Yan-ling Wu

发表

CecropinXJ, a silkworm antimicrobial peptide, induces cytoskeleton disruption in esophageal carcinoma cells.

Jianhua Yang, L. Xia, Ji Ma, 2014, Acta biochimica et biophysica Sinica.

Therapeutic effects of antimicrobial peptide on malignant ascites in a mouse model

L. Xia, Ji Ma, Yan-ling Wu, 2018, Molecular medicine reports.

Agriophyllum oligosaccharides ameliorate hepatic injury in type 2 diabetic db/db mice targeting INS-R/IRS-2/PI3K/AKT/PPAR-γ/Glut4 signal pathway.

J. Nan, Yan-ling Wu, Shuyin Bao, 2020, Journal of ethnopharmacology.

Anti-apoptotic activity of gentiopicroside in D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2010, Chemico-biological interactions.

Parthenolide, bioactive compound of Chrysanthemum parthenium L., ameliorates fibrogenesis and inflammation in hepatic fibrosis via regulating the crosstalk of TLR4 and STAT3 signaling pathway

J. Nan, Jian Song, Li-Hua Lian, 2021, Phytotherapy research : PTR.

Acanthoic acid, a diterpene in Acanthopanax koreanum, protects acetaminophen-induced hepatic toxicity in mice.

J. Nan, Xuejun Jin, Ying-Zi Jiang, 2010, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Taxifolin blocks monosodium urate crystal-induced gouty inflammation by regulating phagocytosis and autophagy

J. Nan, Li-Hua Lian, Yan-ling Wu, 2022, Inflammopharmacology.

Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways.

Juan Ma, Chunliu Mi, Yue‐Xiao Xing, 2018, Chemico-biological interactions.

Hepatoprotective effects of salidroside on fulminant hepatic failure induced by d‐galactosamine and lipopolysaccharide in mice

J. Nan, Ying-Zi Jiang, Li-Hua Lian, 2009, The Journal of pharmacy and pharmacology.

Modulation of HMGB1 Release in APAP-Induced Liver Injury: A Possible Strategy of Chikusetsusaponin V Targeting NETs Formation

J. Nan, Li-Hua Lian, Yan-ling Wu, 2021, Frontiers in Pharmacology.

Long-term administration of fasudil improves cardiomyopathy in streptozotocin-induced diabetic rats.

J. Weiss, Yan-ling Wu, Zhi-hong Ma, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Design, synthesis, and negative inotropic evaluation of 4‐phenyl‐1H‐1,2,4‐triazol‐5(4H)‐one derivatives containing triazole or piperazine moieties

Yan-ling Wu, H. Piao, Zhi-Yu Wei, 2017, Chemical biology & drug design.

Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α

J. Nan, Li-Hua Lian, Yan-ling Wu, 2012 .

Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2020, Food & function.

Allium victorialis L. Extracts Promote Activity of FXR to Ameliorate Alcoholic Liver Disease: Targeting Liver Lipid Deposition and Inflammation

J. Nan, Li-Hua Lian, Yan-ling Wu, 2021, Frontiers in Pharmacology.

Luteolin attenuates hepatic injury in septic mice by regulating P2X7R-based HMGB1 release.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2021, Food & function.

Betulinic acid and betulin ameliorate acute ethanol-induced fatty liver via TLR4 and STAT3 in vivo and in vitro.

J. Nan, Xuejun Jin, Li-Hua Lian, 2013, International immunopharmacology.

Gentiopicroside Ameliorates the Progression from Hepatic Steatosis to Fibrosis Induced by Chronic Alcohol Intake

J. Nan, Li-Hua Lian, Yan-ling Wu, 2020, Biomolecules & therapeutics.

P2X7R orchestrates the progression of murine hepatic fibrosis by making a feedback loop from macrophage to hepatic stellate cells.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2020, Toxicology letters.

