D. Burkin

发表

Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.

M. Ferrer, Noel Southall, Xin Hu, 2019, Human molecular genetics.

Laminin and alpha7beta1 integrin regulate agrin-induced clustering of acetylcholine receptors.

D. Burkin, S. Kaufman, J. E. Kim, 2000, Journal of cell science.

Enhanced Expression of the α7β1 Integrin Reduces Muscular Dystrophy and Restores Viability in Dystrophic Mice

Stephen J. Kaufman, Gregory Q. Wallace, D. Burkin, 2001, The Journal of cell biology.

The chromosomal distribution and organization of sheep satellite I and II centromeric DNA using characterized sheep-hamster somatic cell hybrids

D. Burkin, T. Broad, Carol A. Jones, 2005, Chromosome Research.

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy

D. Burkin, J. Rooney, Praveen B. Gurpur, 2009, Proceedings of the National Academy of Sciences.

Heart-specific overexpression of the human short CLC-3 chloride channel isoform limits myocardial ischemia-induced ERP and QT prolongation.

D. Duan, L. Ye, Yi‐Gang Li, 2016, International journal of cardiology.

Mapping of MYF5, C1R, MYHL, TPI1, IAPP, A2MR and RNR onto sheep chromosome 3q.

D. Burkin, C. Jones, T. Broad, 2009, Animal genetics.

Alpha7beta1-integrin regulates mechanotransduction and prevents skeletal muscle injury.

M. Boppart, D. Burkin, S. Kaufman, 2006, American journal of physiology. Cell physiology.

Activation of Volume Regulated Chloride Channels Protects Myocardium from Ischemia/reperfusion Damage in Second-window Ischemic Preconditioning

D. Duan, L. Ye, D. Burkin, 2011, Cellular Physiology and Biochemistry.

Increasing α7β1-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression

D. Burkin, S. Kaufman, Jianming Liu, 2008 .

Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy

J. Kornegay, R. Wuebbles, D. Burkin, 2013, Disease Models & Mechanisms.

Placental defects in α7 integrin null mice

D. Burkin, J. Welser, H. Burkin, 2007 .

Laminin and α 7 β 1 integrin regulate agrin-induced clustering of acetylcholine receptors

D. Burkin, S. Kaufman, M. Gu, 2000 .

The α7β1 integrin in muscle development and disease

D. Burkin, S. Kaufman, 1999, Cell and Tissue Research.

Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy.

M. Boppart, D. Burkin, S. Kaufman, 2011, Biochimica et biophysica acta.

Loss of the &agr;7 Integrin Promotes Extracellular Signal-Regulated Kinase Activation and Altered Vascular Remodeling

P. Scowen, C. Singer, W. Gerthoffer, 2007, Circulation research.

Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice.

Gregory Q. Wallace, E. Chaney, D. Milner, 2005, The American journal of pathology.

Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin.

D. Burkin, J. Welser, S. Kaufman, 2006, Journal of cell science.

Human laminin-111 and laminin-211 protein therapy prevents muscle disease progression in an immunodeficient mouse model of LAMA2-CMD

Pamela Barraza-Flores, D. Burkin, H. Hermann, 2020, Skeletal Muscle.

NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging

G. Lavery, D. Burkin, N. Mougenot, 2021, International journal of molecular sciences.

Localization and genomic organization of sheep antimicrobial peptide genes.

D. Burkin, K. Huttner, T. Broad, 1998, Gene.

The gene for the serpin thrombin inhibitor (PI7), protease nexin I, is located on human chromosome 2q33-q35 and on syntenic regions in the mouse and sheep genomes.

K. Cerosaletti, B. Greenberg, R. Fournier, 1995, Genomics.

-Integrin regulates mechanotransduction and prevents skeletal muscle injury

M. Boppart, D. Burkin, S. Kaufman, 2006 .

Mapping, sequence, and expression analysis of the human fertilin β gene (FTNB)

D. Griffin, D. Burkin, N. Affara, 1997 .

Bit‐1 is an essential regulator of myogenic differentiation

M. Jijiwa, M. Matter, J. Ramos, 2015, Journal of Cell Science.

The alpha7beta1 integrin in muscle development and disease.

