D. Luttrell

发表

Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors.

P. A. Harris, J. Veal, Liping Wang, 2005, Journal of medicinal chemistry.

Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.

P. A. Harris, J. Veal, Rakesh Kumar, 2008, Journal of medicinal chemistry.

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases

L. Luttrell, D. Luttrell, 2004, Oncogene.

Relationship between vitamin D status and incidence of vascular events in the Veterans Affairs Diabetes Trial.

K. Hunt, L. Luttrell, B. Hollis, 2013, Atherosclerosis.

The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.

L. Luttrell, R. Klein, D. Luttrell, 2008, Biochemistry.

Signaling in time and space: G protein-coupled receptors and mitogen-activated protein kinases.

L. Luttrell, D. Luttrell, 2003, Assay and drug development technologies.

Role of β-Arrestin-mediated Desensitization and Signaling in the Control of Angiotensin AT1a Receptor-stimulated Transcription*

L. Luttrell, D. Luttrell, H. El-Shewy, 2008, Journal of Biological Chemistry.

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.

M. Caron, R. Lefkowitz, W. Miller, 1999, Science.

Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases*

Robert J. Lefkowitz, Louis M. Luttrell, R. Lefkowitz, 1996, The Journal of Biological Chemistry.

Regulation of mitogen-activated protein kinase pathways by catecholamine receptors.

R. Lefkowitz, B. Hawes, L. Luttrell, 1998, Advances in pharmacology.

CHAPTER 221 – Phosphorylation of G Proteins

L. Luttrell, D. Luttrell, 2003 .

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases.

R. Lefkowitz, B. Hawes, T. J. Lansing, 1996, The Journal of biological chemistry.

Longitudinal Plasma Kallikrein Levels and Their Association With the Risk of Cardiovascular Disease Outcomes in Type 1 Diabetes in DCCT/EDIC

K. Hunt, J. Lachin, T. Lyons, 2020, Diabetes.

Inflammatory Biomarkers, Glycemic Variability, Hypoglycemia, and Renal Transplant Outcomes: Results of a Randomized Controlled Trial

K. Hunt, R. Carter, M. Egidi, 2014, Transplantation.

Overexpression of pp60c-src is associated with altered regulation of adenylyl cyclase.

M. Caron, R. Lefkowitz, T. Gilmer, 1992, Cellular signalling.

Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome".

L. Luttrell, D. Luttrell, M. Kelly, 2006, The Journal of biological chemistry.

Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity.

Y. Peterson, L. Luttrell, D. Luttrell, 2013, Methods in enzymology.

pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src

J. Parsons, S. Parsons, D. Luttrell, 1989, Molecular and cellular biology.

Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor

R. Lefkowitz, L. Luttrell, T. van Biesen, 1997, The Journal of Biological Chemistry.

Levels of Connective Tissue Growth Factor (CTGF) Predict Development of Kidney Dysfunction in Type 2 Diabetes-The VADT Study

K. Hunt, L. Luttrell, A. Jaffa, 2018, Diabetes.

Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

L. Luttrell, S. Parsons, D. Luttrell, 1988, Molecular and cellular biology.

Analysis of longitudinal semicontinuous data using marginalized two-part model

M. Gebregziabher, L. Luttrell, A. Jaffa, 2018, Journal of Translational Medicine.

Overexpression of c-src enhances beta-adrenergic-induced cAMP accumulation.

S. Parsons, D. Luttrell, W. Bushman, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

R. Lefkowitz, B. Hawes, M. Sakaue, 1995, Nature.

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway.

R. Lefkowitz, B. Hawes, M. Sakaue, 1995, Nature.

Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation.

R. Lefkowitz, L. Luttrell, T. van Biesen, 1997, The Journal of biological chemistry.

Multivariate generalized linear mixed models with random intercepts to analyze cardiovascular risk markers in type-1 diabetic patients

M. Gebregziabher, L. Luttrell, A. Jaffa, 2016, Journal of applied statistics.

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

Ming-Chih Crouthamel, L. Harrington, T. Gilmer, 2007, Molecular Cancer Therapeutics.

Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors

R. Lefkowitz, L. Luttrell, Y. Daaka, 1997, The Journal of Biological Chemistry.

Plasma Kallikrein Promotes Epidermal Growth Factor Receptor Transactivation and Signaling in Vascular Smooth Muscle through Direct Activation of Protease-activated Receptors*

L. Luttrell, A. Jaffa, Bing Wang, 2010, The Journal of Biological Chemistry.

Plasma Connective Tissue Growth Factor (CTGF/CCN2) Levels Predict Myocardial Infarction in the Veterans Affairs Diabetes Trial (VADT) Cohort

K. Hunt, L. Luttrell, A. Jaffa, 2018, Diabetes Care.

Plasma Prekallikrein Is Associated With Carotid Intima-Media Thickness in Type 1 Diabetes

A. Schmaier, L. Luttrell, A. Jaffa, 2015, Diabetes.

Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.

M. Caron, R. Lefkowitz, S. Parsons, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The β-Arrestin Pathway-selective Type 1A Angiotensin Receptor (AT1A) Agonist [Sar1,Ile4,Ile8]Angiotensin II Regulates a Robust G Protein-independent Signaling Network*

M. Janech, L. Luttrell, D. Luttrell, 2011, The Journal of Biological Chemistry.

Involvement of pp60c-src with two major signaling pathways in human breast cancer.

M. Luther, T. Gilmer, T. J. Lansing, 1994, Proceedings of the National Academy of Sciences of the United States of America.