R. Mohareb

发表

Synthesis, and anti-proliferative, Pim-1 kinase inhibitors and molecular docking of thiophenes derived from estrone.

R. Mohareb, E. Samir, Peter A Halim, 2019, Bioorganic chemistry.

Synthesis and Biological Evaluation of Novel 4,5,6,7-Tetrahydrobenzo[D]-Thiazol-2-Yl Derivatives Derived from Dimedone with Anti-Tumor, C-Met, Tyrosine Kinase and Pim-1 Inhibitions.

R. Mohareb, N. S. Abbas, Amr S. Abouzied, 2019, Anti-cancer agents in medicinal chemistry.

Novel Pyrano[2,3‐ d ]thiazole and Thiazolo[4,5‐ b ]pyridine Derivatives: One‐pot Three‐component Synthesis and Biological Evaluation as Anticancer Agents, c‐Met, and Pim‐1 Kinase Inhibitors

R. Mohareb, Amira E. M. Abdallah, E. Ahmed, 2019, Journal of Heterocyclic Chemistry.

Uses of dimedone for the synthesis of thiazole derivatives as new anti-tumor, c-Met, tyrosine kinase, and Pim-1 inhibitions

T. Klapötke, E. Reinhardt, R. Mohareb, 2018, Medicinal Chemistry Research.

Uses of dimedone for the synthesis of new heterocyclic derivatives with anti-tumor, c-Met, tyrosine, and Pim-1 kinases inhibitions

W. Wardakhan, R. Mohareb, Fatma O. Al Farouk, 2018, Medicinal Chemistry Research.

The uses of cyclohexan-1,4-dione for the synthesis of thiophene derivatives as new anti-proliferative, prostate anticancer, c-Met and tyrosine kinase inhibitors

R. Mohareb, F. Al-Omran, R. Ibrahim, 2018, Medicinal Chemistry Research.

Uses of 3-(2-Bromoacetyl)-2H-chromen-2-one in the Synthesis of Heterocyclic Compounds Incorporating Coumarin: Synthesis, Characterization and Cytotoxicity

R. Mohareb, Nadia Y. MegallyAbdo, 2015, Molecules.

Multi-component reactions of cyclohexan-1,3-dione to synthesize heterocyclic derivatives with c-Met enzymatic activity, anti-prostate, anti-proliferative and tyrosine kinase activities

R. Mohareb, R. Ibrahim, E. S. Alwan, 2022, Bulletin of the Chemical Society of Ethiopia.

Synthesis and evaluation of novel 4 H ‐pyrazole and thiophene derivatives derived from chalcone as potential anti‐proliferative agents, Pim‐1 kinase inhibitors, and PAINS

R. Mohareb, E. Samir, N. Y. Megally Abdo, 2020 .

Heterocyclization of 2-(2-phenylhydrazono)cyclohexane-1,3-dione to Synthesis Thiophene, Pyrazole and Pyridazine Derivatives with Anti-Tumor and Tyrosine Kinase Inhibitions.

R. Mohareb, E. S. Alwan, E. Alwan, 2020, Anti-cancer agents in medicinal chemistry.

Uses of cyclohexan‐1,3‐dione for the synthesis of tetrahydrochromeno[3,4‐ c ]chromen derivatives with anti‐tumor activities

R. Mohareb, N. Y. Megally Abdo, M. S. Gamaan, 2020 .

Multi-component Reactions of Cyclohexan-1,3-diketones to Produce Fused Pyran Derivatives with Antiproliferative Activities and Tyrosine Kinases and Pim-1 Kinase Inhibitions.

R. Mohareb, R. Ibrahim, E. S. Alwan, 2020, Acta chimica Slovenica.

Discovery of new thiophene, pyrazole, isoxazole derivatives as antitumor, c-Met, tyrosine kinase and Pim-1 kinase inhibitors

Y. Elshehawy, R. Mohareb, K. M. H. Hilmy, 2018 .

Synthesis of Novel Thiophene, Thiazole and Coumarin Derivatives Based on Benzimidazole Nucleus and Their Cytotoxicity and Toxicity Evaluations.

R. Mohareb, A. Abdallah, Abeer A. Mohamed, 2018, Chemical & pharmaceutical bulletin.

Design, cytotoxicity and toxicity of new thiophene and thieno [2,3-b] pyridine derivatives

R. Mohareb, R. Ibrahim, 2017, Medicinal Chemistry Research.

Uses of Cyclohexan-1,4-dione for the Synthesis of 2-Amino-4,5-dihydrobenzo[b]thiophen-6(7H)-one Derivatives with Anti-proliferative and Pim-1 Kinase Activities.

R. Mohareb, N. S. Abbas, R. Ibrahim, 2017, Chemical & pharmaceutical bulletin.

Synthesis of pyridine, pyran and thiazole containing thiophene derivatives and their anti-tumor evaluations

W. Wardakhan, R. Mohareb, R. Ibrahim, 2016, Medicinal Chemistry Research.

New Approaches for the Synthesis, Cytotoxicity and Toxicity of Heterocyclic Compounds Derived from 2-Cyanomethylbenzo[c]imidazole.