D. Burkin, S. Kaufman, 1999, Cell and tissue research.

Alpha 7 integrin preserves the function of the extensor digitorum longus muscle in dystrophin-null mice.

Chady H Hakim, D. Duan, D. Burkin, 2013, Journal of applied physiology.

Six loci mapped on to human chromosome 2p are assigned to sheep chromosome 3p.

D. Burkin, L. Cambridge, C. Jones, 2009, Animal genetics.

Transgenic overexpression of α7 integrin in smooth muscle attenuates allergen‐induced airway inflammation in a murine model of asthma

C. Singer, R. Wuebbles, D. Burkin, 2022, FASEB bioAdvances.

Laminin-111 Improves the Anabolic Response to Mechanical Load in Aged Skeletal Muscle.

Heather D. Huntsman, M. C. Valero, K. Garg, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

Role for the α7β1 integrin in vascular development and integrity

P. Scowen, W. Hatton, D. Burkin, 2005 .

The muscle integrin binding protein (MIBP) interacts with α7β1 integrin and regulates cell adhesion and laminin matrix deposition

D. Burkin, S. Kaufman, Chuanyue Wu, 2003 .

Laminin and Integrin in LAMA2-Related Congenital Muscular Dystrophy: From Disease to Therapeutics

D. Burkin, C. R. Bates, P. Barraza-Flores, 2020, Frontiers in Molecular Neuroscience.

Myotendinous junction defects and reduced force transmission in mice that lack alpha7 integrin and utrophin.

C. Singer, D. Burkin, J. Welser, 2009, The American journal of pathology.

Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy.

Z. Yablonka-Reuveni, D. Burkin, J. Rooney, 2009, The American journal of pathology.

SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy.

Catherine Z. Chen, M. Ferrer, Noel Southall, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Commentary : SU 9516 increases α 7 β 1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy

Tatiana M. Fontelonga, A. Nunes, D. Burkin, 2017 .

Mesothelioma cells breaking bad: loss of integrin α7 promotes cell motility and poor clinical outcomes in patients

Tatiana M. Fontelonga, D. Burkin, Tatiana M Fontelonga, 2015, The Journal of pathology.

Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dyW mouse model of merosin-deficient congenital muscular dystrophy type 1A

Erika T. Allred, R. Wuebbles, D. Burkin, 2011, Journal of Cell Science.

Use of Grip Strength Meter to Assess the Limb Strength of dyw Mice

A. Connolly, K. Nagaraju, D. Burkin, 2013 .

Laminin-111 protein therapy enhances muscle regeneration and repair in the GRMD dog model of Duchenne muscular dystrophy.

J. Kornegay, A. Nunes, R. Wuebbles, 2019, Human molecular genetics.

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy

A. Nunes, R. Wuebbles, D. Burkin, 2017, Human molecular genetics.

Laminin-111 protein therapy reduces muscle pathology and improves viability of a mouse model of merosin-deficient congenital muscular dystrophy.

R. Wuebbles, D. Burkin, J. Rooney, 2012, The American journal of pathology.

Diagnosis and etiology of congenital muscular dystrophy

K. North, A. Compton, D. Burkin, 2008, Neurology.

A. Nunes, D. Burkin, A. Sarathy, 2017, Comprehensive Physiology.

Isolation of chromosome-specific paints from high-resolution flow karyotypes of the sheep (Ovis aries)

D. Hill, J. Wienberg, M. Ferguson-Smith, 1997, Chromosome Research.

Localization of the human indoleamine 2,3-dioxygenase (IDO) gene to the pericentromeric region of human chromosome 8.

D. Burkin, C. Jones, M. W. Taylor, 1993, Genomics.

Mapping the sheep genome: production of characterized sheep x hamster cell hybrids.

