P. Darbre

发表

Analysis of aluminium content and iron homeostasis in nipple aspirate fluids from healthy women and breast cancer‐affected patients

F. Mannello, G. Tonti, Virginia Medda, 2011, Journal of applied toxicology : JAT.

Environmental oestrogens, cosmetics and breast cancer.

P. Darbre, 2006, Best practice & research. Clinical endocrinology & metabolism.

Recorded quadrant incidence of female breast cancer in Great Britain suggests a disproportionate increase in the upper outer quadrant of the breast.

P. Darbre, 2005, Anticancer research.

Concentrations of parabens in human breast tumours

G. S. Pope, W. Miller, P. Darbre, 2004, Journal of applied toxicology : JAT.

Underarm cosmetics are a cause of breast cancer

P. Darbre, P. Darbre, 2001, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Long‐term exposure to triclosan increases migration and invasion of human breast epithelial cells in vitro

P. Darbre, A. Farasani, Abdullah Farasani, 2020, Journal of applied toxicology : JAT.

Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks

P. Darbre, P. Harvey, Philippa D. Darbre, 2008, Journal of applied toxicology : JAT.

Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human breast cancer cells

P. Darbre, A. Sadler, D. Pugazhendhi, 2009, The Journal of Steroid Biochemistry and Molecular Biology.

Aluminium and breast cancer: Sources of exposure, tissue measurements and mechanisms of toxicological actions on breast biology.

C. Exley, F. Mannello, P. Darbre, 2013, Journal of inorganic biochemistry.

BODY OF EVIDENCE An overview of the low dose effects of Bisphenol A in relation to breast cancer

P. Darbre, 2013 .

Comparison of the global gene expression profiles produced by methylparaben, n‐butylparaben and 17β‐oestradiol in MCF7 human breast cancer cells

P. Darbre, A. Sadler, D. Pugazhendhi, 2007, Journal of applied toxicology : JAT.

Comparative study of oestrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells

G. S. Pope, P. Darbre, A. Matsumura, 2005, The Journal of Steroid Biochemistry and Molecular Biology.

Differential effects of overexpression of ERα and ERβ in MCF10A immortalised, non-transformed human breast epithelial cells

P. Darbre, D. Pugazhendhi, 2010, Hormone molecular biology and clinical investigation.

Oestrogenic activity of p‐hydroxybenzoic acid (common metabolite of paraben esters) and methylparaben in human breast cancer cell lines

G. S. Pope, P. Darbre, D. Pugazhendhi, 2005, Journal of applied toxicology : JAT.

Effects of estradiol and tamoxifen on human breast cancer cells in serum-free culture.

P. Darbre, R. King, S. Curtis, 1984, Cancer research.

Interaction of phenol red with estrogenic and antiestrogenic action on growth of human breast cancer cells ZR-75-1 and T-47-D.

J. T. Irwin, P. Darbre, J. F. Glover, 1988, Cancer research.

Effects of oestrogen on human breast cancer cells in culture

R. Daly, P. Darbre, 1989 .

Cellular and molecular events in loss of estrogen sensitivity in ZR-75-1 and T-47-D human breast cancer cells.

R. Daly, P. Darbre, 1990, Cancer research.

3,4,3',4'-Tetrachlorobiphenyl acts as an estrogen in vitro and in vivo.

P. Darbre, K. Nesaretnam, R. Dils, 1996, Molecular endocrinology.

3,5,3′,5′-Tetrachlorobiphenyl is a weak oestrogen agonist in vitro and in vivo

P. Darbre, K. Nesaretnam, 1997, The Journal of Steroid Biochemistry and Molecular Biology.

Oestrogenic activity of isobutylparaben in vitro and in vivo

G. S. Pope, P. Darbre, M. Sauer, 2002, Journal of applied toxicology : JAT.

Oestrogenic activity of benzylparaben

G. S. Pope, P. Darbre, N. Coldham, 2003, Journal of applied toxicology : JAT.

Exposure to cyclic volatile methylsiloxanes (cVMS) causes anchorage‐independent growth and reduction of BRCA1 in non‐transformed human breast epithelial cells

P. Darbre, A. Farasani, 2017, Journal of applied toxicology : JAT.

Environmental oestrogens and breast cancer: long-term low-dose effects of mixtures of various chemical combinations

Mariana F. Fernández, P. Darbre, M. Fernández, 2012, Journal of Epidemiology & Community Health.