R. Mohareb, A. Abdallah, Abeer A. Mohamed, 2016, Acta chimica Slovenica.

Synthesis, cytotoxicity and toxicity of thieno[2,3-d]pyrimidine derivatives derived from 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene

M. Abdelaziz, R. Mohareb, Hend M. A. El-Sehrawi, 2015, Medicinal Chemistry Research.

Synthesis, anti-inflammatory and anti-ulcer evaluations of thiazole, thiophene, pyridine and pyran derivatives derived from androstenedione

R. Mohareb, N. S. Abbas, M. Y. Zaki, 2015, Steroids.

Multicomponent Reactions of Acetoacetanilide Derivatives with Aromatic Aldehydes and Cyanomethylene Reagents to Produce 4H-Pyran and 1,4-Dihydropyridine Derivatives with Antitumor Activities.

R. Mohareb, Rasha A. Azzam, 2015, Chemical & pharmaceutical bulletin.

Synthesis and cytotoxicity of fused thiophene and pyrazole derivatives derived from 2-N-acetyl-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene

W. Wardakhan, R. Mohareb, Faten I. Hamed, 2014, Medicinal Chemistry Research.

Benzalkoniumchloride ionic liquids as novel corrosion inhibitors for carbon steel in formation water

M. Nessim, M. Deyab, R. Mohareb, 2021 .

Uses of ethyl benzoyl acetate for the synthesis of thiophene, pyran, and pyridine derivatives with antitumor activities

R. Mohareb, B. A. Ibrahim, 2020 .

Synthesis, cytotoxicity against cancer and normal cell lines of novel hydrazide–hydrazone derivatives bearing 5H-chromen-5-one

R. Mohareb, Fatma O. Al Farouk, K. El-Sharkawy, 2019, Medicinal Chemistry Research.

New approaches for the synthesis of pyrazole, thiophene, thieno[2,3-b]pyridine, and thiazole derivatives together with their anti-tumor evaluations

M. Abdelaziz, R. Mohareb, Amira E. M. Abdallah, 2013, Medicinal Chemistry Research.

New Approaches for the Use of Acetoacetanilide in the Synthesis of Thiophenes and Their Fused Derivatives with Anti-Tumor Activity

S. Sherif, W. Wardakhan, R. Mohareb, 2014 .

Studies on the synthesis of chiral nonracemic 3,4-disubstituted azepanes, a formal synthesis of (+)- and (−)-balanol

R. Mohareb, R. Neder, J. Telser, 1999 .

Synthesis of modified steroids as a novel class of non-ulcerogenic, anti-inflammatory and anti-nociceptive agents

R. Mohareb, O. Abdel-Salam, G. Elmegeed, 2011, Steroids.

Evaluation of Anti‐inflammatory, Anti‐nociceptive, and Anti‐ulcerogenic Activities of Novel Synthesized Thiazolyl and Pyrrolyl Steroids

R. Mohareb, E. F. Eskander, A. R. Baiuomy, 2011, Archiv der Pharmazie.

Synthesis and Characterization of Cationic Surfactants Based on N-Hexamethylenetetramine as Active Microfouling Agents

R. Mohareb, A. Badawi, M. Mahrous, 2015 .

Synthesis of Novel Halogenated Heterocyclic compounds and their uses as Target SARS-CoV-2 main Protease (Mpro) and Potential Anti-Covid-19

W. Wardakhan, A. Elfiky, R. Mohareb, 2021 .

Synthesis of progesterone derivatives and evaluation of their efficiency as pneumococcal vaccines

S. Sherif, R. Mohareb, K. Karaghiosoff, 2014, Medicinal Chemistry Research.

Uses of dimedone for the synthesis of thiazole derivatives as new anti-tumor, c-Met, tyrosine kinase, and Pim-1 inhibitions

T. Klapötke, E. Reinhardt, R. Mohareb, 2018, Medicinal Chemistry Research.

Uses of dimedone for the synthesis of new heterocyclic derivatives with anti-tumor, c-Met, tyrosine, and Pim-1 kinases inhibitions

W. Wardakhan, R. Mohareb, Fatma O. Al Farouk, 2018, Medicinal Chemistry Research.

Antitumor and antileishmanial evaluation of novel heterocycles derived from quinazoline scaffold: a molecular modeling approach

R. Mohareb, O. K. Sakka, D. Fleita, 2013, Medicinal Chemistry Research.

The Effect of Newly Synthesized Heterosteroids on miRNA34a, 98, and 214 Expression Levels in MCF-7 Breast Cancer Cells

R. Mohareb, S. Yahya, M. Mohamed, 2018, Indian Journal of Clinical Biochemistry.

Cyanothioacetamide in heterocyclic synthesis: a novel synthesis of 2-pyridothione derivatives

R. Mohareb, S. M. Fahmy, 1986 .

Cyanothioacetamide in Heterocyclic Synthesis: A New Approach for the Synthesis of 2-Pyridothione and 2-Pyridazinothione Derivatives

R. Mohareb, S. M. Fahmy, 1986 .

Utility of a 2‐aminothiophene‐3‐carboxamide in the synthesis of thienopyridines and thienopyrimidines

S. Sherif, Hatem M Gaber, R. Mohareb, 2003 .

Reaction of Carbon Disulfide with Active Methylenes: Novel Synthesis of Thiophene, Thieno[2,3- b ]thiophene, Thieno[3,2- c ]pyrazole and Thieno[3,2- b ]pyridine Derivatives

S. Sherif, R. Mohareb, Sami Osman, 1995 .

STUDIES WITH POLYFUNCTIONALLY SUBSTITUTED HETEROAROMATICS: THE REACTIVITY OF ALKYLAZOLES TOWARDS ELECTROPHILIC REAGENTS

S. A. Metwally, R. Mohareb, S. Zayed, 1995 .

Studies with Alkylheteroaromatic Carbonitriles: Synthesis of New Mesoionic Pyridazines, Phthalazines and Thienopyridazines.

