S. Di Marco

发表

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor.

R. De Francesco, A. Vannini, P. Gallinari, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8–substrate complex

R. De Francesco, A. Vannini, A. Carfi, 2007, EMBO reports.

Crystal Structure of the Quorum-sensing Protein TraM and Its Interaction with the Transcriptional Regulator TraR*

A. Vannini, C. Volpari, S. Di Marco, 2004, Journal of Biological Chemistry.

Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase.

U. Koch, R. De Francesco, P. Baiocco, 2011, Journal of medicinal chemistry.

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Nguyen H. Tran, Vidyashankara G. Iyer, Andreas C. Themistocleous, 2020, Lancet.

Determination of the stoichiometry of noncovalent complexes using reverse-phase high-performance liquid chromatography coupled with electrospray ion trap mass spectrometry.

A. Vannini, Laura Orsatti, F. Bonelli, 2002, Analytical biochemistry.

The design and enzyme-bound crystal structure of indoline based peptidomimetic inhibitors of hepatitis C virus NS3 protease.

S. Harper, U. Koch, V. Matassa, 2004, Journal of medicinal chemistry.

Interaction of nitric oxide with ceruloplasmin lacking an EPR-detectable type 2 copper.

S. Di Marco, M. C. Bonaccorsi di Patti, G. Musci, 1991, Biochemistry.

Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions.

Juliana K. Wambua, J. McCarthy, J. Vekemans, 2017, JCI insight.

Crystallization and preliminary X-ray diffraction studies of the quorum-sensing regulator TraM from Agrobacterium tumefaciens.

A. Vannini, C. Volpari, S. Di Marco, 2004, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X-ray diffraction studies of the transcriptional regulator TraR bound to its cofactor and to a specific DNA sequence.

C. Gargioli, R. De Francesco, A. Vannini, 2002, Acta crystallographica. Section D, Biological crystallography.

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Nguyen H. Tran, Vidyashankara G. Iyer, Andreas C. Themistocleous, 2021, The Lancet.

Studies on the Mode of Ku Interaction with DNA*

G. Baldini, D. Arosio, A. Vindigni, 2002, The Journal of Biological Chemistry.

Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors.

E. H. Rydberg, U. Koch, R. De Francesco, 2009, Journal of medicinal chemistry.

Recombinant soluble beta-1,4-galactosyltransferases expressed in Saccharomyces cerevisiae. Purification, characterization and comparison with human enzyme.

U. Kragl, E. Berger, C. Wandrey, 1996, European journal of biochemistry.

A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH

R. Cortese, P. Kaye, Deborah F. Smith, 2017, PLoS neglected tropical diseases.

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.

Nguyen H. Tran, Andreas C. Themistocleous, David J. Smith, 2020, Lancet.

Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.

Michael Rowley, Frank Narjes, Giovanni Migliaccio, 2005, Journal of medicinal chemistry.

The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA

R. Cortese, C. Gargioli, R. De Francesco, 2002, The EMBO journal.

Chimpanzee adenovirus– and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults

Andrew J. Pollard, A. Folgori, R. Cortese, 2015, Science Translational Medicine.

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA.

Edward Wright, Thomas Strecker, Paul Chaplin, 2015, The New England journal of medicine.

Multiple determinants influence complex formation of the hepatitis C virus NS3 protease domain with its NS4A cofactor peptide.

A. Urbani, R. De Francesco, P. Pucci, 1999, Biochemistry.

Nucleic acid binding of the RTN1-C C-terminal region: toward the functional role of a reticulon protein.

M. Paci, S. Melino, S. Di Marco, 2009, Biochemistry.

Structure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone*

M. Grütter, P. Mittl, J. Priestle, 1997, The Journal of Biological Chemistry.

Oligomerization of Sulfolobus solfataricus signature amidase is promoted by acidic pH and high temperature.

R. Casadio, R. Chiaraluce, V. Consalvi, 2005, Archaea.

Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.

J. Priestle, S. D. Marco, S. Di Marco, 1997, Structure.

A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex.

M. Grütter, P. Mittl, G. Fendrich, 1997, Structure.

The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.

G Bricogne, G. Sheldrick, G. Bricogne, 1999, Structure.

Cyclic nucleotide phosphodiesterase activity in stem cells of human periodontal ligament (PDL-MSCs) before and after osteogenic induction.

G. Spoto, O. Trubiani, S. Di Marco, 2013, Oral surgery, oral medicine, oral pathology and oral radiology.

A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S]

Lora Hamuro, Jayne Chin, L. Mitnaul, 2011, Journal of Lipid Research.

A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9) C-terminal Domain Antibody Antigen-binding Fragment Inhibits PCSK9 Internalization and Restores Low Density Lipoprotein Uptake

J. Condra, M. Bottomley, R. Cummings, 2010, The Journal of Biological Chemistry.

Design of selective eglin inhibitors of HCV NS3 proteinase.

R. De Francesco, C. Steinkühler, C. Volpari, 1998, Biochemistry.

Synovial type (group II) phospholipase A2 in cartilage.

A. Schmitz, M. Grütter, T. Nevalainen, 1993, The Journal of rheumatology.

Purification, analysis, and enzymatic activity of recombinant human synovial fluid phospholipase A2 and N-terminal variants.

A. Schmitz, M. Grütter, J. van Oostrum, 1992, Journal of biochemistry.

Adenovirus DNA Polymerase Loses Fidelity on a Stretch of Eleven Homocytidines during Pre-GMP Vaccine Preparation

T. Hanke, S. Di Marco, S. Colloca, 2022, Vaccines.

Inhibition of the Hepatitis C Virus NS3/4A Protease

R. De Francesco, M. Rizzi, F. Narjes, 2000, The Journal of Biological Chemistry.

Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small Molecule Inhibitors Bound to a Novel Allosteric Site*

Uwe Koch, Michael Rowley, Frank Narjes, 2005, Journal of Biological Chemistry.

Engineering, characterization and phage display of hepatitis C virus NS3 protease and NS4A cofactor peptide as a single-chain protein.

R. Cortese, A. Pasquo, C. Steinkühler, 1998, Protein engineering.