Aluminium and human breast diseases.

F. Mannello, P. Darbre, D. Pugazhendhi, 2011, Journal of inorganic biochemistry.

Insulin-like Growth Factor Receptor Levels Are Regulated by Cell Density and by Long Term Estrogen Deprivation in MCF7 Human Breast Cancer Cells*

P. Darbre, L. Shaw, D. Corcoran, 2001, The Journal of Biological Chemistry.

Aluminium, antiperspirants and breast cancer.

P. Darbre, Philippa D. Darbre, 2005, Journal of inorganic biochemistry.

Underarm cosmetics and breast cancer

P. Darbre, 2003, Journal of applied toxicology : JAT.

Expression of the androgen-dependent MMTV-specific orf gene in Shionogi 115 mouse mammary tumor cells

P. Härkönen, P. Darbre, E. Valve, 2001, The Journal of Steroid Biochemistry and Molecular Biology.

The history of endocrine-disrupting chemicals

P. Darbre, 2019, Current Opinion in Endocrine and Metabolic Research.

Endocrine disrupters - Preface

P. Darbre, 2006 .

Processing of insulin-like growth factor-II (IGF-II) by human breast cancer cells

Adrian V. Lee, P. Darbre, R. King, 1994, Molecular and Cellular Endocrinology.

An Introduction to the Challenges for Risk Assessment of Endocrine Disrupting Chemicals

P. Darbre, 2015 .

Increased autocrine production of insulin‐like growth factor II (IGF‐II) alters serum sensitivity of MCF‐7 human breast cancer cell proliferation

P. Darbre, D. Corcoran, A. Perachiotti, 1996, Cell proliferation.

Loss of growth inhibitory effects of retinoic acid in human breast cancer cells following long-term exposure to retinoic acid

P. Darbre, R. Stephen, 2000, British Journal of Cancer.

Overexpression of insulin‐like growth factor II (IGFII) in ZR‐75‐1 human breast cancer cells: higher threshold levels of receptor (IGFIR) are required for a proliferative response than for effects on specific gene expression

P. Darbre, P. Darbre, D. Corcoran, 1999, Cell proliferation.

Interaction of growth factors during progression towards steroid independence in T‐47‐D human breast cancer cells

R. Daly, P. Darbre, R. King, 1990, Journal of cellular biochemistry.

Enhanced sensitivity to rapamycin following long-term oestrogen deprivation in MCF-7, T-47-D and ZR-75-1 human breast cancer cells.

M. J. Fry, P. Darbre, Swagat Ray, 2011, The Journal of endocrinology.

Effects of exposure to six chemical ultraviolet filters commonly used in personal care products on motility of MCF‐7 and MDA‐MB‐231 human breast cancer cells in vitro

P. Darbre, M. Alamer, 2018, Journal of applied toxicology : JAT.

Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors

P. Darbre, R. King, 1987, Cell.

What Are Endocrine Disrupters and Where Are They Found

P. Darbre, 2015 .

Transition of human breast cancer cells from an oestrogen responsive to unresponsive state

R. Daly, P. Darbre, 1990, The Journal of Steroid Biochemistry and Molecular Biology.

Approaches to studying the role of growth factors in the progression of breast tumours from the steroid sensitive to insensitive state.

R. Daly, P. Darbre, R. King, 1989, Journal of steroid biochemistry.

Introduction to Practical Molecular Biology

P. Darbre, 1988 .

Concentration of aluminium in breast cyst fluids collected from women affected by gross cystic breast disease

F. Mannello, G. Tonti, P. Darbre, 2009, Journal of applied toxicology : JAT.

Androgen regulation of cell proliferation and expression of viral sequences in mouse mammary tumour cells

G. Peters, C. Dickson, P. Darbre, 1983, Nature.

Haemoglobin Synthesis in Human Erythroid Bursts during Ontogeny: Reproducibility and Sensitivity to Culture Conditions

J. Adamson, D. Weatherall, W. Wood, 1981, British journal of haematology.

Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast

P. Darbre, 2006, Journal of applied toxicology : JAT.

Androgen regulates MMTV RNA in the short-term in S115 mouse mammary tumour cells.

