Yann Lamotte

Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A).

David M. Wilson, P. Bamborough, R. Prinjha, 2012, Bioorganic & medicinal chemistry letters.

A new AMPK activator, GSK773, corrects fatty acid oxidation and differentiation defect in CPT2-deficient myotubes

O. Mirguet, Yann Lamotte, S. Mouillet-Richard, 2018, Human molecular genetics.

Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPARγ agonists.

D. Grillot, E. Nicodème, Yann Lamotte, 2014, Bioorganic & medicinal chemistry letters.

From ApoA1 upregulation to BET family bromodomain inhibition: discovery of I-BET151.

E. Nicodème, J. Kirilovsky, L. Trottet, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators.

D. Grillot, R. Gampe, Yann Lamotte, 2010, Bioorganic & medicinal chemistry letters.

Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.

O. Lequin, P. Karoyan, H. Merle-Béral, 2019, Journal of medicinal chemistry.

Naphthyridines as Novel BET Family Bromodomain Inhibitors

Lionel Trottet, Antonia Lewis, Paul Bamborough, 2014, ChemMedChem.