D. Burkin, C. Jones, T. Broad, 1993, Genomics.

Evaluation of the behavioral characteristics of the mdx mouse model of duchenne muscular dystrophy through operant conditioning procedures

D. Burkin, L. Hayes, K. Hunter, 2017, Behavioural Processes.

Seven loci on human Chromosome 4 map onto sheep Chromosome 6: a proposal to restore the original nomenclature of this sheep chromosome

D. Burkin, L. Cambridge, C. Jones, 1994, Mammalian Genome.

Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy.

R. Wuebbles, D. Burkin, P. V. Van Ry, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Use of the Indian muntjac idiogram to align conserved chromosomal segments in sheep and human genomes by chromosome painting.

D. Hill, J. Wienberg, M. Ferguson-Smith, 1997, Genomics.

Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice.

H. Tian, C. Singer, Mi Zhang, 2010, Journal of molecular and cellular cardiology.

Integrin α7: a major driver and therapeutic target for glioblastoma malignancy.

A. Nunes, D. Burkin, P. Barraza-Flores, 2017, Stem cell investigation.

Transgenic Expression of (cid:1) 7 (cid:2) 1 Integrin Maintains Muscle Integrity, Increases Regenerative Capacity, Promotes Hypertrophy, and Reduces Cardiomyopathy in Dystrophic Mice

Gregory Q. Wallace, E. Chaney, D. Milner, 2004 .

Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity

R. Bradley, G. Chew, R. Wuebbles, 2018, bioRxiv.

A Functional Role for Specific Spliced Variants of the α7β1 Integrin in Acetylcholine Receptor Clustering

D. Burkin, S. Kaufman, M. Gu, 1998, The Journal of cell biology.

212th ENMC International Workshop:: Animal models of congenital muscular dystrophies, Naarden, The Netherlands, 29–31 May 2015

Susan C. Brown, M. Girgenrath, C. Bönnemann, 2016, Neuromuscular Disorders.

Thirteen loci physically assigned to sheep Chromosome 2 by cell hybrid analysis and in situ hybridization

A. Gleeson, D. Burkin, C. Jones, 1995, Mammalian Genome.

A fast, novel approach for DNA fibre-fluorescence in situ hybridization analysis

D. Griffin, M. Ferguson-Smith, D. Burkin, 1997, Chromosome Research.

α7β1-Integrin regulates mechanotransduction and prevents skeletal muscle injury

M. Boppart, D. Burkin, S. Kaufman, 2006 .

Laminin-111 improves muscle repair in a mouse model of merosin-deficient congenital muscular dystrophy.

D. Burkin, B. Hodges, P. V. Van Ry, 2014, Human molecular genetics.

Role for the alpha7beta1 integrin in vascular development and integrity.

P. Scowen, W. Hatton, D. Burkin, 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

Tetrahydrobiopterin shifts the balance from oxidative stress to NO signalling in Duchenne muscular dystrophy

R. Wuebbles, D. Burkin, Ariany Oliveira-Santos, 2021, Acta physiologica.

Severe muscular dystrophy in mice that lack dystrophin and α7 integrin

D. Burkin, J. Welser, S. Kaufman, 2006, Journal of Cell Science.

Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice.

Jamie L. Marshall, D. Burkin, E. Chou, 2012, Human molecular genetics.

Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin.

Jamie L. Marshall, D. Burkin, J. Holmberg, 2015, Human molecular genetics.

Exercise promotes alpha7 integrin gene transcription and protection of skeletal muscle.

M. Boppart, D. Burkin, S. Kaufman, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

PTRH2 gene mutation causes progressive congenital skeletal muscle pathology

M. Jijiwa, M. Matter, J. Ramos, 2017, Human molecular genetics.

Valproic acid activates the PI3K/Akt/mTOR pathway in muscle and ameliorates pathology in a mouse model of Duchenne muscular dystrophy.

D. Burkin, S. Kaufman, Praveen B. Gurpur, 2009, The American journal of pathology.

Four human Chromosome 3q and four human Chromosome 21 loci map onto sheep Chromosome 1q

D. Burkin, L. Cambridge, C. Jones, 1995, Mammalian Genome.

Physical mapping confirms that sheep chromosome 10 has extensive conserved synteny with cattle chromosome 12 and human chromosome 13.