P2X7 receptor‐targeted regulation by tetrahydroxystilbene glucoside in alcoholic hepatosteatosis: A new strategy towards macrophage–hepatocyte crosstalk

J. Nan, Li-Hua Lian, Yan-ling Wu, 2020, British journal of pharmacology.

Liver kinase B1/AMP‐activated protein kinase‐mediated regulation by gentiopicroside ameliorates P2X7 receptor‐dependent alcoholic hepatosteatosis

J. Nan, Xia Li, Li-Hua Lian, 2018, British journal of pharmacology.

Acanthoic acid suppresses lipin1/2 via TLR4 and IRAK4 signalling pathways in EtOH‐ and lipopolysaccharide‐induced hepatic lipogenesis

J. Nan, Jian Song, Li-Hua Lian, 2018, The Journal of pharmacy and pharmacology.

Agriophyllum Oligosaccharides Ameliorate Diabetic Insulin Resistance Through INS-R/IRS/Glut4-Mediated Insulin Pathway in db/db Mice and MIN6 Cells

J. Nan, Yan-ling Wu, L. Bao, 2021, Frontiers in Pharmacology.

Hepatoprotective effect of cryptotanshinone from Salvia miltiorrhiza in D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.

J. Nan, Xuejun Jin, Li-Hua Lian, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Salidroside Regulates Inflammatory Response in Raw 264.7 Macrophages via TLR4/TAK1 and Ameliorates Inflammation in Alcohol Binge Drinking-Induced Liver Injury

J. Nan, Xia Li, Li-Hua Lian, 2016, Molecules.

Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and Metaflammation

J. Nan, Li-Hua Lian, Yan-ling Wu, 2021, Biomolecules & therapeutics.

Modulation of interleukin‐36 based inflammatory feedback loop through the hepatocyte‐derived IL‐36R‐P2X7R axis improves steatosis in alcoholic steatohepatitis

J. Nan, Xia Li, Li-Hua Lian, 2022, British journal of pharmacology.

Baicalein inhibits nuclear factor-κB and apoptosis via c-FLIP and MAPK in D-GalN/LPS induced acute liver failure in murine models.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2010, Chemico-biological interactions.

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages

J. Nan, Li-Hua Lian, Yan-ling Wu, 2020, Inflammopharmacology.

The in vitro and in vivo study of a pyrazole derivative, J-1063, as a novel anti-liver fibrosis agent: Synthesis, biological evaluation, and mechanistic analysis.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2022, Bioorganic chemistry.

Hepatoprotective effects of Sedum sarmentosum on D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure.

J. Nan, Xuejun Jin, Jung Joon Lee, 2010, Journal of pharmacological sciences.

Signaling pathways involved in p38-ERK and inflammatory factors mediated the anti-fibrosis effect of AD-2 on thioacetamide-induced liver injury in mice.

J. Nan, Yan-ling Wu, Yuqing Zhao, 2019, Food & function.

20S-protopanaxatriol ameliorates hepatic fibrosis potentially involving of FXR-mediated inflammatory signaling cascades.

J. Nan, Jian Song, Li-Hua Lian, 2020, Journal of agricultural and food chemistry.

Ginsenoside 25-OCH3-PPD Promotes Activity of LXRs To Ameliorate P2X7R-Mediated NLRP3 Inflammasome in the Development of Hepatic Fibrosis.

J. Nan, Jian Song, Li-Hua Lian, 2018, Journal of agricultural and food chemistry.

Inhibition of P2X7R-NLRP3 Inflammasome Activation by Pleurotus citrinopileatus: A Possible Protective Role in Alcoholic Hepatosteatosis.

J. Nan, Xia Li, Li-Hua Lian, 2018, Journal of agricultural and food chemistry.

Leucodin attenuates inflammatory response in macrophages and lipid accumulation in steatotic hepatocytes via P2x7 receptor pathway: A potential role in alcoholic liver disease.

Y. Li, J. Nan, Xia Li, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Rutin mitigates hepatic fibrogenesis and inflammation through targeting TLR4 and P2X7 receptor signaling pathway in vitro and in vivo

J. Nan, Jian Song, Li-Hua Lian, 2020 .

25-OCH3-PPD induces the apoptosis of activated t-HSC/Cl-6 cells via c-FLIP-mediated NF-κB activation.

J. Nan, Xuejun Jin, Yan-ling Wu, 2011, Chemico-biological interactions.

Acanthoic acid, a diterpene in Acanthopanax koreanum, ameliorates the development of liver fibrosis via LXRs signals.

