S. Loverix

发表

DFT-based ranking of zinc-binding groups in histone deacetylase inhibitors.

P. Geerlings, K. Vanommeslaeghe, D. Tourwé, 2005, Bioorganic & medicinal chemistry.

Theoretical study revealing the functioning of a novel combination of catalytic motifs in histone deacetylase.

P. Geerlings, F. De Proft, K. Vanommeslaeghe, 2005, Bioorganic & medicinal chemistry.

Species-Specific Determinants in the IgG CH3 Domain Enable Fab-Arm Exchange by Affecting the Noncovalent CH3–CH3 Interaction Strength

P. Parren, I. Lasters, A. Heck, 2011, The Journal of Immunology.

Influence of Stacking on the Hydrogen Bond Donating Potential of Nucleic Bases.

P. Geerlings, K. Vanommeslaeghe, P. Mignon, 2006, Journal of chemical theory and computation.

Quantitative analysis of the interaction strength and dynamics of human IgG4 half molecules by native mass spectrometry.

P. Parren, I. Lasters, A. Heck, 2011, Structure.

Functional assessment of “in vivo” and “in silico” mutations in the guanine binding site of RNase T1: A DFT study

J. Steyaert, P. Geerlings, P. Mignon, 2004 .

A Nucleophile Activation Dyad in Ribonucleases

J. Steyaert, P. Geerlings, R. Loris, 2002, The Journal of Biological Chemistry.

Reviving old protecting group chemistry for site-selective peptide-protein conjugation.

I. Lasters, Mathias Laga, J. Gettemans, 2018, Chemical communications.

Quantum chemical study of leaving group activation in T. vivax nucleoside hydrolase

J. Steyaert, P. Geerlings, W. Versées, 2006 .

Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting

I. Lasters, J. Desmet, S. Savvides, 2021, Science Advances.

Influence of the π–π interaction on the hydrogen bonding capacity of stacked DNA/RNA bases

J. Steyaert, P. Geerlings, P. Mignon, 2005, Nucleic acids research.

Mechanism of RNase T1: concerted triester-like phosphoryl transfer via a catalytic three-centered hydrogen bond.

J. Steyaert, R. Strömberg, S. Loverix, 2000, Chemistry & biology.

Influence of Stacking on Hydrogen Bonding: Quantum Chemical Study on Pyridine-Benzene Model Complexes

Paul Geerlings, Frank De Proft, Pierre Mignon, 2004 .

Substrate-assisted Leaving Group Activation in Enzyme-catalyzed N-Glycosidic Bond Cleavage*

J. Steyaert, P. Geerlings, W. Versées, 2005, Journal of Biological Chemistry.

Leaving group activation by aromatic stacking: an alternative to general acid catalysis.

Paul Geerlings, Jan Steyaert, J. Steyaert, 2004, Journal of molecular biology.

Structural basis of IL-23 antagonism by an Alphabody protein scaffold

I. Lasters, J. Desmet, S. Savvides, 2014, Nature Communications.

Deciphering the mechanism of RNase T1.

J. Steyaert, S. Loverix, 2001, Methods in enzymology.

The Activation of Electrophile, Nucleophile and Leaving Group during the Reaction Catalysed by pI258 Arsenate Reductase

Goedele Roos, Lode Wyns, Paul Geerlings, 2006, Chembiochem : a European journal of chemical biology.

An engineered ribonuclease preferring phosphorothioate RNA

J. Steyaert, R. Strömberg, S. Loverix, 1998, Nature Structural Biology.

A Computational and Conceptual DFT Study on the Michaelis Complex of pI258 Arsenate Reductase. Structural Aspects and Activation of the Electrophile and Nucleophile

Goedele Roos, Lode Wyns, Paul Geerlings, 2004 .

Interplay between π–π interactions and the H-bonding ability of aromatic nitrogen bases

P. Geerlings, P. Mignon, S. Loverix, 2005 .

CH3 - Affecting the Noncovalent CH3 CH3 Domain Enable Fab-Arm Exchange by Species-Specific Determinants in the IgG

P. Parren, I. Lasters, A. Heck, 2011 .

A Computational and Conceptual DFT Study of the Reactivity of Anionic Compounds: Implications for Enzymatic Catalysis

Goedele Roos, Paul Geerlings, P. Geerlings, 2003 .

Additivity of Protein-Guanine Interactions in Ribonuclease T1*

J. Steyaert, S. Loverix, Jan Doumen, 1997, The Journal of Biological Chemistry.

Non-immunized natural human heavy chain CDR3 repertoires allow the isolation of high affinity peptides mimicking a human influenza hemagglutinin epitope.

I. Lasters, N. Boutonnet, H. de Haard, 2008, Molecular immunology.

Reconsidering the energetics of ribonuclease catalysed RNA hydrolysis.

L. Wyns, J. Steyaert, J. Martins, 1998, European journal of biochemistry.