P. Darbre, R. King, S. Curtis, 1985, Journal of steroid biochemistry.

Autocrine production of insulin-like growth factor II using an inducible expression system results in reduced estrogen sensitivity of MCF-7 human breast cancer cells.

R. Daly, P. Darbre, W. Harris, 1991, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Association between insulin-like growth factor receptors & cell density in breast cancer cells.

P. Darbre, C. Larsen, 1996, Biochemical Society transactions.

Effect of estradiol on human breast cancer cells in culture.

P. Darbre, R. King, S. Curtis, 1983, Cancer research.

Hypersensitivity and growth adaptation of oestrogen-deprived MCF-7 human breast cancer cells.

P. Darbre, 2014, Anticancer research.

Changes in oestrogen receptor-α and -β during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells

P. Darbre, A. Sadler, D. Pugazhendhi, 2006, The Journal of Steroid Biochemistry and Molecular Biology.

Cells in Serum-free Culture Effects of Estradiol and Tamoxifen on Human Breast Cancer

P. Darbre, R. King, S. Curtis, 2006 .

Tocotrienols inhibit growth of ZR-75–1 breast cancer cells

P. Darbre, K. Nesaretnam, Selvarajan Dorasamy, 2000, International journal of food sciences and nutrition.

Progression to steroid autonomy is accompanied by altered sensitivity to growth factors in S115 mouse mammary tumour cells

R. Daly, P. Darbre, N. Carrick, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Multihormone regulation of MMTV-LTR in transfected T-47-D human breast cancer cells.

P. Darbre, J. F. Glover, 1989, Journal of steroid biochemistry.

Interaction of different steroid hormones during progression of tumour cells to steroid autonomy

P. Darbre, R. King, 1987, International journal of cancer.

Gamma Chain Variants in Jamaican Newborns

H. Lehmann, P. Darbre, G. Serjeant, 1976 .

Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro

A. Charles, P. Darbre, P. D. Darbre, 2009, Journal of applied toxicology : JAT.

Aluminium in human breast tissue.

C. Exley, A. Polwart, P. Darbre, 2007, Journal of inorganic biochemistry.

The aluminium content of breast tissue taken from women with breast cancer.

C. Exley, A. Polwart, P. Darbre, 2013, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

How Could Endocrine Disrupters Affect Human Health

P. Darbre, 2015 .

Overview of air pollution and endocrine disorders

P. Darbre, 2018, International journal of general medicine.

Endocrine disrupters and human health: could oestrogenic chemicals in body care cosmetics adversely affect breast cancer incidence in women?

P. Darbre, P. Harvey, 2004, Journal of applied toxicology : JAT.

Underarm cosmetics and breast cancer.

P. Darbre, 2004, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Endocrine Disruption and Cancer of Reproductive Tissues

Graeme P. Williams, P. Darbre, 2015 .

Haemoglobin synthesis in CFU‐E‐derived erythroid colonies during sheep ontogeny

P. Darbre, 1982, British journal of haematology.

Patterns of Globin Chain Synthesis in Erythroid Colonies Grown from Sheep Marrow of Different Developmental Stages

J. Adamson, D. Weatherall, P. Darbre, 1979, British journal of haematology.

Method for the complete separation of radioactively labeled human γ-globin chains from pre-βA chains on CM-cellulose chromatography: Use of cold carrier globin chains

P. Darbre, 1980 .

A comparison of the homozygous states for G gamma and G gamma A gamma delta beta thalassaemia.

J. Clegg, D. Weatherall, W. Wood, 1979, British journal of haematology.

The γ chain of the lamb

H. Lehmann, P. Darbre, 1976 .

Hemoglobin Setif (α94 (G1) ASP → TYR) in Iran a Report of 9 Cases

H. Lehmann, P. Darbre, G. Nozari, 1977 .

Endocrine Disruption and Female Reproductive Health

P. Darbre, 2015 .

Molecular mechanisms of oestrogen action on growth of human breast cancer cells in culture

P. Darbre, 2012, Hormone molecular biology and clinical investigation.

Endocrine Disruptors and Obesity

P. Darbre, 2017, Current Obesity Reports.

Chemical components of plastics as endocrine disruptors: Overview and commentary

P. Darbre, 2020, Birth defects research.

Comparison of the myoglobin of the bat-eared fox (Otocyon megalotis) with that of the domestic dog (Canis familiaris).

