B. Ponder

A. Whittemore, B. Ponder, B. Werness, 2000, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Pathology of Ovarian Cancers in BRCA1 and BRCA2 Carriers

J. Klijn, D. Easton, B. Weber, 2004, Clinical Cancer Research.

Risk factors for the incidence of breast cancer: do they affect survival from the disease?

D. Easton, P. Pharoah, M. Shah, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Common germ-line polymorphism of C1QA and breast cancer survival

C. Caldas, P. Pharoah, A. Teschendorff, 2010, British Journal of Cancer.

Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population‐based study

N E Day, D. Easton, P. Pharoah, 2001, Genetic epidemiology.

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes

N E Day, N. Day, M. Stratton, 2002, British Journal of Cancer.

Mutation screening of the CDKN2A promoter in melanoma families

D. Bishop, G. Mann, M. Tucker, 2000, Genes, chromosomes & cancer.

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers

B. Ponder, Yusuke Nakamura, T. Tsunoda, 2011, International journal of cancer.

Genetic heterogeneity of early-onset familial breast cancer

S. Mazoyer, S. Narod, H. Sobol, 1992, Human Genetics.

Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker

B. Ponder, Yusuke Nakamura, Y. Atomi, 2011, Cancer science.

Molecular analysis of neurofibromatosis type 1 mutations

M. Wallace, M. Ponder, B. Ponder, 1992, Human mutation.

Loss of neurofibromin in adrenal gland tumors from patients with neurofibromatosis type I

F. Collins, J. Cole, D. Gutmann, 1994, Genes, chromosomes & cancer.

Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer

A. Whittemore, P. Pharoah, I. Jacobs, 2007, Human mutation.

Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers

P. Pharoah, S. Gayther, B. Ponder, 2000, International journal of cancer.

Risk models for familial ovarian and breast cancer

D. Easton, A. Antoniou, S. Gayther, 2000, Genetic epidemiology.

Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate risk variants and target genes of 27 breast cancer risk loci

Ana-Teresa Maia, S. Samarajiwa, B. Ponder, 2022, medRxiv.

Low frequency of germline mutations in the RET proto‐oncogene in patients with apparently sporadic medullary thyroid carcinoma

C Eng, C. Healey, L. Mulligan, 1995, Clinical endocrinology.

BRCA2 arg372hispolymorphism and epithelial ovarian cancer risk

A. Spurdle, D. Easton, P. Pharoah, 2003, International journal of cancer.

Increased frequency of TP53 mutations in BRCA1 and BRCA2 ovarian tumours

P. Pharoah, S. Gayther, L. Bobrow, 1999, Genes, chromosomes & cancer.

Associations among Mammographic Density, Circulating Sex Hormones, and Polymorphisms in Sex Hormone Metabolism Genes in Postmenopausal Women

E. Denton, R. Warren, M. Dowsett, 2006, Cancer Epidemiology Biomarkers & Prevention.

Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: Implications for genetic testing

B. Ponder, D. Easton, P. Pharoah, 2001, Genes, chromosomes & cancer.

Long-term follow up of a “sporadic” unilateral pheochromocytoma revealing multiple endocrine neoplasia MEN2A-2 in an elderly woman

O. Haas, H. Vierhapper, B. Niederle, 2003, Endocrine pathology.

Polymorphisms in DNA repair genes and epithelial ovarian cancer risk

A. Whittemore, D. Easton, A. Dunning, 2005, International journal of cancer.

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.

A. Whittemore, D. Easton, P. Pharoah, 2008, European journal of cancer.

Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities

B. Ponder, A. Dunning, S. Jackson, 2000, International journal of cancer.

Early diagnosis of the multiple endocrine neoplasia type 2 syndrome: consensus statement

B. Ponder, F. Raue, J. Fischer, 1992, European journal of clinical investigation.

Stem-cell organization in mouse small intestine

D. Winton, B. Ponder, B A Ponder, 1990, Proceedings of the Royal Society of London. Series B: Biological Sciences.

No mutation at codon 918 of the RET gene in a family with multiple endocrine neoplasia type 2B

C. Eng, Darrin P. Smith, B. Ponder, 1995, Clinical endocrinology.

De-novo mutations of the RET proto-oncogene in Hirschsprung's disease

A. Munnich, C. Eng, S. Lyonnet, 1994, The Lancet.

Confidential inquiries should be funded in clinical genetics

B. Ponder, H. Harris, B. Modell, 2001, BMJ : British Medical Journal.

Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours.

