P. Clapés

M. Infante, M. Vinardell, M. Mitjans, 2008, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Influence of the contact model and support characteristics on the partition constant for kinetically controlled synthesis of peptides

J. Mata-Álvarez, I. Haro, J. García-Antón, 2007 .

Continuous enzymatic synthesis of Z‐kyotorphin amide in an enzyme‐immobilized fixed‐bed reactor

J. Mata-Álvarez, J. García-Antón, P. Clapés, 2007 .

Neoglycopeptide Synthesis and Purification in Multi‐gram Scale: Preparation of O‐(2,3,4,6‐tetra‐O‐acetyl‐β‐D‐galactopyranosyl)‐Nα‐fluoren‐9‐yl‐methoxycarbonyl‐hydroxyproline and Its Use in the Pilot‐scale Synthesis of the Potent Analgesic Glycopeptide O1.5‐β‐D‐galactopyranosyl[DMet2, Hyp5]enkephalin

P. Clapés, J. Torres, 1997 .

Synthesis and biological activity of O-glycosylated morphiceptin analogues

F. Albericio, M. Sacristán, P. Clapés, 1991 .

Chromatographic behaviour and purification of N1.5-glycosyl enkephalins

I. Haro, P. Clapés, J. Torres, 1988 .

Biocatalytic synthesis, antimicrobial properties and toxicity studies of arginine derivative surfactants

J. Lorenzo, G. L. Garrote, P. Clapés, 2015, Amino Acids.

N-PROTECTION OF AMINO ACID DERIVATIVES CATALYZED BY IMMOBILIZED PENICILLIN G ACYLASE

M. D. Benaiges, G. Caminal, G. Álvaro, 1996 .

Efficient biocatalytic processes for highly valuable terminally phosphorylated C5 to C9 D-ketoses

P. Clapés, C. Guérard-Hélaine, M. Lemaire, 2014 .

Cascade Synthesis of l-Homoserine Catalyzed by Lyophilized Whole Cells Containing Transaminase and Aldolase Activities: The Mathematical Modeling Approach

S. Charnock, M. Sudar, P. Clapés, 2021, Industrial & Engineering Chemistry Research.

Engineering the donor selectivity of D-fructose-6-phosphate aldolase for biocatalytic asymmetric cross-aldol additions of glycolaldehyde.

J. Joglar, Xavier Garrabou, P. Clapés, 2014, Chemistry.

Solid-Phase Synthesis of Glycopeptide Amides under Mild Conditions: Morphiceptin Analogues

F. Albericio, P. Clapés, E. Bardaji, 1990 .

Biocatalytic synthesis, antimicrobial properties and toxicity studies of arginine derivative surfactants

J. Lorenzo, G. L. Garrote, P. Clapés, 2015, Amino Acids.

Enzymatic synthesis of arginine-based cationic surfactants.

M. Infante, P. Clapés, C. Morán, 1999, Biotechnology and bioengineering.

Biocatalytic Construction of Quaternary Centers by Aldol Addition of 3,3-Disubstituted 2-Oxoacid Derivatives to Aldehydes.

J. Joglar, P. Clapés, T. Parella, 2020, Journal of the American Chemical Society.

Amino acid-based surfactants

M. Infante, L. Pérez, M. Morán, 2004 .

Synthesis of glycero amino acid-based surfactants. Part 2. Lipase-catalysed synthesis of 1-O-lauroyl-rac-glycero-3-O-(Nα-acetyl-L-amino acid) and 1,2-di-O-lauroyl-rac-glycero-3-O-(Nα-acetyl-L-amino acid) derivatives

M. Infante, P. Clapés, C. Morán, 2002 .

Determination of the β-glycosylate fraction of contaminants of emerging concern in lettuce (Lactuca sativa L.) grown under controlled conditions

Carlos Hurtado, C. Domínguez, J. Bayona, 2018, Analytical and Bioanalytical Chemistry.

