Inhee Choi

发表

Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery.

Joel S. Freundlich, C. Talcott, M. Sarker, 2011, Trends in Microbiology.

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

Se Yeon Kim, R. Wintjens, J. Cechetto, 2013, Nature Medicine.

Classification models for CYP450 3A4 inhibitors and non-inhibitors.

Nam Sook Kang, Kyoung Tai No, Jihoon Jung, 2009, European journal of medicinal chemistry.

Inhibitors of Na+/K+ ATPase exhibit antitumor effects on multicellular tumor spheroids of hepatocellular carcinoma

David Shum, Su-yeon Lee, Inhee Choi, 2020, Scientific Reports.

RETRACTED ARTICLE: Thiophen urea derivatives as a new class of hepatitis C virus entry inhibitors

Tae Kon Kim, H. Yoo, Inhee Choi, 2021, Journal of enzyme inhibition and medicinal chemistry.

Screening of FDA-Approved Drugs Using a MERS-CoV Clinical Isolate from South Korea Identifies Potential Therapeutic Options for COVID-19

M. Bjørås, David Shum, So Young Chang, 2020, bioRxiv.

A combination screening to identify enhancers of para-aminosalicylic acid against Mycobacterium tuberculosis

Inhee Choi, V. Delorme, P. Brodin, 2022, Scientific reports.

Identification of a series of 1,3,4-trisubstituted pyrazoles as novel hepatitis C virus entry inhibitors.

Inhee Choi, Jinhwa Lee, M. Windisch, 2013, Bioorganic & medicinal chemistry letters.

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Susan E. Cellitti, P. Niyomrattanakit, J. Shaffer, 2012, Structure.

Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent.

H. J. Kim, Inhee Choi, Yoonae Ko, 2014, Journal of medicinal chemistry.

Expression of HYOU1 via reciprocal crosstalk between NSCLC cells and HUVECs control cancer progression and chemoresistance in multicellular tumor spheroids

Su-yeon Lee, Inhee Choi, H. Seo, 2020 .

DPP-IV Inhibitory Potentials of Flavonol Glycosides Isolated from the Seeds of Lens culinaris: In Vitro and Molecular Docking Analyses

Inhee Choi, Jin-Baek Kim, C. Jin, 2018, Molecules.

Bayesian Model for the Classification of GPCR Agonists and Antagonists

K. No, Ky-Youb Nam, Inhee Choi, 2010 .

Argininosuccinate synthase 1 suppresses tumor progression through activation of PERK/eIF2α/ATF4/CHOP axis in hepatocellular carcinoma

Su-yeon Lee, Inhee Choi, K. Kim, 2020, Journal of experimental & clinical cancer research : CR.

Chromenopyrimidinone exhibit antitumor effects through inhibition of CAP1 (Adenylyl cyclase-associated protein 1) expression in hepatocellular carcinoma.

J. Y. Lee, Su-yeon Lee, Inhee Choi, 2022, Chemico-biological interactions.

The ThiL enzyme is a valid antibacterial target essential for both thiamine biosynthesis and salvage pathways in Pseudomonas aeruginosa

Soojin Jang, H. J. Kim, Inhee Choi, 2020, The Journal of Biological Chemistry.

ThiL is a valid antibacterial target that is essential for both thiamine biosynthesis and salvage pathway in Pseudomonas aeruginosa

Soojin Jang, H. J. Kim, Inhee Choi, 2020, bioRxiv.

Identification of Piperidine-3-carboxamide Derivatives Inducing Senescence-like Phenotype with Antimelanoma Activities.

Myung Jin Kim, J. Y. Lee, Jiyoung Ryu, 2021, ACS medicinal chemistry letters.

Identification of inhibitors of Bcl-2 family protein-protein interaction by combining the BRET screening platform with virtual screening.

David Shum, Inhee Choi, H. Seo, 2020, Biochemical and biophysical research communications.

Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening

David Shum, C. Radu, R. Durán, 2022, Journal of enzyme inhibition and medicinal chemistry.

A novel 3,4-dihydropyrimidin-2(1H)-one: HIV-1 replication inhibitors with improved metabolic stability.

Doohyun Lee, Sung-Jun Han, Wonyoung So, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors.

J. Cechetto, Inhee Choi, Eunjung Park, 2013, European journal of medicinal chemistry.

Discovery of Phenylaminopyridine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors.

Doohyun Lee, Sung-Jun Han, Wonyoung So, 2012, ACS medicinal chemistry letters.

Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents.

U. Sauer, J. Cechetto, Soojin Jang, 2022, Cell chemical biology.

Chromenopyrimidinone Controls Stemness and Malignancy by suppressing CD133 Expression in Hepatocellular Carcinoma

Inhee Choi, H. Seo, Jason Kim, 2020, Cancers.

