F. Valentine

发表

Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin.

D. Weiner, D. Meruelo, G. Lavie, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy.

E A Emini, D. Richman, D. Havlir, 1997, The New England journal of medicine.

Population Pharmacokinetic Analysis of Didanosine (2′,3′‐Dideoxyinosine) Plasma Concentrations Obtained in Phase I Clinical Trials in Patients with AIDS or AIDS‐Related Complex

F. Valentine, C. Mclaren, R. Dolin, 1992, Journal of clinical pharmacology.

Cell-mediated immunity.

F. Valentine, H. Lawrence, 1971, Advances in internal medicine.

Delayed-type hypersensitivity to recombinant HIV envelope glycoprotein (rgp160) after immunization with homologous antigen.

D. Katzenstein, T. Merigan, B. Smoller, 1999 .

A randomized, placebo-controlled study of the immunogenicity of human immunodeficiency virus (HIV) rgp160 vaccine in HIV-infected subjects with > or = 400/mm3 CD4 T lymphocytes (AIDS Clinical Trials Group Protocol 137).

D. Katzenstein, T. Merigan, P. Haslett, 1996, The Journal of infectious diseases.

Shipment Impairs Lymphocyte Proliferative Responses to Microbial Antigens

Rebecca A. Betensky, Elizabeth Connick, Alan L. Landay, 2000, Clinical Diagnostic Laboratory Immunology.

Results of the flow cytometry ACTG quality control program: analysis and findings.

J. Fahey, J. Giorgi, N. Flomenberg, 1989, Clinical immunology and immunopathology.

Toxicity of combined ganciclovir and zidovudine for cytomegalovirus disease associated with AIDS. An AIDS Clinical Trials Group Study.

C. Pettinelli, S. Spector, D. Dieterich, 1990, Annals of internal medicine.

Requirement of precommitted cells as targets for the augmentation of lymphocyte proliferation by leukocyte dialysates

R. Holzman, F. Valentine, H. Lawrence, 1976, The Journal of experimental medicine.

Immunological memory after exposure to variola virus, monkeypox virus, and vaccinia virus.

F. Ennis, W. Borkowsky, P. Pazoles, 2007, The Journal of infectious diseases.

Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor

T. Ndung’u, Jeffrey N. Martin, F. Hecht, 2015, Proceedings of the National Academy of Sciences.

Evidence of dysregulation of dendritic cells in primary HIV infection

K. Shianna, J. Fellay, M. Markowitz, 2010, Blood.

Delayed-type hypersensitivity to recombinant HIV envelope glycoprotein (rgp160) after immunization with homologous antigen.

D. Katzenstein, T. Merigan, B. Smoller, 1999, Journal of acquired immune deficiency syndromes.

Immunological and virological surrogate markers in the evaluation of therapies for HIV infection.

M. Jacobson, F. Valentine, 1990, AIDS (London).

Measurement of antiretroviral drugs in the lungs of HIV-infected patients.

H. Twigg, R. Collman, F. Valentine, 2010, HIV therapy.

A reverse transcriptase assay for early diagnosis of infant HIV infection in resource-limited settings.

K. Mandaliya, F. Valentine, S. Sivapalasingam, 2007, Journal of tropical pediatrics.

The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults.

P. Volberding, J. Gallant, M. Saag, 2002, AIDS research and human retroviruses.

Lymphocytes from some long-term seronegative heterosexual partners of HIV-infected individuals proliferate in response to HIV antigens.

F. Valentine, M. Seidlin, H. Kelker, 1992, AIDS research and human retroviruses.

Impact of bioavailability on determination of the maximal tolerated dose of 2',3'-dideoxyinosine in phase I trials

J. Lambert, G. Drusano, F. Valentine, 1992, Antimicrobial Agents and Chemotherapy.

Relationship between Dideoxyinosine Exposure, CD4 Counts, and p24 Antigen Levels in Human Immunodeficiency Virus Infection

J. Lambert, G. Drusano, F. Valentine, 1992, Annals of Internal Medicine.

Phase I study of 2',3'-dideoxyinosine: experience with 19 patients at New York University Medical Center.

H. Hochster, F. Valentine, M. Seidlin, 1990, Reviews of infectious diseases.

Didanosine: long-term follow-up of patients in a phase 1 study.

