P. Isackson

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Cell‐specific expression of type II calcium/calmodulin‐dependent protein kinase isoforms and glutamate receptors in normal and visually deprived lateral geniculate nucleus of monkeys

E. G. Jones, T. Hashikawa, E. Jones, 1998, The Journal of comparative neurology.

Inhibitors of Urokinase and Thrombin in Cultured Neural Cells

S. Wagner, J. Mimuro, D. Loskutoff, 1991, Journal of neurochemistry.

Seizures increase basic fibroblast growth factor mRNA in adult rat forebrain neurons and glia.

C. Gall, P. Isackson, P. J. Isackson, 1994, Brain research. Molecular brain research.

Seizure-induced alterations of plasma membrane calcium ATPase isoforms 1, 2 and 3 mRNA and protein in rat hippocampus.

K. Murray, E. Strehler, P. Isackson, 1997, Brain research. Molecular brain research.

The alpha-subunit of mouse 7 S nerve growth factor is an inactive serine protease.

R. Bradshaw, P. Isackson, 1984, The Journal of biological chemistry.

Substrate specificities of growth factor associated kallikreins of the mouse submandibular gland.

M. Blaber, R. Bradshaw, P. Isackson, 1989, Biochemistry.

Mouse 7S nerve growth factor: complete sequence of a cDNA coding for the alpha-subunit precursor and its relationship to serine proteases.

A. Ullrich, R. Bradshaw, P. Isackson, 1984, Biochemistry.

Seizures and the regulation of neurotrophic factor and neuropeptide gene expression in brain.

M. Bundman, J. Lauterborn, C. Gall, 1991, Epilepsy research. Supplement.

Association of SLCO1B1 c.521T>C (rs4149056) with discontinuation of atorvastatin due to statin-associated muscle symptoms

H. Ochs-Balcom, J. Luzum, G. Vladutiu, 2020, Pharmacogenetics and genomics.

Expression of the alpha subunit of 7S nerve growth factor in the mouse submandibular gland

R. Bradshaw, P. Isackson, S. Nisco, 1987, Neurochemical Research.

Nervous System-Specific Expression of a Novel Serine Protease: Regulation in the Adult Rat Spinal Cord by Excitotoxic Injury

P. Isackson, I. Scarisbrick, P. J. Isackson, 1997, The Journal of Neuroscience.

Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons

C. Gall, K. Seroogy, P. Isackson, 1992, Molecular and Cellular Neuroscience.

Seizure-Induced Increases in NGF mRNA Exhibit Different Time Courses across Forebrain Regions and Are Biphasic in Hippocampus

J. Lauterborn, C. Gall, P. Isackson, 1994, Experimental Neurology.

Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus.

F. Poulsen, J. Lauterborn, C. Gall, 1998, Brain research. Molecular brain research.

Distinct promoters regulate tissue‐specific and differential expression of kallikrein 6 in CNS demyelinating disease

M. Blaber, M. Rodriguez, P. Isackson, 2004, Journal of neurochemistry.

RYR1 and CACNA1S genetic variants identified with statin-associated muscle symptoms.

J. Bard, G. Vladutiu, P. Isackson, 2018, Pharmacogenomics.

MSP, a trypsin‐like serine protease, is abundantly expressed in the human nervous system

Moses Rodriguez, A. Windebank, M. Rodriguez, 2001, The Journal of comparative neurology.

Preferential expression of myelencephalon‐specific protease by oligodendrocytes of the adult rat spinal cord white matter

Moses Rodriguez, A. Windebank, M. Blaber, 2000, Glia.

The structure of murine 7S nerve growth factor: implications for biosynthesis.

A. Ullrich, R. Bradshaw, P. Isackson, 1985, The International journal of neuroscience.

Isolation and Sequence of a cDNA Clone of β‐Nerve Growth Factor from the Guinea Pig Prostate Gland

R. Bradshaw, D. Fisher, P. Isackson, 1989, Journal of neurochemistry.

Coenzyme Q10 supplementation for the treatment of statin-associated muscle symptoms.

H. Ochs-Balcom, J. Luzum, G. Vladutiu, 2022, Future cardiology.

Acidic fibroblast growth factor mRNA is expressed by basal forebrain and striatal cholinergic neurons

J. Bizon, J. Lauterborn, C. Gall, 1996, The Journal of comparative neurology.

Influence of nonhistone chromatin protein HMG-1 on the enzymatic digestion of purified DNA.

G. Reeck, J. Fishback, P. Isackson, 1982, Nucleic acids research.

Nonhistone chromatin proteins HMG-14 and HMG-17 bind preferentially to single-stranded DNA.

