Lixiang Chen

发表

Peptide-based cancer therapy: opportunity and challenge.

Yanzhang Li, Yuanfang Ma, Dongdong Wu, 2014, Cancer letters.

Distinct roles for TET family proteins in regulating human erythropoiesis.

J. Li, C. Hillyer, N. Mohandas, 2017, Blood.

Isolation and functional characterization of human erythroblasts at distinct stages: implications for understanding of normal and disordered erythropoiesis in vivo.

N. Taylor, N. Mohandas, X. An, 2013, Blood.

Carbon Dots as a Potential Therapeutic Agent for the Treatment of Cancer‐Related Anemia

X. An, P. Jia, Boyang Wang, 2022, Advanced materials.

Vesicular formation regulated by ERK/MAPK pathway mediates human erythroblast enucleation

N. Mohandas, X. An, Lixiang Chen, 2021, Blood advances.

TET2 deficiency leads to stem cell factor-dependent clonal expansion of dysfunctional erythroid progenitors.

C. Hillyer, N. Mohandas, X. An, 2018, Blood.

normal and disordered erythropoiesis in vivo

N. Taylor, N. Mohandas, X. An, 2017 .

Impaired Intestinal Calcium Absorption in Protein 4.1R-deficient Mice Due to Altered Expression of Plasma Membrane Calcium ATPase 1b (PMCA1b)*

G. Debnath, N. Mohandas, X. An, 2013, The Journal of Biological Chemistry.

Lack of Protein 4.1G Causes Altered Expression and Localization of the Cell Adhesion Molecule Nectin-Like 4 in Testis and Can Cause Male Infertility

J. Conboy, G. Debnath, A. Lambert, 2011, Molecular and Cellular Biology.

Comprehensive proteomic analysis reveals dynamic phospho‐profiling in human early erythropoiesis

Hong Liu, Min Li, Pan Wang, 2022, British journal of haematology.

Anti-tumor effects of a novel chimeric peptide on S180 and H22 xenografts bearing nude mice

Dongdong Wu, Yanfeng Gao, Y. Qi, 2010, Peptides.

Protein 4.1G Regulates Cell Adhesion, Spreading, and Migration of Mouse Embryonic Fibroblasts through the β1 Integrin Pathway*

N. Mohandas, X. An, A. Baines, 2015, The Journal of Biological Chemistry.

Spreading and Migration of Mouse Embryo F ibroblasts through β 1 Integrin Pathway

X. An, A. Baines, Y. Qi, 2015 .

Impairment of human terminal erythroid differentiation by histone deacetylase 5 deficiency.

C. Hillyer, X. An, Lixiang Chen, 2021, Blood.

Protein 4.1N is required for the formation of the lateral membrane domain in human bronchial epithelial cells.

N. Mohandas, X. An, Lixiang Chen, 2018, Biochimica et biophysica acta. Biomembranes.

Single-cell Transcriptomic Landscape of Human Blood Cells

Lihong, G. Zheng, Ping Zhu, 2020 .

DNA methylation status of DNAJA4 is essential for human erythropoiesis.

Lixiang Chen, Ting Wang, Huizhi Zhao, 2022, Epigenomics.

Dynamic changes in murine erythropoiesis from birth to adulthood: implications for the study of murine models of anemia.

C. Hillyer, N. Mohandas, X. An, 2020, Blood advances.

Erythroblast island macrophages: recent discovery and future perspectives

X. An, Lixiang Chen, Yaomei Wang, 2019, Blood science.

Identification and transcriptome analysis of erythroblastic island macrophages.

Yaomei Wang, Gang Huang, Wei Li, 2019, Blood.

Analyses of erythropoiesis from embryonic stem cell‐CD34+ and cord blood‐CD34+ cells reveal mechanisms for defective expansion and enucleation of embryomic stem cell‐erythroid cells

X. An, Lixiang Chen, Huan Zhang, 2022, Journal of cellular and molecular medicine.

Knockdown of spliceosome U2AF1 significantly inhibits the development of human erythroid cells

Jing Liu, Lixiang Chen, Shijie Zhang, 2019, Journal of cellular and molecular medicine.

Isolation and transcriptome analyses of human erythroid progenitors: BFU-E and CFU-E.

N. Mohandas, X. An, J. Hale, 2014, Blood.

Protein 4.1B Suppresses Tumor Metastasis by Regulating Epithelial-mesenchymal Transition Progression in Melanoma Cells

Lixiang Chen, Qiao-zhen Kang, Chengbo Wang, 2019, International journal of medical sciences.

Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC

Yayue Zeng, Mao Ye, X. An, 2015, Oncotarget.

Single-cell transcriptomic landscape of human blood cells

G. Zheng, Ping Zhu, T. Cheng, 2020, National science review.

SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS

C. Hillyer, N. Mohandas, X. An, 2018, Journal of Hematology & Oncology.

A novel peptide from alpha5 helix of Asterina pectinifera cyclin B conjugated to HIV-Tat(49-57) with cytotoxic and apoptotic effects against human cancer cells.

Yanfeng Gao, Y. Qi, Lixiang Chen, 2008, Bioorganic & medicinal chemistry letters.

Flow Cytometric Analysis of Erythroblast Enucleation.

X. An, Lixiang Chen, 2018, Methods in molecular biology.

Flow Cytometry (FCM) Analysis and Fluorescence-Activated Cell Sorting (FACS) of Erythroid Cells.

X. An, Lixiang Chen, 2018, Methods in molecular biology.

Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of β1 integrin

J. Conboy, N. Mohandas, X. An, 2011, Journal of Cell Science.

Targeting neurokinin-3 receptor: a novel anti-angiogenesis strategy for cancer treatment

X. An, Yanfeng Gao, Y. Qi, 2017, Oncotarget.

Cytoskeleton protein 4.1R suppresses murine keratinocyte cell hyperproliferation via activating the Akt/ERK pathway in an EGFR-dependent manner.

Jike Lu, Lixiang Chen, Qiao-zhen Kang, 2019, Experimental cell research.

EpoR-tdTomato-Cre mice enable identification of EpoR expression in subsets of tissue macrophages and hematopoietic cells.

X. An, Lixiang Chen, Huan Zhang, 2021, Blood.

Comprehensive Characterization and Global Transcriptome Analysis of Human Fetal Liver Terminal Erythropoiesis

X. An, Lixiang Chen, Xinhua Guo, 2023, bioRxiv.

Stage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation

X. An, Lixiang Chen, Jing Liu, 2023, Haematologica.

4.1B suppresses cancer cell proliferation by binding to EGFR P13 region of intracellular juxtamembrane segment

X. An, Lixiang Chen, Xinhua Guo, 2019, Cell Communication and Signaling.

Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of β1 integrin

J. Conboy, N. Mohandas, X. An, 2011, Journal of Cell Science.

DNMT1 regulates human erythropoiesis by modulating cell cycle and endoplasmic reticulum stress in a stage-specific manner

Lixiang Chen, Xiaoli Qu, Huizhi Zhao, 2024, Cell death and differentiation.