K. Andrews

发表

Design and synthesis of screening libraries based on the muurolane natural product scaffold.

R. Quinn, E. C. Barnes, Vanida Choomuenwai, 2012, Organic & biomolecular chemistry.

Drug repurposing and human parasitic protozoan diseases

K. Andrews, G. Fisher, T. Skinner-Adams, 2014, International journal for parasitology. Drugs and drug resistance.

HIV and malaria co-infection: interactions and consequences of chemotherapy.

J. McCarthy, K. Andrews, D. Gardiner, 2008, Trends in parasitology.

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry

Gregory J. Crowther, W. Hol, W. V. Van Voorhis, 2018, ACS infectious diseases.

Plasmodium gametocyte inhibition identified from a natural-product-based fragment library.

Gregory J. Crowther, W. V. Van Voorhis, R. Quinn, 2013, ACS chemical biology.

Investigation of the in vitro and in vivo efficacy of peptoid-based HDAC inhibitors with dual-stage antiplasmodial activity.

E. Winzeler, F. Hansen, Andrea Schöler, 2020, European journal of medicinal chemistry.

Structure–Activity and Structure–Toxicity Relationships of Peptoid‐Based Histone Deacetylase Inhibitors with Dual‐Stage Antiplasmodial Activity

E. Winzeler, F. Hansen, T. Kurz, 2019, ChemMedChem.

One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.

E. Winzeler, S. Meister, F. Hansen, 2018, European journal of medicinal chemistry.

Histone Deacetylase Inhibitor SB 939 Antimalarial Activity of the Anticancer

G. McFadden, A. Haque, A. Lucke, 2012 .

Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components.

D. Fairlie, A. Lucke, R. Reid, 2010, Bioorganic & medicinal chemistry letters.

Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain

Bill C. H. Chang, Pasi K. Korhonen, P. Sternberg, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

J. Baell, A. Hofmann, R. Gasser, 2017, Parasites & Vectors.

Synthesis and Evaluation of Antimalarial Properties of Novel 4‐Aminoquinoline Hybrid Compounds

K. Andrews, G. Fisher, S. Poulsen, 2014, Chemical biology & drug design.

Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum.

W. Sippl, D. Robaa, F. Erdmann, 2017, European journal of medicinal chemistry.

Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosa.

J. Roberts, K. Andrews, A. Heffernan, 2021, Diagnostic microbiology and infectious disease.

Defining the targets of antiparasitic compounds.

D. Doolan, K. Andrews, Rohan A. Davis, 2016, Drug discovery today.

Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Citation

Alessandro, Serge, Tyler B. Hughes, 2016 .

Plasmodium falciparum: new molecular targets with potential for antimalarial drug development

J. McCarthy, J. Dalton, K. Andrews, 2009, Expert review of anti-infective therapy.

Identification of novel quinazoline derivatives as potent antiplasmodial agents.

A. Mai, P. Arimondo, G. Fabrizi, 2019, European journal of medicinal chemistry.

Antimalarial Asexual Stage-Speciﬁc and Gametocytocidal Activities of HIV Protease Inhibitors (cid:1)

J. McCarthy, T. Macdonald, K. Andrews, 2010 .

Antimalarial Asexual Stage-Specific and Gametocytocidal Activities of HIV Protease Inhibitors

J. McCarthy, T. Macdonald, K. Andrews, 2009, Antimicrobial Agents and Chemotherapy.

Entonalactams A-C: Isoindolinone derivatives from an Australian rainforest fungus belonging to the genus Entonaema.

N. Fechner, P. Healy, Vanida Choomuenwai, 2015, Phytochemistry.

Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp.

A. Carroll, G. Boyle, R. Shivas, 2010, Organic & biomolecular chemistry.

Plasmodium falciparum histone deacetylases

K. Andrews, D. Gardiner, T. Skinner-Adams, 2008 .

The activity of protease inhibitors against Giardia duodenalis and metronidazole-resistant Trichomonas vaginalis.

J. McCarthy, P. Upcroft, K. Andrews, 2007, International journal of antimicrobial agents.

Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line

K. Andrews, M. Duffy, J. Beeson, 2008, Malaria Journal.

Antimalarial activity of natural product extracts from Papua New Guinean and Australian plants against Plasmodium falciparum

V. Avery, K. Andrews, M. Jobling, 2008, Phytotherapy research : PTR.

Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold.

S. Charman, R. Quinn, P. Healy, 2015, Organic & biomolecular chemistry.

Maternal malaria: Plasmodium falciparum sequestration in the placenta

M. Lanzer, K. Andrews, 2002, Parasitology Research.

Antiparasitic activity of alkaloids from plant species of Papua New Guinea and Australia.

