Yanmin Hu

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High-dose rifampicin kills persisters, shortens treatment duration, and reduces relapse rate in vitro and in vivo

D. Mitchison, Yanmin Hu, Alexander Liu, 2015, Front. Microbiol..

A Mycobacterium tuberculosis Mutant Lacking the groEL Homologue cpn60.1 Is Viable but Fails To Induce an Inflammatory Response in Animal Models of Infection

G. Besra, P. Lund, B. Henderson, 2008, Infection and Immunity.

Enhancement by novel anti-methicillin-resistant Staphylococcus aureus compound HT61 of the activity of neomycin, gentamicin, mupirocin and chlorhexidine: in vitro and in vivo studies.

Yanmin Hu, A. Coates, 2013, The Journal of antimicrobial chemotherapy.

A Novel erm(44) Gene Variant from a Human Staphylococcus saprophyticus Isolate Confers Resistance to Macrolides and Lincosamides but Not Streptogramins

V. Perreten, Yanmin Hu, A. Coates, 2016, Antimicrobial Agents and Chemotherapy.

A novel erm ( 44 ) gene variant from a human Staphylococcus saprophyticus 3 confers resistance to macrolides , lincosamides but not streptogramins

V. Perreten, Yanmin Hu, A. Coates, 2016 .

Zidovudine enhances activity of carbapenems against NDM-1-producing Enterobacteriaceae

Yanmin Hu, A. Coates, 2021, The Journal of antimicrobial chemotherapy.

Azidothymidine Produces Synergistic Activity in Combination with Colistin against Antibiotic-Resistant Enterobacteriaceae

Yanmin Hu, A. Coates, Yingjun Liu, 2018, Antimicrobial Agents and Chemotherapy.

Bedaquiline kills persistent Mycobacterium tuberculosis with no disease relapse: an in vivo model of a potential cure.

G. Davies, Yanmin Hu, A. Coates, 2019, The Journal of antimicrobial chemotherapy.

Sterilizing Activities of Fluoroquinolones against Rifampin-Tolerant Populations of Mycobacterium tuberculosis

D. Mitchison, Yanmin Hu, A. Coates, 2003, Antimicrobial Agents and Chemotherapy.

Mycobacterial Heat Shock Protein 60s in the Induction and Regulation of Infectious Disease

Yanmin Hu, A. Coates, A. Cehovin, 2009 .

Optimal doses of rifampicin in the standard drug regimen to shorten tuberculosis treatment duration and reduce relapse by eradicating persistent bacteria

T. Harrison, G. Davies, Yanmin Hu, 2018, The Journal of antimicrobial chemotherapy.

The Efficacy of Using Combination Therapy against Multi-Drug and Extensively Drug-Resistant Pseudomonas aeruginosa in Clinical Settings

A. Coates, Yanmin Hu, Frank Jones, 2022, Antibiotics.

Urinary bactericidal activity of colistin and azidothymidine combinations against mcr-1-positive colistin-resistant Escherichia coli.

Yanmin Hu, A. Coates, K. Naber, 2019, International journal of antimicrobial agents.

The future challenges facing the development of new antimicrobial drugs

R. Bax, C. Page, Yanmin Hu, 2002, Nature Reviews Drug Discovery.

Transcription of the Stationary-Phase-AssociatedhspX Gene of Mycobacterium tuberculosis Is Inversely Related to Synthesis of the 16-Kilodalton Protein

Yanmin Hu, A. Coates, 1999, Journal of bacteriology.

Targeting non-multiplying organisms as a way to develop novel antimicrobials.

Yanmin Hu, A. Coates, 2008, Trends in pharmacological sciences.

A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis

Yanmin Hu, A. Coates, U. Simonsson, 2020, Journal of Pharmacokinetics and Pharmacodynamics.

New strategies for antibacterial drug design: targeting non-multiplying latent bacteria.

A. Coates, Yanmin Hu, 2006, Drugs in R&D.

Nordihydroguaiaretic acid enhances the activities of aminoglycosides against methicillin- sensitive and resistant Staphylococcus aureus in vitro and in vivo

Yanmin Hu, A. Coates, Edward Cunningham-Oakes, 2015, Front. Microbiol..

