B. Witthuhn

发表

Dystrophinopathy-associated dysfunction of Krebs cycle metabolism

J. Ervasti, A. Lindsay, Christopher M. Chamberlain, 2018, Human molecular genetics.

Attracting Common Carp to a bait site with food reveals strong positive relationships between fish density, feeding activity, environmental DNA, and sex pheromone release that could be used in invasive fish management

P. Sorensen, B. Witthuhn, R. Ghosal, 2018, Ecology and evolution.

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction.

C. Schindler, O. Silvennoinen, G. Barbieri, 1993, Nature.

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

E. Liu, O. Silvennoinen, J. Ihle, 1994, Nature.

A Kinase-deficient Splice Variant of the Human JAK3 Is Expressed in Hematopoietic and Epithelial Cancer Cells (*)

J. Ihle, B. Witthuhn, D. Graham, 1995, The Journal of Biological Chemistry.

The Identification of JAK2 Tyrosine Kinase as a Signaling Molecule for Growth Hormone

J. Ihle, C. Carter-Su, B. Witthuhn, 1994, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

2 Cytokine receptors and signal transduction

J. Ihle, F. Quelle, B. Witthuhn, 1994 .

Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor.

J. Ihle, N. Aoki, Y. Miura, 1994, Blood.

Interleukin 4 signals through two related pathways.

W. Paul, J. Ihle, J. Pierce, 1995, Proceedings of the National Academy of Sciences of the United States of America.

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

N. Sato, J. Ihle, J. Griffin, 1994, Molecular and cellular biology.

Erythropoietin induces association of the JAK2 protein tyrosine kinase with the erythropoietin receptor in vivo.

J. Ihle, N. Aoki, F. Quelle, 1994, Blood.

Lack of constitutive activation of Janus kinases and signal transduction and activation of transcription factors in Philadelphia chromosome-positive acute lymphoblastic leukemia [letter]

D. Campana, J. Ihle, B. Witthuhn, 1996 .

Cytokine receptors and signal transduction.

J. Ihle, F. Quelle, B. Witthuhn, 1994, Bailliere's clinical haematology.

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

O. Silvennoinen, J. Ihle, K. Yasukawa, 1994, Proceedings of the National Academy of Sciences of the United States of America.

In vivo assessment and potential diagnosis of xenobiotics that perturb the thyroid pathway: Proteomic analysis of Xenopus laevis brain tissue following exposure to model T4 inhibitors.

P. Kosian, S. Degitz, J. Korte, 2010, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID.

J. Johnston, O. Silvennoinen, M. Noguchi, 1994, Science.

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits.

O. Silvennoinen, Y. Minami, B. Witthuhn, 1994, Science.

Identification and Origin of N-Linked β-d-N-Acetylglucosamine Monosaccharide Modifications on Arabidopsis Proteins1[W][OA]

J. Shabanowitz, D. Hunt, Young-Cheon Kim, 2012, Plant Physiology.

Proteasome activity in a naïve mosquito cell line infected with Wolbachia pipientis wAlbB

B. Witthuhn, A. Fallon, 2009, In Vitro Cellular & Developmental Biology - Animal.

Requirement for Jak3 in mature T cells: its role in regulation of T cell homeostasis.

R. Perlmutter, J. Ihle, K. Forbush, 1998, Journal of immunology.

Isolation and characterization of the rat beta-subunit gene of the high affinity receptor for immunoglobulin E.

B. Witthuhn, C. Faust, 1996, Molecular immunology.

The Essentiality of Staphylococcal Gcp Is Independent of Its Repression of Branched-Chain Amino Acids Biosynthesis

Junshu Yang, Yinduo Ji, B. Witthuhn, 2012, PloS one.

Functional signatures of ex-vivo dental caries onset

J. Perdigão, T. Mansour, C. Aparicio, 2022, Journal of oral microbiology.

Tissue-specific expression in mouse P815 mastocytoma cells of the cloned rat alpha-subunit gene of the high-affinity receptor for immunoglobulin E.

