Jin-Yi Zhu

发表

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

Bryce K. Allen, E. Schönbrunn, S. Schürer, 2017, ACS omega.

Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors

S. Olesen, A. Becker, E. Schönbrunn, 2014, ACS chemical biology.

A Novel Approach to the Discovery of Small‐Molecule Ligands of CDK2

E. Schönbrunn, Mathew P. Martin, S. Betzi, 2012, Chembiochem : a European journal of chemical biology.

Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA)*

S. Olesen, Huijong Han, E. Schönbrunn, 2012, The Journal of Biological Chemistry.

Stability of the Human Hsp90-p50Cdc37 Chaperone Complex against Nucleotides and Hsp90 Inhibitors, and the Influence of Phosphorylation by Casein Kinase 2

S. Olesen, E. Schönbrunn, Mathew P. Martin, 2015, Molecules.

Structural basis of inhibitor selectivity in the BRD7/9 subfamily of bromodomains.

E. Schönbrunn, Jin-Yi Zhu, R. Karim, 2020, Journal of medicinal chemistry.

Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2).

W. Guida, E. Schönbrunn, S. Sebti, 2012, MedChemComm.

Lysine Acylation Modification Landscape of Brucella abortus Proteome and its Virulent Proteins

Pengfei Jiang, Xi Zhang, Jin-Yi Zhu, 2022, Frontiers in Cell and Developmental Biology.

Molecular glue CELMoD compounds are allosteric regulators of cereblon conformation

P. Griffin, G. Lander, I. Wertz, 2022, bioRxiv.

Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.

A. Becker, E. Schönbrunn, N. Berndt, 2021, Journal of medicinal chemistry.

Structural insights into tubulin detyrosination by vasohibins-SVBP complex

Jin-Yi Zhu, Yue Feng, Xin Liang, 2019, Cell Discovery.

Synthesis and evaluation of eight- and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase 2, and other glycosidases.

E. Schönbrunn, G. Georg, J. Tash, 2012, The Journal of organic chemistry.

Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors.

S. Olesen, E. Schönbrunn, G. Georg, 2017, Journal of medicinal chemistry.

Structure–Activity Studies of N‐Butyl‐1‐deoxynojirimycin (NB‐DNJ) Analogues: Discovery of Potent and Selective Aminocyclopentitol Inhibitors of GBA1 and GBA2

Erick J Carlson, E. Schönbrunn, G. Georg, 2017, ChemMedChem.

Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.

E. Schönbrunn, David C. Mikles, G. Georg, 2018, ACS chemical biology.

Development of o-chlorophenyl substituted pyrimidines as exceptionally potent aurora kinase inhibitors.

Huan Yang, J. Cheng, S. Sebti, 2012, Journal of medicinal chemistry.

A novel mechanism by which small molecule inhibitors induce the DFG flip in Aurora A.

E. Schönbrunn, S. Sebti, Riazul Alam, 2012, ACS chemical biology.

Potent Dual BET Bromodomain-Kinase Inhibitors as Value-Added Multitargeted Chemical Probes and Cancer Therapeutics

Patricia Greninger, C. Benes, E. Schönbrunn, 2017, Molecular Cancer Therapeutics.

BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.

Gunda I Georg, William C K Pomerantz, Ernst Schönbrunn, 2017, Journal of medicinal chemistry.

Back Cover: Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET‐BRET (ChemMedChem 23/2016)

Luke W. Koblan, Shuai Liu, Dennis L. Buckley, 2016 .

Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET‐BRET

Christopher J. Ott, Luke W. Koblan, Wei Zhang, 2016, ChemMedChem.

Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors.

W. Guida, Yan Liu, S. Sebti, 2012, Journal of medicinal chemistry.

Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal.

J. Rose, Lirong Chen, Hao Xu, 2012, Acta crystallographica. Section D, Biological crystallography.

Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor.

N. Mishra, N. Berndt, D. Harki, 2018, Journal of medicinal chemistry.

MicroRNA-155 expression with Brucella infection in vitro and in vivo and decreased serum levels of MicroRNA-155 in patients with brucellosis

Hui-Shan Cheng, Xi Zhang, Jin-Yi Zhu, 2021, Scientific Reports.

Crystal structure of a novel non‐Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S‐SAD using a Cr X‐ray source

Hao Xu, Zhi-jie Liu, Chongyun Cheng, 2008, Proteins.

Global Lysine Crotonylation Alterations of Host Cell Proteins Caused by Brucella Effector BspF

Xi Zhang, Jin-Yi Zhu, Qiao Dong, 2021, Frontiers in Cellular and Infection Microbiology.

Discovery of Diverse Small‐Molecule Inhibitors of Mammalian Sterile20‐like Kinase 3 (MST3)

S. Olesen, E. Schönbrunn, Jin-Yi Zhu, 2016, ChemMedChem.

Ubiquitin-Modified Proteome of SARS-CoV-2-Infected Host Cells Reveals Insights into Virus–Host Interaction and Pathogenesis

Y. Tong, Xi Zhang, Qianlin Li, 2021, Journal of proteome research.

Crystal structure of human VASH1-SVBP complex

Jin-Yi Zhu, Yue Feng, Xin Liang, 2019 .

Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA)*

S. Olesen, Huijong Han, E. Schönbrunn, 2012, The Journal of Biological Chemistry.

Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors.

S. Olesen, E. Schönbrunn, N. Berndt, 2017, Journal of medicinal chemistry.