M. Morrissey

发表

Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry.

N. Sigal, D. Auld, M. Adler, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.

Hieu T. Do, Meenhard Herlyn, David M. Wilson, 2006, Cancer research.

Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa.

M. Adler, M. Whitlow, M. Morrissey, 2007, Bioorganic & medicinal chemistry.

Thick filter neutrophil chemotaxis performed in the absence of albumin.

C. Smith, M. Morrissey, V. Ganu, 1991, Journal of immunological methods.

Human monocytes respond to leukotriene B4 with a transient increase in cytosolic calcium.

M. Morrissey, M. Jarvis, J. Rediske, 1993, Cellular immunology.

Identification and Characterization of a Potent, Selective, and Orally Active Antagonist of the CC Chemokine Receptor-1*

D. Taub, S. Harvey, R. Horuk, 2000, The Journal of Biological Chemistry.

Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor.

R. Horuk, P. Kretschmer, M. Morrissey, 2000, European journal of pharmacology.

Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process.

Wei Xu, M. Morrissey, I. Islam, 2018, Bioorganic & medicinal chemistry letters.

Platelet activating factor stimulates intracellular calcium transients in human neutrophils: involvement of endogenous 5‐lipoxygenase products

M. Morrissey, J. Quintavalla, J. Rediske, 1992, Journal of leukocyte biology.

Comparison of antagonist and agonist binding to the leukotriene B4 receptor intact human polymorphonuclear neutrophils (PMN).

M. Morrissey, M. Jarvis, M. Sills, 1992, The Journal of pharmacology and experimental therapeutics.

A Non-peptide Functional Antagonist of the CCR1 Chemokine Receptor Is Effective in Rat Heart Transplant Rejection*

C. Weber, A. Krensky, H. Gröne, 2001, The Journal of Biological Chemistry.

CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model.

R. Horuk, M. Morrissey, H. Perez, 2001, Immunology letters.

Synthesis and evaluation of a library of peptidomimetics based upon the β-turn

Wei Zhang, J. Ellman, M. Morrissey, 1997 .

Influence of standard and novel LTB4 analogs on human neutrophil chemotaxis measured by the multiwell cap assay.

M. Morrissey, S. Psychoyos, S. Uziel-Fusi, 1989, Journal of immunological methods.

Polymer supported bases in solution-phase synthesis. 2. A convenient method for N-alkylation reactions of weakly acidic heterocycles.

M. Morrissey, R. Mohan, W. Xu, 1998, Bioorganic & medicinal chemistry letters.

Solid-phase synthesis of naphthylamidines as factor VIIa/tissue factor inhibitors.

M. Morrissey, M. McCarrick, D. Light, 2005, Bioorganic & medicinal chemistry letters.

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme factor Xa.

M. Whitlow, D. Davey, K. Eagen, 1998, Journal of medicinal chemistry.

Structure-activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors.

D. Davey, K. Eagen, M. Morrissey, 2003, Bioorganic & medicinal chemistry letters.

Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor XA inhibitors.

M. Morrissey, B. Buckman, R. Mohan, 1998, Bioorganic & medicinal chemistry letters.

Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

Bin Ye, David Light, Marc Adler, 2007, Journal of medicinal chemistry.

Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xa inhibitors.

A. Beatty, M. Whitlow, D. Davey, 1999, Journal of medicinal chemistry.

High capacity screening of pooled compounds: Identification of the active compound without re‐assay of pool members

Richard Spann, Wei Zheng, Jason Kondracki, 1996 .

Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.

M. Whitlow, D. Davey, M. Morrissey, 1999, Acta crystallographica. Section D, Biological crystallography.

Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors.

M. Whitlow, M. Morrissey, S. Sakata, 2000, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological activity of novel factor Xa inhibitors: 4-aryloxy substituents of 2,6-diphenoxypyridines.

K. Eagen, M. Morrissey, G. Phillips, 2002, Bioorganic & medicinal chemistry.

Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors.

M. Morrissey, B. Buckman, R. Mohan, 1998, Bioorganic & medicinal chemistry letters.

Rhodium(I)-catalyzed hydrogenation of olefins. The documentation of hydroxyl-directed stereochemical control in cyclic and acyclic systems

Davidr . Evans, M. Morrissey, D. A. Evans, 1984 .

Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors.

M. Whitlow, M. Morrissey, M. McCarrick, 1999, Journal of medicinal chemistry.

Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors.

M. Morrissey, B. Buckman, R. Mohan, 1998, Bioorganic & medicinal chemistry letters.

Asymmetric oxygenation of chiral imide enolates. A general approach to the synthesis of enantiomerically pure .alpha.-hydroxy carboxylic acid synthons

Davidr . Evans, M. Morrissey, R. L. Dorow, 1985 .

Hydroxyl-directed olefin hydrogenation with iridium catalysts. The documentation of catalyst: substrate stoichiometry as a variable in reaction diastereoselection.

Davidr . Evans, M. Morrissey, 1984 .

(Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa.

M. Morrissey, M. McCarrick, D. Light, 1998, Journal of medicinal chemistry.

Identification and Characterization of Small Molecule Functional Antagonists of the CCR1 Chemokine Receptor*

D. Taub, Wei Zheng, R. Horuk, 1998, The Journal of Biological Chemistry.

Discovery of novel non-peptide CCR1 receptor antagonists.

R. Horuk, M. Morrissey, H. Perez, 1999, Journal of medicinal chemistry.

Discovery of N‐[2‐[5‐[Amino(imino)methyl]‐2‐hydroxyphenoxy]‐3,5‐difluoro‐6‐ [3‐(4,5‐dihydro‐1‐methyl‐1H‐imidazol‐2‐yl)phenoxy]pyridin‐4‐yl] ‐N‐methylglycine (ZK‐807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa.

M. Morrissey, A. L. A. L. E. Et, 1999 .

Polymer supported bases in combinatorial chemistry: Synthesis of aryl ethers from phenols and alkyl halides and aryl halides

M. Morrissey, Raju Mohan, W. Xu, 1997 .

Novel serine-based linker for the solid-phase synthesis of organic compounds

M. Morrissey, Raju Mohan, Y. Chou, 1998 .

Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors.

M. Adler, M. Whitlow, M. Ohlmeyer, 2007, Journal of medicinal chemistry.