A. Boer

发表

Drug transport across the blood-brain barrier

M. Danhof, D. Breimer, J. B. M. M. Bree, 1992, Pharmaceutisch Weekblad.

Modulators of Blood-Brain Barrier (BBB) Permeability: In Vitro and in Vivo Drug Transport to the Brain

D. Breimer, A. Boer, P. Gaillard, 2001 .

Blood-brain barrier permeability and stress; a study excitotoxic stress and vasogenic edema

D. Breimer, A. Boer, P. Gaillard, 1996 .

CHITOSAN AND CHITOSAN DERIVATIVES AS ABSORPTION ENHANCERS FOR PEPTIDE DRUGS ACROSS MUCOSAL EPITHELIA

H. Junginger, C. Lehr, M. Thanou, 1999 .

Drug transport to the brain: in vitro versus in vivo approaches

M. Danhof, J. Kuiper, H. D. Vries, 1994 .

The Application of Microdialysis Techniques to the Study of Drug Transport Across the Blood–Brain Barrier

D. Breimer, A. Boer, E. D. Lange, 2000 .

Transport of peptide and protein drugs across biological membranes

H. Junginger, J. Bouwstra, H. Boddé, 1990, European Journal of Drug Metabolism and Pharmacokinetics.

Peptide transport across the blood-brain barrier☆

M. Danhof, D. Breimer, J. B. M. M. Bree, 1990 .

Drug transport across the blood-brain barrier

M. Danhof, D. Breimer, J. B. M. M. Bree, 1993, Pharmacy World and Science.

Synthetic hydrogels as drug delivery systems

H. Junginger, J. Bouwstra, H. Boddé, 2005, Pharmaceutisch Weekblad.

Influence of food on the bioavailability of metoprolol from an OROS system; a study in healthy volunteers

H. Schoemaker, A. Cohen, A. Boer, 1990, European Journal of Clinical Pharmacology.

Mucoadhesive polymers in peroral peptide drug delivery. V. Effect of poly(acrylates) on the enzymatic degradation of peptide drugs by intestinal brush border membrane vesicles

H. Junginger, H. Merkle, P. Langguth, 1996 .

Novel peroral dosage forms with protease inhibitory activities. I. Design of capsules with fast gel-forming and fast drug-releasing properties

H. Junginger, A. Boer, J. Verhoef, 1996 .

Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro

H. Junginger, C. Lehr, A. Boer, 1997 .

Application of intracerebral microdialysis to study regional distribution kinetics of drugs in rat brain

M. Danhof, D. Breimer, J. Mandema, 1995, British journal of pharmacology.

Eicosanoid production by rat cerebral endothelial cells: Stimulation by lipopolysaccharide, interleukin-1 and interleukin-6

J. Kuiper, T. J. Berkel, F. Zijlstra, 1995, Journal of Neuroimmunology.

Characterization of the Scavenger Receptor on Bovine Cerebral Endothelial Cells In Vitro

J. Kuiper, T. J. Berkel, D. Breimer, 1993, Journal of neurochemistry.

Lymphocyte adhesion to brain capillary endothelial cells in vitro

A. Moor, J. Kuiper, T. J. Berkel, 1994, Journal of Neuroimmunology.

Novel peroral dosage forms with protease inhibitory activities. II. Design of fast dissolving poly(acrylate) and controlled drug-releasing capsule formulations with trypsin inhibiting properties

H. Junginger, A. Boer, J. Verhoef, 1996 .

Chitosans for enhanced delivery of therapeutic peptides across intestinal epithelia: in vitro evaluation in Caco-2 cell monolayers

H. Junginger, A. Boer, A. F. Kotzé, 1997 .

Comparative population structure analysis of Campylobacter jejuni from human and poultry origin in Bangladesh

H. Endtz, A. van Belkum, K. Talukder, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

Control of Salmonella in poultry using bacteriophage

J. Wagenaar, A. Boer, P. Barrow, 2006 .

Rectal bioavailability of lidocaine in man: Partial avoidance of “first‐pass” metabolism

H. Mattie, D. Breimer, A. Boer, 1979, Clinical pharmacology and therapeutics.

Rectal Drug Administration

D. Breimer, A. Boer, F. Moolenaar, 1982, Clinical pharmacokinetics.

Pharmacokinetics of Rectal Drug Administration, Part II

D. Breimer, A. Boer, E. J. Hoogdalem, 1991, Clinical pharmacokinetics.

Pharmacokinetics of Rectal Drug Administration, Part I

D. Breimer, A. Boer, E. J. Hoogdalem, 1991, Clinical pharmacokinetics.

Pharmacokinetics of Lignocaine and Bupivacaine in Surgical Patients Following Epidural Administration