R. Mohareb, S. El-kousy, M. Riad, 1993 .

Studies with Polyfunctionally Substituted Pyridazines: Synthesis of New 4-Coumarin-3-ylpyridazines.

R. Mohareb, M. H. Elnagdi, H. Shams, 1992 .

Novel Synthesis of 4-Bromo-3-oxo-2-phenylhydrazonobutyronitrile and 4-Cyano-3-oxo-2-phenylhydrazonobutyronitrile: Synthesis of Pyridazine, Thiazole, 1,2,4-Triazine and Pyrido[2,3- e ]-1,2,4-triazine Derivatives

R. Mohareb, N. Abdel‐Sayed, 1992 .

Synthesis and biological effects of new derivatives of benzotriazole as antimicrobial and antifungal agents

R. Mohareb, F. Al-Omran, A. El-Khair, 2002 .

SYNTHETIC POTENTIALITIES OF THIOPHENE SYSTEMS IN HETEROCYCLIC SYNTHESIS: A NOVEL SYNTHESIS OF THIENO[2,3-b]PYRIDINE DERIVATIVES

Y. M. Elkholy, R. Mohareb, H. Shams, 1999 .

The synthetic potentialities of nitriles in heterocyclic synthesis

S. Sherif, R. Mohareb, M. H. Elnagdi, 1987 .

The Reaction of 4-Phenyl-3-Thiosemicarbazide With β-Bifunctional Compounds: Novel Synthesis of Pyridine And Pyrazole Derivatives

Y. M. Elkholy, R. Mohareb, 1994 .

Reactions with Acetoacetanilide: New approaches for the Synthesis of Polyfunctionally Substituted Pyridine Derivatives

R. Mohareb, S. M. Fahmy, A. Habashi, 1986 .

Novel synthesis of pyran, thiophene, and pyridine derivatives incorporating thiazole ring and their antitumor evaluation

R. Mohareb, Amira E. M. Abdallah, E. Khalil, 2020 .

Synthesis and structure elucidation of some novel thiophene and benzothiophene derivatives as cytotoxic agents

R. Mohareb, A. Abdallah, M. H. Helal, 2016, Acta pharmaceutica.

Synthesis, Structure Elucidation, and Biological Evaluation of Some Fused and/or Pendant Thiophene, Pyrazole, Imidazole, Thiazole, Triazole, Triazine, and Coumarin Systems Based on Cyanoacetic 2-[(Benzoylamino)thioxomethyl] Hydrazide

M. Helal, R. Mohareb, M. H. Helal, 2007 .

γ-BROMOACETOACETANILIDES IN HETEROCYCLIC SYNTHESIS: A CONVENIENT SYNTHESIS OF POLYFUNCTIONALLY SUBSTITUTED 2,3-DIHYDROTHIAZOLE, PYRIDIN-2-ONE, 1,2,3-TRIAZINE, OXAZOLO[3,4-b]PYRIDINE AND PYRAZOLO[3,4-b]PYRIDINE DERIVATIVES

S. Sherif, R. Mohareb, N. Abdel‐Sayed, 1991 .

Nitriles in Heterocyclic Synthesis: New Approaches to the Synthesis of Some Pyridine Derivatives.

R. Mohareb, N. S. Ibrahim, H. Shams, 1989 .

Cyanothioacetamide in Heterocyclic Synthesis: A New Approach for the Synthesis of 2-Pyridothione and 2-Pyridazinothione Derivatives.

R. Mohareb, S. M. Fahmy, 1986 .

Novel Synthesis and Antitumor Evaluation of Polyfunctionally Substituted Heterocyclic Compounds Derived from 2-Cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide

R. Mohareb, M. H. Helal, H. Shams, 2010, Molecules.

Reaction of pregnenolone with cyanoacetylhydrazine: Novel synthesis of hydrazide–hydrazone, pyrazole, pyridine, thiazole, thiophene derivatives and their cytotoxicity evaluations

R. Mohareb, F. Al-Omran, 2012, Steroids.

The Reaction of Cyclohexan-1,3-dione with Cyanomethylenes: Synthesis of Thiophenes and Their Fused Derivatives with Antifungal Activities

S. Sherif, R. Mohareb, H. Moustafa, 2009 .

Uses of ethyl benzoylacetate for the synthesis of thiophene, thiazole, pyridine, and pyran derivatives with antitumor activities

R. Mohareb, Bahaa M. Mostafa, 2020 .

Synthesis of Novel Heterocyclic Compounds Incorporate 4,5,6,7-Tetrahydrobenzo[b]thiophene Together with Their Cytotoxic Evaluations.