J. Nan, Xuejun Jin, Li-Hua Lian, 2014, Chemico-biological interactions.

Ginsenoside Rh2 Downregulates LPS-Induced NF-κB Activation through Inhibition of TAK1 Phosphorylation in RAW 264.7 Murine Macrophage

J. Nan, Li-Hua Lian, Yan-ling Wu, 2013, Evidence-based complementary and alternative medicine : eCAM.

Oligomeric proanthocyanidin derived from grape seeds inhibited NF-κB signaling in activated HSC: Involvement of JNK/ERK MAPK and PI3K/Akt pathways.

J. Nan, Xia Li, Li-Hua Lian, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Exogenous pancreatic kininogenase protects against renal fibrosis in rat model of unilateral ureteral obstruction

Jian Jin, Y. Quan, S. Piao, 2020, Acta Pharmacologica Sinica.

Acanthoic acid protectsagainst ethanol-induced liver injury: Possible role of AMPK activation and IRAK4 inhibition.

J. Nan, Jian Song, Li-Hua Lian, 2017, Toxicology letters.

Hepatoprotective effects of salidroside on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.

J. Nan, Ying-Zi Jiang, Li-Hua Lian, 2009, The Journal of pharmacy and pharmacology.

Genus Gentiana: A review on phytochemistry, pharmacology and molecular mechanism.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2020, Journal of ethnopharmacology.

Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway.

J. Nan, Ying-Zi Jiang, Li-Hua Lian, 2010, World journal of gastroenterology.

Thymoquinone Attenuates Acetaminophen Overdose-Induced Acute Liver Injury and Inflammation Via Regulation of JNK and AMPK Signaling Pathway.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2019, The American journal of Chinese medicine.

Amelioration of Alcoholic Liver Steatosis by Dihydroquercetin through the Modulation of AMPK-Dependent Lipogenesis Mediated by P2X7R-NLRP3-Inflammasome Activation.

J. Nan, Xia Li, Li-Hua Lian, 2018, Journal of agricultural and food chemistry.

Gentiana manshurica Kitagawa reverses acute alcohol-induced liver steatosis through blocking sterol regulatory element-binding protein-1 maturation.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2010, Journal of agricultural and food chemistry.

Thymoquinone attenuates liver fibrosis via PI3K and TLR4 signaling pathways in activated hepatic stellate cells.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2013, International immunopharmacology.

CecropinXJ inhibits the proliferation of human gastric cancer BGC823 cells and induces cell death in vitro and in vivo.

L. Xia, Yan-ling Wu, Fu-chun Zhang, 2015, International journal of oncology.

The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2012, Chemico-biological interactions.

Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway.

J. Nan, Xuejun Jin, Li-Hua Lian, 2011, International immunopharmacology.

Thymoquinone alleviates thioacetamide-induced hepatic fibrosis and inflammation by activating LKB1-AMPK signaling pathway in mice.

J. Nan, Jung Joon Lee, Li-Hua Lian, 2014, International immunopharmacology.

Betulinic acid prevention of d‐galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl‐2 and antioxidant mechanisms

J. Nan, Li-Hua Lian, Yan-ling Wu, 2011, The Journal of pharmacy and pharmacology.

Burden of Disease Measured by Disability-Adjusted Life Years and a Disease Forecasting Time Series Model of Scrub Typhus in Laiwu, China

Xiujun Li, Xianjun Wang, Yan-ling Wu, 2015, PLoS neglected tropical diseases.

Salidroside Regulates Inflammatory Response in Raw 264.7 Macrophages via TLR4/TAK1 and Ameliorates Inflammation in Alcohol Binge Drinking-Induced Liver Injury

J. Nan, Xia Li, Li-Hua Lian, 2016, Molecules.

Potentiation of hepatic stellate cell activation by extracellular ATP is dependent on P2X7R‐mediated NLRP3 inflammasome activation

J. Nan, Xia Li, Li-Hua Lian, 2017, Pharmacological research.

Upregulation of SIRT1-AMPK by thymoquinone in hepatic stellate cells ameliorates liver injury.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2016, Toxicology letters.