G. Reeck, P. Isackson, 1981, Nucleic acids research.

Endothelin increases atrial natriuretic peptide production in cultured rat diencephalic neurons.

E. Levin, P. Isackson, P. J. Isackson, 1991, Endocrinology.

Ionic interactions between proteins in nonequilibrium pH gradient electrophoresis: histones affect the migration of high mobility group nonhistone chromatin proteins.

G. Reeck, R. Tweten, P. Isackson, 1983, Analytical biochemistry.

SLCO1B1 variants and statin-induced myopathy.

G. Vladutiu, P. Isackson, 2009, The New England journal of medicine.

High mobility group chromosomal proteins isolated from muclei and cytosol of cultured hepatoma cells are similar.

M. Bustin, G. Reeck, D. Bidney, 1980, Biochemistry.

Metabolic Myopathies Discovered During Investigations of Statin Myopathy

M. Tarnopolsky, G. Vladutiu, P. Isackson, 2008, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

Identification of a polymorphism in the human neurotensin receptor gene.

M. Watson, P. Isackson, E. Richelson, 1993, Mayo Clinic proceedings.

Two-dimensional gel electrophoresis of nonhistone chromatin proteins with nonequilibrium pH gradient electrophoresis as the first dimension.

G. Reeck, P. Isackson, P. J. Isackson, 1982, Analytical biochemistry.

Comparison of mammalian, chicken and Xenopus brain‐derived neurotrophic factor coding sequences

M. Huntsman, P. Isackson, P. J. Isackson, 1991, FEBS letters.

Activity-dependent regulation of gene expression in adult monkey visual cortex.

S. Hendry, E. Jones, D. Benson, 1990, Cold Spring Harbor symposia on quantitative biology.

Haloperidol but Not Clozapine Increases Neurotensin Receptor mRNA Levels in Rat Substantia Nigra

K. Murray, M. Watson, P. Isackson, 1993, Journal of neurochemistry.

Ryanodine Receptor Type 1 Gene Variants in the Malignant Hyperthermia-Susceptible Population of the United States

B. Brandom, G. Vladutiu, Cynthia A. Wong, 2013, Anesthesia and analgesia.

Lamina-specific expression and activity-dependent regulation of seven GABAA receptor subunit mRNAs in monkey visual cortex

M. Huntsman, P. Isackson, M. Huntsman, 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Stimulus-dependent, reciprocal up- and downregulation of glutamic acid decarboxylase and Ca2+/calmodulin-dependent protein kinase II gene expression in rat cerebral cortex

E. G. Jones, P. Isackson, F. Liang, 1996, Experimental Brain Research.

Expression of glutamic acid decarboxylase mRNA in normal and monocularly deprived cat visual cortex.

S. Hendry, D. Benson, P. Isackson, 1989, Brain research. Molecular brain research.

Seizures, neuropeptide regulation, and mRNA expression in the hippocampus.

J. Lauterborn, C. Gall, P. Isackson, 1990, Progress in brain research.

Differential gene expression for glutamic acid decarboxylase and type II calcium-calmodulin-dependent protein kinase in basal ganglia, thalamus, and hypothalamus of the monkey

S. Hendry, D. Benson, D. Benson, 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Differential effects of monocular deprivation on glutamic acid decarboxylase and type II calcium-calmodulin-dependent protein kinase gene expression in the adult monkey visual cortex [published erratum appears in J Neurosci 1991 May;11(5):following Table of Contents]

C. Gall, D. Benson, D. Benson, 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease

E. Jones, C. Gall, K. Murray, 1994, Neuroscience.

A metabotropic glutamate receptor agonist regulates neurotrophin messenger RNA in rat forebrain

P. Wood, K. Murray, P. Isackson, 1996, Neuroscience.

Dendritic localization of type II calcium calmodulin-dependent protein kinase mRNA in normal and reinnervated rat hippocampus

D. L. Benson, C. Gall, D. Benson, 1992, Neuroscience.

Contrasting patterns in the localization of glutamic acid decarboxylase and Ca2+ /calmodulin protein kinase gene expression in the rat centrat nervous system

C. Gall, D. Benson, P. Isackson, 1992, Neuroscience.

Altered mRNA expression for brain‐derived neurotrophic factor and type II calcium/Calmodulin‐dependent protein kinase in the hippocampus of patients with intractable temporal lobe epilepsy

S. Roper, M. King, K. Murray, 2000, The Journal of comparative neurology.

Attenuation of the seizure‐induced expression of BDNF mRNA in adult rat brain by an inhibitor of calcium/calmodulin‐dependent protein kinases

C. Gall, K. Murray, P. Isackson, 1998, The European journal of neuroscience.

Carnitine Palmitoyl Transferase Deficiency in a University Immunology Practice

P. Isackson, J. Ambrus, P. J. Isackson, 2020, Current Rheumatology Reports.

BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF

M. Huntsman, C. Gall, K. Murray, 1991, Neuron.

In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cord.