R. Mohareb, E. Khalil, A. Abdallah, 2017, Chemical & pharmaceutical bulletin.

NOVEL SYNTHESIS OF PYRAN-3-HYDRAZIDE DERIVATIVES AND THEIR USES TO THE SYNTHESIS HYDRAZIDE-HYDRAZONE, PYRAZOLE AND THIAZOLE DERIVATIVES WITH ANTICANCER ACTIVITIES

R. Mohareb, E. Samir, 2022 .

New route for synthesis, spectroscopy, and X-ray studies of 2-[aryl-(6′-hydroxy-4′,4′-dimethyl-2′-oxocyclohex-6′-enyl)methyl]-3-hydroxy-5,5-dimethylcyclohex-2-enone and 1,8-dioxo-octahydroxanthenes and antitumor evaluation

R. Mohareb, F. Al-Omran, A. El-Khair, 2014, Medicinal Chemistry Research.

Cytotoxicity, tyrosine kinase inhibition of novel pyran, pyridine, thiophene, and imidazole derivatives

R. Mohareb, Rasha A. Azzam, M. H. Helal, 2020, Journal of Heterocyclic Chemistry.

Uses of dimedone to synthesis pyrazole, isoxazole and thiophene derivatives with antiproliferative, tyrosine kinase and Pim-1 kinase inhibitions

R. Mohareb, M. A. Mahmoud, F. M. Manhi, 2020, Medicinal Chemistry Research.

Synthesis and cytotoxicity evaluation of thiazole derivatives obtained from 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene- 3-carbonitrile

R. Mohareb, E. Ahmed, A. Abdallah, 2017, Acta pharmaceutica.

Synthesis and Cytotoxic Evaluation of Pyran, Dihydropyridine and Thiophene Derivatives of 3-Acetylcoumarin.

R. Mohareb, N. Y. Megally Abdo, 2015, Chemical & pharmaceutical bulletin.

Polyfunctionally Substituted Pyridines from Cyanoacetamide and Cyanoacetanilide

R. Mohareb, H. Shams, S. M. Fahmy, 1987 .

Heterocyclic synthesis with isothiocyantes: Synthesis of several new polyfunctionally substituted thiophene, Δ4‐thiazoline and thiazolidinone derivatives

S. Sherif, R. Mohareb, Rafat Milad Mohareb, 1991 .

One‐pot synthesis of polyfunctionally substituted 2,3‐dihydrothiazoles and thiazolidinones

S. Sherif, R. Mohareb, N. I. Sayed, 1990 .

Synthesis of new disperse azo dyes based on oxopyridine core

M. Helal, R. Mohareb, I. Samir, 2008 .

The reaction of 2‐amino‐3‐cyano‐4,5,6,7‐tetrahydrobenzo[b]‐thiophene with diethyl malonate: synthesis of coumarin, pyridine, and thiazole derivatives

R. Mohareb, J. Ho, Fatma A. El-Omran, 2001 .

Enantiospecific synthesis of carbapentostatins.

T. Sim, R. Mohareb, H. Rapoport, 2003, The Journal of organic chemistry.

The Knoevenagel reaction of cyanoacetylhydrazine with pregnenolone: Synthesis of thiophene, thieno[2,3-d]pyrimidine, 1,2,4-triazole, pyran and pyridine derivatives with anti-inflammatory and anti-ulcer activities

W. Wardakhan, M. Abdelaziz, R. Mohareb, 2016, Steroids.

Anti-tumor and anti-leishmanial evaluations of 1,3,4-oxadiazine, pyran derivatives derived from cross-coupling reactions of β-bromo-6H-1,3,4-oxadiazine derivatives.

J. Schatz, R. Mohareb, 2011, Bioorganic & medicinal chemistry.

Multicomponent Reactions of Acetoacetanilide Derivatives with Aromatic Aldehydes and Cyanomethylene Reagents to Produce 4H-Pyran and 1,4-Dihydropyridine Derivatives with Antitumor Activities.

R. Mohareb, Rasha A. Azzam, 2015, Chemical & pharmaceutical bulletin.

Uses of Cyclohexan-1,3-dione for the Synthesis of Thiazole, Pyrazole, Thiophene, Isoxazole and Pyran Derivatives with Antitumor Activities

R. Mohareb, N. Y. Megally Abdo, W. N. Al-darkazali, 2020 .

Synthesis of tetrahydropyrazolo-quinazoline and tetrahydropyrazolo-pyrimidocarbazole derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors

R. Mohareb, N. S. Abbas, A. A. Mohamed, 2017, Medicinal Chemistry Research.

Syntheses, crystal structures, in vitro antitumor and free radical scavenging activity evaluation of a series of 2-substituted thiophenes

R. Mohareb, K. Mahmoud, O. K. Sakka, 2015, Medicinal Chemistry Research.

Anti‐proliferative Activities of Thiophenes, Pyrans and PyridinesDerived from 1,3‐Dicarbonyl Compounds

S. Khasim, R. Mohareb, M. Alsharif, 2021, ChemistrySelect.

Design and Synthesis of Novel Antimicrobial Acyclic and Heterocyclic Dyes and Their Precursors for Dyeing and/or Textile Finishing Based on 2-N-Acylamino-4,5,6,7-tetrahydro-benzo[b]thiophene Systems

R. Mohareb, M. H. Helal, H. Shams, 2011, Molecules.

Reaction of 2‐amino‐3‐cyano‐4,5,6,7‐tetrahydrobenzo‐[b]thiophene with ethyl acetoacetate: Novel syntheses of pyridines, pyrazoles, and their fused derivatives

R. Mohareb, M. H. Mohamed, 2001 .

Heterocyclic synthesis with isothiocyanates : an expeditious synthetic route for polyfunctionally substituted 3-(thiazol-2'-ylidene)pyridines and their fused derivatives

S. Sherif, R. Mohareb, H. F. Zohdi, 1994 .

Reactions of Benzoylisothiocyanate with Acetoacetanilide: Synthesis of Pyrazole, Pyridine, Pyrimidine, Pyrazolo[3,4- d ]pyrimidine, Pyrazolo[4,3- d ]pyrimidine and Pyrido[4,3- d ]oxazine Derivatives

R. Mohareb, N. Abdel‐Sayed, S. I. Aziz, 1993 .

Substituted 4,5,6,7-tetrahydroindoles and their fused derivatives. Synthesis and cytotoxic activity towards tumor and normal human cell lines

M. Abdelaziz, R. Mohareb, 2013, Chemistry of Heterocyclic Compounds.

Hybrid probes of aromatic amine and barbituric acid: highly promising leads for anti-bacterial, anti-fungal and anti-cancer activities

Bhaveshkumar D. Dhorajiya, R. Mohareb, B. Dholakiya, 2014, Medicinal Chemistry Research.

