Shu-Qing Wang

发表

Novel Inhibitor Design for Hemagglutinin against H1N1 Influenza Virus by Core Hopping Method

K. Chou, Xiaobo Li, Shu-Qing Wang, 2011, PloS one.

Pallidifloside D, a saponin glycoside constituent from Smilax riparia, resist to hyperuricemia based on URAT1 and GLUT9 in hyperuricemic mice.

J. Ruan, Shu-Qing Wang, Xiao-hui Wu, 2014, Journal of ethnopharmacology.

Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics

K. Chou, Shu-Qing Wang, Wei-Ren Xu, 2013, Drug design, development and therapy.

Identification of novel PPARα/γ dual agonists by virtual screening, ADMET prediction and molecular dynamics simulations

Shu-Qing Wang, Wei-Ren Xu, Ying-Hong Ma, 2018, Journal of biomolecular structure & dynamics.

Design Novel Dual Agonists for Treating Type-2 Diabetes by Targeting Peroxisome Proliferator-Activated Receptors with Core Hopping Approach

K. Chou, Shu-Qing Wang, Wei-Ren Xu, 2012, PloS one.

Study of drug resistance of chicken influenza A virus (H5N1) from homology-modeled 3D structures of neuraminidases.

K. Chou, Q. Du, Shu-Qing Wang, 2007, Biochemical and biophysical research communications.

Insights from investigating the interaction of oseltamivir (Tamiflu) with neuraminidase of the 2009 H1N1 swine flu virus.

K. Chou, Dawei Zhang, Q. Du, 2009, Biochemical and biophysical research communications.

Docking and molecular dynamics simulations of peroxisome proliferator activated receptors interacting with pan agonist sodelglitazar.

Kuo-Chen Chou, Wei-Ren Xu, Run-Ling Wang, 2011, Protein and peptide letters.

Designing Inhibitors of M2 Proton Channel against H1N1 Swine Influenza Virus

Kuo-Chen Chou, Ri-Bo Huang, Qi-Shi Du, 2010, PloS one.

2L-PCA: a two-level principal component analyzer for quantitative drug design and its applications

Kuo-Chen Chou, Ri-Bo Huang, Qi-Shi Du, 2017, Oncotarget.

The derivatives of oseltamivir design passing through the important cleft of neuraminidase against influenza virus by de novo design

Shu-Qing Wang, Runling Wang, Wei-bing Zhang, 2014 .

Virtual identification of novel PPARα/γ dual agonists by scaffold hopping of saroglitazar

Shu-Qing Wang, Wei-Ren Xu, Xin Liu, 2018, Journal of biomolecular structure & dynamics.

Design, sythesis and evaluation of a series of 3- or 4-alkoxy substituted phenoxy derivatives as PPARs agonists

Z. Shen, Yi Huan, Shu-Qing Wang, 2017, Oncotarget.

Anticancer Melatplatin Prodrugs: High Effect and Low Toxicity, MT1-ER-target and Immune Response In vivo.

Shu-Qing Wang, Zhong-Ying Ma, Cheng-Zhi Xie, 2020, Journal of medicinal chemistry.

Synthesis, evaluation, molecular dynamics simulation and targets identification of novel pyrazole-containing imide derivatives

Shu-Qing Wang, Runling Wang, Ying-Hong Ma, 2020, Journal of biomolecular structure & dynamics.

Scaffold-Based Pan-Agonist Design for the PPARα, PPARβ and PPARγ Receptors

Shu-Qing Wang, Wei-Ren Xu, Runling Wang, 2012, PloS one.

SAHA-based novel HDAC inhibitor design by core hopping method.

Xiaobo Li, Shu-Qing Wang, Wei-Ren Xu, 2014, Journal of molecular graphics & modelling.

Molecular docking, 3D-QSAR and structural optimization on imidazo-pyridine derivatives dually targeting AT1 and PPARγ

Shu-Qing Wang, Wei-Ren Xu, Runling Wang, 2017, Oncotarget.

In Depth Analysis on the Binding Sites of Adamantane Derivatives in HCV (Hepatitis C Virus) p7 Channel Based on the NMR Structure

Q. Du, Ri-Bo Huang, Dong Chen, 2014, PloS one.

Design, synthesis, biological evaluation and molecular dynamics studies of 4-thiazolinone derivatives as protein tyrosine phosphatase 1B (PTP1B) inhibitors

Shu-Qing Wang, Runling Wang, Zhihui Zheng, 2020, Journal of biomolecular structure & dynamics.

Design, Synthesis, Biological Activity and Molecular Dynamics Studies of Specific Protein Tyrosine Phosphatase 1B Inhibitors over SHP-2

Xiaobo Li, Shu-Qing Wang, Runling Wang, 2013, International journal of molecular sciences.