Mathematical model for aldol addition catalyzed by two D-fructose-6-phosphate aldolases variants overexpressed in E. coli.

D. Vasić-Rački, Z. Findrik, M. Sudar, 2013, Journal of biotechnology.

Enzymatic peptide synthesis in low water content systems: preparative enzymatic synthesis of [Leu]- and [Met]-enkephalin derivatives.

P. Adlercreutz, P. Clapés, J. Torres, 1995, Bioorganic & medicinal chemistry.

Enzymatic synthesis of X-Phe-Leu-NH2 in low water content systems: influence of the N-alpha protecting group and the reaction medium composition.

P. Adlercreutz, P. Clapés, J. Torres, 1993, Biochimica et biophysica acta.

New enzymatic approach to the synthesis of convenient aspartic acid intermediates in peptide chemistry. Synthesis of n-benzyloxycarbonyl-l-aspartic acid β-allyl ester.

P. Clapés, N. Xaus, E. Bardaji, 1990 .

Sequential Biocatalytic Aldol Reactions in Multistep Asymmetric Synthesis: Pipecolic Acid, Piperidine and Pyrrolidine (Homo)Iminocyclitol Derivatives from Achiral Building Blocks

Xavier Garrabou, Pere Clapés, Jordi Bujons, 2014 .

Amino Acid-based Surfactants: Enzymatic Synthesis, Properties and Potential Applications

P. Clapés, M. Rosa Infante, 2002 .

Study Cases of Enzymatic Processes

M. T. Moreira, J. Lema, R. Fernández-Lafuente, 2008 .

Biocatalyzed Synthesis and Structural Characterization of Monoglucuronides of Hydroxytyrosol, Tyrosol, Homovanillic Alcohol, and 3‐(4′‐Hydroxyphenyl)propanol

O. Khymenets, M. Covas, R. Torre, 2006 .

Influence of solvent and water activity on kinetically controlled peptide synthesis.

P. Adlercreutz, P. Clapés, G. Valencia, 1991, Enzyme and microbial technology.

Chemoenzymatic synthesis, structural study and biological activity of novel indolizidine and quinolizidine iminocyclitols.

J. Joglar, Xavier Garrabou, P. Clapés, 2012, Organic & biomolecular chemistry.

Iodination of aromatic residues in peptides by reaction with IPy2BF4

P. Clapés, G. Valencia, M. Garcia-Martin, 1996 .

In situ aldehyde generation for aldol addition reactions catalyzed by d-fructose-6-phosphate aldolase

J. Joglar, P. Clapés, Anna Szekrényi, 2012 .

Asymmetric self- and cross-aldol reactions of glycolaldehyde catalyzed by D-fructose-6-phosphate aldolase.

Xavier Garrabou, Pere Clapés, J. Castillo, 2009, Angewandte Chemie.

Enantioselective Reductive Oligomerization of Carbon Dioxide into l-Erythrulose via a Chemoenzymatic Catalysis.

C. Dumon, L. Vendier, P. Clapés, 2021, Journal of the American Chemical Society.

Carbon-carbon bond-forming enzymes for the synthesis of non-natural amino acids.

J. Joglar, P. Clapés, Mariana L. Gutiérrez, 2012, Methods in molecular biology.

Improved Procedures for the Synthesis of N,N-Diallyltyrosine Intermediates

B. G. Torre, P. Clapés, N. Xaus, 1990 .

Lipase-catalysed selective monoacylation of 1,n-diols with vinyl acetate

P. Clapés, F. Camps, Victoria Framis, 2004 .

Chemo-enzymatic synthesis and glycosidase inhibitory properties of DAB and LAB derivatives.

J. Joglar, P. Clapés, P. Cardona, 2013, Organic & biomolecular chemistry.

Casuarine stereoisomers from achiral substrates: chemoenzymatic synthesis and inhibitory properties.

J. Joglar, P. Clapés, T. Parella, 2014, The Journal of organic chemistry.

Intramolecular Benzoin Reaction Catalyzed by Benzaldehyde Lyase from Pseudomonas Fluorescens Biovar I.