C. Healey, L. Mulligan, C. Eng, 1994, Human molecular genetics.

Guidelines for diagnosis and therapy of MEN type 1 and type 2.

B. Ponder, J. Bilezikian, M. Brandi, 2001, The Journal of clinical endocrinology and metabolism.

The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.

C Eng, P Komminoth, D. Clayton, 1996, JAMA.

Allele loss from large regions of chromosome 17 is common only in certain histological subtypes of ovarian carcinomas.

B. Ponder, B. Ponder, E. Oláh, 1996, British Journal of Cancer.

High allele loss rates at I7q I2‐q2I in breast and ovarian tumors from BRCAI‐linked families

J. Chang-Claude, B. Ponder, C. Larsson, 1995 .

Degenerate oligonucleotide-primed PCR: general amplification of target DNA by a single degenerate primer.

N. Carter, B. Ponder, H. Telenius, 1992, Genomics.

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.

J Chang-Claude, M. Stratton, J. Chang-Claude, 1998, American journal of human genetics.

RET activation by germline MEN2A and MEN2B mutations.

M. Borrello, C. Eng, M. Pierotti, 1995, Oncogene.

Localization of the gene for Cowden disease to chromosome 10q22–23

E. Mariman, D. Easton, R. Eeles, 1996, Nature Genetics.

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

Wei Lu, Nina Ditsch, Julian Peto, 2013, American journal of human genetics.

Gross deletions of the neurofibromatosis type 1 (NF1) gene are predominantly of maternal origin and commonly associated with a learning disability, dysmorphic features and developmental delay

D. Cooper, M. Krawczak, M. Upadhyaya, 1998, Human Genetics.

Loss of NF1 alleles in phaeochromocytomas from patients with type 1 neurofibromatosis

Barry F. Smith, C. Mathew, L. Mulligan, 1992, Genes, chromosomes & cancer.

Allele losses in the region 17q12–21 in familial breast and ovarian cancer involve the wild–type chromosome

D. Easton, B. Ponder, D. Easton, 1992, Nature Genetics.

Involvement of Brca2 in DNA repair.

B. Ponder, M. Evans, W. Colledge, 1998, Molecular cell.

Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group.

B. Ponder, D. Easton, P. Pharoah, 1999, Cancer research.

A low proportion of BRCA2 mutations in Finnish breast cancer families.

B. Ponder, H. Nevanlinna, H. Eerola, 1997, American journal of human genetics.

The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study.

B. Ponder, D. Easton, M. Gore, 1999, American journal of human genetics.

Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population.

B. Ponder, H. Anton-Culver, G. Casey, 1997, American journal of human genetics.

Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study.

M. King, M. Skolnick, D. Easton, 1996, American journal of human genetics.

DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.

J. Herman, S. Baylin, B. Ponder, 2001, Human molecular genetics.

Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21.

D. Easton, S. Mazoyer, R. Dicioccio, 1994, American journal of human genetics.

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations.

M. Stratton, M. J. van de Vijver, J. Chang-Claude, 1998, Journal of the National Cancer Institute.

The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.

B. Ponder, D. Easton, A. Antoniou, 1999, American journal of human genetics.

Contribution of BRCA1 mutations to ovarian cancer.

D. Easton, B. Ponder, D. Easton, 1997, The New England journal of medicine.

The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2.

M. Stratton, M. J. van de Vijver, J. Chang-Claude, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening.

M. Skolnick, F. Couch, S. Ingles, 1995, JAMA.

Association of a common variant of the CASP8 gene with reduced risk of breast cancer.

B. Ponder, A. Cox, P. Pharoah, 2004, Journal of the National Cancer Institute.

Diverse phenotypes associated with exon 10 mutations of the RET proto-oncogene.

