John C. Clark

发表

Very high resolution 3D list-mode PET reconstruction using polar voxels

T. Carpenter, T. Fryer, R. Ansorge, 2008, 2008 IEEE Nuclear Science Symposium Conference Record.

Automated synthesis of the generic peptide labelling agent N-succinimidyl 4-[(18)F]fluorobenzoate and application to (18)F-label the vasoactive transmitter urotensin-II as a ligand for positron emission tomography.

J. Pickard, A. Davenport, P. Johnström, 2008, Nuclear medicine and biology.

Measurement of myocardial blood flow with oxygen-15 labelled water: comparison of different administration protocols

Adriaan A. Lammertsma, Stuart D. Rosen, Jaspal S. Kooner, 1998, European Journal of Nuclear Medicine.

Improving the radionuclidic purity of 94mTc for PET imaging

Bradley T. Christian, Robert J. Nickles, T. L. Mulnix, 1995 .

Measurement of Cerebral Blood Flow Using Bolus Inhalation of C15O2 and Positron Emission Tomography: Description of the Method and its Comparison with the C15O2 Continuous Inhalation Method

Iwao Kanno, Adriaan A. Lammertsma, Terry Jones, 1984, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Dosimetry of intravenously administered oxygen-15 labelled water in man: a model based on experimental human data from 21 subjects

Terry Smith, Adriaan A. Lammertsma, Terry Jones, 1994, European Journal of Nuclear Medicine.

Development of a combined microPET®-MR system

Tim D. Fryer, Richard E. Ansorge, T. Adrian Carpenter, 2006 .

Initial performance assessment of a combined microPET® focus-F120 and MR split magnet system

T. Carpenter, T. Fryer, S. Siegel, 2008, 2008 IEEE Nuclear Science Symposium Conference Record.

PET Radionuclide Production

C. Crouzel, V. Pike, G. Stöcklin, 1993 .

An automatic [15O]H2O production system for heart and brain studies

M. Teräs, John C. Clark, H. Sipilä, 2001 .

Responses of Posttraumatic Pericontusional Cerebral Blood Flow and Blood Volume to an Increase in Cerebral Perfusion Pressure

J. Pickard, R. Salvador, D. Menon, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Recommendations for fluorine-18 production

A. Luxen, V. Pike, John C. Clark, 1991 .

Positron emission tomography using 18F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET B receptors in vivo.

J. Pickard, T. Fryer, A. Davenport, 2005, British journal of pharmacology.

Comparison of Lorazepam [7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one] Occupancy of Rat Brain γ-Aminobutyric AcidA Receptors Measured Using in Vivo [3H]Flumazenil (8-Fluoro 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester)

J. Baron, T. Fryer, J. Atack, 2007, Journal of Pharmacology and Experimental Therapeutics.

Imaging post-ischaemic cellular changes using 11C-flumazenil & microPET following temporary distal MCA occlusion in the spontaneous hypertensive rat (SHR)

J. Baron, D. Menon, T. Fryer, 2005 .

Whole Body Vascular Reactivity during the Development of Deoxycorticosterone Acetate Hypertension in the Pig

T. Jones, A. Selwyn, John C. Clark, 2005 .

Continuous Assessment of Regional Myocardial Perfusion in Dogs Using Krypton‐81m

T. Jones, A. Selwyn, John C. Clark, 1978, Circulation research.

Building on a 50‐year legacy of the MRC Cyclotron Unit: the Hammersmith radiochemistry pioneering journey

John C. Clark, S. Luthra, F. Brady, 2007 .

Comparison of Lorazepam [7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2 H -1,4-benzodiazepin-2-one] Occupancy of Rat Brain (cid:1) -Aminobutyric Acid A Receptors Measured Using in Vivo [ 3 H]Flumazenil (8-Fluoro 5,6-dihydro-5-methyl-6-oxo-4 H -imidazo[1,5- a ][1,4]benzodiazepine-3-carboxylic Ac

J. Baron, T. Fryer, J. Atack, 2007 .

Comparison of Lorazepam Occupancy of Rat Brain GABAA Receptors Measured Using In Vivo [H]Flumazenil Binding and [C]Flumazenil microPET

J. Baron, T. Fryer, J. Atack, 2006 .

Imaging Endothelin ETB Receptors Using [18F]-BQ3020: In Vitro Characterization and Positron Emission Tomography (MicroPET)

J. Pickard, T. Fryer, P. Weissberg, 2006, Experimental biology and medicine.

PET imaging of pulmonary fibrosis.

A. Boobis, K. Hamacher, H. Coenen, 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Rapid preparation of [11C]flumazenil: captive solvent synthesis combined with purification by analytical sized columns

J. Baron, F. Aigbirhio, John C. Clark, 2007 .

Short-lived radioactive gases for clinical use

P. Buckingham, John C. Clark, 1975 .

Positron emission tomography using 18F‐labelled endothelin‐1 reveals prevention of binding to cardiac receptors owing to tissue‐specific clearance by ETB receptors in vivo

J. Pickard, T. Fryer, A. Davenport, 2005 .

Positron emission tomography of [18F]‐big endothelin‐1 reveals renal excretion but tissue‐specific conversion to [18F]‐endothelin‐1 in lung and liver

J. Pickard, T. Fryer, A. Davenport, 2010, British journal of pharmacology.

Intersubject Variability and Reproducibility of 15O PET Studies

John D Pickard, David K Menon, Peter Smielewski, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cyclotron production of short-lived radionuclides and labelled compounds for use in biomedical research and clinical diagnosis

John C. Clark, 1994 .

