J. Hah

发表

Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.

P. Martásek, R. Silverman, L. Roman, 2003, Journal of medicinal chemistry.

1,4-dihydropyrazolo[4,3-d]imidazole phenyl derivatives: a novel type II Raf kinase inhibitors.

J. Hah, T. Sim, Junghun Lee, 2010, Bioorganic & medicinal chemistry letters.

Pharmacophore based 3D-QSAR study of VEGFR-2 inhibitors

Taebo Sim, Seung Joo Cho, F. A. Pasha, 2009, Medicinal Chemistry Research.

De Novo Design and Synthesis of a γ-Turn Peptidomimetic Scaffold and Its Application as JNK3 Allosteric Ligand.

Mi-hyun Kim, J. Hah, Junghun Lee, 2015, Chemistry, an Asian journal.

A Perspective on the Development of c-Jun N-terminal Kinase Inhibitors as Therapeutics for Alzheimer’s Disease: Investigating Structure through Docking Studies

J. Hah, Hyunwook Cho, 2021, Biomedicines.

Light-mediated liberation of enzymatic activity: "small molecule" caged protein equivalents.

D. Lawrence, Haishan Li, J. Hah, 2008, Journal of the American Chemical Society.

Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells.

Mi-hyun Kim, J. Hah, T. Sim, 2011, Bioorganic & medicinal chemistry.

Syntheses of phenylpyrazolodiazepin-7-ones as conformationally rigid analogs of aminopyrazole amide scaffold and their antiproliferative effects on cancer cells.

J. Hah, Han Yu, Minjung Kim, 2011, Bioorganic & medicinal chemistry.

Click approach to the discovery of 1,2,3-triazolylsalicylamides as potent Aurora kinase inhibitors.

J. Hah, W. Aman, J. Ryu, 2014, Bioorganic & medicinal chemistry.

Syntheses and biological evaluation of 1-heteroaryl-2-aryl-1H-benzimidazole derivatives as c-Jun N-terminal kinase inhibitors with neuroprotective effects.

Mi-hyun Kim, J. Hah, Mi-hyun Kim, 2013, Bioorganic & medicinal chemistry.

Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.

P. Martásek, R. Silverman, P. Martásek, 2001, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors.

J. Hah, W. Aman, Junghun Lee, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of aminoquinazoline derivatives and their antiproliferative activities against melanoma cell line.

S. Cho, J. Hah, T. Sim, 2010, Bioorganic & medicinal chemistry letters.

Aminoquinoline derivatives with antiproliferative activity against melanoma cell line.

S. Cho, J. Hah, T. Sim, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and Antiproliferative Activity of Pyridinylcarbonylpyrimidines Against Melanoma Cell Line

J. Hah, T. Sim, C. Oh, 2011 .

The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride

H. Choi, J. Hah, T. Sim, 2010 .

Discovery of 5-methyl-N-(2-arylquinazolin-7-yl)isoxazole-4-carboxamide analogues as highly selective FLT3 inhibitors

J. Hah, Hyungwoo Moon, Miyoung Jang, 2020, Journal of enzyme inhibition and medicinal chemistry.

Rational design and synthesis of 2-(1H-indazol-6-yl)-1H-benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants

J. Hah, Dahyun Kang, Haejin Kim, 2022, Journal of enzyme inhibition and medicinal chemistry.

Conformational restriction of a type II FMS inhibitor leading to discovery of 5-methyl-N-(2-aryl-1H-benzo[d]imidazo-5-yl)isoxazole-4-carboxamide analogues as selective FLT3 inhibitors

J. Hah, Hyungwoo Moon, Miyoung Jang, 2019, Journal of enzyme inhibition and medicinal chemistry.

Discovery of a Potent and Selective JNK3 Inhibitor with Neuroprotective Effect Against Amyloid β-Induced Neurotoxicity in Primary Rat Neurons

J. Hah, Hyunwook Cho, Hyejin Kim, 2021, International journal of molecular sciences.

Discovery of 1-Pyrimidinyl-2-Aryl-4,6-Dihydropyrrolo [3,4-d]Imidazole-5(1H)-Carboxamide as a Novel JNK Inhibitor

J. Hah, Hyunwook Cho, Hyungwoo Moon, 2020, International journal of molecular sciences.

Discovery of 3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives as a novel selective inhibitor scaffold of JNK3

J. Hah, Hyunwook Cho, Hyungwoo Moon, 2019, Journal of enzyme inhibition and medicinal chemistry.

Discovery of novel imidazole chemotypes as isoform-selective JNK3 inhibitors for the treatment of Alzheimer's disease.