V. Avery, K. Andrews, M. Sykes, 2010, International journal of antimicrobial agents.

A novel in vitro image-based assay identifies new drug leads for giardiasis

K. Andrews, J. H. Ryan, T. Skinner-Adams, 2017, International journal for parasitology. Drugs and drug resistance.

Design and Synthesis of Terephthalic Acid‐Based Histone Deacetylase Inhibitors with Dual‐Stage Anti‐Plasmodium Activity

E. Winzeler, S. Meister, F. Hansen, 2017, ChemMedChem.

Structural Basis for Binding of Plasmodium falciparum Erythrocyte Membrane Protein 1 to Chondroitin Sulfate and Placental Tissue and the Influence of Protein Polymorphisms on Binding Specificity*

Joanne M. Chesson, A. M. Lawson, K. Andrews, 2007, Journal of Biological Chemistry.

Antimalarial activity of compounds comprising a primary benzene sulfonamide fragment.

Marie Lopez, K. Andrews, G. Fisher, 2013, Bioorganic & medicinal chemistry letters.

Chemical investigation of an antimalarial Chinese medicinal herb Picrorhiza scrophulariiflora.

R. Quinn, Vanida Choomuenwai, K. Andrews, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and antimalarial evaluation of a screening library based on a tetrahydroanthraquinone natural product scaffold.

Vanida Choomuenwai, K. Andrews, Rohan A. Davis, 2012, Bioorganic & medicinal chemistry.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Manuel Llinás, George Papadatos, Sundari Suresh, 2016, PLoS pathogens.

Synthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives.

K. Andrews, Rohan A. Davis, G. Fisher, 2011, Bioorganic & medicinal chemistry.

Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum.

C. Supuran, D. Vullo, C. Capasso, 2015, Bioorganic & medicinal chemistry.

Catalyst-Controlled Stereoselective Synthesis Secures the Structure of the Antimalarial Isocyanoterpene Pustulosaisonitrile-1.

M. Garson, A. Mándi, T. Kurtán, 2017, The Journal of organic chemistry.

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A–D

J. White, K. Andrews, Rohan A. Davis, 2015, Marine drugs.

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.

E. Winzeler, S. Meister, B. Mordmüller, 2014, European journal of medicinal chemistry.

The discovery, synthesis and antimalarial evaluation of natural product-based polyamine alkaloids

Vanida Choomuenwai, K. Andrews, Rohan A. Davis, 2013 .

A Sesquiterpene Isonitrile with a New Tricyclic Skeleton from the Indo-Pacific Nudibranch Phyllidiella pustulosa: Spectroscopic and Computational Studies

M. Garson, E. Krenske, G. Pierens, 2020 .

Psammaplysin H, a new antimalarial bromotyrosine alkaloid from a marine sponge of the genus Pseudoceratina.

G. Birrell, R. Quinn, K. Andrews, 2011, Bioorganic & medicinal chemistry letters.

Effect of cytokine treatment on the in vitro expression of the P. falciparum adhesion receptor chondroitin-4-sulphate on the surface of human choriocarcinoma (BeWo) cells

J. McCarthy, K. Andrews, R. Schwartz-Albiez, 2007, Parasitology Research.

Carrageenans inhibit the in vitro growth of Plasmodium falciparum and cytoadhesion to CD36

K. Andrews, R. Schwartz-Albiez, Y. Adams, 2005, Parasitology Research.

Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria

Martin J. Stoermer, D. M. Wyatt, J. McCarthy, 2006, Antimicrobial Agents and Chemotherapy.

Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases.

C. Supuran, D. Vullo, C. Capasso, 2014, Bioorganic & medicinal chemistry letters.

Fervidobacterium gondwanense sp. nov., a new thermophilic anaerobic bacterium isolated from nonvolcanically heated geothermal waters of the Great Artesian Basin of Australia.

B. Patel, K. Andrews, 1996, International journal of systematic bacteriology.

Reevaluating the classification of Halobacteroides and Haloanaerobacter species based on sequence comparisons of the 16S ribosomal RNA gene.

B. Patel, J. García, B. Ollivier, 1995, FEMS microbiology letters.

Association of Plasmodium falciparum isolates encoding the p. Falciparum chloroquine resistance transporter gene K76T polymorphism with anemia and splenomegaly, but not with multiple infections.

B. Coulibaly, B. Kouyaté, M. Lanzer, 2005, The American journal of tropical medicine and hygiene.

Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone

Oliver E. Hutt, E. Winzeler, S. Meister, 2019, Communications Biology.

Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone

Oliver E. Hutt, E. Winzeler, S. Meister, 2019, Communications Biology.

Antimalarial Isocyano and Isothiocyanato Sesquiterpenes with Tri- and Bicyclic Skeletons from the Nudibranch Phyllidia ocellata.

M. Garson, E. Krenske, G. Pierens, 2015, Journal of natural products.

Psammaplysin derivatives from the Balinese marine sponge Aplysinella strongylata.