J. Joglar, I. Usón, P. Clapés, 2017, Angewandte Chemie.

Current Trends in Asymmetric Synthesis with Aldolases

Xavier Garrabou, P. Clapés, 2011 .

Cytotoxicity and enzymatic activity inhibition in cell lines treated with novel iminosugar derivatives

J. Castillo, J. Joglar, P. Clapés, 2010, Glycoconjugate Journal.

Minimalist Protein Engineering of an Aldolase Provokes Unprecedented Substrate Promiscuity

W. Fessner, Xavier Garrabou, P. Clapés, 2016 .

Aldolase-catalyzed synthesis of conformationally constrained iminocyclitols: preparation of polyhydroxylated benzopyrrolizidines and cyclohexapyrrolizidines.

Francisco J. Sayago, C. Cativiela, J. Joglar, 2014, Organic letters.

Chemoenzymatic Production of Enantiocomplementary 2-Substituted 3-Hydroxycarboxylic Acids from L-α-Amino Acids

J. Joglar, P. Clapés, J. Bujons, 2021, Advanced synthesis & catalysis.

Stereoselective aldol additions catalyzed by dihydroxyacetone phosphate-dependent aldolases in emulsion systems: preparation and structural characterization of linear and cyclic iminopolyols from aminoaldehydes.

C. Solans, J. Joglar, P. Clapés, 2003, Chemistry.

Synthesis of γ-Hydroxy-α-amino Acid Derivatives by Enzymatic Tandem Aldol Addition–Transamination Reactions

J. Joglar, P. Clapés, Carlos J. Moreno, 2021, ACS catalysis.

“Green” amino acid-based surfactants

M. Infante, L. Pérez, M. Morán, 2004 .

Chemical Structure/Property Relationship in Single-Chain Arginine Surfactants

M. Infante, L. Pérez, P. Clapés, 2001 .

Synthesis of glycero amino acid-based surfactants. Part 1. Enzymatic preparation of rac-1-O-(Nα-acetyl-L-aminoacyl)glycerol derivatives

M. Infante, P. Clapés, C. Morán, 2001 .

Chemo-enzymatic synthesis of arginine-based gemini surfactants.

M. Infante, P. Clapés, E. Piera, 2000, Biotechnology and bioengineering.

Assessment of the potential irritation and photoirritation of novel amino acid-based surfactants by in vitro methods as alternative to the animal tests.

M. Infante, M. Vinardell, M. Mitjans, 2004, Toxicology.

Enzymatic synthesis and physicochemical characterization of glycero arginine-based surfactants

M. Infante, L. Pérez, R. Pons, 2004 .

Chemoenzymatic Synthesis and Antimicrobial and Haemolytic Activities of Amphiphilic Bis(phenylacetylarginine) Derivatives

M. Infante, J. Castillo, M. Vinardell, 2006, ChemMedChem.

Low Potential Ocular Irritation of Arginine-Based Gemini Surfactants and Their Mixtures with Nonionic and Zwitterionic Surfactants

M. Infante, L. Pérez, M. Vinardell, 2003, Pharmaceutical Research.

Qualitative and quantitative analysis of new alkyl amide arginine surfactants by high-performance liquid chromatography and capillary electrophoresis.

M. Infante, P. Erra, P. Clapés, 1999, Journal of chromatography. A.

Convergent in situ Generation of Both Transketolase Substrates via Transaminase and Aldolase Reactions for Sequential One‐Pot, Three‐Step Cascade Synthesis of Ketoses

Marion Lorillière, T. Gefflaut, W. Fessner, 2020 .

Enzymatic Carbon−Carbon Bond Formation in Water-in-Oil Highly Concentrated Emulsions (Gel Emulsions)

C. Solans, J. Esquena, P. Clapés, 2003 .

Substrate specificity of α-chymotrypsin-catalyzed esterification in organic media

P. Adlercreutz, P. Clapés, 1991 .

Novel chemoenzymatic strategy for the synthesis of enantiomerically pure secondary alcohols with sterically similar substituents.