New approaches for the synthesis of pyrazole, thiophene, thieno[2,3-b]pyridine, and thiazole derivatives together with their anti-tumor evaluations

M. Abdelaziz, R. Mohareb, A. Abdallah, 2014, Medicinal Chemistry Research.

Hydrazide-Hydrazones in the Synthesis of 1,3,4-Oxadiazine, 1,2,4-Triazine and Pyrazole Derivatives with Antitumor Activities~!2010-02-19~!2010-06-08~!2010-08-27~!

R. Mohareb, R. Ibrahim, H. Moustafa, 2010 .

Synthesis of Thiophenes, Azoles and Azines with Potential Biological Activity by Employing the Versatile Heterocyclic Precursor N-Benzoycyanoacetylhydrazine

R. Mohareb, J. Ho, Fatma O. Alfarouk, 2007 .

Synthesis and anti-tumor evaluation of novel hydrazide and hydrazide-hydrazone derivatives

W. Wardakhan, R. Mohareb, El-Sayed Nahed Nasser Eid, 2013, Acta pharmaceutica.

NOVEL SYNTHESIS OF HYDRAZIDE-HYDRAZONE AND THEIR USES FOR THE SYNTHESIS 1,3,4-OXADIAZINE, 1,2,4-TRIAZINE, PYRAZOLE AND PYRIDAZINE DERIVATIVES WITH ANTIMICROBIAL AND ANTIFUNGAL ACTIVITIES

R. Mohareb, A. Egypt, 2011 .

Novel Synthesis of Hydrazide-Hydrazone Derivatives and Their Utilization in the Synthesis of Coumarin, Pyridine, Thiazole and Thiophene Derivatives with Antitumor Activity

R. Mohareb, O. K. Sakka, D. Fleita, 2010, Molecules.

β‐Enaminonitriles in Heterocyclic Synthesis: A Novel One‐Pot Synthesis of Thiophenes and Their Fused Derivatives.

S. Sherif, W. Wardakhan, R. Mohareb, 1996 .

R. Mohareb, F. Al-Omran, A. El-Khair, 2013, Medicinal Chemistry Research.

Synthesis and E/Z Configuration Determination of Novel Derivatives of 3-Aryl-2-(benzothiazol-2'-ylthio) Acrylonitrile, 3-(Benzothiazol-2'-ylthio)-4-(furan-2''-yl)-3-buten-2-one and 2-(1-(Furan-2''-yl)-3'-oxobut-1''-en-2-ylthio)-3-phenylquinazolin-4(3H)-one

R. Mohareb, F. Al-Omran, A. El-Khair, 2011, Molecules.

New Approaches for the Uses of Cyclohexan-1,4-dione for the Synthesis of 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-b]pyridine Derivatives used as Potential Anti-prostate Cancer Agents and Pim-1 Kinase Inhibitors.

R. Mohareb, K. El-Sharkawy, N. Y. M. Abdo, 2019, Anti-cancer agents in medicinal chemistry.

Heterocyclic ring extension of estrone: Synthesis and cytotoxicity of fused pyran, pyrimidine and thiazole derivatives

R. Mohareb, F. Al-Omran, Rasha A. Azzam, 2014, Steroids.

The utilization of 2-aminoprop-1-ene-1,1,3-tricarbonitrile as a precursor to quinoline, furan and thiophene derivatives with antitumor activities

R. Mohareb, O. K. Sakka, D. Fleita, 2011 .

The reaction of β-amino-α,γ-dicyanocrotononitrile with acetophenone: Synthesis of pyridine, pyridazine and thiophene derivatives with antimicrobial activities

S. Sherif, R. Mohareb, K. El-Sharkawy, 2008, Acta pharmaceutica.

The Knoevenagel reaction of malononitrile with acetylacetone: New route of pyrazole, pyrazolo[2,3-C]pyridine, benzene, pyridazine and benzo[C]pyridazine derivatives

R. Mohareb, 1991 .

Dimerised ethyl cyanoacetate in heterocyclic dye synthesis: New pyridine azodyes and tetrazole dyes

R. Mohareb, S. M. Fahmy, F. A. Abd‐All, 2007 .

Design, Synthesis, Molecular Docking and Biological Studies of 4 H ‐Benzo[ d ][1,3]oxazin‐4‐one Derivatives and Their Uses in Heterocyclic Synthesis

R. Mohareb, R. Ibrahim, A. A. Mohamed, 2022, ChemistrySelect.

Development of new indole-derived neuroprotective agents.

