D. Delorme

发表

Substituted N-(2-aminophenyl)-benzamides, (E)-N-(2-aminophenyl)-acrylamides and their analogues: novel classes of histone deacetylase inhibitors.

A. Kalita, A. Macleod, O. Moradei, 2006, Bioorganic & medicinal chemistry letters.

4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors.

A. Kalita, M. Robert, O. Moradei, 2008, Bioorganic & medicinal chemistry letters.

MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo

Sylvain Lefebvre, Daniel Delorme, A. Kalita, 2008, Molecular Cancer Therapeutics.

Journal of Complementary and Integrative Medicine Extract of North American Ginseng ( Panax Quinquefolius ) , Administered to Leukemic , Juvenile Mice Extends their Life Span

D. Delorme, J. Shan, Sandra C. Miller, 2011 .

Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors.

Daniel Delorme, A. Kalita, M. Robert, 2003, Journal of medicinal chemistry.

N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors.

M. Robert, A. Macleod, O. Moradei, 2007, Bioorganic & medicinal chemistry letters.

Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.

Hugo Poirier, D. Delorme, Jing Liu, 2008, Bioorganic & medicinal chemistry.

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors.

Nadine H. Elowe, A. Macleod, A. Vaisburg, 2009, Bioorganic & medicinal chemistry letters.

Linking bisphosphonates to the free amino groups in fluoroquinolones: preparation of osteotropic prodrugs for the prevention of osteomyelitis.

Hugo Poirier, D. Delorme, Jing Liu, 2008, Journal of medicinal chemistry.

Potential Applications of Glycosaminoglycan-Related Compounds in Alzheimer's Disease

B. Greenberg, C. Morissette, D. Delorme, 2007 .

Design and synthesis of a novel class of histone deacetylase inhibitors.

S. Leit, S. Fréchette, G. Bouchain, 2001, Bioorganic & medicinal chemistry letters.

SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide (MGCD0103).

A. Kalita, O. Moradei, S. Leit, 2009, Bioorganic & medicinal chemistry letters.

Comparison of urinary leukotriene E4 and 16-carboxytetranordihydro leukotriene E4 excretion in allergic asthmatics after inhaled antigen.

S. Charleson, A. Ford-hutchinson, P. Tagari, 1990, Eicosanoids.

Substituted coumarins as potent 5-lipoxygenase inhibitors.

J. Falgueyret, D. Riendeau, C. Brideau, 2006, Bioorganic & medicinal chemistry letters.

Mycoplasma arginini TUH-14 membrane lipoproteins induce production of interleukin-1, interleukin-6, and tumor necrosis factor alpha by human monocytes

A. Herbelin, D. Delorme, F. Praz, 1994, Infection and immunity.

Metabolism and excretion of exogenous [3H]-LTC4 in primates.

J. Rokach, P. Tagari, Y. Girard, 1989, Prostaglandins.

N,N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: the development of diaryl amino piperidines as potent delta opioid receptor agonists with in vivo anti-nociceptive activity in rodent models.

D. Delorme, Paul B. Jones, E. Roberts, 2009, Bioorganic & Medicinal Chemistry Letters.

The asymmetric synthesis of α-chloro α-alkyl and α-methyl α-alkyl phosphonic acids of high enantiomeric purity.

S. Hanessian, D. Delorme, Y. Bennani, 1990 .

Additions and Corrections - Design and Reactivity of Topologically Unique, Chiral Phosphonamides. Remarkable Diastereofacial Selectivity in Asymmetric Olefination and Alkylation.

Y. Leblanc, S. Hanessian, D. Delorme, 1984 .

Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC.

Hugo Poirier, D. Delorme, G. McKay, 2006, Bioorganic & medicinal chemistry letters.

Asymmetric synthesis of diarylmethylamines: preparation of selective opioid delta receptor ligands

D. Delorme, E. Roberts, R. Lavoie, 1998 .

N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.

S. Yue, D. Delorme, K Payza, 2000, Journal of medicinal chemistry.

New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.

S. Yue, D. Delorme, H. Gagnon, 2000, Journal of medicinal chemistry.

Stereoselective Hydrogen Transfer Reactions Involving Acyclic Radicals. Tandem Substituted Tetrahydrofuran Formation and Stereoselective Reduction: Synthesis of the C17-C22 Subunit of Ionomycin

C. Yoakim, D. Delorme, A. Slassi, 1994 .

Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability.

J. Falgueyret, D. Riendeau, C. Brideau, 1996, Journal of medicinal chemistry.

Stereoselective rardical-mediated reduction and alkylation of α-halo esters

C. Yoakim, C. Chabot, B. Simoneau, 1991 .

Novel Non‐Nucleobase Inhibitors of Staphylococcus aureus DNA Polymerase IIIC.

Hugo Poirier, D. Delorme, G. McKay, 2006 .

Mild cleavage of methoxymethyl (MOM) ethers with trimethylsilyl bromide

S. Hanessian, D. Delorme, Y. Dufresne, 1984 .

CARBOHYDRATES AS “CHIRAL TEMPLATES” IN ORGANIC SYNTHESIS – TARGET: BOROMYCIN

P. Tyler, S. Hanessian, D. Delorme, 1983 .

SYNTHESIS AND BIOLOGICAL EVALUATION OF BOTH ENANTIOMERS OF L-761,000 AS INHIBITORS OF CYCLOOXYGENASE 1 AND 2

Yves Leblanc, Daniel Guay, Petpiboon Prasit, 1996 .

