Ai-lin Liu

发表

An investigation of changes in water quality throughout the drinking water production/distribution chain using toxicological and fluorescence analyses.

Xuan Ma, Xue Han, Xin Ji, 2020, Journal of environmental sciences.

[Network pharmacology study of effective constituents of traditional Chinese medicine for Alzheimer’s disease treatment].

G. Du, Ai-lin Liu, Zhe Wang, 2016, Yao xue xue bao = Acta pharmaceutica Sinica.

DL0410 ameliorates cognitive deficits in APP/PS1 transgenic mice by promoting synaptic transmission and reducing neuronal loss

G. Du, W. Zhou, Ai-lin Liu, 2019, Acta Pharmacologica Sinica.

Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI

Zhongfeng Wang, Ai-lin Liu, Xin Huang, 2019, EBioMedicine.

Screening of cytochrome P450 3A4 inhibitors via in silico and in vitro approaches

G. Du, Ai-lin Liu, Xiaocong Pang, 2018, RSC advances.

Anti-influenza virus activities of flavonoids from the medicinal plant Elsholtzia rugulosa.

G. Du, Yitao Wang, S. Lee, 2008, Planta medica.

DL0410 Ameliorates Memory and Cognitive Impairments Induced by Scopolamine via Increasing Cholinergic Neurotransmission in Mice

G. Du, W. Zhou, Ai-lin Liu, 2017, Molecules.

Actinomycin D synergistically enhances the cytotoxicity of CDDP on KB cells by activating P53 via decreasing P53–MDM2 complex

Ai-lin Liu, Jinhua Wang, Guanhua Du, 2017, Journal of Asian natural products research.

Investigating the performance of three modified activated sludge processes treating municipal wastewater in organic pollutants removal and toxicity reduction.

W. Lu, Xue Han, Fei Tang, 2018, Ecotoxicology and environmental safety.

Competing Endogenous RNA and Coexpression Network Analysis for Identification of Potential Biomarkers and Therapeutics in association with Metastasis Risk and Progression of Prostate Cancer

Ai-lin Liu, Wan Li, Jinhua Wang, 2019, Oxidative medicine and cellular longevity.

Molecular Modeling on Berberine Derivatives toward BuChE: An Integrated Study with Quantitative Structure–Activity Relationships Models, Molecular Docking, and Molecular Dynamics Simulations

C. Li, Li Gao, Qi Wang, 2016, Chemical biology & drug design.

Levofloxacin-based carbon dots to enhance antibacterial activities and combat antibiotic resistance

Ai-lin Liu, Yun Lei, Lin Huang, 2021, Carbon.

Ameliorative effects of baicalein in MPTP-induced mouse model of Parkinson's disease: A microarray study

X. Qin, Jiansong Fang, Li Gao, 2015, Pharmacology Biochemistry and Behavior.

Identification of multi-target anti-cancer agents from TCM formula by in silico prediction and in vitro validation.

Ai-lin Liu, De Kang, Lv-jie Xu, 2022, Chinese journal of natural medicines.

Discovery of VEGFR2 inhibitors by integrating naïve Bayesian classification, molecular docking and drug screening approaches

G. Du, Ai-lin Liu, Jinhua Wang, 2018, RSC advances.

DL0410 ameliorates cognitive disorder in SAMP8 mice by promoting mitochondrial dynamics and the NMDAR-CREB-BDNF pathway

G. Du, W. Zhou, Ai-lin Liu, 2020, Acta Pharmacologica Sinica.

Drinking-Water Disinfection By-products and Semen Quality: A Cross-Sectional Study in China

Yi-Xin Wang, Q. Zeng, Min Li, 2014, Environmental health perspectives.

Evaluation of exposure to trihalomethanes in tap water and semen quality: a prospective study in Wuhan, China.

Q. Zeng, Min Li, Yu-Feng Li, 2014, Reproductive toxicology.

In Vivo Angiogenesis Screening and Mechanism of Action of Novel Tanshinone Derivatives Produced by One-Pot Combinatorial Modification of Natural Tanshinone Mixture from Salvia Miltiorrhiza

W. Ye, Ai-lin Liu, Shang Li, 2014, PloS one.

(-)-Epigallocatechin-3-gallate attenuates the toxicity of methylmercury in Caenorhabditis elegans by activating SKN-1.

