Junchi Hu

发表

Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening.

Hualiang Jiang, M. Zheng, T. Lu, 2014, Journal of medicinal chemistry.

Small Molecule Inhibitors Targeting New Targets of Protein-Protein Interactions

C. Luo, Linjuan Li, Chen Wang, 2018 .

Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A.

Hualiang Jiang, Guang Hu, Zhongjie Liang, 2018, Biochimica et biophysica acta. General subjects.

Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors

X. Kong, C. Luo, H. Ding, 2017, Acta Pharmacologica Sinica.

Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1

Kunqian Yu, Shien Liu, C. Luo, 2017, Acta Pharmacologica Sinica.

L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression

Kaixian Chen, Hualiang Jiang, C. Luo, 2022, Journal for ImmunoTherapy of Cancer.

The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12

V. Mootha, Hongying Shen, R. Banerjee, 2017, Cell.

Inhibition of autophagy by a small molecule through covalent modification of LC3.

Kaixian Chen, Hualiang Jiang, Junyan Lu, 2021, Angewandte Chemie.

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA.

Xuemei Chen, Yinsheng Wang, Weifeng Gu, 2019, Analytical chemistry.

A Class of Disulfide Compounds Suppresses Ferroptosis by Stabilizing GPX4.

Y. Xiong, K. Guan, Junchi Hu, 2022, ACS chemical biology.

Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay

Hao Jiang, C. Luo, H. Ding, 2018, Acta Pharmacologica Sinica.

Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays.

Cheng Luo, Pan Xu, Yan Liu, 2016, Bioorganic & medicinal chemistry letters.

Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays

Jin Zhang, Yuanyuan Zhang, Shijie Chen, 2016, J. Chem. Inf. Model..

Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods.

C. Luo, Hua Zhang, K. Zhu, 2018, Biochemical and biophysical research communications.

Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search

C. Luo, H. Ding, Fanwang Meng, 2018, Molecules.

Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay

Hao Jiang, C. Luo, H. Ding, 2018, Acta Pharmacologica Sinica.

Sphondin efficiently blocks HBsAg production and cccDNA transcription through promoting HBx degradation

H. Deng, Jie-Li Hu, Juan Chen, 2023, Journal of medical virology.

An optimization algorithm for conformer generation based on the bond contribution ranking

Yongjun Dang, Junchi Hu, Kai Zhang, 2022, Comput. Biol. Chem..

A novel in vitro prognostic model of bladder cancer based on urine-derived living tumor cells

J. Hou, Jiying Zhu, Zengxia Li, 2022, Genes & diseases.

Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays

Kaixian Chen, Hualiang Jiang, M. Zheng, 2016, J. Chem. Inf. Model..