Hyuntae Kim, J. Hah, Junghun Lee, 2022, European journal of medicinal chemistry.

Synthesis of stereochemically diverse cyclic analogs of tubulysins.

Sang Kook Lee, J. Hah, S. Y. Bae, 2015, Bioorganic & medicinal chemistry.

Discovery of 4-arylamido 3-methyl isoxazole derivatives as novel FMS kinase inhibitors.

J. Hah, W. Aman, K. Jung, 2015, European journal of medicinal chemistry.

Design and Synthesis of a Novel PLK1 Inhibitor Scaffold Using a Hybridized 3D-QSAR Model

J. Hah, Hyunwook Cho, Hyejin Kim, 2021, International journal of molecular sciences.

Novel 1,4,5,6-tetrahydrocyclopenta[d]imidazole-5-carboxamide-based JNK3 inhibitors: Design, synthesis, molecular docking, and therapeutic potential in neurodegenerative diseases.

J. Hah, Hyejin Kim, Dahyun Kang, 2022, European journal of medicinal chemistry.

Design of Novel IRAK4 Inhibitors Using Molecular Docking, Dynamics Simulation and 3D-QSAR Studies

J. Hah, Wei-ying He, S. Bhujbal, 2022, Molecules.

Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomers

H. Choi, J. Hah, T. Sim, 2012 .

Chemistry-oriented synthesis (ChOS) and target deconvolution on neuroprotective effect of a novel scaffold, oxaza spiroquinone.

S. Kim, Mi-hyun Kim, J. Hah, 2019, European journal of medicinal chemistry.

An efficient and enantioselective total synthesis of naturally occurring L-783277

H. Choi, J. Hah, T. Sim, 2010 .

Enhanced solubility and bioavailability of flurbiprofen by cycloamylose

So Young Kwon, H. Baek, Han‐Gon Choi, 2011, Archives of pharmacal research.

Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.

J. Hah, T. Sim, M. El-Gamal, 2009, Bioorganic & medicinal chemistry letters.

Nec‐1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice

Jung-Mi Hah, J. Hah, Sejin Lee, 2016, EMBO molecular medicine.

Discovery of highly selective CRAF inhibitors, 3-carboxamido-2H-indazole-6-arylamide: In silico FBLD design, synthesis and evaluation.

J. Hah, W. Aman, Junghun Lee, 2016, Bioorganic & medicinal chemistry letters.

Discovery and initial SAR of pyrimidin-4-yl-1H-imidazole derivatives with antiproliferative activity against melanoma cell lines.

J. Hah, T. Sim, C. Oh, 2010, Bioorganic & medicinal chemistry letters.

In silico Ligand-Based (LB) and Docking-Based (DB) 3D-QSAR Study of Potent Chk2 Inhibitors

Taebo Sim, Seung Joo Cho, Muhammad Muddassar, 2007, 2007 Frontiers in the Convergence of Bioscience and Information Technologies.

Novel scaffold evolution through combinatorial 3D-QSAR model studies of two types of JNK3 inhibitors.

J. Hah, W. Aman, Hoyong Jung, 2017, Bioorganic & medicinal chemistry letters.

Design and Synthesis of Aminopyrimidinyl Pyrazole Analogs as PLK1 Inhibitors Using Hybrid 3D-QSAR and Molecular Docking

J. Hah, Hyejin Kim, H. Bae, 2022, Pharmaceuticals.

New diarylureas and diarylamides possessing acet(benz)amidophenyl scaffold: design, synthesis, and antiproliferative activity against melanoma cell line.

J. Hah, T. Sim, M. El-Gamal, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and antiproliferative activity of pyrrolo[3,2-b]pyridine derivatives against melanoma.

