O. Moradei

发表

Substituted N-(2-aminophenyl)-benzamides, (E)-N-(2-aminophenyl)-acrylamides and their analogues: novel classes of histone deacetylase inhibitors.

A. Kalita, A. Macleod, O. Moradei, 2006, Bioorganic & medicinal chemistry letters.

4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors.

A. Kalita, M. Robert, O. Moradei, 2008, Bioorganic & medicinal chemistry letters.

Histone deacetylase inhibitors in cancer therapy: new compounds and clinical update of benzamide-type agents.

R. Martell, O. Moradei, A. Vaisburg, 2008, Current topics in medicinal chemistry.

MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo

Sylvain Lefebvre, Daniel Delorme, A. Kalita, 2008, Molecular Cancer Therapeutics.

Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors.

Daniel Delorme, A. Kalita, M. Robert, 2003, Journal of medicinal chemistry.

N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors.

M. Robert, A. Macleod, O. Moradei, 2007, Bioorganic & medicinal chemistry letters.

Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity.

O. Moradei, S. Leit, S. Fréchette, 2007, Journal of medicinal chemistry.

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.

Tim J. Wigle, K. Swinger, T. Riera, 2015, ACS medicinal chemistry letters.

Synthesis of Furanose Glycosides of Abequose (3, 6-Dideoxy-D-Xylo-Hexose)

O. Moradei, R. Lederkremer, O. Varela, 1991 .

Catalytic Hydrogenation of Phosphate Enol Esters Present in Branched Chain Dienepyranosides in a Route to Thromboxane Analogs from D-Galactose

O. Moradei, A. Cirelli, J. Thiem, 1999 .

SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide (MGCD0103).

A. Kalita, O. Moradei, S. Leit, 2009, Bioorganic & medicinal chemistry letters.

Histone deacetylase inhibitors: latest developments, trends and prospects.

C. Maroun, O. Moradei, I. Paquin, 2005, Current medicinal chemistry. Anti-cancer agents.

Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma

T. Riera, Lei Jin, R. Copeland, 2017, Scientific Reports.

Simple Stereocontrolled Synthesis of Methyl 2-Deoxy-d-erythro-hexopyranosid-4-uloses, Thromboxane B2 (TXB2) Precursors, from d-Galactose

O. Moradei, A. Cirelli, J. Thiem, 1995 .

Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.

W. Shipe, H. Su, J. Gesell, 2016, ACS medicinal chemistry letters.

Total asymmetric synthesis of the putative structure of the cytotoxic diterpenoid (-)-sclerophytin a and of the authentic natural sclerophytins A and B.

D. Friedrich, B. Dyck, O. Moradei, 2001, Journal of the American Chemical Society.

(5S)-(D-menthyloxy)-2(5H)-furanone

O. Moradei, L. Paquette, 2003 .

Synthesis of Thromboxane A2 Models from Glucose. II. Epoxidation Studies of Hex-2-enopyranosides

O. Moradei, A. Cirelli, J. Thiem, 1997 .

Synthesis of the alleged structure of sclerophytin A. The setting of two oxygen bridges within the fused cyclodecanol B ring is not Nature's Way.

O. Moradei, L. Paquette, T. Lange, 2000, Organic letters.

ANOMALOUS HORNER-WADSWORTH-EMMONS REACTIONS ON 3,4-ENULOSES.

O. Moradei, A. Cirelli, C. Mortier, 1997 .

Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma

T. Riera, Lei Jin, R. Copeland, 2017, Scientific Reports.

Rapid occurrence of sugar tricyclic orthoesters by acid catalyzed intramolecular orthotransesterification

O. Moradei, A. Cirelli, C. Mortier, 2005 .

(2-Amino-phenyl)-amides of ω-substituted alkanoic acids as new histone deacetylase inhibitors

A. Kalita, A. Macleod, O. Moradei, 2004 .

Discovery of N-(2-aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an orally active histone deacetylase inhibitor.

Isabelle Paquin, Daniel Delorme, A. Kalita, 2008, Journal of medicinal chemistry.

Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors.

Daniel Delorme, O. Moradei, S. Leit, 2002, Journal of medicinal chemistry.

(2-amino-phenyl)-amides of omega-substituted alkanoic acids as new histone deacetylase inhibitors.

A. Kalita, A. Macleod, O. Moradei, 2004, Bioorganic & medicinal chemistry letters.

Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.

Lei Jin, R. Copeland, P. Boriack-Sjodin, 2016, ACS chemical biology.

Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors.

A. Kalita, M. Robert, A. Macleod, 2008, Bioorganic & medicinal chemistry letters.

MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo

A. Kalita, M. Robert, A. Macleod, 2008, Molecular Cancer Therapeutics.