Mild cleavage of methoxymethyl (MOM) ethers with trimethylsilyl bromide

S. Hanessian, D. Delorme, Y. Dufresne, 1984 .

Female body size, parity, and malaria infection of Anopheles maculatus (Diptera: Culicidae) in peninsular Malaysia.

B. A. Harrison, P. Kittayapong, J. Edman, 1992, Journal of medical entomology.

Total synthesis of the C-3 – C-17 segment of boromycin

P. Tyler, S. Hanessian, D. Delorme, 1983 .

Synthesis of 4-amino-4(S)-dihydrospectinomycin.

R. Roy, S. Hanessian, D. Delorme, 1981, The Journal of antibiotics.

Stereoselective reduction of acyclic α-bromo esters

C. Yoakim, D. Delorme, Y. Guindon, 1990 .

Dietary consumption of Echinacea by mice afflicted with autoimmune (type I) diabetes: Effect of consuming the herb on hemopoietic and immune cell dynamics

D. Delorme, S. C. Miller, 2005, Autoimmunity.

Sulfonamide anilides, a novel class of histone deacetylase inhibitors, are antiproliferative against human tumors.

A. Kalita, A. Macleod, S. Leit, 2002, Cancer research.

(2-Amino-phenyl)-amides of ω-substituted alkanoic acids as new histone deacetylase inhibitors

A. Kalita, A. Macleod, O. Moradei, 2004 .

Genetic characterization of Toxoplasma gondii from wild boar (Sus scrofa) in France.

C. Ducrot, D. Aubert, I. Villena, 2009, Veterinary parasitology.

Discovery of N-(2-aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an orally active histone deacetylase inhibitor.

Isabelle Paquin, Daniel Delorme, A. Kalita, 2008, Journal of medicinal chemistry.

Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors.

Daniel Delorme, O. Moradei, S. Leit, 2002, Journal of medicinal chemistry.

(2-amino-phenyl)-amides of omega-substituted alkanoic acids as new histone deacetylase inhibitors.

A. Kalita, A. Macleod, O. Moradei, 2004, Bioorganic & medicinal chemistry letters.

Journal of Complementary and Integrative Medicine An Extract from North American Ginseng Stimulates Spontaneous Immunity in Infant Mice : Sustained , Augmented Immunity in Adulthood Long after Withdrawal of the Extract

D. Delorme, S. C. Miller, 2011 .

Synthesis of beta-oxidation products as potential leukotriene metabolites and their detection in bile of anesthetized rat.

J. Rokach, Y. Girard, D. Delorme, 1988, Prostaglandins.

SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes.

Nadine H. Elowe, A. Macleod, A. Vaisburg, 2009, Bioorganic & medicinal chemistry letters.

CVT-E002 stimulates the immune system and extends the life span of mice bearing a tumor of viral origin.

D. Delorme, J. Shan, S. C. Miller, 2009, Journal of the Society for Integrative Oncology.

Implantation of acephate and injection of microbial insecticides into pin oaks for control of gypsy moth: time and efficacy comparisons

F. W. Ravlin, S. Fleischer, D. Delorme, 1989 .

Further evidence for a gamma/delta T cell receptor-mediated TCT.1/CD48 recognition.

F. Mami-Chouaib, P. Del Porto, D. Delorme, 1991, Journal of immunology.

Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816.

J. Falgueyret, D. Riendeau, C. Brideau, 1993, Journal of medicinal chemistry.

Marking gypsy moth (Lepidoptera: Lymantriidae) life stages and products with low doses of rubidium injected or implanted into pin oak.

F. W. Ravlin, S. Fleischer, D. Delorme, 1990 .

Novel hydroxamate and anilide derivatives as potent histone deacetylase inhibitors: synthesis and antiproliferative evaluation.

Daniel Delorme, G. Bouchain, D. Delorme, 2003, Current medicinal chemistry.

Total synthesis of LTB4 and analogs

R. Zamboni, D. Delorme, Y. Guindon, 1988 .

Limited T-cell receptor diversity in liver-infiltrating lymphocytes from patients with primary biliary cirrhosis.

S. Roman-Roman, L. Ferradini, S. Meuer, 1993, Journal of Autoimmunity.

A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus.

J. Pelletier, P. Gros, D. Delorme, 2006, Bioorganic & medicinal chemistry.

Metabolism of peptide leukotrienes in the rat.

J. Rokach, Y. Girard, D. Delorme, 1989, Advances in prostaglandin, thromboxane, and leukotriene research.

Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors.

A. Kalita, M. Robert, A. Macleod, 2008, Bioorganic & medicinal chemistry letters.

Myelointegration of titanium implants: B lymphopoiesis and hemopoietic cell proliferation in mouse bone marrow exposed to titanium implants.

P. Branemark, D. Delorme, M. Rahal, 2000, The International journal of oral & maxillofacial implants.

Total synthesis of leukotriene E4 metabolites and precursors to radiolabeled forms of those metabolites

J. Rokach, Y. Girard, D. Delorme, 1989 .

MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo

A. Kalita, M. Robert, A. Macleod, 2008, Molecular Cancer Therapeutics.