M. Garson, T. A. Hadi, I. W. Mudianta, 2012, Journal of natural products.

Effect of Sequence Variation in Plasmodium falciparum Histidine- Rich Protein 2 on Binding of Specific Monoclonal Antibodies: Implications for Rapid Diagnostic Tests for Malaria

J. Baker, M. Gatton, J. McCarthy, 2006, Journal of Clinical Microbiology.

Antiretrovirals as antimalarial agents.

J. McCarthy, K. Andrews, D. Gardiner, 2004, The Journal of infectious diseases.

RAP1 controls rhoptry targeting of RAP2 in the malaria parasite Plasmodium falciparum

D. Roos, A. Cowman, R. Waller, 2000, The EMBO journal.

Inhibition of Chondroitin-4-Sulfate-Specific Adhesion of Plasmodium falciparum-Infected Erythrocytes by Sulfated Polysaccharides

K. Andrews, R. Schwartz-Albiez, P. Mischnick, 2005, Infection and Immunity.

Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection‡

J. McCarthy, R. Kumar, F. Souza-Fonseca-Guimaraes, 2018, Clinical & translational immunology.

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp.

David M. Shackleford, V. Avery, S. Charman, 2012, Journal of medicinal chemistry.

HDAC inhibitors in parasitic diseases

A. Haque, Malcolm K. Jones, K. Andrews, 2012, Immunology and cell biology.

Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors

Zbynek Bozdech, D. Fairlie, K. Andrews, 2012, PloS one.

Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues

D. Fairlie, G. Boyle, A. Lucke, 2008, Antimicrobial Agents and Chemotherapy.

Targeting histone deacetylase inhibitors for anti-malarial therapy.

D. Fairlie, K. Andrews, David P Fairlie, 2009, Current topics in medicinal chemistry.

Antimalarial Activity of Phenylthiazolyl-Bearing Hydroxamate-Based Histone Deacetylase Inhibitors

L. Gerena, D. Caridha, A. Kozikowski, 2008, Antimicrobial Agents and Chemotherapy.

Antiplasmodial activity of the natural product compounds alstonine and himbeline

R. Quinn, K. Andrews, G. Fisher, 2021, International journal for parasitology. Drugs and drug resistance.

Investigating the antiplasmodial activity of primary sulfonamide compounds identified in open source malaria data

C. Supuran, C. Capasso, K. Andrews, 2017, International journal for parasitology. Drugs and drug resistance.

Adherence of Plasmodium falciparum infected erythrocytes to CHO-745 cells and inhibition of binding by protein A in the presence of human serum.

M. Lanzer, K. Andrews, R. Schwartz-Albiez, 2005, International journal for parasitology.

Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

D. Fairlie, Weijun Xu, R. Pierce, 2016, International journal for parasitology. Drugs and drug resistance.

Discovery of 1,3,4-oxadiazoles with slow-action activity against Plasmodium falciparum malaria parasites

Oliver E. Hutt, A. Davey, K. Andrews, 2023, bioRxiv.

Proteomic analysis of Plasmodium falciparum histone deacetylase 1 complex proteins.

P. Gilson, Jessica A. Engel, G. Blatch, 2019, Experimental parasitology.

Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea‐Based HDAC Inhibitors

F. Hansen, K. Kuna, T. Kurz, 2014, ChemMedChem.

Total synthesis of thiaplakortone a: derivatives as metabolically stable leads for the treatment of malaria.

S. Charman, R. Quinn, K. Andrews, 2014, ACS medicinal chemistry letters.

Antimalarial Activity of the Anticancer Histone Deacetylase Inhibitor SB939

G. McFadden, A. Haque, D. Fairlie, 2012, Antimicrobial Agents and Chemotherapy.

Antimalarial activity of azadipeptide nitriles.

J. Gut, P. Rosenthal, M. Gütschow, 2010, Bioorganic & medicinal chemistry letters.

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by Gram-negative bacilli: A systematic review.

J. Roberts, K. Andrews, A. Heffernan, 2019, International journal of antimicrobial agents.

QSAR Classification Models for Prediction of Hydroxamate Histone Deacetylase Inhibitor Activity against Malaria Parasites.

D. Fairlie, T. Kurz, A. Gorse, 2022, ACS infectious diseases.

Direct Activation of Human Endothelial Cells by Plasmodium falciparum-Infected Erythrocytes

R. Förster, P. Knolle, M. Lanzer, 2005, Infection and Immunity.

Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites

Jessica A. Engel, D. Fairlie, Susanna S. Ng, 2015, International journal for parasitology. Drugs and drug resistance.

