C. Mallari

发表

Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry.

N. Sigal, D. Auld, M. Adler, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis.

M. Adler, M. Whitlow, C. Mallari, 2018, Bioorganic & medicinal chemistry letters.

A novel P2Y12 adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models

C. Mallari, R. Vergona, W. Dole, 2007, Thrombosis and Haemostasis.

In vitro characterization of CT‐001—a short‐acting factor VIIa with enhanced prohemostatic activity

C. Mallari, T. Hermiston, D. Sim, 2021, Research and practice in thrombosis and haemostasis.

CT-001 is a rapid clearing factor VIIa with enhanced clearance and hemostatic activity for the treatment of acute bleeding in non-hemophilia settings.

C. Mallari, T. Hermiston, D. Sim, 2022, Thrombosis research.

Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia

P. Ellinger, Ji-Yun Kim, Xinquan Wang, 2020, Nature Communications.

Identification and Characterization of a Potent, Selective, and Orally Active Antagonist of the CC Chemokine Receptor-1*

D. Taub, S. Harvey, R. Horuk, 2000, The Journal of Biological Chemistry.

Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo.

A. Schottelius, D. Davey, C. Mallari, 2004, Journal of medicinal chemistry.

An N-terminal fragment of bactericidal/permeability-increasing protein protects against hemodynamic and metabolic derangements in rat Gram-negative sepsis

C. Mallari, W. Steve Ammons, 1996 .

A selective inducible NOS dimerization inhibitor prevents systemic, cardiac, and pulmonary hemodynamic dysfunction in endotoxemic mice.

M. Picard, W. Zapol, C. Mallari, 2003, American journal of physiology. Heart and circulatory physiology.

A Selective Inducible Nitric Oxide Synthase Dimerization Inhibitor Prevents Systemic, Cardiac, and Pulmonary Hemodynamic Dysfunction in Endotoxemic Mice

M. Picard, C. Mallari, J. Parkinson, 2003 .

Role of endogenous nitric oxide in progression of atherosclerosis in apolipoprotein E-deficient mice.

C. Mallari, G. Rubanyi, K. Kauser, 2000, American journal of physiology. Heart and circulatory physiology.

Increased aortic stiffness assessed by pulse wave velocity in apolipoprotein E-deficient mice.

M. Halks-Miller, C. Mallari, R. Vergona, 2000, American journal of physiology. Heart and circulatory physiology.

Differential Inhibition of Inducible T Cell Cytokine Secretion by Potent Iron Chelators

Hong-tao Lu, M. Berger, D. Schilling, 2005, Journal of biomolecular screening.

Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia

P. Ellinger, Ji-Yun Kim, Xinquan Wang, 2020, Nature Communications.

Selective modulation of activated protein C activities by a nonactive site–targeting nanobody library

José A Fernández, C. Mallari, X. Xu, 2023, Blood advances.