L. Mulligan, C. Eng, D. Marsh, 1994, Human molecular genetics.

Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis. UKCCCR Familial Ovarian Cancer Study Group.

B. Ponder, S. Gayther, S. Gayther, 1996, American journal of human genetics.

Clonal origin of epithelial ovarian carcinoma: analysis by loss of heterozygosity, p53 mutation, and X-chromosome inactivation.

P. Humphrey, R. Bast, B. Ponder, 1992, Journal of the National Cancer Institute.

Administration of gonadotropins stimulates proliferation of normal mouse ovarian surface epithelium.

B. Ponder, B. Davies, S. Smith, 1999, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.

Identification of germ-line E-cadherin mutations in gastric cancer families of European origin.

Kylie L. Gorringe, B. Ponder, C. Caldas, 1998, Cancer research.

Molecular Genetics of Cancer

B. Ponder, B. Ponder, B A Ponder, 1992, Nature Medicine.

Degenerate oligonucleotide primed-polymerase chain reaction-based array comparative genomic hybridization for extensive amplicon profiling of breast cancers : a new approach for the molecular analysis of paraffin-embedded cancer tissue.

Kylie L. Gorringe, S. Chin, C. Caldas, 2001, The American journal of pathology.

An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families. Breast Cancer Linkage Consortium.

A. Whittemore, J. Chang-Claude, B. Ponder, 1995, American journal of human genetics.

Hereditary ovarian cancer: Heterogeneity in age at diagnosis

H. Lynch, P. Watson, B. Ponder, 1991 .

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

M. Thun, M. Stratton, N. Rahman, 2009, Nature Genetics.

A multiple interval physical map of the pericentromeric region of human chromosome 10

G. Finocchiaro, M. Jackson, L. Mulligan, 1994, Human Genetics.

Instability of short tandem repeats (microsatellites) in human cancers

M. Stratton, B. Ponder, R. Wooster, 1994, Nature Genetics.

Diversity of RET proto-oncogene mutations in familial and sporadic Hirschsprung disease.

A. Munnich, L. Mulligan, C. Eng, 1995, Human molecular genetics.

Cowden syndrome and Lhermitte-Duclos disease in a family: a single genetic syndrome with pleiotropy?

S. Seal, B. Ponder, R. Eeles, 1994, Journal of medical genetics.

A Systematic Review Of Genetic Polymorphisms and Breast Cancer Risk 1

B. Ponder, D. Easton, P. Pharoah, 2000 .

Comparison of prophylactic oophorectomy specimens from carriers and noncarriers of a BRCA1 or BRCA2 gene mutation. United Kingdom Coordinating Committee on Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group.

D Lowe, B. Ponder, C. H. Buckley, 1999, Journal of the National Cancer Institute.

A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10

C. Mathew, B. Ponder, D. Easton, 1987, Nature.

Consortium study on 1280 breast carcinomas: allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters.

A. Børresen-Dale, C. Larsson, Å. Borg, 1998, Cancer research.

Thymic lymphomas in mice with a truncating mutation in Brca2.

B. Ponder, K. Abel, M. Evans, 1998, Cancer research.

Mutations of the BRCA1 and BRCA2 genes and the possibilities for predictive testing.

B. Ponder, S. Gayther, S. Gayther, 1997, Molecular medicine today.

Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population.

D. Clayton, D. Easton, M. Stratton, 1997, Human molecular genetics.

Endocrine Neoplasia Type 2 Syndrome Mutations in the Multiple ret The Phenotypes Associated with Updated Version

B. Ponder, B. Ponder, 2007 .

Familial breast cancer.

A. Howell, B. Ponder, D. Evans, 1994, BMJ.

High frequency of germ-line BRCA2 mutations among Hungarian male breast cancer patients without family history.

B. Ponder, N. Udvarhelyi, B. Ponder, 1999, Cancer research.

Genetic linkage analysis in hereditary non-polyposis colon cancer syndrome.

J. Weissenbach, B. Ponder, D. Evans, 1995, Journal of medical genetics.

Expression of multiple endocrine neoplasia 2B RET in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behavior in vivo, and activates Jun kinase.