W. Lu, Xue Han, Xin Ji, 2019, Chemico-biological interactions.

Significant positive correlation of plasma BPDE-albumin adducts to urinary 1-hydroxypyrene in coke oven workers.

Ai-lin Liu, Tang-chun Wu, Yong-Yi Bi, 2007, Biomedical and environmental sciences : BES.

Design, Synthesis, and Biological Evaluation of a New Series of Biphenyl/Bibenzyl Derivatives Functioning as Dual Inhibitors of Acetylcholinesterase and Butyrylcholinesterase

G. Du, Dong-mei Wang, Song Wu, 2017, Molecules.

DL0410 can reverse cognitive impairment, synaptic loss and reduce plaque load in APP/PS1 transgenic mice

Jiansong Fang, G. Du, Dong-mei Wang, 2015, Pharmacology Biochemistry and Behavior.

DNA damage and oxidative stress in human liver cell L‐02 caused by surface water extracts during drinking water treatment in a waterworks in China

W. Lu, Ai-lin Liu, B. Jin, 2009, Environmental and molecular mutagenesis.

In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: identifying sinensetin as a novel antiangiogenesis agent.

G. Du, Ping Liu, Ai-lin Liu, 2012, Molecular nutrition & food research.

DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway

W. Zhou, G. Du, Song Wu, 2016, Acta Pharmacologica Sinica.

Spatial and temporal evaluations of estrogenic activity in tap water served by a water plant in Wuhan, China.

Q. Zeng, W. Lu, Ai-lin Liu, 2013, Ecotoxicology and environmental safety.

Chlorinated river and lake water extract caused oxidative damage, DNA migration and cytotoxicity in human cells.

V. Mersch-Sundermann, W. Lu, Jing Yuan, 2005, International journal of hygiene and environmental health.

Oxidative stress and cell‐cycle change induced by coexposed PCB126 and benzo(a) pyrene to human hepatoma (HepG2) cells

W. Lu, Ai-lin Liu, Xue-min Chen, 2012, Environmental toxicology.

Comparison of DNA damage in human-derived hepatoma line (HepG2) exposed to the fifteen drinking water disinfection byproducts using the single cell gel electrophoresis assay.

Q. Zeng, W. Lu, Ai-lin Liu, 2012, Mutation research.

Effects of P-Glycoprotein on the Transport of DL0410, a Potential Multifunctional Anti-Alzheimer Agent

G. Du, Song Wu, Ai-lin Liu, 2017, Molecules.

Semen phthalate metabolites, spermatozoa apoptosis, and DNA damage: a cross-sectional study in China.

Yi-Xin Wang, Q. Zeng, Ling You, 2015, Environmental science & technology.

Baseline blood trihalomethanes, semen parameters and serum total testosterone: a cross-sectional study in China.

Q. Zeng, Min Li, Yu-Feng Li, 2013, Environment international.

Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.

G. Du, Yitao Wang, Ai-lin Liu, 2008, Bioorganic & medicinal chemistry.

Assessment of the cytotoxicity and genotoxicity of haloacetic acids using microplate-based cytotoxicity test and CHO/HGPRT gene mutation assay.

Wei Wei, W. Lu, Ai-lin Liu, 2010, Mutation research.

Bioassay of ferulic acid derivatives as influenza neuraminidase inhibitors

Ai-lin Liu, Lv-jie Xu, Yun Chen, 2020, Archiv der Pharmazie.

Evaluation of Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors as Potential Anti-Alzheimer’s Disease Agents Using Pharmacophore, 3D-QSAR and Molecular Docking Approaches

G. Du, Song Wu, Ai-lin Liu, 2017, Molecules.

Active Constituents in Danshen and Their Pharmacological Actions

Ping Chen, G. Du, Yitao Wang, 2015 .

Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheimer's disease.

Jiansong Fang, G. Du, Ai-lin Liu, 2018, Chinese journal of natural medicines.