P. Clapés, J. Abad, F. Camps, 2003, The Journal of organic chemistry.

Aldolase‐Catalyzed Asymmetric Synthesis of N‐Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes

W. Fessner, J. Joglar, P. Clapés, 2019, Advanced synthesis & catalysis.

D-fructose-6-phosphate aldolase in organic synthesis: cascade chemical-enzymatic preparation of sugar-related polyhydroxylated compounds.

Pere Clapés, J. Castillo, J. Joglar, 2009, Chemistry.

D-Fagomine lowers postprandial blood glucose and modulates bacterial adhesion.

J. Planas, P. Clapés, J. Torres, 2012, The British journal of nutrition.

Dihydroxyacetone phosphate aldolase catalyzed synthesis of structurally diverse polyhydroxylated pyrrolidine derivatives and evaluation of their glycosidase inhibitory properties.

J. Joglar, J. Calveras, P. Clapés, 2009, Chemistry.

Chapter 10 – Enzymatic CC Bond Formation

P. Clapés, 2016 .

Effect of d‐fagomine on excreted enterobacteria and weight gain in rats fed a high‐fat high‐sucrose diet

J. Pérez‐Jiménez, B. Piña, P. Clapés, 2014, Obesity.

Aldol additions of dihydroxyacetone phosphate to N-Cbz-amino aldehydes catalyzed by L-fuculose-1-phosphate aldolase in emulsion systems: inversion of stereoselectivity as a function of the acceptor aldehyde.

J. Joglar, J. Calveras, P. Clapés, 2005, Chemistry.

Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose-6-phosphate Aldolase.

Israel Sánchez-Moreno, W. Fessner, P. Clapés, 2017, Chemistry.

Recent Advances in Enzyme‐Catalyzed Aldol Addition Reactions

P. Clapés, 2016 .

Redesign of the Phosphate Binding Site of L-Rhamnulose- 1-Phosphate Aldolase towards a Dihydroxyacetone Dependent Aldolase

R. Crehuet, J. Joglar, Xavier Garrabou, 2011 .

Influence of N-amino protecting group on aldolase-catalyzed aldol additions of dihydroxyacetone phosphate to amino aldehydes

R. Crehuet, J. Joglar, J. Calveras, 2006 .

Interaction of antimicrobial arginine-based cationic surfactants with liposomes and lipid monolayers.

M. Infante, J. Castillo, I. Haro, 2004, Langmuir : the ACS journal of surfaces and colloids.

Enzyme‐Catalyzed Aldol Additions

J. Joglar, P. Clapés, 2013 .

Syntheses of dipeptide alcohols and dipeptide aldehyde precursors catalyzed by plant cysteine peptidases

P. Clapés, J. M. Padró, C. R. Llerena-Suster, 2013 .

Nucleophile Promiscuity of Natural and Engineered Aldolases

P. Clapés, Anna Szekrényi, K. Hernández, 2018, Chembiochem : a European journal of chemical biology.

Enzymatic peptide synthesis in organic media: a comparative study of water-miscible and water-immiscible solvent systems.

B. Mattiasson, P. Adlercreutz, P. Clapés, 1990, Journal of biotechnology.

Thermostability Engineering of a Class II Pyruvate Aldolase from Escherichia coli by in Vivo Folding Interference

Đ. Vasić-Rački, P. Clapés, A. Hidalgo, 2021, ACS sustainable chemistry & engineering.

Cascade enzymatic synthesis of l-homoserine – mathematical modelling as a tool for process optimisation and design

Martina Sudar, Đurđa Vasić-Rački, Pere Clapés, 2020 .