J. Lambert, R. Reichman, F. Valentine, 1993, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Reduced Langerhans' cell Ia antigen and ATPase activity in patients with the acquired immunodeficiency syndrome.

G. Thorbecke, F. Valentine, R. Baer, 1984, The New England journal of medicine.

Cytotoxicity of natural killer cells: correlation with emperipolesis and surface enzymes.

F. Valentine, E. Burns, D. Zucker‐Franklin, 1982, Laboratory investigation; a journal of technical methods and pathology.

Early Detection of HIV Infection Among Kenyan Infants Using a Reverse Transcriptase Activity Assay

R. Holzman, F. Valentine, S. Sivapalasingam, 2012, The Pediatric Infectious Disease Journal.

A micromethod for evaluating the phagocytic activity of human macrophages by ingestion of radio-labelled polystyrene particles.

F. Valentine, M. Al-Ibrahim, H. Lawrence, 1976, Journal of immunological methods.

Immunogenic and antigenic properties of an HIV-1 gp120-derived multiple chain peptide.

F. Valentine, D. Schlesinger, H. Kelker, 1994, Journal of immunology.

Pathogenesis of the immunological deficiencies caused by infection with the human immunodeficiency virus.

F. Valentine, Fred T. Valentine, 1990, Seminars in oncology.

Viral commensalism in humans?

M. Blaser, F. Valentine, 2008, The Journal of infectious diseases.

Interaction of mononuclear leukocytes with malignant melanoma.

F. Valentine, D. Zucker‐Franklin, N. Fujinami, 1981, Laboratory investigation; a journal of technical methods and pathology.

Implementation of a validated peripheral neuropathy screening tool in patients receiving antiretroviral therapy in Mombasa, Kenya.

R. Holzman, F. Valentine, S. Sivapalasingam, 2010, The American journal of tropical medicine and hygiene.

Lymphocyte Stimulation: Transfer of Cellular Hypersensitivity to Antigen in vitro

F. Valentine, H. Lawrence, Fred T. Valentine, 1969, Science.

SOLUBLE FACTORS PRODUCED BY LYMPHOCYTES *

F. Valentine, 1974, Annals of the New York Academy of Sciences.

TRANSFER FACTOR IN DELAYED HYPERSENSITIVITY *

F. Valentine, H. Lawrence, F. T. Valentine, 1970, Annals of the New York Academy of Sciences.

Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome—related complex

F. Valentine, C. Mclaren, R. Dolin, 1991, Clinical pharmacology and therapeutics.

2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. A phase I trial.

C. Pettinelli, J. Lambert, R. Reichman, 1990, The New England journal of medicine.

Extended follow-up of peripheral neuropathy in patients with AIDS and AIDS-related complex treated with dideoxyinosine.

J. Lambert, K. Kieburtz, R. Reichman, 1992, Journal of acquired immune deficiency syndromes.

27 – LYMPHOCYTE TRANSFORMATION: THE PROLIFERATION OF HUMAN BLOOD LYMPHOCYTES STIMULATED BY ANTIGEN IN VITRO

F. Valentine, 1971 .

Transfer factor and other mediators of cellular immunity.

F. Valentine, H. Lawrence, 1970, The American journal of pathology.

Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure.

J. Skurnick, S. Vermund, D. Nixon, 2002, Journal of Infectious Diseases.

Immunophenotype of human melanoma cells in different metastases.

J. Bystryn, F. Valentine, P. Liu, 1985, Cancer research.

CELLULAR IMMUNITY IN VITRO : CLONAL PROLIFERATION OF ANTIGEN-STIMULATED LYMPHOCYTES

F. Valentine, H. Lawrence, W. Marshall, 1969 .

Activity, safety, and immunological effects of hydroxyurea added to didanosine in antiretroviral-naive and experienced HIV type 1-infected subjects: a randomized, placebo-controlled trial, ACTG 307.

C. Flexner, R. Bosch, I. Frank, 2004, AIDS research and human retroviruses.

Dual vs single protease inhibitor therapy following antiretroviral treatment failure: a randomized trial.

Victor DeGruttola, Florin Vaida, S. Hammer, 2002, JAMA.