H. Lehmann, P. Darbre, 1976, Biochimica et biophysica acta.

The myoglobin of the Cape hunting dog (Lycaon pictus).

H. Lehmann, P. Darbre, A. E. Romero-Herrera, 1976, Biochimica et biophysica acta.

Crosstalk with insulin and dependence on PI3K/Akt/mTOR rather than MAPK pathways in upregulation of basal growth following long-term oestrogen deprivation in three human breast cancer cell lines

P. Darbre, Swagat Ray, 2011, Hormone molecular biology and clinical investigation.

Low-dose environmental endocrine disruptors, increase aromatase activity, estradiol biosynthesis and cell proliferation in human breast cells

Graeme P. Williams, P. Darbre, 2019, Molecular and Cellular Endocrinology.

The Actions of Steroid Hormones on Animal Cells in Culture: Mechanisms and Applications

P. Darbre, 1994 .

Oestrogenic activity of parabens in MCF7 human breast cancer cells

G. S. Pope, M. Drew, P. Darbre, 2002, The Journal of Steroid Biochemistry and Molecular Biology.

Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status

P. Darbre, Kalanithi Nesaretnam, Ruth Stephen, 1998, Lipids.

The potential for estrogen disrupting chemicals to contribute to migration, invasion and metastasis of human breast cancer cells

P. Darbre, 2019, Journal of Cancer Metastasis and Treatment.

Exposure to parabens at the concentration of maximal proliferative response increases migratory and invasive activity of human breast cancer cells in vitro

P. Dash, P. Darbre, S. Khanna, 2014, Journal of applied toxicology : JAT.

Exposure to Mixtures of EDCs and Long-Term Effects

P. Darbre, 2022, Endocrine Disruption and Human Health.

Effect of aluminium on migratory and invasive properties of MCF-7 human breast cancer cells in culture.

P. Darbre, A. Bakir, Elzira Iskakova, 2013, Journal of inorganic biochemistry.

Environmental oestrogens and breast cancer: evidence for combined involvement of dietary, household and cosmetic xenoestrogens.

A. Charles, P. Darbre, Amelia K. Charles, 2010, Anticancer research.

Underarm antiperspirants/deodorants and breast cancer

P. Darbre, 2009, Breast Cancer Research.

Parabens can enable hallmarks and characteristics of cancer in human breast epithelial cells: a review of the literature with reference to new exposure data and regulatory status

P. Darbre, P. Harvey, 2014, Journal of applied toxicology : JAT.

Effects of aluminium chloride and aluminium chlorohydrate on DNA repair in MCF10A immortalised non-transformed human breast epithelial cells.

P. Darbre, A. Farasani, 2015, Journal of inorganic biochemistry.

Measurement of paraben concentrations in human breast tissue at serial locations across the breast from axilla to sternum

P. Darbre, L. Barr, L. Savoy, 2012, Journal of applied toxicology : JAT.

Endocrine disrupting chemicals and breast cancer cells.

P. Darbre, 2021, Advances in pharmacology.

DERMAL ABSORPTION OF ALUMINIUM FOLLOWING UNDERARM APPLICATION OF ANTIPERSPIRANT In 2001

P. Darbre, 2020 .

Breast cysts and aluminium-based antiperspirant salts

P. Darbre, 2019 .

Aluminium and the human breast.

P. Darbre, 2016, Morphologie : bulletin de l'Association des anatomistes.

Effect of aluminium on migration of oestrogen unresponsive MDA-MB-231 human breast cancer cells in culture.

P. Darbre, A. Bakir, 2015, Journal of inorganic biochemistry.

6. Steroids and steroid receptors in growth control of cultured breast cancer cells

P. Darbre, 1990 .

Overexpression of insulin-like growth factor II in human breast cancer cells.

P. Darbre, D. Corcoran, A. Perachiotti, 1996, Biochemical Society transactions.

Environmental contaminants in milk: the problem of organochlorine xenobiotics.