Combining Aldolases and Transaminases for the Synthesis of 2‑Amino-4-hydroxybutanoic Acid

W. Fessner, P. D. D. María, J. Joglar, 2017 .

Three-Component Stereoselective Enzymatic Synthesis of Amino-Diols and Amino-Polyols

N. Turner, S. Flitsch, P. Clapés, 2022, JACS Au.

Structure-Guided Engineering of D-Fructose-6-Phosphate Aldolase for Improved Acceptor Tolerance in Biocatalytic Aldol Additions

J. Joglar, P. Clapés, T. Parella, 2015 .

A Mutant D-Fructose-6-Phosphate Aldolase (Ala129Ser) with Improved Affinity towards Dihydroxyacetone for the Synthesis of Polyhydroxylated Compounds

G. Sprenger, M. Sancelme, T. Gefflaut, 2010 .

Recent progress in stereoselective synthesis with aldolases.

Wolf-Dieter Fessner, Pere Clapés, G. Sprenger, 2010, Current opinion in chemical biology.

An innovative route for the production of atorvastatin side-chain precursor by DERA-catalysed double aldol addition

S. Charnock, Đ. Vasić-Rački, Z. Blažević, 2020 .

A new concept for production of (3S,4R)-6-[(benzyloxycarbonyl)amino]-5,6-dideoxyhex-2-ulose, a precursor of D-fagomine

Z. Findrik, M. Sudar, Đ. Vasić-Rački, 2015 .

Highly concentrated water-in-oil emulsions as novel reaction media for protease-catalysed kinetically controlled peptide synthesis

C. Solans, P. Clapés, Laia Espelt, 2001 .

Enzymatic synthesis of carboxyglutamic acid containing peptides in organic media

P. Clapés, J. Torres, E. Pera, 1996 .

Enzymatic resolution of Z-γ,γ′-di-tert-butyl-D,L-carboxyglutamic acid methyl ester

P. Clapés, J. Torres, I. Valverde, 1996 .

Recombinant production of serine hydroxymethyl transferase from Streptococcus thermophilus and its preliminary evaluation as a biocatalyst

P. Ferrer, J. Calveras, G. Caminal, 2005, Applied Microbiology and Biotechnology.

Unifying Scheme for the Biosynthesis of Acyl‐Branched Sugars: Extended Substrate Scope of Thiamine‐Dependent Enzymes

Michael Müller, P. Clapés, K. Hernández, 2022, Angewandte Chemie.

Useful Methods in Enzymatic Synthesis of Peptides: A Comparative Study Focussing on Kinetically Controlled Synthesis of Ac-Phe-Ala-NH2 Catalyzed by α-Chymotrypsin

P. Adlercreutz, P. Clapés, P. Björup, 1999 .

Rapid and efficient preparative purification of building blocks suitable for solid-phase synthesis of neoglycopeptides: Synthesis and purification of O-(2,3,4,6-tetra-O-acetyl-β-d- galactopyranosyl/glucopyranosyl)-N α-fluoren-9-yl- methoxycarbonyl-hydroxyproline

P. Clapés, J. Torres, Eugènia Pagans, 1996, Letters in peptide science.

Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes

Israel Sánchez-Moreno, W. Fessner, J. Joglar, 2018, ACS catalysis.

Highly efficient aldol additions of DHA and DHAP to N-Cbz-amino aldehydes catalyzed by L-rhamnulose-1-phosphate and L-fuculose-1-phosphate aldolases in aqueous borate buffer.

J. Joglar, J. Calveras, Xavier Garrabou, 2011, Organic & biomolecular chemistry.

Current Trends in Asymmetric Synthesis with Aldolases.

Xavier Garrabou, P. Clapés, 2012 .

Biocatalytic Synthesis of Homochiral 2-Hydroxy-4-butyrolactone Derivatives by Tandem Aldol Addition and Carbonyl Reduction

J. Joglar, P. Clapés, T. Parella, 2023, ACS catalysis.

Peptide Synthesis in Non-Aqueous Media

J. A. Feliu, G. Caminal, P. Clapés, 2000 .