Low CD4+ T cell nadir is an independent predictor of lower HIV-specific immune responses in chronically HIV-1-infected subjects receiving highly active antiretroviral therapy.

S. Kalams, T. Gebretsadik, A. Shintani, 2006, The Journal of infectious diseases.

3-Year Suppression of HIV Viremia with Indinavir, Zidovudine, and Lamivudine

J. Mellors, J. Condra, J. Chodakewitz, 2000, Annals of Internal Medicine.

Analysis of potential risk factors associated with the development of pancreatitis in phase I patients with AIDS or AIDS-related complex receiving didanosine.

M. Beltangady, F. Valentine, R. Dolin, 1994, The Journal of infectious diseases.

A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy

Joel E Gallant, Calvin Cohen, Edwin DeJesus, 2003, AIDS.

Effects of dialyzable transfer factor in patients with breast cancer.

L. Old, H. Oettgen, F. Valentine, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Zidovudine Compared With Didanosine in Patients With Advanced HIV Type I Infection and Little or No Previous Experience With Zidovudine

K. K. Lai, D. Katzenstein, M. Hirsch, 1995 .

Effect of therapeutic immunization with recombinant gp160 HIV-1 vaccine on HIV-1 proviral DNA and plasma RNA: relationship to cellular immune responses.

B. Efron, D. Katzenstein, T. Merigan, 1997, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection.

W. Borkowsky, D. Littman, N. Manel, 2010, The Journal of infectious diseases.

Within-subject variation in CD4 lymphocyte count in asymptomatic human immunodeficiency virus infection: implications for patient monitoring.

D S Stein, M D Hughes, M. Hughes, 1994, The Journal of infectious diseases.

LEUCOCYTE DIALYSATES REQUIRE PRECOMMITTED, ANTIGEN-REACTIVE CELLS TO AUGMENT LYMPHOCYTE PROLIFERATION

R. Holzman, F. Valentine, H. Lawrence, 1976 .

Incomplete immune reconstitution after initiation of highly active antiretroviral therapy in human immunodeficiency virus-infected patients with severe CD4+ cell depletion.

N. Roberts, J. McCutchan, M. McElrath, 2003, The Journal of infectious diseases.

26 – THE PREPARATION OF A LYMPHOCYTE TRANSFORMING FACTOR FROM SENSITIVE LYMPHOCYTES STIMULATED BY ANTIGEN

F. Valentine, 1971 .

Daily Low-Dose Subcutaneous Interleukin-2 Added To Single- or Dual-Nucleoside Therapy in HIV Infection Does Not Protect Against CD4+ T-Cell Decline or Improve Other Indices of Immune Function: Results of a Randomized Controlled Clinical Trial (ACTG 248)

M. Lederman, R. Gelman, K. Squires, 2004, Journal of acquired immune deficiency syndromes.

A novel immunization strategy using cytokine/chemokines induces new effective systemic immune responses, and frequent complete regressions of human metastatic melanoma

D. Roses, F. Valentine, M. Harris, 2018, Oncoimmunology.

Activated lymphocytes depress phagocytosis of latex particles by human monocyte-macrophages.

F. Valentine, M. Al-Ibrahim, H. Lawrence, 1978, Cellular Immunology.

Phase I Studies of Hypericin, the Active Compound in St. John's Wort, as an Antiretroviral Agent in HIV-Infected Adults: AIDS Clinical Trials Group Protocols 150 and 258

C. Crumpacker, J. Holden-Wiltse, F. Valentine, 1999, Annals of Internal Medicine.

Implementation of HIV testing at 2 New York City bathhouses: from pilot to clinical service.

W. Borkowsky, K. Bernstein, J. Aberg, 2009, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The proliferative response of human lymphocytes to antigen is suppressed preferentially by lymphocytes precultured with the same antigen.

W. Borkowsky, F. Valentine, 1979, Journal of Immunology.

Sex differences in the incidence of peripheral neuropathy among Kenyans initiating antiretroviral therapy.

R. Holzman, F. Valentine, S. Sivapalasingam, 2011, Clinical Infectious Diseases.

Effect of highly active antiretroviral therapy on viral burden in the lungs of HIV-infected subjects.

R. Collman, R. Bassett, F. Valentine, 2008, The Journal of infectious diseases.

CD4+ blood lymphocytes are rapidly killed in vitro by contact with autologous human immunodeficiency virus-infected cells.