R. Mohareb, H. Ahmed, G. Elmegeed, 2011, Bioorganic & medicinal chemistry.

Uses of Cyanoacetylhydrazine in Heterocyclic Synthesis: Novel Synthesis of Pyrazole Derivatives with Anti-tumor Activities

M. Abdelaziz, R. Mohareb, Nahed N E El-Sayed, 2012, Molecules.

Uses of 1-Cyanoacetyl-4-Phenyl-3- Thiosemicarbazide in the Synthesis of Antimicrobial and Antifungal Heterocyclic Compounds

R. Mohareb, 2012 .

The Reaction of Cyanoacetylhydrazine with ω-Bromo(4-methyl)acetophenone: Synthesis of Heterocyclic Derivatives with Antitumor Activity

R. Mohareb, A. A. Mohamed, 2010, Molecules.

Heterocyclization of 2-Arylidencyclohexan-1,3-dione: Synthesis of Thiophene, Thiazole and Isoxazole Derivatives with Potential Antitumor Activities.

R. Mohareb, N. Y. M. Abdo, W. N. Al-darkazali, 2019, Anti-cancer agents in medicinal chemistry.

Antitumor and antileishmanial evaluation of novel heterocycles derived from quinazoline scaffold: a molecular modeling approach

R. Mohareb, O. K. Sakka, D. Fleita, 2012, Medicinal Chemistry Research.

New Approaches for the Synthesis of Heterocyclic Compounds Derived from Cyclohexan-1,3-dione with Anti-proliferative Activities.

R. Mohareb, Y. Milad, Ayat Ali Masoud, 2021, Acta chimica Slovenica.

Anti-Tumor and Anti-Leishmanial Evaluations of Novel Thiophene Derivatives Derived from the Reaction of Cyclopentanone with Elemental Sulphur and Cyano-Methylene Reagents

R. Mohareb, F. O. Al-farouk, 2012 .

Synthesis of progesterone heterocyclic derivatives of potential antimicrobial activity

R. Mohareb, Hanaa Y. Hana, 2008, Acta pharmaceutica.

The Reaction of Cyanoacetylhdrazine with Furan-2-Aldehyde: Novel Synthesis of Thiophene, Azole, Azine and Coumarin Derivatives and Their Antitumor Evaluation

S. Sherif, W. Wardakhan, R. Mohareb, 2012 .

Convenient Heterocyclization Reactions with Ethyl 2‐Amino‐4,5,6,7‐ tetrahydrobenzo(b)thiophene‐3‐carboxylate: Synthesis of Thiazole, Isoxazole, Pyrazole, Pyrimidine and Pyridazine Derivatives.

W. Wardakhan, R. Mohareb, H. F. Zohdi, 1997 .

HETEROCYCLIC SYNTHESIS WITH ISOTHIOCYANATE AND SULFUR: A NOVEL ROUTE FOR THE SYNTHESIS OF PYRIDINO[2,3-d]THIAZOLE, THIAZOLO[4′,5′:2,3] PYRIDINO[4,3-d]PYRIDAZINE AND THIAZOLO[4,5-b]ISOQUINOLINE DERIVATIVES

W. Wardakhan, R. Mohareb, H. F. Zohdi, 1995 .

Thiophenylhydrazonoacetates in heterocyclic synthesis

S. Sherif, Hatem M Gaber, R. Mohareb, 2004 .

The Reaction of Cyanoacetic Acid Hydrazide with 2-Acetylfuran: Synthesis of Coumarin, Pyridine, Thiophene and Thiazole Derivatives with Potential Antimicrobial Activities

R. Mohareb, K. El-Sharkawy, E. E. El-Arab, 2009 .

Novel pregnenolone derivatives modulate apoptosis via Bcl-2 family genes in hepatocellular carcinoma in vitro

R. Mohareb, W. Khalil, H. Rady, 2018, The Journal of Steroid Biochemistry and Molecular Biology.

Hydrazide-Hydrazones in the Synthesis of 1,3,4-Oxadiazine, 1,2,4-Triazineand Pyrazole Derivatives with Antitumor Activities

R. Mohareb, R. Ibrahim, H. Moustafa, 2010 .

Cytotoxicity and gene expression profiles of novel synthesized steroid derivatives as chemotherapeutic anti-breast cancer agents.

R. Mohareb, W. Khalil, H. Ahmed, 2011, Bioorganic & medicinal chemistry.

α‐Halo ketoximes in Heterocyclic Synthesis: Polyfunctional Azoles and Azines from α‐Bromo ketoximes

S. Sherif, R. Mohareb, E. A. Hafez, 1987 .

Synthesis and Application of Novel Reactive Disperse Dye Based on Tetrahydrobenzo[b] Thiophene Moiety

F. Mohamed, R. Mohareb, 2014 .

An efficient procedure for the preparation of (1S,3R)- and (1S,3S)-1-amino-3-(hydroxymethyl)cyclopentanes.

T. Sim, R. Mohareb, H. Rapoport, 2003, Chemical & pharmaceutical bulletin.

THE USES OF POLYFUNCTIONALLY SUBSTITUTED THIOPHENES IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF BENZO[b]THIOPHENE, THIENO[2,3-b] PYRIDINE DERIVATIVES

Y. M. Elkholy, R. Mohareb, N. I. Sayed, 1995 .

THE REACTION OF CYANOACETYLHYDRAZINE WITH w-BROMOACETOPHENONE: NOVEL SYNTHESIS OF 1,3,4-OXADIAZINE, PYRIDAZINE AND COUMARIN DERIVATIVES

R. Mohareb, R. Ibrahim, J. Ho, 2007 .

Reaction of 4-aryl-3-thiosemicarbazides with carbon disulfide: A facile synthesis of 2,3-dihydrothiazoles and their fused derivatives