Thymoquinone, a bioactive component of Nigella sativa Linn seeds or traditional spice, attenuates acute hepatic failure and blocks apoptosis via the MAPK signaling pathway in mice

J. Nan, Li-Hua Lian, Yan-ling Wu, 2015 .

Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2016, Pharmacological research.

Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2016, Toxicology letters.

Tetrandrine regulates hepatic stellate cell activation via TAK1 and NF-κB signaling.

J. Nan, Xia Li, Li-Hua Lian, 2016, International immunopharmacology.

The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice.

J. Nan, Ying-Zi Jiang, Li-Hua Lian, 2010, Journal of ethnopharmacology.

Acanthoic Acid Can Partially Prevent Alcohol Exposure-Induced Liver Lipid Deposition and Inflammation

J. Nan, Li-Hua Lian, Yan-ling Wu, 2017, Front. Pharmacol..

The antibacterial peptide from Bombyx mori cecropinXJ induced growth arrest and apoptosis in human hepatocellular carcinoma cells

Jianhua Yang, L. Xia, Ji Ma, 2016, Oncology letters.

Acanthoic acid, unique potential pimaradiene diterpene isolated from Acanthopanax koreanum Nakai (Araliaceae): A review on its pharmacology, molecular mechanism, and structural modification.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2022, Phytochemistry.

Protective effects of salidroside against acetaminophen-induced toxicity in mice.

J. Nan, Yan-ling Wu, Xue Han, 2008, Biological & pharmaceutical bulletin.

Inhibition of HMGB1/TLR4 Signaling Pathway by Digitoflavone: A Potential Therapeutic Role in Alcohol-Associated Liver Disease.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2022, Journal of agricultural and food chemistry.

[Mechanism of CAG regimen eliminating T-cell acute lymphoblastic leukemia A3 cell line].

Yan-ling Wu, De-Pei Wu, S. Xue, 2008, Zhongguo shi yan xue ye xue za zhi.

Acanthoic acid modulates lipogenesis in nonalcoholic fatty liver disease via FXR/LXRs-dependent manner.

J. Nan, Jian Song, Li-Hua Lian, 2019, Chemico-biological interactions.

Carnosic acid suppressed the formation of NETs in alcoholic hepatosteatosis based on P2X7R-NLRP3 axis.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Resveratrol Regulates Activated Hepatic Stellate Cells by Modulating NF-κB and the PI3K/Akt Signaling Pathway.

J. Nan, Xia Li, Li-Hua Lian, 2016, Journal of food science.

Synthesis of and anti-fibrotic effect of pyrazole derivative J-1048: Inhibition of ALK5 as a novel approach to liver fibrosis targeting inflammation.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2023, Bioorganic chemistry.

Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway.

J. Nan, Xuejun Jin, Li-Hua Lian, 2011, International immunopharmacology.

Protective role of Siberian onions against toxin-induced liver dysfunction: an insight into health-promoting effects.

J. Nan, Li-Hua Lian, Yan-ling Wu, 2022, Food & function.

Thymoquinone alleviates thioacetamide-induced hepatic fibrosis and inflammation by activating LKB1-AMPK signaling pathway in mice.

Jung Joon Lee, Li-Hua Lian, Yan-ling Wu, 2014, International immunopharmacology.

Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway.

Li-Hua Lian, Yan-ling Wu, Yu-qing Zhao, 2016, Toxicology letters.

The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation.

Li-Hua Lian, Yan-ling Wu, Ying Wan, 2012, Chemico-biological interactions.

NETs contribute to psoriasiform skin inflammation: A novel therapeutic approach targeting IL-36 cytokines by a small molecule tetrahydroxystilbene glucoside.

Li-Hua Lian, Yan-ling Wu, Zhihong Zhang, 2024, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Synthesis of amide derivatives containing the imidazole moiety and evaluation of their anti-cardiac fibrosis activity.

Yan-ling Wu, Ji-Xing Nan, Yu-Xuan Yang, 2024, Archiv der Pharmazie.

Combination of cecropinXJ and LY294002 induces synergistic cytotoxicity, and apoptosis in human gastric cancer cells via inhibition of the PI3K/Akt signaling pathway.

L. Xia, Yan-ling Wu, Fu-chun Zhang, 2017, Oncology letters.