M. Schechter, F. Valentine, B. Nardelli, 1995, Proceedings of the National Academy of Sciences of the United States of America.

A review of the flow cytometry quality control program of the national institutes of health AIDS program

R. Gelman, F. Valentine, M. Waxdal, 1990 .

The Development and Implementation of an Outreach Program to Identify Acute and Recent HIV Infections in New York City

F. Valentine, M. Marmor, Robert Hagerty, 2010, The open AIDS journal.

A Strategy for Eliciting Antibodies against Cryptic, Conserved, Conformationally Dependent Epitopes of HIV Envelope Glycoprotein

F. Valentine, V. Itri, H. Kelker, 2010, PloS one.

Monitoring Virologic Responses to Antiretroviral Therapy in HIV-Infected Adults in Kenya: Evaluation of a Low-Cost Viral Load Assay

R. Holzman, F. Valentine, S. Sivapalasingam, 2009, PloS one.

Preparation and properties of cloning inhibitory factor. I. Inhibition of HeLa cell cloning by stimulated lymphocytes and their culture supernatants.

R. Holzman, F. Valentine, H. Lawrence, 1973, Cellular immunology.

Preparation and properties of cloning inhibitory factor. II. Factors affecting its production and assay.

R. Holzman, F. Valentine, H. Lawrence, 1973, Cellular immunology.

Safety and Efficacy of zidovudine in asymptomatic HIV infected individuals withless than 500 CD4+ cells/mm3.

S. Lagakos, D. Richman, C. Pettinelli, 1990 .

In vitro properties of leukocyte dialysates containing transfer factor.

M. Ascher, F. Valentine, H. Lawrence, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Human Th 17 cells are susceptible to HIV and are perturbed during infection

W. Borkowsky, D. Littman, N. Manel, 2010 .

CELLULAR IMMUNITY IN VITRO

F. Valentine, H. Lawrence, W. Marshall, 1969, Journal of Experimental Medicine.

Lymphocyte-proliferative responses to HIV antigens as a potential measure of immunological reconstitution in HIV disease.

A. Saito, R. Holzman, F. Valentine, 1998, AIDS research and human retroviruses.

Neurological outcomes in late HIV infection: adverse impact of neurological impairment on survival and protective effect of antiviral therapy. AIDS Clinical Trial Group and Neurological AIDS Research Consortium study team.

M. Lederman, C. Yiannoutsos, K. Marder, 1999, AIDS.

Zidovudine in Asymptomatic Human Immunodeficiency Virus Infection

S W Lagakos, M. Hirsch, T. Merigan, 1990 .

Residual human immunodeficiency virus (HIV) Type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years.

D. Richman, H. Günthard, S. Frost, 2001, The Journal of infectious diseases.

The Transformation and Proliferation of Lymphocytes in vitro1

F. Valentine, 1971 .

IN VITRO COMPARISON OF TFDM OBTAINED FROM SKIN TEST POSITIVE AND NEGATIVE INDIVIDUALS

R. Holzman, F. Valentine, H. Lawrence, 1976 .

Human Immunodeficiency Virus (HIV) Reverse Transcriptase Activity Correlates with HIV RNA Load: Implications for Resource-Limited Settings

R. Holzman, F. Valentine, S. Sivapalasingam, 2005, Journal of Clinical Microbiology.

CELLULAR IMMUNITY IN VITRO

F. Valentine, H. Lawrence, W. Marshall, 1969, The Journal of experimental medicine.

A Controlled Phase Ii Trial Assessing Three Doses of Enfuvirtide (T-20) in Combination with Abacavir, Amprenavir, Ritonavir and Efavirenz in Non-Nucleoside Reverse Transcriptase Inhibitor-Naive HIV-Infected Adults

Gary Richmond, Edwin DeJesus, Richard Haubrich, 2002, Antiviral therapy.

Pancreatitis and pancreatic dysfunction in patients taking dideoxyinosine

J. Lambert, F. Valentine, R. Dolin, 1992, AIDS.

Characterization of the cell population mediating cytotoxicity and emperipolesis in human malignant melanomas.

F. Valentine, E. Burns, D. Zucker‐Franklin, 1981, Transactions of the Association of American Physicians.