Antiviral Properties of Phytochemicals

G. Du, Ai-lin Liu, 2012, Dietary Phytochemicals and Microbes.

Associations of urinary metal concentrations and circulating testosterone in Chinese men.

Bin Zhou, Yi-Xin Wang, Q. Zeng, 2013, Reproductive toxicology.

Synthesis and Anticancer Activity of Novel Thiazole-5-Carboxamide Derivatives

Zhengming Li, Ai-lin Liu, Xingping Liu, 2016 .

Design, synthesis and biological evaluation of honokiol derivatives as influenza neuraminidase inhibitors

G. Du, Ai-lin Liu, Wenwen Lian, 2019, Journal of Asian natural products research.

Novel Alkaloids from the Roots of Stemona sessilifolia

G. Du, Ai-lin Liu, Zhi-hong Li, 2007, Chemistry & biodiversity.

Stemoninine-type alkaloids from the roots of Stemona sessilifolia

G. Du, Ai-lin Liu, Zhi-hong Li, 2008, Journal of Asian natural products research.

A New Alkaloid from Stemona sessilifolia

G. Du, Ai-lin Liu, Zhi-hong Li, 2007 .

In vitro Anti-Influenza Viral Activities of Constituents from Caesalpinia sappan

G. Du, Yitao Wang, Ai-lin Liu, 2009, Planta medica.

Synthesis and biological activity of novel anthranilic diamides containing N-substituted arylmethylene moieties

Li-xia Xiong, Zhengming Li, Ai-lin Liu, 2013, Chemical Research in Chinese Universities.

Isolation, structural characterization and neuraminidase inhibitory activities of polyphenolic constituents from Flos caryophylli

G. Du, Ai-lin Liu, Hui Xu, 2017 .

Chemical constituents of the whole plant of Elsholtzia rugulosa

G. Du, Ai-lin Liu, Bo Liu, 2012, Journal of Asian natural products research.

Integration of virtual screening with high-throughput screening for the identification of novel Rho-kinase I inhibitors.

Guan-Hua Du, Ai-Lin Liu, Lian-Hua Fang, 2010, Journal of biotechnology.

Antioxidant, Anti-Inflammatory and Anti-Influenza Properties of Components from Chaenomeles speciosa

G. Du, Ai-lin Liu, Yong‐Xian Cheng, 2010, Molecules.

In vitro Antiviral Effects and 3D QSAR Study of Resveratrol Derivatives as Potent Inhibitors of Influenza H1N1 Neuraminidase

C. Li, Jiansong Fang, G. Du, 2015, Chemical biology & drug design.

Discovery of Influenza A virus neuraminidase inhibitors using support vector machine and Naïve Bayesian models

Xiaocong Pang, Wenwen Lian, Guan-Hua Du, 2015, Molecular Diversity.

Transgene is specifically and functionally expressed in retinal inhibitory interneurons in the VGAT-ChR2-EYFP mouse

Xiong-Li Yang, Y. Zhong, W. Zhou, 2017, Neuroscience.

In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine

Chuipu Cai, Jingwei Zhou, Jiansong Fang, 2019, Front. Pharmacol..

Detection of genotoxic effects of drinking water disinfection by-products using Vicia faba bioassay

W. Lu, Xue Han, Ai-lin Liu, 2016, Environmental Science and Pollution Research.

Bromodichloromethane induces cell proliferation in different tissues of male F344 rats by suppression of E-cadherin expression via hypermethylation or transcriptional activation of c-myc and cyclin D1.

W. Lu, Ai-lin Liu, Shunchang Zhou, 2013, Toxicology letters.

PCB126 enhanced the genotoxicity of BaP in HepG2 cells by modulating metabolic enzyme and DNA repair activities.

W. Lu, Ai-lin Liu, Xue-min Chen, 2009, Toxicology letters.

Effect of PCB153 on BaP-induced genotoxicity in HepG2 cells via modulation of metabolic enzymes.

W. Lu, Ai-lin Liu, Xue-min Chen, 2009, Mutation research.

In vitro anti-influenza viral activities of stilbenoids from the lianas of Gnetum pendulum.