N. Vermeulen, D. Breimer, A. Burm, 1987, Clinical pharmacokinetics.

Abstracts of papers

D. Crommelin, A. Porsius, C. Lerk, 2005, Pharmaceutisch Weekblad.

Abstracts of Dutch doctoral theses

R. A. Zeeuw, G. J. Jong, M. J. M. Zeeland, 2005, Pharmaceutisch Weekblad.

Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood–brain barrier

Meindert Danhof, M. Danhof, D. Breimer, 1997, Brain Research Reviews.

MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG DELIVERY. I. INFLUENCE OF MUCOADHESIVE EXCIPIENTS ON THE PROTEOLYTIC ACTIVITY OF INTESTINAL ENZYMES

H. Junginger, C. Lehr, A. Boer, 1996 .

Improvement of drug absorption through enhancers

D. Breimer, A. Boer, E. J. Hoogdalem, 1990, European Journal of Drug Metabolism and Pharmacokinetics.

(D) Routes of delivery: Case studies

D. Breimer, A. Boer, E. J. Hoogdalem, 1992 .

Bioadhesive polymers for the peroral delivery of peptide drugs

Claus-Michael Lehr, Hans E. Junginger, H. L. Lueßen, 1994 .

The influence of cytokines on the integrity of the blood-brain barrier in vitro

J. Kuiper, T. J. Berkel, H. D. Vries, 1996, Journal of Neuroimmunology.

Cell-polarity dependent effect of chelation on the paracellular permeability of confluent caco-2 cell monolayers

D. Breimer, A. Boer, Y. Kurosaki, 1993 .

The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro

Gerrit Borchard, Hans E. Junginger, H. Junginger, 1996 .

Drug transport across the blood — brain barrier

M. Danhof, D. Breimer, J. B. M. M. Bree, 1992, Pharmaceutisch Weekblad.

Effects of the Mucoadhesive Polymer Polycarbophil on the Intestinal Absorption of a Peptide Drug in the Rat

H. Junginger, J. Bouwstra, C. Lehr, 1992, The Journal of pharmacy and pharmacology.

Rate‐controlled Absorption Enhancement of Rectally Administered Cefazolin in Rats by a Glyceride Mixture (MGK)

D. Breimer, A. Boer, E. J. Hoogdalem, 1988, The Journal of pharmacy and pharmacology.

Absorption Enhancement of a Hydrophilic Model Compound by Verapamil After Rectal Administration to Rats

D. Breimer, A. Boer, A. Noach, 1995, The Journal of pharmacy and pharmacology.

Rectal absorption enhancement of rate-controlled delivered ampicillin sodium by sodium decanoate in conscious rats

D. Breimer, A. Boer, E. J. Hoogdalem, 1988, Pharmaceutisch Weekblad.

Hepatic first-pass effect and controlled drug delivery following rectal administration

D. Breimer, A. Boer, 1997 .

3‐Amino‐1‐hydroxypropylidene‐1,1‐diphosphonate (APD): a novel enhancer of rectal cefoxitin absorption in rats

D. Breimer, A. Boer, A. Wackwitz, 1989, The Journal of pharmacy and pharmacology.

Rate-controlled absorption enhancement of rectally administered cefoxitin in rats by salicylate

D. Breimer, A. Boer, E. J. Hoogdalem, 1988 .

The Blood – Brain Barrier and its Effect on Absorption and Distribution

A. Boer, P. Gaillard, 2010 .

‘First-pass’ eliminatie van enige ‘high-clearance’ farmaca na rectale toediening aan de mens en de rat

A. Boer, 1980, Pharmaceutisch Weekblad.

Critical factors of intracerebral microdialysis as a technique to determined the pharmacokinetics of drugs in rat brain

Meindert Danhof, M. Danhof, D. Breimer, 1994, Brain Research.