P. Darbre, 1998, Biochemical Society transactions.

3,3',4,4'-tetrachlorobiphenyl (TCB) can enhance DMBA-induced mammary carcinogenesis in the rat.

T. Krausz, P. Darbre, Muhammad Sohail, 1998, European journal of cancer.

Endocrine Disruption and Disorders of Energy Metabolism

P. Darbre, 2015 .

Effect of sulphation on the oestrogen agonist activity of the phytoestrogens genistein and daidzein in MCF-7 human breast cancer cells

G. S. Pope, K. Watson, K. Watson, 2008, The Journal of endocrinology.

Effect of Estradici on Human Breast Cancer Cells in Culture

P. Darbre, R. King, S. Curtis, 2006 .

Original Paper 3,3 0 ,4,4 0 -Tetrachlorobiphenyl (TCB) can Enhance DMBA-induced Mammary Carcinogenesis in the Rat

T. Krausz, P. Darbre, E. Hales, 1998 .

Changes in oestrogen receptor-alpha and -beta during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells.

P. Darbre, A. Sadler, D. Pugazhendhi, 2006, The Journal of steroid biochemistry and molecular biology.

Endocrine Disruption and Male Reproductive Health

P. Darbre, 2015 .

Disruption of Other Receptor Systems: Progesterone and Glucocorticoid Receptors, Peroxisome Proliferator-Activated Receptors, Pregnane X Receptor, and Aryl Hydrocarbon Receptor

P. Darbre, 2015 .

Regulatory Considerations for Dermal Application of Endocrine Disrupters in Personal Care Products

P. Darbre, P. Harvey, 2015 .

Endocrine Disrupters in Air

P. Darbre, 2022, Endocrine Disruption and Human Health.

Endocrine Disruption and Human Health

P. Darbre, 2015 .

Environmental oestrogens and breast cancer

P. Darbre, 2008 .

Haemoglobin Stanleyville II (alpha75 [EF 7] Asn yeilds Lys) found in France.

H. Lehmann, P. Darbre, M. North, 1975, Acta haematologica.

Haemoglobin Stanleyville II (α 78 [EF 7] Asn → Lys) Found in France

H. Lehmann, P. Darbre, North Ml, 1975 .

Role of receptor occupancy in the transition from responsive to unresponsive states in cultured breast tumor cells

P. Darbre, R. King, 1988, Journal of cellular biochemistry.

Environmental contaminants: Environmental estrogens - Hazard characterization.

P. Darbre, 2014 .

Disrupters of Estrogen Action and Synthesis

P. Darbre, 2015 .

Parabens enable suspension growth of MCF‐10A immortalized, non‐transformed human breast epithelial cells

P. Darbre, S. Khanna, 2013, Journal of applied toxicology : JAT.

Steroids and steroid receptors in growth control of cultured breast cancer cells.

P. Darbre, 1990, International journal of cancer. Supplement = Journal international du cancer. Supplement.

Oestrogenic and androgenic activity of triclosan in breast cancer cells

A. Charles, P. Darbre, R. Gee, 2008, Journal of applied toxicology : JAT.

Coculture inserts possess an intrinsic ability to alter growth regulation of human breast cancer cells.

P. Darbre, A. Perachiotti, 1994, Experimental cell research.

Haemoglobin G norfolk: α 85 (F6) Asp → Asn

H. Lehmann, F. Vella, P. Darbre, 1975 .

Personal Care Products and Breast Cancer

P. Darbre, 2011 .

Human Health Implications of Personal Care Products: Breast Cancer and Other Breast-Related Diseases

P. Darbre, 2019, Encyclopedia of Environmental Health.

Exposure to cyclic volatile methylsiloxanes (cVMS) causes anchorage‐independent growth and reduction of BRCA1 in non‐transformed human breast epithelial cells

P. Darbre, A. Farasani, 2017, Journal of applied toxicology : JAT.

Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF‐7 human breast cancer cells

P. Darbre, Amelia K. Charles, 2013, Journal of applied toxicology : JAT.

Reply to Robert Golden and Jay Gandy

G. S. Pope, P. Darbre, W. R. Miller, 2004 .