Influence of Acetazolamide on Pulmonary Transfer of Oxygen- and Carbon-Labelled CO2 in Man

P. Buckingham, John C. Clark, H. Jones, 1986 .

Effect of hyperventilation on cerebral blood flow in traumatic head injury: Clinical relevance and monitoring correlates*

Guy B. Williams, T. Carpenter, T. Donovan, 2002, Critical care medicine.

Correlation between Cerebral Blood Flow, Substrate Delivery, and Metabolism in Head Injury: A Combined Microdialysis and Triple Oxygen Positron Emission Tomography Study

John D Pickard, David K Menon, John C Clark, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Positron emission tomographic cerebral perfusion disturbances and transcranial Doppler findings among patients with neurological deterioration after subarachnoid hemorrhage.

Marek Czosnyka, John D Pickard, David K Menon, 2003, Neurosurgery.

Diffusion limited oxygen delivery following head injury*

T. Carpenter, J. Pickard, D. Menon, 2004, Critical care medicine.

Incidence and Mechanisms of Cerebral Ischemia in Early Clinical Head Injury

Guy B. Williams, T. Carpenter, J. Pickard, 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Measurement of brain tissue oxygenation performed using positron emission tomography scanning to validate a novel monitoring method.

J. Pickard, D. Menon, T. Fryer, 2002, Journal of neurosurgery.

Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury*

J. Pickard, D. Menon, T. Fryer, 2005, Critical care medicine.

(18)F-Endothelin-1, a positron emission tomography (PET) radioligand for the endothelin receptor system: radiosynthesis and in vivo imaging using microPET.

J. Pickard, T. Fryer, A. Davenport, 2002, Clinical science.

Redefining the functional organization of working memory processes within human lateral prefrontal cortex

N. J. Herrod, T. Robbins, M. Petrides, 1999, The European journal of neuroscience.

Hyperventilation following head injury: Effect on ischemic burden and cerebral oxidative metabolism*

Guy B. Williams, T. Carpenter, M. Coleman, 2007, Critical care medicine.

Does induced hypertension reduce cerebral ischaemia within the traumatized human brain?

Guy B. Williams, Guy B Williams, John D Pickard, 2004, Brain : a journal of neurology.

Identification of Culprit Lesions After Transient Ischemic Attack by Combined 18F Fluorodeoxyglucose Positron-Emission Tomography and High-Resolution Magnetic Resonance Imaging

Martin J Graves, Jonathan H Gillard, John C Clark, 2005, Stroke.

Defining Ischemic Burden after Traumatic Brain Injury Using 15O PET Imaging of Cerebral Physiology

John D Pickard, David K Menon, Peter Smielewski, 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Assessment of Cerebrovascular Autoregulation in Head-Injured Patients: A Validation Study

Marek Czosnyka, John D Pickard, David K Menon, 2003, Stroke.

Monte Carlo simulation and scatter correction of the GE Advance PET scanner with SimSET and Geant4

Olivier Barret, T Adrian Carpenter, John C Clark, 2005, Physics in medicine and biology.

In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106

F. Turkheimer, R. Krams, P. Evans, 2014, Molecular imaging.

The Hammersmith Philosophy for PET Chemistry Automation

John C. Clark, Keith Dowsett, Colin Steel, 1995 .

Radiochemistry automation for PET

John C. Clark, Christian Lemaire, Sharon Stone-Elander, 1993 .

Chemistry of Nitrogen‐13 and Oxygen‐15

F. Aigbirhio, John C. Clark, 2005 .

Imaging Endothelin ET B Receptors Using ( 18 F)-BQ3020: In Vitro Characterization and

J. Pickard, T. Fryer, P. Weissberg, 2006 .

Positron emission tomography in the quantification of cellular and biochemical responses to intrapulmonary particulates.

A. Boobis, C. Haslett, K. Hamacher, 2005, Toxicology and applied pharmacology.

An External Counting Method for Regional Measurements of Extravascular Lung Water1

F. Fazio, P. Buckingham, C. Rhodes, 1975 .

Positron Emission Tomographic Cerebral Perfusion Disturbances and Transcranial Doppler Findings among Patients with Neurological Deterioration after Subarachnoid Hemorrhage

J. Pickard, D. Menon, M. Czosnyka, 2003 .

Strategy for improved [11C]DAA1106 radiosynthesis and in vivo peripheral benzodiazepine receptor imaging using microPET, evaluation of [11C]DAA1106

E. Warburton, T. Fryer, P. Weissberg, 2007 .

Imaging of Brain Hypoxia in Permanent and Temporary Middle Cerebral Artery Occlusion in the Rat using 18F-Fluoromisonidazole and Positron Emission Tomography: A Pilot Study

Young T. Hong, Jean-Claude Baron, David K Menon, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

HETEROGENEITY OF CEREBROVASCULAR REACTIVITY IN ACUTE BRAIN INJURY MEASURED BY 15O POSITRON EMISSION TOMOGRAPHY

J. Pickard, D. Menon, M. Czosnyka, 1997 .

An automated method for regular productions of copper-64 for PET radiopharmaceuticals

F. Aigbirhio, O. Golovko, John C. Clark, 2010 .

Cerebrovascular pressure reactivity is related to global cerebral oxygen metabolism after head injury

T. Donovan, J. Pickard, D. Menon, 2003, Journal of neurology, neurosurgery, and psychiatry.

In Vivo Imaging of Cardiovascular Endothelin Receptors Using the Novel Radiolabelled Antagonist [18F]-SB209670 and Positron Emission Tomography (microPET)

J. Pickard, T. Fryer, A. Davenport, 2004, Journal of cardiovascular pharmacology.