Implications of P–glycoprotein for the Transport and Distribution of Drugs into the Brain

D. Breimer, A. Boer, I. D. Sandt, 2004 .

The unit impulse response procedure for the pharmacokinetic evaluation of drug entry into the central nervous system

M. Danhof, D. Breimer, J. B. M. M. Bree, 1989, Journal of Pharmacokinetics and Biopharmaceutics.

Synthetic hydrogels as drug delivery systems

H. Junginger, H. Boddé, A. Boer, 1986, Pharmaceutisch Weekblad.

Chapter 20 Cytokines and blood-brain barrier permeability

D. Breimer, A. Boer, 1998 .

PLASMA LEVEL PROFILE OF NITRAZEPAM (MOGADON®) FOLLOWING ORAL ADMINISTRATION

H. Bracht, D. Breimer, A. Boer, 1977 .

The influence of components on the rectal absorption of cefazolin in rats

D. Breimer, A. Boer, E. J. Hoogdalem, 1988, The Journal of pharmacy and pharmacology.

Reconstitution of the blood-brain barrier in cell culture for studies of drug transport and metabolism

D. Breimer, A. Boer, 1996 .

Strategies to Improve Drug Delivery Across the Blood-Brain Barrier

A. Boer, P. Gaillard, 2007, Clinical pharmacokinetics.

Avoidance of first pass elimination of propranolol after rectal administration to rats

D. Breimer, A. Boer, J. Gubbens-Stibbe, 1981, The Journal of pharmacy and pharmacology.

Repeated microdialysis perfusions: periprobe tissue reactions and BBB permeability

M. Danhof, D. Breimer, A. Boer, 1995, Brain Research.

Rectal and intravenous propranolol infusion to steady state: Kinetics and β‐receptor blockade

D. Breimer, A. Boer, C. Hug, 1984, Clinical pharmacology and therapeutics.

Zero-order release of oxprenolol-HCl, a new approach

H. Junginger, D. Breimer, A. Boer, 1988 .

Abstracts of papers Pharmacological meeting

N. Ramsey, J. M. Ree, M. Danhof, 1985, Pharmaceutisch Weekblad.

Drug Delivery to the Brain by Internalizing Receptors at the Blood‐Brain Barrier

A. Boer, P. Gaillard, C. Visser, 2007 .

Influence of salicylate and anaesthesia on the rectal absorption of theophylline in rats

D. Breimer, A. Boer, E. J. Hoogdalem, 1986, Pharmaceutisch Weekblad.

A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain–Barré syndrome

H. Endtz, J. Wagenaar, A. Belkum, 2013, European Journal of Clinical Microbiology & Infectious Diseases.

Radioimmunoassay of desglycinamide-arginine vasopressin and its application in a pharmacokinetic study in the rat

M. Danhof, D. Breimer, J. B. M. M. Bree, 1988, Peptides.

Improved Oral Peptide Delivery by Means of Mucoadhesion

H. Junginger, J. Bouwstra, C. Lehr, 1990 .

In vitro penetration of des-tyrosine1-D-phenylalanine3-β-casomorphin across the blood-brain barrier

H. Stark, U. Jaehde, D. Breimer, 1992, Peptides.

Diphtheria toxin receptor-targeted brain drug delivery

A. Boer, P. Gaillard, A. Brink, 2005 .

Interaction of liposomes with lipopolysaccharide: influence of time, serum and liposome composition

D. Crommelin, M. Danhof, L. Bloois, 2005 .

Blood-brain barrier transport rate of quinoline antibacterials evaluated in cerebrovascular endothelial cell cultures

U. Jaehde, D. Breimer, A. Boer, 1993 .

POPULATION PHARMACOKINETIC MODELLING OF BLOOD-BRAIN BARRIER TRANSPORT OF SYNTHETIC ADENOSINE A 1 RECEPTOR AGONISTS

J. DeJongh, M. Danhof, A. IJzerman, 2004 .

Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs.

M Danhof, D D Breimer, M. Danhof, 1988, The Journal of pharmacology and experimental therapeutics.

Volume Regulation of the in Vitro Blood-Brain Barrier by Osmoreactive Amino Acids during Stress

D. Breimer, A. Boer, P. Gaillard, 1996 .

A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain–Barré syndrome

H. Endtz, A. van Belkum, P. van Baarlen, 2012, European Journal of Clinical Microbiology & Infectious Diseases.

Effect of apical and/or basolateral application of EDTA on the permeability of hydrophilic compounds in a human intestinal epithelial cell-line (Caco-2)

D. Breimer, A. Boer, A. Noach, 1992 .

Assay of propranolol in human and rat plasma by capillary gas chromatography with nitrogen selective detection

D. Breimer, A. Boer, J. Gubbens-Stibbe, 1980, Pharmaceutisch Weekblad.