A. Purandare

发表

Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1).

S. Pang, G. Trainor, M. Poss, 2009, Bioorganic & medicinal chemistry letters.

Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies.

S. Pang, G. Trainor, M. Poss, 2009, Bioorganic & medicinal chemistry letters.

Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1).

S. Pang, M. Poss, L. Jayaraman, 2008, Bioorganic & medicinal chemistry letters.

Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

P. Ross-Macdonald, S. Kirov, L. Schweizer, 2015, Molecular Cancer Therapeutics.

Aminotriazine 5-HT7 antagonists.

M. Poss, D. Tortolani, A. Purandare, 2004, Bioorganic & medicinal chemistry letters.

9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors.

J. Tokarski, G. Trainor, J. Sack, 2015, Bioorganic & medicinal chemistry letters.

Janus Kinase 2 (JAK2) Inhibitors for the Treatment of Myeloproliferative Neoplasm (MPN)

M. Lorenzi, A. Purandare, L. Lombardo, 2010 .

Core exploration in optimization of chemokine receptor CCR4 antagonists.

K. McIntyre, M. Poss, Wayne Vaccaro, 2007, Bioorganic & medicinal chemistry letters.

A (1.fwdarw.4)-"trehazoloid" glucosidase inhibitor with aglycon selectivity

S. Withers, A. Purandare, S. Knapp, 1994 .

Identification of chemokine receptor CCR4 antagonist.

J. Wityak, M. Poss, Wayne Vaccaro, 2005, Bioorganic & medicinal chemistry letters.

Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2

P. Ross-Macdonald, K. McIntyre, G. Trainor, 2012, Leukemia.

Preparation of 2,7-diaminosubstituted-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitriles by solid-phase synthesis.

F. Chi, C. Cavallaro, A. Purandare, 2008, Journal of combinatorial chemistry.

Improved conditions for converting sterically hindered amides to 1,5-disubstituted tetrazoles

A. Purandare, H. Wan, G. M. Schroeder, 2010 .

Solid-phase synthesis of ‘diverse’ heterocycles

M. Poss, A. Purandare, A. Gao, 2002 .

A (1 → 4)‐“Trehazoloid” Glucosidase Inhibitor with Aglycon Selectivity.

S. Withers, A. Purandare, S. Knapp, 1995 .

Structural basis for CARM1 inhibition by indole and pyrazole inhibitors.

K. Kish, H. Klei, D. Xie, 2011, The Biochemical journal.

Kinase drug discovery approaches in chronic myeloproliferative disorders

A. Purandare, C. Kumar, F. Lee, 2009, Oncogene.

Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice.

J. Hunt, A. Kossenkov, S. Abrams, 2018, Cancer research.

Pyrrolo[1,2-f]triazines as JAK2 inhibitors: achieving potency and selectivity for JAK2 over JAK3.

David S. Nirschl, Jonathan Lippy, John S Tokarski, 2011, Bioorganic & medicinal chemistry letters.

Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor.

M. Poss, D. Tortolani, R. Borzilleri, 2021, Journal of medicinal chemistry.

Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors.

J. Tokarski, G. Trainor, J. Sack, 2015, ACS medicinal chemistry letters.

Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms.

J. Tokarski, G. Trainor, A. Mathur, 2015, ACS medicinal chemistry letters.

Antagonists of CCR4 as immunomodulatory agents.

A. Purandare, J. Somerville, 2006, Current topics in medicinal chemistry.

Optimization of CCR4 antagonists: side-chain exploration.

K. McIntyre, M. Poss, Wayne Vaccaro, 2006, Bioorganic & medicinal chemistry letters.

Substituted Diaryl Ether Compounds as Retinoic Acid-Related Orphan Receptor-γt (RORγt) Agonists.

Zhuyin Li, C. Weigelt, B. Fink, 2021, Bioorganic & medicinal chemistry letters.

Optimization of CCR4 Antagonists: Side‐Chain Exploration.

K. McIntyre, M. Poss, Wayne Vaccaro, 2006 .

Solid phase synthesis of unsymmetrical secondary amines—Application to the synthesis of arylethanolamines and arylpropanolamines

M. Poss, A. Purandare, 1998 .

Molecular Recognition and Reactivity of Ruthenium(II) Bipyridine Barbituric Acid Guests in the Presence of Complementary Hosts: Ruthenium(II) Promoted Enolization of Barbituric Acids in Guest−Host Complexes

S. S. Isied, A. Purandare, Yeung-gyo K. Shin, 1997 .

Identification of a potent and rapidly reversible inhibitor of the 20S-proteasome.

M. Poss, Wayne Vaccaro, A. Purandare, 2004, Bioorganic & medicinal chemistry letters.

Diaminopyrimidine and diaminopyridine 5-HT7 ligands.

M. Poss, A. Purandare, R. Mattson, 2004, Bioorganic & medicinal chemistry letters.

Structural basis for CARM1 inhibition by indole and pyrazole inhibitors.

K. Kish, H. Klei, D. Xie, 2011, The Biochemical journal.