New Strategies for Antibacterial Drug Design

Yanmin Hu, A. Coates, 2006 .

Transposon mutagenesis identifies genes which control antimicrobial drug tolerance in stationary-phase Escherichia coli.

Yanmin Hu, A. Coates, 2005, FEMS microbiology letters.

Nonmultiplying bacteria are profoundly tolerant to antibiotics.

Yanmin Hu, A. Coates, 2012, Handbook of experimental pharmacology.

Antimicrobial Peptide Novicidin Synergizes with Rifampin, Ceftriaxone, and Ceftazidime against Antibiotic-Resistant Enterobacteriaceae In Vitro

Yanmin Hu, Alexander Liu, A. Coates, 2015, Antimicrobial Agents and Chemotherapy.

Moxifloxacin Replacement in Contemporary Tuberculosis Drug Regimens Is Ineffective against Persistent Mycobacterium tuberculosis in the Cornell Mouse Model

S. Gillespie, G. Davies, Yanmin Hu, 2018, Antimicrobial Agents and Chemotherapy.

Mefloquine enhances the activity of colistin against antibiotic-resistant Enterobacterales in vitro and in vivo animal studies.

Yanmin Hu, A. Coates, 2021, International journal of antimicrobial agents.

Novel classes of antibiotics or more of the same?

A. Coates, Yanmin Hu, Gerry Halls, 2011, British journal of pharmacology.

Same Exposure but Two Radically Different Responses to Antibiotics: Resilience of the Salivary Microbiome versus Long-Term Microbial Shifts in Feces

David A. Spratt, Bernd W. Brandt, Mark J. Buijs, 2015, mBio.

Antibiotic combination therapy against resistant bacterial infections: synergy, rejuvenation and resistance reduction

P. Yeh, A. Coates, Yanmin Hu, 2019, Expert review of anti-infective therapy.

Combinations of β-Lactam or Aminoglycoside Antibiotics with Plectasin Are Synergistic against Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus

A. Kearns, Yanmin Hu, Alexander Liu, 2015, PloS one.

Sudden cardiac death and tuberculosis - how much do we know?

Yanmin Hu, Alexander Liu, A. Coates, 2012, Tuberculosis.

A model of catheter‐associated urinary tract infection initiated by bacterial contamination of the catheter tip

Yanmin Hu, A. Coates, K. Anson, 2008, BJU international.

Can We Prevent Antimicrobial Resistance by Using Antimicrobials Better?

Yanmin Hu, A. Coates, Germander Soothill, 2013, Pathogens.

Transcription of Two Sigma 70 Homologue Genes,sigA and sigB, in Stationary-PhaseMycobacterium tuberculosis

Yanmin Hu, A. Coates, 1999, Journal of bacteriology.

Mycobacterium tuberculosis , in Stationary-Phase sigB and sigA Genes , Transcription of Two Sigma 70 Homologue

Yanmin Hu, A. Coates, 1998 .

Comparison of the Moonlighting Actions of the Two Highly Homologous Chaperonin 60 Proteins of Mycobacterium tuberculosis

B. Henderson, C. Botanch, Y. Riffo-Vasquez, 2010, Infection and Immunity.

A New Approach for the Discovery of Antibiotics by Targeting Non-Multiplying Bacteria: A Novel Topical Antibiotic for Staphylococcal Infections

Yanmin Hu, A. Coates, Yanmin Hu, 2010, PloS one.

Synergistic activity of colistin with azidothymidine against colistin-resistant Klebsiella pneumoniae clinical isolates collected from inpatients in Greek hospitals.

M. Falagas, A. Coates, Yanmin Hu, 2019, International journal of antimicrobial agents.

Conventional Antibiotics – Revitalized by New Agents

Yanmin Hu, A. Coates, 2014 .

The Mycobacterium tuberculosis sigJ gene controls sensitivity of the bacterium to hydrogen peroxide.

N. Stoker, Yanmin Hu, A. Coates, 2004, FEMS microbiology letters.

A biphasic response from bladder epithelial cells induced by catheter material and bacteria: an in vitro study of the pathophysiology of catheter related urinary tract infection.

Yanmin Hu, A. Coates, K. Anson, 2008, The Journal of urology.