S. Sherif, R. Mohareb, 1997 .

Reaction of 3-Cyano-2-diazo-4,5,6,7-tetrahydrobenzo[ b ]thiophene with 3-Imino-butyronitrile: Synthesis of Pyridazines, Thiophenes and Their Fused Derivatives

R. Mohareb, K. M. H. Hilmy, A. El-torgman, 2003 .

Uses of 4,4-dicyano-3-phenyl-but-3-enoic acid phenylamide for the synthesis of new compounds: antimicrobial and textile finishing evaluations

R. Mohareb, Amira E. M. Abdallah, 2019, Pigment & Resin Technology.

Heterocyclic ring extension of androstenedione: Synthesis and cytotoxicity of fused pyran, pyrimidine and thiazole derivatives

M. Abdelaziz, R. Mohareb, N. S. Abbas, 2014, Steroids.

Heterocyclizations of pregnenolone: Novel synthesis of thiosemicarbazone, thiophene, thiazole, thieno[2,3-b]pyridine derivatives and their cytotoxicity evaluations

W. Wardakhan, R. Mohareb, G. Elmegeed, 2012, Steroids.

Heterocyclic compounds derived from cyclohexane-1,4-dione: synthesis of tetrahydro-4H-chromene and tetrahydrobenzo[d]thiazole derivatives as target SARS-CoV-2 main protease (Mpro) and potential anti-Covid-19

R. Mohareb, N. Y. Megally Abdo, 2021, Journal of the Iranian Chemical Society.

HETEROCYCLIC SYNTHESIS WITH ISOTHIOCYANATES: A CONVENIENT SYNTHESIS OF POLYFUNCTIONALLY SUBSTITUTED 2,3-DIHYDROTHIAZOLE, 2-(PYRAZOL-4′-YL)-THIAZOLE, 5-(THIAZOL-2′-YL)PYRIMIDINE AND THIAZOLO[3,2-a]PYRIDINE DERIVATIVES

S. Sherif, R. Mohareb, Abeer M. Samy, 1995 .

Reaction of Malononitrile and Ethyl Cyanoacetate: a Novel Synthesis of Polyfunctional Pyridine Derivatives

R. Mohareb, S. M. Fahmy, 1985 .

Conducting Scientific Research: Research Hypothesis and Null Hypothesis

Rafat M. Mohareb, R. Mohareb, 2012 .

Evaluation of heterocyclic steroids and curcumin derivatives as anti-breast cancer agents: Studying the effect on apoptosis in MCF-7 breast cancer cells

R. Mohareb, S. Yahya, M. Mohamed, 2016, Steroids.

Reaction of Benzoyl Isothiocyanate With Active Methylene Reagents: A Convenient Synthesis of Pyrazolo[5,4-c]pyrazole, 1,3-Oxazine, Thiazole and Pyrimidine Derivatives

S. Sherif, R. Mohareb, N. S. Ibrahim, 1987 .

Phenyl isothiocyanate in heterocyclic synthesis: Novel synthesis of thiazoles, thieno[2,3-b]pyridine, thiophene and thieno[3,2-c]pyridazine derivatives

R. Mohareb, 1992 .

Reaction of Benzoyl Isothiocyanate with Active Methylene Reagents: A Convenient Synthesis of Pyrazolo(5,4-c)pyrazole, 1,3-Oxazine, Thiazole and Pyrimidine Derivatives.

S. Sherif, R. Mohareb, N. S. Ibrahim, 1987 .

Reaction of 3-phenyl-5-aminopyrazole with carbon disulfide: A novel synthesis of 3-(3′-phenylpyrazol-5′-yl)-4-phenylpyrazol-2-thione as well as of pyrazolo[3,4-d]thiazole and pyrano[2,3-d]thiazole derivatives

W. Wardakhan, R. Mohareb, H. F. Zohdi, 1995 .

New Approaches for the Synthesis of 2,3,5,6-Tetrahydrobenzo[d]thiazole Derivatives and their Anti- proliferative , c-Met Enzymatic Activity and Tyrosine Kinases Inhibitions.

M. Helal, R. Mohareb, S. S. Mohamed, 2021, Anti-cancer agents in medicinal chemistry.

Multi-Component Reactions of Cyclohexan-1,3-dione: Synthesis of Fused Pyran, Pyridine, Thiophene and Pyrazole Derivatives with c-Met, AntiProliferative Activities.

R. Mohareb, Abeer A. Mohamed, Amira M. Elmetwally, 2021, Anti-cancer agents in medicinal chemistry.

The Knoevenagel reactions of pregnenolone with cyanomethylene reagents: Synthesis of thiophene, thieno[2,3-b]pyridine, thieno[3,2-d]isoxazole derivatives of pregnenolone and their in vitro cytotoxicity towards tumor and normal cell lines

R. Mohareb, Mahmoud A Abdelaziz, N. El-Sayed, 2013, Steroids.

Synthesis of progesterone derivatives and evaluation of their efficiency as pneumococcal vaccines

S. Sherif, R. Mohareb, K. Karaghiosoff, 2014, Medicinal Chemistry Research.

Synthesis of Pyridine and Spiropyridine Derivatives Derived from 2-aminoprop- 1-ene-1,1,3-tricarbonitrile Together with their c-Met Kinase and Antiproliferative Evaluations.

