Hai-Kui Yang

发表

Synthesis, antiproliferative evaluation, and structure–activity relationships of novel triazole–isoindoline hybrids bearing 3,4,5-trimethoxyphenyl moiety

Maohui Luo, Qiu Li, Peng-Ju Chen, 2018, Chemical Papers.

Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.

R. Neve, R. Mackman, Xiaowu Chen, 2019, Bioorganic & Medicinal Chemistry.

Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.

R. Neve, R. Mackman, Xiaowu Chen, 2019, Bioorganic & medicinal chemistry.

Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study.

M. Desai, R. Jordan, R. Mackman, 2015, Journal of medicinal chemistry.

Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle.

J. Chiva, R. Mackman, T. Appleby, 2018, Journal of medicinal chemistry.

Design, synthesis and antiproliferative activity of novel substituted 2-amino-7,8-dihydropteridin-6(5H)-one derivatives.

Qiu Li, Hai-Kui Yang, Wen-wei You, 2017, Bioorganic & medicinal chemistry letters.

One-pot synthesis and antiproliferative activity of novel 2,4-diaminopyrimidine derivatives bearing piperidine and piperazine moieties.

Hai-Kui Yang, Wen-wei You, Meng-Jin Hu, 2014, European journal of medicinal chemistry.

Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety.

Hai-Kui Yang, Wen-wei You, Min Zou, 2012, Bioorganic & medicinal chemistry letters.

Efficient One-Pot Synthesis of 3-Amino-7-azaindoles Under Microwave Irradiation

Zhi-Hong Jiang, Hai-Kui Yang, Wen-wei You, 2014 .

Facile one-pot synthesis, antiproliferative evaluation and structure-activity relationships of 3-amino-1H-indoles and 3-amino-1H-7-azaindoles.

Hai-Kui Yang, Wen-wei You, Meng-Jin Hu, 2019, Bioorganic chemistry.

Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines.

Huijun Sun, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of novel alkylsulfanyl-1,2,4-triazoles as cis-restricted combretastatin A-4 analogues.

Qiu Li, Hai-Kui Yang, Wen-wei You, 2017, European journal of medicinal chemistry.

Corrigendum to “Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety” [Bioorg. Med. Chem. Lett. 22/13 (2012) 4471–4474]

Hai-Kui Yang, Wen-wei You, Min Zou, 2015 .

Design, Synthesis and Molecular Docking Studies of Novel Indole–Pyrimidine Hybrids as Tubulin Polymerization Inhibitors

Hai-Kui Yang, Wen-wei You, Meng-Jin Hu, 2015, Chemical biology & drug design.