Translational Model‐Informed Approach for Selection of Tuberculosis Drug Combination Regimens in Early Clinical Development

S. Wicha, A. Coates, Yanmin Hu, 2020, Clinical pharmacology and therapeutics.

Forecasting Clinical Dose–Response From Preclinical Studies in Tuberculosis Research: Translational Predictions With Rifampicin

Robin J. Svensson, S. Wicha, S. Gillespie, 2018, Clinical pharmacology and therapeutics.

A multistate tuberculosis pharmacometric model: a framework for studying anti-tubercular drug effects in vitro

Ulrika S H Simonsson, Yanmin Hu, A. Coates, 2015, The Journal of antimicrobial chemotherapy.

Defining dormancy in mycobacterial disease.

Vincent O. Baron, S. Gillespie, S. Lipworth, 2016, Tuberculosis.

Deletion of the Mycobacterium tuberculosis α-Crystallin-Like hspX Gene Causes Increased Bacterial Growth In Vivo

F. Movahedzadeh, N. Stoker, Yanmin Hu, 2006, Infection and Immunity.

3‐Ketosteroid 9α‐hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis

Mahavir Singh, G. Besra, M. Rohde, 2010, Molecular microbiology.

Serum bactericidal activity of colistin and azidothymidine combinations against mcr-1-positive colistin-resistant Escherichia coli.

Yanmin Hu, A. Coates, K. Naber, 2018, International journal of antimicrobial agents.

Acute and Persistent Mycobacterium tuberculosis Infections Depend on the Thiol Peroxidase TPX

Yanmin Hu, A. Coates, 2009, PloS one.

Effect of Different Media on the Bactericidal Activity of Colistin and on the Synergistic Combination With Azidothymidine Against mcr-1-Positive Colistin-Resistant Escherichia coli

Yanmin Hu, A. Coates, K. Naber, 2020, Frontiers in Microbiology.

Detection of mRNA Transcripts and Active Transcription in Persistent Mycobacterium tuberculosisInduced by Exposure to Rifampin or Pyrazinamide

P. Butcher, D. Mitchison, Yanmin Hu, 2000, Journal of bacteriology.

Regulation of hmp Gene Transcription inMycobacterium tuberculosis: Effects of Oxygen Limitation and Nitrosative and Oxidative Stress

M. Rajandream, P. Butcher, Yanmin Hu, 1999, Journal of bacteriology.

Mycobacterium tuberculosis acg Gene Is Required for Growth and Virulence In Vivo

Yanmin Hu, A. Coates, 2011, PloS one.

Contradictory Results with High-Dosage Rifamycin in Mice and Humans

D. Mitchison, Yanmin Hu, A. Coates, 2013, Antimicrobial Agents and Chemotherapy.

Identification of the monocyte activating motif in Mycobacterium tuberculosis chaperonin 60.1.

P. Lund, B. Henderson, Yanmin Hu, 2013, Tuberculosis.

Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model

A. Schipani, G. Davies, Yanmin Hu, 2016, Antimicrobial Agents and Chemotherapy.

Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin

M. Anjum, Yanmin Hu, A. Coates, 2014, Front. Microbiol..

Comparison of the sterilising activities of the nitroimidazopyran PA-824 and moxifloxacin against persisting Mycobacterium tuberculosis.

D. Mitchison, Yanmin Hu, A. Coates, 2008, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Novel approaches to developing new antibiotics for bacterial infections

A. Coates, Yanmin Hu, A. Coates, 2007, British journal of pharmacology.

Novel classes of antibiotics or more of the same?

A. Coates, Yanmin Hu, Gerry Halls, 2011, British journal of pharmacology.

HspX knock-out in Mycobacterium tuberculosis leads to shorter antibiotic treatment and lower relapse rate in a mouse model--a potential novel therapeutic target.

K. Oravcová, S. Gillespie, D. Mitchison, 2015, Tuberculosis.

A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis

Yanmin Hu, A. Coates, U. Simonsson, 2020, Journal of Pharmacokinetics and Pharmacodynamics.

A Mycobacterium tuberculosis Mutant Lacking the groEL Homologue cpn60.1 Is Viable but Fails To Induce an Inflammatory Response in Animal Models of Infection

G. Besra, P. Lund, B. Henderson, 2008, Infection and Immunity.