B. Ponder, J. Hancock, A. Peaston, 1997, Cancer research.

The extent of linkage disequilibrium in four populations with distinct demographic histories.

E Lai, Chun-Fang Xu, B. Ponder, 2000, American journal of human genetics.

Presymptomatic screening for multiple endocrine neoplasia type 2A with linked DNA markers

D. Easton, C. Mathew, B. Ponder, 1991, The Lancet.

Linkage of the multiple endocrine neoplasia type 2B gene (MEN2B) to chromosome 10 markers linked to MEN2A.

R. Norum, H. Willard, B. Ponder, 1990, Genomics.

Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer.

B. Ponder, I. Jacobs, Ian A. Scott, 1996, Cancer research.

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

B. Ponder, M. Evans, F. Thistlethwaite, 1999, Molecular cell.

Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine.

B. Ponder, D. Winton, B. Ponder, 1988, Development.

Multiple endocrine neoplasia type 2.

B. Ponder, B. Ponder, 1990, BMJ.

Multiple endocrine neoplasia

R. Thakker, B. Ponder, 1996 .

Detailed deletion mapping of chromosome segment 17q12-21 in sporadic breast tumours.

B. Ponder, L. Mulligan, S. Mazoyer, 1994, Genes, chromosomes & cancer.

Genetic testing for cancer risk.

B. Ponder, B. Ponder, 1997, Science.

Genetic linkage studies map the multiple endocrine neoplasia type 2 loci to a small interval on chromosome 10q11.2.

R. Norum, D. Easton, L. Mulligan, 1993, Human molecular genetics.

A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10.

B. Ponder, R. Berger, H. Thiesen, 1992, Genomics.

Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk.

B. Ponder, D. Easton, P. Pharoah, 2000, Carcinogenesis.

No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer.

B. Ponder, D. Easton, P. Pharoah, 1999, Carcinogenesis.

Mutation of the RET proto-oncogene is correlated with RET immunostaining in subpopulations of cells in sporadic medullary thyroid carcinoma.

B. Ponder, D. Neuberg, C. Healey, 1998, The Journal of clinical endocrinology and metabolism.

Characterization of RET proto-oncogene 3' splicing variants and polyadenylation sites: a novel C-terminus for RET.

B. Ponder, L. Mulligan, C. Eng, 1995, Oncogene.

A 7 bp deletion of the RET proto-oncogene in familial Hirschsprung's disease.

B. Ponder, A. Munnich, L. Mulligan, 1994, Human molecular genetics.

Overexpression of cyclin D1 in epithelial ovarian cancers.

B. Ponder, B. Davies, B. Ponder, 1997, Gynecologic oncology.

Mapping of Von Hippel-Lindau disease to chromosome 3p confirmed by genetic linkage analysis

D. Barton, M. Ferguson-Smith, M. Ponder, 1990, Journal of the Neurological Sciences.

Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk.

B. Ponder, D. Easton, N. Day, 2001, Carcinogenesis.

Family screening in medullary thyroid carcinoma presenting without a family history.

M. Pembrey, B. Ponder, M. Ponder, 1988, The Quarterly journal of medicine.

A systematic review of genetic polymorphisms and breast cancer risk.

A. Dunning, C. Healey, B. Ponder, 1999, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker

Yusuke Nakamura, Y. Atomi, H. Field, 2011, Cancer science.

Guidelines for diagnosis and therapy of MEN type 1 and type 2.

J. Bilezikian, M. Brandi, R. Thakker, 2001, The Journal of clinical endocrinology and metabolism.

Risk Models for Familial Breast and Ovarian Cancer

D. Easton, A. Antoniou, S. Gayther, 1999 .

Ovarian carcinoma in situ with germline BRCA1 mutation and loss of heterozygosity at BRCA1 and TP53.

A S Whittemore, A. Whittemore, B. Ponder, 2000, Journal of the National Cancer Institute.

The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.

M. Stratton, B. Ponder, R. Eeles, 2000, Cancer research.

Familial breast cancer.

I. Fentiman, K. McPherson, B. Ponder, 1994, BMJ.

Cancer genes and molecular oncology in the clinic

C. Caldas, B. Ponder, B. Ponder, 1997, The Lancet.