Reem K. Arafa

发表

Synthesis and in vitro investigation of novel cytotoxic pyrimidine and pyrazolopyrimidne derivatives showing apoptotic effect.

F. Ragab, Y. M. Nissan, Emad M Seif, 2020, Bioorganic chemistry.

Nourin-Associated miRNAs: Novel Inflammatory Monitoring Markers for Cyclocreatine Phosphate Therapy in Heart Failure

R. Christenson, Reem K. Arafa, D. Kreutzer, 2021, International journal of molecular sciences.

NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

A. Dinkova-Kostova, Reem K. Arafa, Nehal H. Elghazawy, 2016, Drug design, development and therapy.

Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives

A. Dinkova-Kostova, Reem K. Arafa, Nehal H. Elghazawy, 2016, Journal of enzyme inhibition and medicinal chemistry.

Investigating the structure-activity relationship of marine polycyclic batzelladine alkaloids as promising inhibitors for SARS-CoV-2 main protease (Mpro)

A. Elfiky, M. Sobeh, Reem K. Arafa, 2022, Computers in Biology and Medicine.

Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19)

Reem K. Arafa, I. Eissa, T. A. Abd El-Aziz, 2020, Biomolecules.

Cytotoxic activity of some novel sulfonamide derivatives.

Reem K. Arafa, M. Alsaid, M. Ghorab, 2015, Acta poloniae pharmaceutica.

Discovery of a Novel Dibromoquinoline Compound Exhibiting Potent Antifungal and Antivirulence Activity That Targets Metal Ion Homeostasis.

T. Hazbun, M. Seleem, Reem K. Arafa, 2018, ACS infectious diseases.

Antibacterial and anticancer profiling of new benzocaine derivatives: Design, synthesis, and molecular mechanism of action

Heba A. Hassan, Reem K. Arafa, E. S. Nossier, 2022, Archiv der Pharmazie.

On the search for COVID-19 therapeutics: identification of potential SARS-CoV-2 main protease inhibitors by virtual screening, pharmacophore modeling and molecular dynamics

Reem K. Arafa, Afnan Hassan, 2021, Journal of biomolecular structure & dynamics.

Phenolics of Achillea fragrantissima growing in Egypt and its cytotoxic activity

R. O. Bakr, A. M. Al-Abd, Reem K. Arafa, 2014 .

New 1-phthalazinone Scaffold based Compounds: Design, Synthesis, Cytotoxicity and Protein Kinase Inhibition Activity.

Riham F. George, Reem K. Arafa, Nehad E Abo-Elmagd, 2018, Mini-Reviews in Medical Chemistry.

Synthesis, Antiproliferative Activity, Apoptotic Profiling, and In‐silico ADME of New Thienylbenzamidine Derivatives

Reem K. Arafa, E. Abdel‐Latif, M. H. Abdel‐Rhman, 2021, ChemistrySelect.

Synthesis and antiproliferative activity of monocationic arylthiophene derivatives.

S. Al-Shihry, Reem K. Arafa, M. Ismail, 2017, European journal of medicinal chemistry.

Selective VEGFR-2 inhibitors: Synthesis of pyridine derivatives, cytotoxicity and apoptosis induction profiling.

Reem K. Arafa, A. Abdelhaleem, Amira Mansour, 2020, Bioorganic chemistry.

New oxadiazoles with selective-COX-2 and EGFR dual inhibitory activity: Design, synthesis, cytotoxicity evaluation and in silico studies.

Reem K. Arafa, M. Salem, R. Arafa, 2019, European journal of medicinal chemistry.

Discovery of New 1,3,4-Oxadiazoles with Dual Activity Targeting the Cholinergic Pathway as Effective Anti-Alzheimer Agents.

Reem K. Arafa, M. Mahmoud, Alaa F. Bakr, 2022, ACS chemical neuroscience.

New benzenesulfonamide scaffold-based cytotoxic agents: Design, synthesis, cell viability, apoptotic activity and radioactive tracing studies.

Wafaa A. Ahmed, M. A. Motaleb, Y. M. Nissan, 2020, Bioorganic chemistry.

Anticancer, antioxidant activities, and DNA affinity of novel monocationic bithiophenes and analogues

Reem K. Arafa, M. Ismail, M. Youssef, 2014, Drug design, development and therapy.

Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity.

Heba S. A. Elzahabi, Reem K. Arafa, Mohamed S. Nafie, 2021, European journal of medicinal chemistry.

Control of ER-positive breast cancer by ERα expression inhibition, apoptosis induction, cell cycle arrest using semisynthetic isoeugenol derivatives.

