic activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)]x2H2O, [Cu(phen)2(mal)]x2H2O and [Mn(phen)2(mal)]x2H2O (malH2=malonic acid) using human cancer cells.

M. Devereux, D. Egan, M. Mccann, 2007, Cancer letters.

Apoptotic cell death: a possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa)(phen)(2)] (phen=phenanthroline, 4-Mecdoa=4-methylcoumarin-6,7-dioxactetate), in human malignant cancer cells.

B. Creaven, D. Egan, K. Kavanagh, 2007, European journal of pharmacology.

In vitro anti-tumour effect of 1,10-phenanthroline-5,6-dione (phendione), [Cu(phendione)3](ClO4)2.4H2O and [Ag(phendione)2]ClO4 using human epithelial cell lines.

M. Devereux, D. Egan, M. Mccann, 2006, Chemico-biological interactions.

Activation of mitogen activated protein kinase pathways and melanogenesis by novel nitro-derivatives of 7-hydroxycomarin in human malignant melanoma cells.

B. Creaven, D. Egan, G. Finn, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Differential pulse voltammetric determination of 7-hydroxycoumarin in human urine.

M. Smyth, R. O'Kennedy, J. Wang, 1993, Journal of pharmaceutical and biomedical analysis.

Modulation of mitogen-activated protein kinases by 6-nitro-7-hydroxycoumarin mediates apoptosis in renal carcinoma cells.

B. Creaven, D. Egan, G. Finn, 2003, European journal of pharmacology.

Spectroscopic studies, DFT calculations, and cytotoxic activity of novel silver(I) complexes of hydroxy ortho-substituted-nitro-2H-chromen-2-one ligands and a phenanthroline adduct.

I. Georgieva, M. Devereux, S. McClean, 2015, Journal of inorganic biochemistry.

Direct colorimetric monoclonal antibody enzyme immunoassay for estradiol-17 beta in saliva.

D. Egan, J. Gosling, P. Fottrell, 1997, Clinical chemistry.

Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag2(NH3)2(salH)2] (salH2=salicylic acid).

M. Devereux, V. McKee, N. Kayal, 2004, Journal of inorganic biochemistry.

Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH2) and 3,3-Dimethylpentanedioic acid(3dmepdaH2): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)]2· 6H2O and [Cu(2dmepda)(bipy)(EtOH)]2· 4EtOH (bipy = 2,2′Bipyridine)

D. Naughton, M. Devereux, V. McKee, 2006, Bioinorganic chemistry and applications.

Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4'-thiazolyl)benzimidazole[thiabendazole]: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH=thiabendazole).

M. Devereux, V. McKee, D. Egan, 2004, Journal of inorganic biochemistry.

Daphnetin induced differentiation of human renal carcinoma cells and its mediation by p38 mitogen-activated protein kinase.

B. Creaven, D. Egan, G. Finn, 2004, Biochemical pharmacology.

Studies on the cytostatic and cytotoxic effects and mode of action of 8-nitro-7-hydroxycoumarin.

D. Egan, P. James, D. Cooke, 1997, Cancer letters.

Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2].8.8H(2)O and [Cu(4-Mecdoa)(phen)2].13H2O (phen=1,10-phenant

B. Creaven, D. Egan, K. Kavanagh, 2007, Journal of inorganic biochemistry.

RETRACTED: A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells.

M. Devereux, B. Creaven, D. Egan, 2007, Cancer Letters.

RETRACTED: In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines

M. Devereux, B. Creaven, D. Egan, 2007 .

Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes

B. Creaven, D. Egan, K. Kavanagh, 2006 .

Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc)2(H2O)2] · 2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)

B. Creaven, D. Egan, K. Kavanagh, 2005 .

Investigation of intracellular signalling events mediating the mechanism of action of 7-hydroxycoumarin and 6-nitro-7-hdroxycoumarin in human renal cells.

B. Creaven, D. Egan, G. Finn, 2004, Cancer letters.

Study of the in vitro cytotoxic potential of natural and synthetic coumarin derivatives using human normal and neoplastic skin cell lines

B. Creaven, D. Egan, G. Finn, 2001, Melanoma research.

The pharmacology, metabolism, analysis, and applications of coumarin and coumarin-related compounds.

D. Egan, R O'Kennedy, E Prosser, 1990, Drug metabolism reviews.

Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands.

M. Devereux, A. Kellett, D. Egan, 2007, Journal of inorganic biochemistry.

Mechanism of action of coumarin and silver(I)-coumarin complexes against the pathogenic yeast Candida albicans.

B. Creaven, D. Egan, K. Kavanagh, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Anti-Cancer Activity and Mutagenic Potential of Novel Copper (II) Quinolinone Schiff Base Complexes in Hepatocarinoma Cells

B. Creaven, B. Duff, D. Egan, 2019 .

Molecular and cellular pharmacology Anti-cancer activity and mutagenic potential of novel copper ( II ) quinolinone Schiff base complexes in hepatocarcinoma cells

B. Creaven, B. Duff, D. Egan, 2016 .

Spectrofluorimetric method for the quantification of 7-hydroxycoumarin in urine and plasma using both extracted and unextracted samples.

D. Egan, R. O’Kennedy, 1993, The Analyst.

Rapid and sensitive determination of coumarin and 7-hydroxycoumarin and its glucuronide conjugate in urine and plasma by high-performance liquid chromatography.

D. Egan, R. O’Kennedy, 1992, Journal of chromatography.

[Ag2(aca)2]n and [Ag4(aca)4(NH3)2] (acaH = 9-anthracenecarboxylic acid): Synthesis, X-ray crystal structures, antimicrobial and anti-cancer activities

M. Devereux, V. McKee, B. Creaven, 2007 .

Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity.

M. Morgan, B. Duff, D. Egan, 2011, Journal of inorganic biochemistry.

Development of an antibody-based biosensor for determination of 7-hydroxycoumarin (umbelliferone) using horseradish peroxidase labelled anti-7-hydroxycoumarin antibody

M. Smyth, E. Dempsey, D. Egan, 1994 .

A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity.

M. Morgan, M. Brennan, A. Chubb, 2013, Journal of inorganic biochemistry.

Synthesis and X-ray diffraction structures of novel half-sandwich Os(II)-and Ru(II)-hydroxamate complexes

B. Duff, D. Egan, P. Buglyó, 2012 .

Evaluation of a modified carbon micromesh electrode as a new substrate for electrochemical immunosensing

E. Dempsey, D. Egan, D. Rathod, 2011 .

Platinum nanoparticle decoration of carbon materials with applications in non-enzymatic glucose sensing

C. Dickinson, E. Dempsey, D. Egan, 2010 .

THE PHARMACOLOGY. METABOLISM. ANALYSIS. AND APPLICATIONS OF COMPOUNDS* COUMARIN AND COUMARIN4ELATED

D. Egan, 1991 .

Antibody-based approaches to coumarin analysis

M. Smyth, E. Dempsey, D. Egan, 2005, Journal of Cancer Research and Clinical Oncology.

A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity.

D. Egan, D. Griffith, C. Marmion, 2013, Journal of inorganic biochemistry.

Development of an antibody-based amperometric biosensor to study the reaction of 7-hydroxycoumarin with its specific antibody.

M. Smyth, J. Wang, E. Dempsey, 1993, The Analyst.