F. Ausseil

发表

Design, Synthesis and Biological Evaluation of 4-Amino-N-(4-aminophenyl)benzamide Analogues of Quinoline-Based SGI-1027 as Inhibitors of DNA Methylation

F. Sautel, A. Jeltsch, P. Arimondo, 2014, ChemMedChem.

Preparation of phenylethylbenzamide derivatives as modulators of DNMT3 activity

M. Szyf, P. Arimondo, Y. St-Pierre, 2013 .

Properly Substituted Analogues of BIX-01294 Lose Inhibition of G9a Histone Methyltransferase and Gain Selective Anti-DNA Methyltransferase 3A Activity

E. Novellino, A. Mai, Xiaodong Cheng, 2014, PloS one.

Development of a CERT START Domain–Ceramide HTRF Binding Assay and Application to Pharmacological Studies and Screening

F. Ausseil, Céline Faux, L. Fleury, 2015, Journal of biomolecular screening.

DNA methylation inhibitors in cancer: recent and future approaches.

Jean-Marc Gregoire, Christina Gros, P. Arimondo, 2012, Biochimie.

Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer

B. Ducommun, P. Cordelier, F. Ausseil, 2012, BMC Cancer.

High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources

C. Bailly, L. Créancier, A. Kruczynski, 2007, Journal of biomolecular screening.

The CERT antagonist HPA-12: first practical synthesis and individual binding evaluation of the four stereoisomers.

F. Ausseil, L. Fleury, C. Santos, 2015, Bioorganic & medicinal chemistry.

Physalin B, a novel inhibitor of the ubiquitin-proteasome pathway, triggers NOXA-associated apoptosis.

J. Annereau, C. Bailly, L. Créancier, 2008, Biochemical pharmacology.

Proteasome inhibitors from Neoboutonia melleri.

F. Sautel, L. Marcourt, L. Vendier, 2012, Journal of natural products.

Alisiaquinones and alisiaquinol, dual inhibitors of Plasmodium falciparum enzyme targets from a New Caledonian deep water sponge.

L. Marcourt, S. Chevalley, F. Ausseil, 2008, Journal of natural products.

Heteronemin as a Protein Farnesyl Transferase Inhibitor

B. Hill, F. Ausseil, C. Debitus, 2004 .

New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors*

A. Mai, L. Mourey, M. Bouhlel, 2014, The Journal of Biological Chemistry.

Semisynthetic neoboutomellerone derivatives as ubiquitin-proteasome pathway inhibitors.

F. Sautel, L. Marcourt, P. Arimondo, 2012, Bioorganic & medicinal chemistry.

Bioactive flavonoids of Tanacetum parthenium revisited.

F. Ausseil, B. David, G. Massiot, 2003, Phytochemistry.

Design and synthesis of new non nucleoside inhibitors of DNMT3A.

P. Arimondo, L. Halby, A. Erdmann, 2015, Bioorganic & medicinal chemistry.

Optimization of a homogeneous assay for kinase inhibitors in plant extracts.

F. Ausseil, A. Samson, I. Pouny, 2008, Assay and drug development technologies.

Asymmetric Synthesis and Binding Study of New Long-Chain HPA-12 Analogues as Potent Ligands of the Ceramide Transfer Protein CERT.

F. Ausseil, L. Fleury, C. Santos, 2016, Chemistry.

Identification of Chiral Alkenyl‐ and Alkynylcarbinols as Pharmacophores for Potent Cytotoxicity

F. Ausseil, R. Chauvin, V. Lobjois, 2013, ChemMedChem.

Dichapetalins from Dichapetalum species and their cytotoxic properties.

F. Sautel, L. Marcourt, P. Arimondo, 2013, Phytochemistry.

Bioactive flavonoids of Tanacetum parthenium revisited.

F. Ausseil, B. David, G. Massiot, 2003, Phytochemistry.

Parthenolide inhibits tubulin carboxypeptidase activity.

J. Cintrat, V. Masson, F. Ausseil, 2007, Cancer research.

Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells

P. Arimondo, V. Masson, Jean-Marc Gregoire, 2016, BMC Cancer.

Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells

P. Arimondo, V. Masson, Jean-Marc Gregoire, 2016, BMC Cancer.

Modulation of Cellular Response to Cisplatin by a Novel Inhibitor of DNA Polymerase β

U. Hübscher, F. Amalric, I. Shevelev, 2005, Molecular Pharmacology.

Development of a universal radioactive DNA methyltransferase inhibition test for high-throughput screening and mechanistic studies

P. Arimondo, Christina Gros, Y. Menon, 2013, Nucleic acids research.

Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.

M. Bouhlel, P. Arimondo, L. Halby, 2017, Journal of medicinal chemistry.

New 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidinium alkaloids (phloeodictynes) from the New Caledonian shallow-water haplosclerid sponge Oceanapia fistulosa. Structural elucidation from mainly LC-tandem-MS-soft-ionization techniques and discovery of antiplasmodial activity.

G. Guella, M. Sauvain, F. Ausseil, 2004, Organic & biomolecular chemistry.

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

L. Altucci, A. Mai, T. Ushijima, 2019, Clinical Epigenetics.

Meroterpenes from Dichrostachys cinerea inhibit protein farnesyl transferase activity.

Bruno David, Frédéric Ausseil, Catherine Lavaud, 2009, Journal of natural products.

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

L. Altucci, A. Mai, T. Ushijima, 2019, Clinical Epigenetics.

Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A.

P. Arimondo, A. Erdmann, Christina Gros, 2016, Future medicinal chemistry.

High‐Throughput Screening of Plant Chemodiversity

Bruno David, Frédéric Ausseil, F. Ausseil, 2014 .

Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.

M. Bouhlel, P. Arimondo, L. Halby, 2017, Journal of medicinal chemistry.

Proteasome inhibitors from Neoboutonia melleri.

F. Sautel, L. Marcourt, L. Vendier, 2012, Journal of natural products.

Meroterpenes from Dichrostachys cinerea inhibit protein farnesyl transferase activity.

L. Marcourt, P. Schambel, F. Ausseil, 2009, Journal of natural products.