B. Witthuhn, C. Faust, 1995, Immunology letters.

Interleukin-9 Induces Tyrosine Phosphorylation of Insulin Receptor Substrate-1 via JAK Tyrosine Kinases (*)

G. Lienhard, J. Ihle, M. Tsang, 1995, The Journal of Biological Chemistry.

Mosaic composition of ribA and wspB genes flanking the virB8-D4 operon in the Wolbachia supergroup B-strain, wStr

A. Baldridge, B. Witthuhn, L. Higgins, 2015, Archives of Microbiology.

kinase with the erythropoietin receptor in vivo Erythropoietin induces association of the JAK2 protein tyrosine

N. Aoki, F. Quelle, B. Witthuhn, 2011 .

Mouse Prostate Proteomes Are Differentially Altered by Supranutritional Intake of Four Selenium Compounds

J. Lü, Lei Wang, Guang-xun Li, 2011, Nutrition and cancer.

The insect repellent DEET (N,N-diethyl-3-methylbenzamide) increases the synthesis of glutathione S-transferase in cultured mosquito cells

B. Witthuhn, A. Fallon, Vanessa J. Hellestad, 2011, Cell Biology and Toxicology.

Proteomic analysis of a mosquito host cell response to persistent Wolbachia infection.

A. Baldridge, B. Witthuhn, L. Higgins, 2017, Research in microbiology.

Wolbachia from the planthopper Laodelphax striatellus establishes a robust, persistent, streptomycin-resistant infection in clonal mosquito cells

B. Witthuhn, L. Higgins, A. Fallon, 2012, In Vitro Cellular & Developmental Biology - Animal.

Proteomic profiling of a robust Wolbachia infection in an Aedes albopictus mosquito cell line

A. Baldridge, B. Witthuhn, L. Higgins, 2014, Molecular microbiology.

Wolbachia from the planthopper Laodelphax striatellus establishes a robust, persistent, streptomycin-resistant infection in clonal mosquito cells

B. Witthuhn, A. Fallon, G. Baldridge, 2012, In Vitro Cellular & Developmental Biology - Animal.

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

O. Silvennoinen, J. Ihle, F. Quelle, 1993, Cell.

Dentin Priming with Amphipathic Antimicrobial Peptides

C. Aparicio, B. Witthuhn, Z. Ye, 2019, Journal of dental research.

Defective Lymphoid Development in Mice Lacking Jak3

P. Doherty, J. Ihle, G. Grosveld, 1995, Science.

Identification of candidate biomarkers in ovarian cancer serum by depletion of highly abundant proteins and differential in‐gel electrophoresis

A. Skubitz, B. Witthuhn, Todd W. Markowski, 2010, Electrophoresis.

Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1.

L. Chow, D. Bernlohr, D. Mashek, 2019, Molecular cell.

Signaling through the hematopoietic cytokine receptors.

O. Silvennoinen, J. Ihle, F. Quelle, 1995, Annual review of immunology.

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses

S. Pestka, G. Stark, I. Kerr, 1997, Molecular and cellular biology.

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

J. Cleveland, O. Silvennoinen, J. Ihle, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

O. Silvennoinen, J. Ihle, C. Carter-Su, 1993, Cell.

Signaling by the cytokine receptor superfamily: JAKs and STATs.

O. Silvennoinen, J. Ihle, F. Quelle, 1994, Trends in biochemical sciences.

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.

G. Yancopoulos, O. Silvennoinen, J. Ihle, 1994, Science.

The Action of Interleukin-2 Receptor Subunits Defines a New Type of Signaling Mechanism for Hematopoietin Receptors in Hepatic Cells and Fibroblasts (*)

S. Ziegler, J. Ihle, D. Tweardy, 1995, The Journal of Biological Chemistry.

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway

G. Stark, C. Schindler, O. Silvennoinen, 1993, Nature.

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

I. Kerr, T. Matsuda, J. Ihle, 1997, Molecular and cellular biology.

Activation of JAK kinases and STAT proteins by interleukin‐2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.