J. Lauterborn, C. Gall, P. Isackson, 1993, Brain research. Molecular brain research.

Myoadenylate deaminase deficiency caused by alternative splicing due to a novel intronic mutation in the AMPD1 gene.

C. Harding, G. Vladutiu, P. Isackson, 2005, Molecular genetics and metabolism.

Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus.

C. Gall, K. Murray, P. Isackson, 1991, Brain research. Molecular brain research.

Identification of 16 new disease-causing mutations in the CPT2 gene resulting in carnitine palmitoyltransferase II deficiency.

M. Bennett, G. Vladutiu, P. Isackson, 2006, Molecular genetics and metabolism.

Role of glandular kallikreins as growth factor processing enzymes: Structural and evolutionary considerations

R. Bradshaw, P. Isackson, J. Dunbar, 1987, Journal of cellular biochemistry.

Dopaminergic neurons in rat ventral midbrain express brain‐derived neurotrophic factor and neurotrophin‐3 mRNAs

C. Gall, K. Seroogy, P. Isackson, 1994, The Journal of comparative neurology.

Genetic risk for malignant hyperthermia in non-anesthesia-induced myopathies.

Beth Cobb, J. Harley, K. Kaufman, 2011, Molecular genetics and metabolism.

Developmental expression of brain derived neurotrophic factor mRNA by neurons of fetal and adult monkey prefrontal cortex.

D. Benson, G. W. Huntley, P. Isackson, 1992, Brain research. Developmental brain research.

N-methyl-d-aspartate receptor dependent transcriptional regulation of two calcium/calmodulin-dependent protein kinase type II isoforms in rodent cerebral cortex

K. Murray, P. Isackson, P. J. Isackson, 2003, Neuroscience.

Nerve growth factor: mechanism of action.

R. Bradshaw, P. Isackson, C. Morgan, 1984, Symposium on Fundamental Cancer Research.

Genetic risk factors associated with lipid‐lowering drug‐induced myopathies

Zachary Simmons, Mark Tarnopolsky, M. Tarnopolsky, 2006, Muscle & nerve.

Differential Effects of Protein Synthesis Inhibition on the Activity-Dependent Expression of BDNF Transcripts: Evidence for Immediate-Early Gene Responses from Specific Promoters

J. Lauterborn, C. Gall, P. Isackson, 1996, The Journal of Neuroscience.

Limbic seizures increase neuronal production of messenger RNA for nerve growth factor.

C. Gall, P. Isackson, C M Gall, 1989, Science.

Domain structure in high molecular weight high mobility group nonhistone chromatin proteins

G. Reeck, D. Teller, P. Isackson, 1982, Nature.

Statin therapy depresses total body fat oxidation in the absence of genetic limitations to fat oxidation

D. Pendergast, N. Fisher, G. Vladutiu, 2007, Journal of Inherited Metabolic Disease.

Dominant negative mutations in the Tn10 tet repressor: evidence for use of the conserved helix-turn-helix motif in DNA binding.

P. Isackson, K. Bertrand, 1985, Proceedings of the National Academy of Sciences of the United States of America.

CPT2 gene mutations resulting in lethal neonatal or severe infantile carnitine palmitoyltransferase II deficiency.

V. Sutton, W. Nyhan, M. Bennett, 2008, Molecular genetics and metabolism.

Preferential affinity of high molecular weight high mobility group non-histone chromatin proteins for single-stranded DNA.

G. Reeck, J. Fishback, D. Bidney, 1979, The Journal of biological chemistry.

Decreased expression of the alpha subunit of Ca2+/ calmodulin-dependent protein kinase type II mRNA in the adult rat CNS following recurrent limbic seizures.

C. Gall, D. Benson, K. Murray, 1995, Brain research. Molecular brain research.

Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease.

C. Cotman, D. Gurwitz, J. Geddes, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The messenger RNA encoding VGF, a neuronal peptide precursor, is rapidly regulated in the rat central nervous system by neuronal activity, seizure and lesion

K. Murray, P. Isackson, T. McNeill, 1997, Neuroscience.

In situ hybridization reveals VIP precursor mRNA-containing neurons in monkey and rat neocortex.

D. Benson, P. Isackson, P. J. Isackson, 1991, Brain research. Molecular brain research.

Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript.