J. Hah, T. Sim, J. Choi, 2010, Bioorganic & medicinal chemistry letters.

Deuterium isotope effects and product studies for the oxidation of N(ω)-allyl-L-arginine and N(ω)-allyl-N(ω)-hydroxy-L-arginine by neuronal nitric oxide synthase

R. Silverman, L. Roman, J. Hah, 2000 .

3D-QSAR studies of 1,2-diaryl-1H-benzimidazole derivatives as JNK3 inhibitors with protective effects in neuronal cells.

Mi-hyun Kim, J. Hah, J. Ryu, 2013, Bioorganic & medicinal chemistry letters.

Hologram and Receptor-Guided 3D QSAR Analysis of Anilinobipyridine JNK3 Inhibitors

J. Hah, A. Cho, J. Chung, 2009 .

Discovery of novel 4-aryl-thieno[1,4]diazepin-2-one derivatives targeting multiple protein kinases as anticancer agents.

J. Hah, W. Aman, Junghun Lee, 2018, Bioorganic & medicinal chemistry.

Generation of Non-Nucleotide CD73 Inhibitors Using a Molecular Docking and 3D-QSAR Approach

J. Hah, S. Bhujbal, Swapnil P. Bhujbal, 2021, International journal of molecular sciences.

Correlation between Performance of QM/MM Docking and Simple Classification of Binding Sites

Jae Yoon Chung, Art E. Cho, Jung-Mi Hah, 2009, J. Chem. Inf. Model..

Design, synthesis, and in vitro evaluation of N-(3-(3-alkyl-1H-pyrazol-5-yl) phenyl)-aryl amide for selective RAF inhibition.

J. Hah, Hyungwoo Moon, Daseul Im, 2019, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of 1-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)-1,2,3-triazoles as transforming growth factor-β type 1 receptor kinase inhibitors.

J. Hah, J. Ryu, Yunjeong Park, 2013, Bioorganic & medicinal chemistry letters.

Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as highly selective and potent BRAFV600E and CRAF inhibitor

J. Hah, W. Aman, Hyungwoo Moon, 2019, Journal of enzyme inhibition and medicinal chemistry.

An Intriguing Purview on the Design of Macrocyclic Inhibitors for Unexplored Protein Kinases through Their Binding Site Comparison

J. Hah, Swapnil P. Bhujbal, 2023, Pharmaceuticals.

Acquisition of a "Group A"-selective Src kinase inhibitor via a global targeting strategy.

David S Lawrence, Jung-Mi Hah, D. Lawrence, 2006, Journal of the American Chemical Society.

Mechanism of nitric oxide synthase. Evidence that direct hydrogen atom abstraction from the O-H bond of NG-hydroxyarginine is not relevant to the mechanism.

R. Silverman, J. Hah, H. Huang, 2001, Journal of the American Chemical Society.

Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase

T. Poulos, Huiying Li, R. Silverman, 2004, Nature Structural &Molecular Biology.

In silico binding free energy predictability with π-π interaction energy-augmented scoring function: benzimidazole Raf inhibitors as a case study.

Seung Joo Cho, Jung-Mi Hah, S. Cho, 2012, Bioorganic & medicinal chemistry letters.

Carbamate JNK3 Inhibitors Show Promise as Effective Treatments for Alzheimer's Disease: In Vivo Studies on Mouse Models.

Hyuntae Kim, Soyeon Ahn, J. Hah, 2023, Journal of medicinal chemistry.

QM/MM based 3D QSAR models for potent B-Raf inhibitors

Jae Yoon Chung, Seung Joo Cho, Hwan Won Chung, 2010, J. Comput. Aided Mol. Des..

An Innovative Approach to Address Neurodegenerative Diseases through Kinase-Targeted Therapies: Potential for Designing Covalent Inhibitors

J. Hah, Swapnil P. Bhujbal, 2023, Pharmaceuticals.

Light-mediated liberation of enzymatic activity: "small molecule" caged protein equivalents.

D. Lawrence, Haishan Li, J. Hah, 2008, Journal of the American Chemical Society.

Gaining Insights into Key Structural Hotspots within the Allosteric Binding Pockets of Protein Kinases

J. Hah, Joonhong Jun, Swapnil P. Bhujbal, 2024, International Journal of Molecular Sciences.