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Susan E. Cellitti, P. Niyomrattanakit, J. Shaffer, 2013, Structure.

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Susan E. Cellitti, P. Niyomrattanakit, J. Shaffer, 2012, Structure.

The Medicinal Chemistry of Tuberculosis Chemotherapy

Rachel L. Edwards, L. Via, C. Barry, 2011 .

Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs

David Shum, Soonju Park, Inhee Choi, 2020, Antimicrobial Agents and Chemotherapy.

Oxytetracycline have the therapeutic efficiency in CD133+ HCC population through suppression CD133 expression by decreasing of protein stability of CD133

Inhee Choi, H. Seo, Yeonhwa Song, 2018, Scientific Reports.

Identification of radiation‐induced EndMT inhibitors through cell‐based phenomic screening

Yoon-Jin Lee, David Shum, Inhee Choi, 2018, FEBS open bio.

Discovery of 4H-chromeno[2,3-d]pyrimidin-4-one derivatives as senescence inducers and their senescence-associated antiproliferative activities on cancer cells using advanced phenotypic assay.

Myung Jin Kim, J. Y. Lee, U. Nehrbass, 2020, European journal of medicinal chemistry.

Actinomycin D inhibits the expression of the cystine/glutamate transporter xCT via attenuation of CD133 synthesis in CD133+ HCC.

Inhee Choi, H. Seo, Yeonhwa Song, 2019, Chemico-biological interactions.

Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug

Dae Kim, Inhee Choi, Y. M. Kim, 2022, Journal of enzyme inhibition and medicinal chemistry.

Discovery of benzodioxane analogues as lead candidates of AIMP2-DX2 inhibitors.

Inhee Choi, Sunghoon Kim, BoRa Lee, 2022, Bioorganic & medicinal chemistry letters.

Putative 3D Structure of QcrB from Mycobacterium tuberculosis Cytochrome bc1 Complex, a Novel Drug-Target for New Series of Antituberculosis Agent Q203

Inhee Choi, Yoonae Ko, 2016 .

HO-1089 and HO-1197, Novel Herbal Formulas, Have Antitumor Effects via Suppression of PLK1 (Polo-like Kinase 1) Expression in Hepatocellular Carcinoma

Inhee Choi, H. Seo, Yeonhwa Song, 2023, Cancers.

Target Engagement and Binding Mode of an Antituberculosis Drug to Its Bacterial Target Deciphered in Whole Living Cells by NMR.

M. Nilges, G. Bouvier, N. Izadi-Pruneyre, 2018, Biochemistry.

Expression of HYOU1 via Reciprocal Crosstalk between NSCLC Cells and HUVECs Control Cancer Progression and Chemoresistance in Tumor Spheroids

Inhee Choi, H. Seo, Minji Lee, 2021, Molecules and cells.

QM Scoring Function and its Application to TOP1 Inhibitors

Ky-Youb Nam, Inhee Choi, Kwang-Hwi Cho, 2011 .

Serendipitous discovery of 2-((phenylsulfonyl)methyl)-thieno[3,2-d]pyrimidine derivatives as novel HIV-1 replication inhibitors.

J. Cechetto, Sung-jun Han, Inhee Choi, 2014, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of triazolothienopyrimidine derivatives as novel HIV-1 replication inhibitors.

J. Cechetto, Sung-jun Han, Inhee Choi, 2013, Bioorganic & medicinal chemistry letters.

High‐throughput drug screening using the Ebola virus transcription‐ and replication‐competent virus‐like particle system

David Shum, J. Min, C. Radu, 2018, Antiviral research.

Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH

Inhee Choi, H. Seo, Jason Kim, 2022, Cell Death & Disease.

Structure-activity relationships of antitubercular nitroimidazoles. 3. Exploration of the linker and lipophilic tail of ((s)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-amino PA-824).

P. Niyomrattanakit, Ramandeep Singh, T. Dick, 2011, Journal of medicinal chemistry.

Regioselectivity Prediction of CYP1A2-Mediated Phase I Metabolism

Doo Nam Kim, S. Y. Kim, K. No, 2008, J. Chem. Inf. Model..

Identification of a series of 1,3,4-trisubstituted pyrazoles as novel hepatitis C virus entry inhibitors.

Inhee Choi, Jinhwa Lee, M. Windisch, 2013, Bioorganic & medicinal chemistry letters.

Oxytetracycline have the therapeutic efficiency in CD133+ HCC population through suppression CD133 expression by decreasing of protein stability of CD133

Inhee Choi, H. Seo, Yeonhwa Song, 2018, Scientific Reports.