G. Du, Yitao Wang, Ai-lin Liu, 2010, Planta medica.

Elevated Levels of Urinary 8-Hydroxy-2′-deoxyguanosine, Lymphocytic Micronuclei, and Serum Glutathione S-Transferase in Workers Exposed to Coke Oven Emissions

W. Lu, Jing Yuan, Ai-lin Liu, 2005, Environmental health perspectives.

nGnG Amacrine Cells and Brn3b-negative M1 ipRGCs are Specifically Labeled in the ChAT-ChR2-EYFP Mouse

Xiong-Li Yang, Y. Zhong, Ai-lin Liu, 2020, Investigative ophthalmology & visual science.

Discovery of the neuroprotective effects of alvespimycin by computational prioritization of potential anti‐parkinson agents

Guan-Hua Du, Ai-Lin Liu, Jiansong Fang, 2014, The FEBS journal.

The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer's Disease

G. Du, Ai-lin Liu, Jinhua Wang, 2017, BioMed research international.

Screening for Neuraminidase Inhibitory Activity in Traditional Chinese Medicines Used to Treat Influenza

Ai-lin Liu, Lin-Fang Huang, Xiao-wei Xu, 2016, Molecules.

Toxicity of 2,6-dichloro-1,4-benzoquinone and five regulated drinking water disinfection by-products for the Caenorhabditis elegans nematode.

W. Lu, Xue Han, Ai-lin Liu, 2017, Journal of hazardous materials.

Inhibition of acetylcholinesterase by two genistein derivatives: kinetic analysis, molecular docking and molecular dynamics simulation

Chao Li, Ranyao Yang, Guan-Hua Du, 2014, Acta pharmaceutica Sinica. B.

Comparative cytotoxic and genotoxic potential of 13 drinking water disinfection by-products using a microplate-based cytotoxicity assay and a developed SOS/umu assay.

W. Lu, Ai-lin Liu, Shao-Hui Zhang, 2015, Mutagenesis.

Predictors of urinary trichloroacetic acid and baseline blood trihalomethanes concentrations among men in China.

Ai-Lin Liu, Yi-Xin Wang, Ling You, 2014, The Science of the total environment.

Relaxin attenuates silica-induced pulmonary fibrosis by regulating collagen type I and MMP-2.

Ai-Lin Liu, W. Lu, Ai-lin Liu, 2013, International immunopharmacology.

[Active neuraminidase constituents of Polygonum cuspidatum against influenza A(H1N1) influenza virus].

G. Du, Ai-lin Liu, Wei-wen Chen, 2012, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Urinary trichloroacetic acid levels and semen quality: a hospital-based cross-sectional study in Wuhan, China.

Yu-Feng Li, W. Lu, Ai-lin Liu, 2011, Environmental research.

Network-Based Identification and Experimental Validation of Drug Candidates Toward SARS-CoV-2 via Targeting Virus–Host Interactome

Chuipu Cai, Qihui Wu, Fei Ye, 2021, Frontiers in Genetics.

[Research advance in the drug target prediction based on chemoinformatics].

Guan-hua Du, Jian-song Fang, Ai-lin Liu, 2014, Yao xue xue bao = Acta pharmaceutica Sinica.

DNA damage caused by extracts of chlorinated drinking water in human derived liver cells (HepG2).

V. Mersch-Sundermann, W. Lu, Ai-lin Liu, 2004, Toxicology.

Discovery of neuroprotective compounds by machine learning approaches

Qi Wang, Chao Li, Rong Yan, 2016 .

Discovery of Influenza A virus neuraminidase inhibitors using support vector machine and Naïve Bayesian models

G. Du, Ai-lin Liu, Xiaocong Pang, 2016, Molecular Diversity.

Synthesis of Novel 1,2,4‐Triazole‐3‐thione Derivatives as Influenza Neuraminidase Inhibitors

Ai-lin Liu, Hao Jia, A. Hu, 2019, Journal of Heterocyclic Chemistry.

3D QSAR and docking study of flavone derivatives as potent inhibitors of influenza H1N1 virus neuraminidase.