C. Cotman, N. Berchtold, P. Isackson, 1999, Brain research. Molecular brain research.

Production of HMG-3 by limited trypsin digestion of purified high-mobility-group nonhistone chromatin proteins.

G. Reeck, J. Beaudoin, M. Hermodson, 1983, Biochimica et biophysica acta.

Removal of degradation products from calf thymus high mobility group non-histone chromatin proteins by chromatography on immobilized double-stranded DNA.

G. Reeck, P. Isackson, 1982, Biochimica et biophysica acta.

Isolation and separation of chicken erythrocyte high mobility group non‐histone chromatin proteins by chromatography on phosphocellulose

G. Reeck, P. Isackson, P. J. Isackson, 1980, FEBS letters.

Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus.

C. Cotman, N. Berchtold, P. Isackson, 1998, Brain research. Molecular brain research.

GATM polymorphism associated with the risk for statin-induced myopathy does not replicate in case-control analysis of 715 dyslipidemic individuals.

M. Medina, H. Ochs-Balcom, G. Vladutiu, 2015, Cell metabolism.

Epidermal growth factor binding protein: identification of a different protein.

E. Shooter, M. Blaber, R. Bradshaw, 1987, Biochemistry.

Long‐term alterations in growth factor mRNA expression following seizures

A. Windebank, P. Isackson, V. B. Garcia, 1997, Neuroreport.

Nerve growth factor mRNA‐containing cells are distributed within regions of cholinergic neurons in the rat basal forebrain

J. Lauterborn, C. Gall, P. Isackson, 1991, The Journal of comparative neurology.

Trophic factor response to neuronal stimuli or injury

P. Isackson, P. J. Isackson, 1995, Current Opinion in Neurobiology.

Induction of nerve growth factor and basic fibroblast growth factor mRNA following clenbuterol: Contrasting anatomical and cellular localization

P. Isackson, P. Follesa, I. Mocchetti, 1995, Experimental Neurology.

Synthetic chimeras of mouse growth factor‐associated glandular kallikreins. I. Kinetic properties

M. Blaber, R. Bradshaw, P. Isackson, 1993, Protein science : a publication of the Protein Society.

Synthetic chimeras of mouse growth factor‐associated glandular kallikreins. II. Growth factor binding properties

M. Blaber, R. Bradshaw, H. Holden, 1993, Protein science : a publication of the Protein Society.

The characterization of recombinant mouse glandular kallikreins from E. coli

M. Blaber, R. Bradshaw, P. Isackson, 1990, Proteins.

A novel mutation in the PYGM gene in a family with pseudo-dominant transmission of McArdle disease.

M. Tarnopolsky, G. Vladutiu, P. Isackson, 2005, Molecular genetics and metabolism.

Nerve growth factor mRNA is expressed by GABAergic neurons in rat hippocampus.

J. Lauterborn, C. Gall, P. Isackson, 1993, Neuroreport.

Cellular Localization of NGF and NT-3 mRNAs in Postnatal Rat Forebrain

J. Lauterborn, C. Gall, P. Isackson, 1994, Molecular and Cellular Neuroscience.

A complete cDNA sequence for the major epidermal growth factor binding protein in the male mouse submandibular gland.

M. Blaber, R. Bradshaw, P. Isackson, 1987, Biochemistry.

Organization, sequence and functional analysis of a mouse BDNF promoter.

P. Isackson, P. J. Isackson, V. Hayes, 1997, Brain research. Molecular brain research.

Differential Expression of Brain-Derived Neurotrophic Factor, Neurotrophin-3, and Neurotrophin-4/5 in the Adult Rat Spinal Cord: Regulation by the Glutamate Receptor Agonist Kainic Acid

A. Windebank, P. Isackson, I. Scarisbrick, 1999, The Journal of Neuroscience.

Comparison of the salt dissociations of high molecular weight HMG non‐histone chromatin proteins from double‐stranded DNA and from chromatin

G. Reeck, P. Isackson, Paul J. Isackson, 1981, FEBS letters.

Association of common variants in the human eyes shut ortholog (EYS) with statin‐induced myopathy: Evidence for additional functions of EYS

M. Tarnopolsky, Beth Cobb, J. Harley, 2011, Muscle & nerve.

Novel mutations in the gene encoding very long‐chain acyl‐CoA dehydrogenase identified in patients with partial carnitine palmitoyltransferase ii deficiency

G. Vladutiu, P. Isackson, K. Hostetler, 2013, Muscle & nerve.

Glucocorticoids differentially increase nerve growth factor and basic fibroblast growth factor expression in the rat brain

A. Colangelo, P. Isackson, I. Mocchetti, 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.