D. Burkin, C. Jones, T. Broad, 2009, Animal genetics.

Laminin-111 protein therapy after disease onset slows muscle disease in a mouse model of Laminin-α2 related congenital muscular dystrophy.

R. Grange, D. Burkin, Marisela Dagda, 2020, Human molecular genetics.

The alpha7 integrin subunit in astrocytes promotes endothelial blood-brain barrier integrity.

J. McCarty, D. Burkin, Arpan De, 2023, Development.

Integrin α7 Mutations Are Associated With Adult‐Onset Cardiac Dysfunction in Humans and Mice

H. Houlden, P. Syrris, B. Küsters, 2022, Journal of the American Heart Association.

Further cases of equine sex chromosome abnormalities.

D. Burkin, P. Pearce, I. A. Stewart-Scott, 1990, New Zealand veterinary journal.

The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition.

D. Burkin, S. Kaufman, Chuanyue Wu, 2003, Developmental biology.

Report on the Myomatrix Conference April 22–24, 2012, University of Nevada, Reno, Nevada, USA

M. Girgenrath, C. Bönnemann, M. Ruegg, 2013, Neuromuscular Disorders.

Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy

D. Burkin, Marisela Dagda, Ariany Oliveira-Santos, 2023, Disease Models & Mechanisms.

Physical assignment of loci to sheep Chromosome 7 confirms its homology to cattle Chromosome 10

D. Burkin, L. Cambridge, C. Jones, 1995, Mammalian Genome.

Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy

M. Girgenrath, C. Lutz, M. Rüegg, 2017, Journal of neuromuscular diseases.

Sheep CENPB and CENPC genes show a high level of sequence similarity and conserved synteny with their human homologs.

D. Burkin, C. Jones, T. Broad, 1996, Cytogenetics and cell genetics.

Commentary: SU9516 increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy

A. Nunes, D. Burkin, A. Sarathy, 2017, Journal of Rare Diseases Research & Treatment.

Increasing alpha 7 beta 1-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression.

D. Burkin, S. Kaufman, Jianming Liu, 2008, American journal of physiology. Cell physiology.

Assignment of five loci from human chromosome 8q onto sheep chromosome 9.

D. Burkin, L. Cambridge, C. Jones, 1995, Cytogenetics and cell genetics.

Human Galectin-1 Improves Sarcolemma Stability and Muscle Vascularization in the mdx Mouse Model of Duchenne Muscular Dystrophy

P. Brewer, R. Wuebbles, D. Burkin, 2019, Molecular therapy. Methods & clinical development.

CARDIAC‐SPECIFIC OVEREXPRESSION OF THE HUMAN SHORT CLC‐3 CHLORIDE CHANNEL ISOFORM IN MICE

P. Scowen, H. Tian, C. Singer, 2009, Clinical and experimental pharmacology & physiology.

A retooled drug that restores ionic balance and cardiac function in dystrophin deficient hearts.

R. Wuebbles, D. Burkin, 2020, International journal of cardiology.

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy

D. Burkin, J. Rooney, Praveen B. Gurpur, 2009, Proceedings of the National Academy of Sciences.

A Molecular Bandage for Diseased Muscle

R. Wuebbles, D. Burkin, 2012, Science Translational Medicine.

Report on the Myomatrix Conference April 22–24, 2012, University of Nevada, Reno, Nevada, USA

Susan C. Brown, M. Girgenrath, C. Bönnemann, 2013, Neuromuscular Disorders.

Molecular Pathogenesis of Genetic and Inherited Diseases Transgenic Expression of 7 1 Integrin Maintains Muscle Integrity, Increases Regenerative Capacity, Promotes Hypertrophy, and Reduces Cardiomyopathy in Dystrophic Mice

Gregory Q. Wallace, E. Chaney, D. Milner, 2004 .