Guan-Hua Du, Ai-Lin Liu, Li Gao, 2011, Bioorganic & medicinal chemistry letters.

Optic nerve crush modulates refractive development of the C57BL/6 mouse by changing multiple ocular dimensions

Xiong-Li Yang, Y. Zhong, J. Qu, 2020, Brain Research.

Predictions of BuChE Inhibitors Using Support Vector Machine and Naive Bayesian Classification Techniques in Drug Discovery

Jiansong Fang, Li Gao, Dan Zhou, 2013, J. Chem. Inf. Model..

Evaluation of genotoxic effects caused by extracts of chlorinated drinking water using a combination of three different bioassays.

W. Lu, Ai-lin Liu, Xinyi Wang, 2015, Journal of hazardous materials.

A concise synthesis of (±)-7-O-galloyltricetiflavan

Song Wu, Ai-lin Liu, Wenxuan Zhang, 2018, RSC advances.

AlzhCPI: A knowledge base for predicting chemical-protein interactions towards Alzheimer’s disease

Qi Wang, Jiansong Fang, Ling Wang, 2017, PloS one.

Consensus models for CDK5 inhibitors in silico and their application to inhibitor discovery

Li Gao, G. Du, Ai-lin Liu, 2015, Molecular Diversity.

Discovery of Multitarget-Directed Ligands against Alzheimer's Disease through Systematic Prediction of Chemical-Protein Interactions

Rui Liu, Chao Li, Jiansong Fang, 2015, J. Chem. Inf. Model..

Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches

G. Du, Ai-lin Liu, Jinhua Wang, 2018, Oxidative medicine and cellular longevity.

In Silico Prediction and Bioactivity Evaluation of Chemical Ingredients Against Influenza A Virus From Isatis tinctoria L

C. Cai, Qi Wang, Xiaoyi Liu, 2021, Frontiers in Pharmacology.

[Analysis of serum glutathione S-transferase and urinary 8-hydroxy-2-deoxyguanosine in coke oven workers].

W. Lu, Ai-lin Liu, W. Lu, 2005, Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.

In silico Target Fishing for the Potential Targets and Molecular Mechanisms of Baicalein as an Antiparkinsonian Agent: Discovery of the Protective Effects on NMDA Receptor‐Mediated Neurotoxicity

Jiansong Fang, Li Gao, G. Du, 2013, Chemical biology & drug design.

Arylazolyl(azinyl)thioacetanilide. Part 9: Synthesis and biological investigation of thiazolylthioacetamides derivatives as a novel class of potential antiviral agents

C. Pannecouque, L. Naesens, P. Zhan, 2012, Archives of pharmacal research.

Water Pollution and Health Impact in China: A Mini Review

W. Lu, Ai-lin Liu, Shaohua Xie, 2008 .

[Network pharmacology: new guidelines for drug discovery].

Guan-hua Du, Ai-lin Liu, G. Du, 2010, Yao xue xue bao = Acta pharmaceutica Sinica.

Anti-influenza effect and action mechanisms of the chemical constituent gallocatechin-7-gallate from Pithecellobium clypearia Benth

G. Du, Ai-lin Liu, Xiaocong Pang, 2018, Acta Pharmacologica Sinica.

Drug Discovery of Host CLK1 Inhibitors for Influenza Treatment

C. Li, Jiansong Fang, G. Du, 2015, Molecules.

The Protective Effect of 3-Deoxysappanchalcone on In Vitro Influenza Virus-induced Apoptosis and Inflammation

G. Du, Yitao Wang, Ai-lin Liu, 2012, Planta Medica.

Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation.

X. Chen, Ai-lin Liu, Hai-bo Liu, 2023, Food & function.

[Development of HTS model on SERT inhibitors combined biological screening model with HTVS].

G. Du, Ai-lin Liu, Jian-song Fang, 2015, Yao xue xue bao = Acta pharmaceutica Sinica.

Novel Alkaloids from the Roots of Stemona sessilifolia

G. Du, Ai-lin Liu, Zhi-hong Li, 2007, Chemistry & biodiversity.