Pharmacodynamic Evaluation of Plasma and Epithelial Lining Fluid Exposures of Amikacin against Pseudomonas aeruginosa in a Dynamic In Vitro Hollow-Fiber Infection Model

M. Neely, K. Cottrell, J. Roberts, 2020, Antimicrobial Agents and Chemotherapy.

Ex Vivo Activity of Histone Deacetylase Inhibitors against Multidrug-Resistant Clinical Isolates of Plasmodium falciparum and P. vivax

R. Price, E. Kenangalem, E. Tjitra, 2010, Antimicrobial Agents and Chemotherapy.

Stronger Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors against Clinical Isolates of Plasmodium vivax than against Those of P. falciparum

R. Price, J. McCarthy, F. Nosten, 2008, Antimicrobial Agents and Chemotherapy.

L-alanine production from glucose fermentation by hyperthermophilic members of the domains bacteria and Archaea: a remnant of an ancestral metabolism?

B. Patel, B. Ollivier, M. Magot, 1996, Applied and environmental microbiology.

Design and Synthesis of Novel Anti‐Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit

Jessica A. Engel, B. Mordmüller, F. Hansen, 2017, Archiv der Pharmazie.

The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

E. Winzeler, K. Saliba, M. McConville, 2020, mBio.

Impact of the Epithelial Lining Fluid Milieu on Amikacin Pharmacodynamics Against Pseudomonas aeruginosa

J. Roberts, K. Andrews, A. Heffernan, 2021, Drugs in R&D.

Adaptation of the [3H]Hypoxanthine Uptake Assay for In Vitro-Cultured Plasmodium knowlesi Malaria Parasites

K. Andrews, G. Fisher, T. Skinner-Adams, 2016, Antimicrobial Agents and Chemotherapy.

Evidence for trafficking of PfEMP1 to the surface of P. falciparum-infected erythrocytes via a complex membrane network.

Georg Krohne, Michael Lanzer, G. Krohne, 2003, European journal of cell biology.

An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

T. Kurz, K. Andrews, G. Fisher, 2020, International journal for parasitology. Drugs and drug resistance.

HIV-Malaria Interactions: Don't Forget the Drugs

M. Gatton, J. McCarthy, K. Andrews, 2007, Science.

Synergistic Interactions of the Antiretroviral Protease Inhibitors Saquinavir and Ritonavir with Chloroquine and Mefloquine against Plasmodium falciparum In Vitro

J. McCarthy, K. Andrews, D. Gardiner, 2006, Antimicrobial Agents and Chemotherapy.

Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules

G. McFadden, D. Fairlie, F. Hansen, 2014, Antimicrobial Agents and Chemotherapy.

MoleculesIs a Target for Antimalarial Small Lysine Acetylation in Sexual Stage Malaria

G. McFadden, D. Fairlie, F. Hansen, 2014 .

Inhibition of Plasmodium falciparum Growth In Vitro and Adhesion to Chondroitin-4-Sulfate by the Heparan Sulfate Mimetic PI-88 and Other Sulfated Oligosaccharides

C. Parish, K. Andrews, V. Ferro, 2006, Antimicrobial Agents and Chemotherapy.

Thymidine kinase-independent click chemistry DNADetect™ probes for DNA proliferation assessment in malaria parasites

K. Andrews, G. Fisher, S. Poulsen, 2023, bioRxiv.

Regioselectively modified sulfated cellulose as prospective drug for treatment of malaria tropica

K. Andrews, C. Lieth, M. Kirschfink, 2006, Glycoconjugate Journal.

Towards histone deacetylase inhibitors as new antimalarial drugs.

D. Fairlie, K. Andrews, T. Tran, 2012, Current pharmaceutical design.

Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

W. Sippl, D. Robaa, K. Andrews, 2018, International journal for parasitology. Drugs and drug resistance.

FgoI, a Type II restriction endonuclease from the thermoanaerobe Fervidobacterium gondwanense AB39(T).

B. Patel, K. Andrews, F. Clarke, 1998, Anaerobe.

Evaluation of the role of the endocytic receptor L-SIGN for cytoadhesion of Plasmodium falciparum-infected erythrocytes

Y. Kooyk, P. Knolle, M. Lanzer, 2005, Parasitology Research.

Recovery of adhesion to chondroitin‐4‐sulphate in Plasmodium falciparum var CSA disruption mutants by antigenically similar PfEMP1 variants

Y. Sterkers, A. Scherf, M. Lanzer, 2003, Molecular microbiology.

A human schwannoma cell line supports the in vitro adhesion of Plasmodium falciparum infected erythrocytes to chondroitin-4-sulfate

P. Knolle, M. Lanzer, K. Andrews, 2003, Parasitology Research.

The histone H4 gene of Plasmodium falciparum is developmentally transcribed in asexual parasites

M. Lanzer, K. Andrews, J. Przyborski, 2003, Parasitology Research.