R. Mohareb, N. S. Abbas, A. Abouzied, 2017, Anti-Cancer Agents in Medicinal Chemistry.

Activated Nitriles in Heterocyclic Synthesis: A Noval Synthesis of Polyfunctionally Substituted Pyridine Derivatives

R. Mohareb, S. M. Fahmy, S. O. A. Allah, 1984 .

Anti-inflammatory and Anti-ulcer Activities of New Fused Thiazole Derivatives Derived from 2-(2-Oxo-2H-chromen-3-yl)thiazol-4(5H)-one.

M. Abdelaziz, R. Mohareb, F. Al-Omran, 2017, Acta chimica Slovenica.

Synthesis of hydrazide-hydrazone derivatives and their evaluation of antidepressant, sedative and analgesic agents

R. Mohareb, K. El-Sharkawy, M. M. Hussein, 2010 .

Synthesis, cytotoxicity and toxicity of thieno[2,3-d]pyrimidine derivatives derived from 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene

M. Abdelaziz, R. Mohareb, Hend M. A. El-Sehrawi, 2015, Medicinal Chemistry Research.

Reaction of 4‐Aryl‐3‐thiosemicarbazides with Phenylisothiocyanate: A Facile Synthesis of Thiazole, Pyrazole and Pyrimidine Derivatives

W. Wardakhan, R. Mohareb, D. Fleita, 1999 .

Sultamo-Steroid analogues, part VII: Synthesis of epi-androsterone derivatives with potential activity

R. Mohareb, G. Elmegeed, S. H. Doss, 1999, Archives of pharmacal research.

Synthesis, Structure Activity Relationships and Biological Activity Evaluation of Novel Spirocyclic Thiazolidin-4-ones as Potential Anti-Breast Cancer and Epidermal Growth Factor Receptor Inhibitors

R. Mohareb, O. K. Sakka, D. Fleita, 2013, Drug Research.

The Uses of 4-Aryl-3-Thiosemicarbazides in Heterocyclic Synthesis: Synthesis of Coumarin, Pyrazole, Thiazole and Thiophene Derivatives

W. Wardakhan, R. Mohareb, S. S. Ghabrial, 1998 .

A Convenient Synthesis of Polyfunctionally Substituted Benzo(b) thiophen‐2‐yl‐pyrimidine, ‐pyrazole, ‐isoxazole, and ‐pyridazine Derivatives.

S. Sherif, R. Mohareb, H. Shams, 1996 .

THE USES OF 4-PHENYL-3-THIOSEMICARBAZIDE IN HETEROCYCLIC SYNTHESIS: NOVEL SYNTHESIS OF THIAZOLE, PYRAZOLE AND 1,3,4-THIADIAZINE DERIVATIVES

R. Mohareb, H. Shams, Y. M. Elkholy, 1992 .

Novel Synthesis of 4-(Coumarin-3-yl)-1,3-thiazole, 2-(Coumarin-3- carbonyl)thieno(2,3-b)pyridine and 2-(Coumarin-3-carbonyl)thiophene Derivatives.

R. Mohareb, H. Shams, S. I. Aziz, 1992 .

The Use of 4‐Phenyl‐3‐thiosemicarbazide in Heterocyclic Synthesis: Novel Synthesis of Thiazole, Pyrazole and 1,3,4‐Thiadiazine Derivatives.

Y. M. Elkholy, R. Mohareb, H. Shams, 1993 .

Synthesis and docking studies of pyran, pyridine and thiophene derivatives and their antitumor evaluations against cancer, hepatocellular carcinoma and cervical carcinoma cell lines

R. Mohareb, E. Samir, R. Ibrahim, 2023, Journal of the Iranian Chemical Society.

Hybrid probes of aromatic amine and barbituric acid: highly promising leads for anti-bacterial, anti-fungal and anti-cancer activities

Bhaveshkumar D. Dhorajiya, R. Mohareb, B. Dholakiya, 2014, Medicinal Chemistry Research.

Synthesis and cytotoxicity of fused thiophene and pyrazole derivatives derived from 2-N-acetyl-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene

W. Wardakhan, R. Mohareb, Faten I. Hamed, 2015, Medicinal Chemistry Research.

Design, Synthesis, Molecular Docking and Biological Studies of New Heterocyclic Compounds Derived from -Diketonesas Novel EGFR and Pim-1 Inhibitors Endowed with Antitumor Activity.

R. Mohareb, I. T. Radwan, Noha Bagato, 2022, Anti-cancer agents in medicinal chemistry.

Uses of -diketones for the synthesis of novel heterocyclic compounds and their antitumor evaluations

R. Mohareb, M. Kamel, Y. Milad, 2020 .

The uses of ethyl 2-(1H-benzo[D]imidazol-2-yl)acetate to synthesis pyrazole, thiophene, pyridine and coumarin derivatives with antitumor activities

R. Mohareb, M. S. Gamaan, 2018 .

Synthesis of Heterocyclic Compounds Derived From Dimedone and their Anti-tumor and Tyrosine Kinase Inhibitions.

R. Mohareb, F. M. Manhi, Amal Abdelwahab, 2020, Acta chimica Slovenica.

The Effect of Newly Synthesized Heterosteroids on miRNA34a, 98, and 214 Expression Levels in MCF-7 Breast Cancer Cells

R. Mohareb, S. Yahya, M. Mohamed, 2017, Indian Journal of Clinical Biochemistry.

Anti-proliferative and morphological studies of 2-(benzo[d]thiazol-2-yl) derivatives together with their strategy in ionic liquids immobilized reactions

R. Mohareb, R. Ibrahim, F. O. Al Farouk, 2024, Journal of the Iranian Chemical Society.