I. Kerr, D. Cantrell, C. Beadling, 1994, The EMBO journal.

The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

G. Stark, C. Schindler, O. Silvennoinen, 1993, Nature.

Kinases appartenant a la famille jak et regulation de la transduction du signal de la cytokine

O. Silvennoinen, J. Ihle, F. Quelle, 1994 .

Determination of the transphosphorylation sites of Jak2 kinase.

Y. Sekine, T. Matsuda, J. Ihle, 2004, Biochemical and biophysical research communications.

Kinase‐negative mutants of JAK1 can sustain interferon‐gamma‐inducible gene expression but not an antiviral state.

G. Stark, I. Kerr, J. Ihle, 1996, The EMBO journal.

Differential substrate recognition capabilities of Janus family protein tyrosine kinases within the interleukin 2 receptor (IL2R) system: Jak3 as a potential molecular target for treatment of leukemias with a hyperactive Jak-Stat signaling machinery.

F. Uckun, B. Witthuhn, M. Williams, 1999, Leukemia & lymphoma.

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin‐6.

G. Stark, P. Heinrich, J. Briscoe, 1995, The EMBO journal.

Quantifying Intranasally Administered Deferoxamine in Rat Brain Tissue with Mass Spectrometry.

B. Witthuhn, J. Fine, L. Hanson, 2019, ACS Chemical Neuroscience.

Upregulation of bone morphogenetic protein GDF-3/Vgr-2 expression in adipose tissue of FABP4/aP2 null mice.

D. Bernlohr, B. Witthuhn, 2001, Cytokine.

Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients

A. Skubitz, R. Jemmerson, R. Vogel, 2010, Journal of ovarian research.

Functional Biomarkers of Ex-vivo Dental Caries Onset

J. Perdigão, T. Mansour, C. Aparicio, 2022, bioRxiv.

Proteomic Profiling of Potential Molecular Targets of Methyl-Selenium Compounds in the Transgenic Adenocarcinoma of Mouse Prostate Model

J. Lü, Lei Wang, B. Witthuhn, 2010, Cancer Prevention Research.

Protein tyrosine phosphorylation in the regulation of hematopoiesis by receptors of the cytokine-receptor superfamily.

O. Silvennoinen, J. Ihle, F. Quelle, 1994, Blood cells.

Proteomic comparison of needles from blister rust-resistant and susceptible Pinus strobus seedlings reveals upregulation of putative disease resistance proteins.

J. Smith, R. Blanchette, T. A. Burnes, 2006, Molecular plant-microbe interactions : MPMI.

Tryptophan catabolism in acute exacerbations of chronic obstructive pulmonary disease

T. Griffin, C. Broeckling, C. Reilly, 2016, International journal of chronic obstructive pulmonary disease.

Plasma sphingolipids in HIV-associated chronic obstructive pulmonary disease

T. Griffin, C. Reilly, C. Wendt, 2017, BMJ Open Respiratory Research.

Iron-sparing Response of Mycobacterium avium subsp. paratuberculosis is strain dependent

Senthilkumar, P. Jagtap, S. Sreevatsan, 2010, BMC Microbiology.

The Wolbachia WO bacteriophage proteome in the Aedes albopictus C/wStr1 cell line: evidence for lytic activity?

A. Baldridge, B. Witthuhn, L. Higgins, 2015, In Vitro Cellular & Developmental Biology - Animal.

Phosphorylation and Activation of the DNA Binding Activity of Purified Stat1 by the Janus Protein-tyrosine Kinases and the Epidermal Growth Factor Receptor (*)

J. Ihle, F. Quelle, S. Cohen, 1995, The Journal of Biological Chemistry.

Detection of the Wolbachia-encoded DNA binding protein, HU beta, in mosquito gonads.

B. Witthuhn, A. Fallon, Todd W Markowski, 2013, Insect biochemistry and molecular biology.

Isolation and characterization of the rat β-subunit gene of the high affinity receptor for immunoglobulin E

B. Witthuhn, C. Faust, 1996 .