Reem K. Arafa, Mohamed S. Nafie, M. Abdel-Rahman, 2021, Chemico-biological interactions.

Synthesis, antimicrobial, and antiproliferative activities of substituted phenylfuranylnicotinamidines

Reem K. Arafa, M. Ismail, M. Youssef, 2016, Drug design, development and therapy.

Marine Brominated Tyrosine Alkaloids as Promising Inhibitors of SARS-CoV-2

Reem K. Arafa, T. A. Abd El-Aziz, J. Stockand, 2021, Molecules.

Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer.

Reem K. Arafa, Mohamed S. Nafie, Nada K. Sedky, 2020, Chemico-biological interactions.

The molecular basis of cytotoxicity of α‐spinasterol from Ganoderma resinaceum: Induction of apoptosis and overexpression of p53 in breast and ovarian cancer cell lines

N. El-Badri, Reem K. Arafa, A. Wahba, 2018, Journal of cellular biochemistry.

Personalized Medicine and Resurrected Hopes for the Management of Alzheimer's Disease: A Modular Approach Based on GSK-3β Inhibitors.

Reem K. Arafa, Nehal H Elghazawy, 2017, Advances in experimental medicine and biology.

Preparation and nanoformulation of new quinolone scaffold‐based anticancer agents: Enhancing solubility for better cellular delivery

I. El-Sherbiny, Reem K. Arafa, Amr Hefnawy, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Visnagin and benzofuran scaffold-based molecules as selective cyclooxygenase-2 inhibitors with anti-inflammatory and analgesic properties: design, synthesis and molecular docking.

Reem K. Arafa, Nada K. Sedky, K. Amin, 2019, Future medicinal chemistry.

In Silico Targeting of Fascin Protein for Cancer Therapy: Benchmarking, Virtual Screening and Molecular Dynamics Approaches

Muhammad I. Ismail, Tamer M. Ibrahim, F. Boeckler, 2023, Molecules.

Cyclocreatine Phosphate: A Novel Bioenergetic/Anti-Inflammatory Drug That Resuscitates Poorly Functioning Hearts and Protects against Development of Heart Failure

Reem K. Arafa, D. Kreutzer, A. F. Mohamed, 2023, Pharmaceuticals.

Investigating the antiviral therapeutic potentialities of marine polycyclic lamellarin pyrrole alkaloids as promising inhibitors for SARS-CoV-2 and Zika main proteases (Mpro).

Reem K. Arafa, A. Alabdullah, A. El‐Demerdash, 2023, Journal of biomolecular structure & dynamics.

New proapoptotic chemotherapeutic agents based on the quinolone-3-carboxamide scaffold acting by VEGFR-2 inhibition

Reem K. Arafa, S. M. Abou-Seri, Nada K. Sedky, 2023, Scientific reports.

Undergraduate laboratory series that employs a complete polymerase chain reaction‐restriction fragment length polymorphism experiment for determination of a single nucleotide polymorphism in CYP2R1 gene

Reem K. Arafa, Nada K. Sedky, Nada K Sedky, 2022, Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology.

Undergraduate laboratory series that employs a complete PCR-RFLP experiment for determination of a SNP in CYP2R1 gene

Reem K. Arafa, Nada K. Sedky, Nada K Sedky, 2022 .

Multi-Phase In Silico Discovery of Potential SARS-CoV-2 RNA-Dependent RNA Polymerase Inhibitors among 3009 Clinical and FDA-Approved Related Drugs

Reem K. Arafa, I. Eissa, A. Belal, 2022, Processes.

Personalized Medicine and Resurrected Hopes for the Management of Alzheimer's Disease: A Modular Approach Based on GSK-3β Inhibitors.

Reem K. Arafa, Nehal H Elghazawy, 2017, Advances in experimental medicine and biology.

Computer-assisted drug discovery of potential natural inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase through a multi-phase in silico approach

Ibrahim M. Ibrahim, Reem K. Arafa, I. Eissa, 2023, Antiviral therapy.

Investigating the antiviral therapeutic potentialities of marine polycyclic lamellarin pyrrole alkaloids as promising inhibitors for SARS-CoV-2 and Zika main proteases (Mpro)

Reem K. Arafa, A. Alabdullah, A. El‐Demerdash, 2023, Journal of biomolecular structure & dynamics.

Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aβ Aggregation for Alzheimer's Disease Therapy.

Reem K. Arafa, Mohamed S. Nafie, Shahid M. Nayeem, 2023, ACS chemical neuroscience.