Effects of Smilaxchinoside A and Smilaxchinoside C, Two Steroidal Glycosides from Smilax riparia, on Hyperuricemia in a Mouse Model

Chong-Zhi Wang, C. Yuan, Shu-Qing Wang, 2014, Phytotherapy research : PTR.

Phytochemical and chemotaxonomic study on the rhizomes of Smilax riparia (Liliaceae)

Shu-Qing Wang, Xiao-hui Wu, Yan-Wen Zhang, 2018 .

Anti-hyperuricemia effects of allopurinol are improved by Smilax riparia, a traditional Chinese herbal medicine.

Chong-Zhi Wang, C. Yuan, Shu-Qing Wang, 2015, Journal of ethnopharmacology.

Riparoside B and timosaponin J, two steroidal glycosides from Smilax riparia, resist to hyperuricemia based on URAT1 in hyperuricemic mice.

Shu-Qing Wang, Xiao-hui Wu, Jun Zhang, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Ethyl 4-[(4-chlorophenoxy)methyl]-2-(4-nitrophenyl)-1,3-thiazole-5-carboxylate

Shu-Qing Wang, Runling Wang, Wei-Li Dong, 2011, Acta crystallographica. Section E, Structure reports online.

Three new powerful oseltamivir derivatives for inhibiting the neuraminidase of influenza virus.

Kuo-Chen Chou, Xian-Chao Cheng, Run-Ling Wang, 2010, Biochemical and biophysical research communications.

Design of specific inhibitors of the protein tyrosine phosphatase SHP-2 by virtual screening and core hopping method

Shu-Qing Wang, Wei-Ren Xu, Runling Wang, 2014 .

Identification of novel multitargeted PPARα/γ/δ pan agonists by core hopping of rosiglitazone

Jun Zhang, Wei-Ren Xu, Xian-Chao Cheng, 2014, Drug design, development and therapy.

Computational 3D structures of drug-targeting proteins in the 2009-H1N1 influenza A virus

K. Chou, Q. Du, Shu-Qing Wang, 2010 .

Pallidifloside D from Smilax riparia enhanced allopurinol effects in hyperuricemia mice.

Fei Yu, Shu-Qing Wang, Xiao-hui Wu, 2015, Fitoterapia.

Hypouricemic effect of allopurinol are improved by Pallidifloside D based on the uric acid metabolism enzymes PRPS, HGPRT and PRPPAT.

Shu-Qing Wang, Xi Zhang, Xiao-hui Wu, 2016, Fitoterapia.

Structure-Based and Multiple Potential Three-Dimensional Quantitative Structure-Activity Relationship (SB-MP-3D-QSAR) for Inhibitor Design

Jing Gao, Qishi Du, Ri-Bo Huang, 2012, J. Chem. Inf. Model..

Identification of dual ligands targeting angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ by core hopping of telmisartan

Jun Zhang, Wei-Ren Xu, Xian-Chao Cheng, 2017, Journal of biomolecular structure & dynamics.

Analogue inhibitors by modifying oseltamivir based on the crystal neuraminidase structure for treating drug-resistant H5N1 virus.

Kuo-Chen Chou, Qi-Shi Du, K. Chou, 2007, Biochemical and biophysical research communications.

Agonist and antagonist recognition studies for oestrogen receptor by molecular dynamics simulation

Xiaobo Li, Shu-Qing Wang, Runling Wang, 2013 .

Molecular modeling and chemical modification for finding peptide inhibitor against severe acute respiratory syndrome coronavirus main proteinase

Kuo-Chen Chou, Qishi Du, Dongqing Wei, 2004, Analytical Biochemistry.

Polyprotein cleavage mechanism of SARS CoV Mpro and chemical modification of the octapeptide

K. Chou, Dongqing Wei, Hong Guo, 2004, Peptides.

Cyclopeptides design as blockers against HCV p7 channel in silico

J. Wang, Shu-Qing Wang, Shichao Pang, 2019, Molecular Simulation.

Pallidifloside D from Smilax riparia enhanced allopurinol effects in hyperuricemia mice.

Fei Yu, Shu-Qing Wang, Xiao-hui Wu, 2015, Fitoterapia.

Identification of novel multitargeted PPAR α / γ / δ pan agonists by core hopping of rosiglitazone

Shu-Qing Wang, Wei-Ren Xu, Jun Zhang, 2014 .

Identification of dual ligands targeting angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ by core hopping of telmisartan

Shu-Qing Wang, Wei-Ren Xu, Runling Wang, 2017, Journal of biomolecular structure & dynamics.

Simulated Protein Thermal Detection (SPTD) for Enzyme Thermostability Study and an Application Example for Pullulanase from Bacillus deramificans.

Kuo-Chen Chou, Jian-Zong Meng, Ri-Bo Huang, 2019, Current pharmaceutical design.