J. Neres

发表

Towards a new tuberculosis drug: pyridomycin – nature's isoniazid

S. Cole, K. Altmann, S. Magnet, 2012, EMBO molecular medicine.

Selective detection of epimeric pentose saccharides at physiological pH using a fluorescent receptor.

J. Neres, M. Gibson, E. Fullam, 2014, Carbohydrate research.

Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.

S. Cole, Anirban Ghosh, M. Fellows, 2015, Bioorganic & medicinal chemistry.

Tryptophan as a molecular shovel in the glycosyl transfer activity of Trypanosoma cruzi trans-sialidase.

Felicity L. Mitchell, R. Bryce, J. Neres, 2010, Biophysical journal.

Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis

S. Cole, J. Rybniker, C. Sala, 2016, Antimicrobial Agents and Chemotherapy.

Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance

S. Cole, A. Lucarelli, P. Alzari, 2010, Molecular microbiology.

Supplementary Materials for Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

R. Read, S. Cole, A. Lucarelli, 2012 .

Aryl acid adenylating enzymes involved in siderophore biosynthesis: fluorescence polarization assay, ligand specificity, and discovery of non-nucleoside inhibitors via high-throughput screening.

C. Aldrich, J. Neres, Daniel J. Wilson, 2008, Biochemistry.

The Global Virulence Regulators VsrAD and PhcA Control Secondary Metabolism in the Plant Pathogen Ralstonia solanacearum

C. Allen, P. Schneider, D. Hoffmeister, 2009, Chembiochem : a European journal of chemical biology.

DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization.

S. Cole, Jana Korduláková, J. Neres, 2015, ACS chemical biology.

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

T. Buclin, S. Cole, L. Decosterd, 2014, EMBO molecular medicine.

Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening.

Pedro M Alzari, Richard A Bryce, Paul N. Mortenson, 2009, Bioorganic & medicinal chemistry letters.

Mechanism of a Standalone β‐Lactone Synthetase: New Continuous Assay for a Widespread ANL Superfamily Enzyme

L. Wackett, J. Richman, S. Robinson, 2019, Chembiochem : a European journal of chemical biology.

Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: antibacterial nucleosides effective against Mycobacterium tuberculosis.

Courtney C Aldrich, C. Xing, C. Aldrich, 2008, Journal of medicinal chemistry.

Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors.

R. Moreira, J. Neres, J. Iley, 2001, Bioorganic & medicinal chemistry letters.

Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure-activity relationships of the nucleobase domain of 5'-O-[N-(salicyl)sulfamoyl]adenosine.

C. Aldrich, C. Barry, H. Boshoff, 2008, Journal of medicinal chemistry.

Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.

C. Aldrich, C. Barry, H. Boshoff, 2013, Journal of medicinal chemistry.

Rational drug design in parasitology: trans-sialidase as a case study for Chagas disease.

K. Douglas, R. Bryce, J. Neres, 2008, Drug discovery today.

Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase.

P. Alzari, P. Bonnet, K. Douglas, 2007, Bioorganic & medicinal chemistry.

Continuous fluorimetric assay for high-throughput screening of inhibitors of trans-sialidase from Trypanosoma cruzi.

P. Alzari, K. Douglas, A. Buschiazzo, 2006, Analytical biochemistry.

Insights into the Activity and Specificity of Trypanosoma cruzi trans-Sialidase from Molecular Dynamics Simulations

M. Vincent, I. H. Hillier, Felicity L. Mitchell, 2013, Biochemistry.

Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.

L. Tabernero, P. Eyers, M. Chu, 2010, Biochemistry.

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1.

Maria Paola Costi, S. Cole, L. Chiarelli, 2015, ACS chemical biology.

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

J. Mckinney, L. Chiarelli, N. Dhar, 2014, Journal of medicinal chemistry.

The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

S. Cole, V. Makarov, R. Hartkoorn, 2015, Antimicrobial Agents and Chemotherapy.

DprE1--from the discovery to the promising tuberculosis drug target.

V. Makarov, J. Neres, K. Mikušová, 2013, Current pharmaceutical design.

Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity

M. Fellows, J. Neres, V. Ramachandran, 2016, ChemMedChem.

Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis.

C. Aldrich, J. Neres, A. Gulick, 2010, Biochemistry.

Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA.

Karl-Heinz Altmann, S. Cole, K. Altmann, 2014, Nature chemical biology.

Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria.

S. Cole, J. Mckinney, N. Dhar, 2018, ACS chemical biology.

Inhibitors of the Salicylate Synthase (MbtI) from Mycobacterium tuberculosis Discovered by High‐Throughput Screening

C. Aldrich, J. Neres, R. Remmel, 2010, ChemMedChem.

Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA.

S. Cole, K. Altmann, H. Gingell, 2014, Nature chemical biology.