Yuchen Du

发表

Functionally-defined Therapeutic Targets in Diffuse Intrinsic Pontine Glioma

Nicholas J. Wang, Noah E. Berlow, Matthew N. Svalina, 2015, Nature Medicine.

Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma

Steven J. M. Jones, Jessica M. Rusert, Richard A. Moore, 2020, Nature Neuroscience.

Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors.

C. Lau, Jianhua Yang, M. Chintagumpala, 2020, Cancer letters.

Maximizing the potential of aggressive mouse tumor models in preclinical drug testing

C. Lau, A. Erdreich-Epstein, K. Hui, 2021, Scientific Reports.

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.

Charles Y. Lin, D. Johnston, Hideo Nakamura, 2019, Cancer cell.

EPEN-02. Adaptive Convergence of Methylomes Reveals Epigenetic Drivers and Boosters of Repeated Relapses in Patient-matched Childhood Ependymomas and Identifies Targets for Anti-Recurrence Therapies

T. Man, Jianhua Yang, Yongcheng Song, 2021, Neuro-Oncology.

Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma

D. Parsons, J. Murray, C. Lau, 2017, Oncotarget.

Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models

Xiao-Nan Li, M. Qian, M. Kogiso, 2018, Clinical Cancer Research.

Evaluation of an EZH2 inhibitor in patient-derived orthotopic xenograft models of pediatric brain tumors alone and in combination with chemo- and radiation therapies

B. Teicher, Lei Guo, Malcolm A. Smith, 2021, Laboratory Investigation.

TIR-Domain-Containing Adapter-Inducing Interferon-β (TRIF) Is Essential for MPTP-Induced Dopaminergic Neuroprotection via Microglial Cell M1/M2 Modulation

Yuchen Du, Sen Lin, Yongmei Wu, 2017, Front. Cell. Neurosci..

Spatial and Temporal Distribution of Dopaminergic Neurons during Development in Zebrafish

Yuchen Du, Yongmei Wu, Haixia Zhao, 2016, Frontiers in neuroanatomy.

Large defects of type I allergic response in telomerase reverse transcriptase knockout mice

F. Ishikawa, K. Isobe, Aki Okada, 2007, Journal of leukocyte biology.

Systems biology–based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma

Stephen T. C. Wong, Hong Zhao, Huiyuan Zhang, 2018, Science Translational Medicine.

Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas

T. Man, Jianhua Yang, M. Chintagumpala, 2022, Nature Communications.

Analysis of growth hormone receptor polymorphism in Japanese semisuper centenarians

Y. Sakaki, K. Isobe, H. Inagaki, 2006 .

Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Ranadip Pal, Charles Keller, Nathalene Truffaux, 2015, Nature Medicine.

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma

Noah E. Berlow, Matthew N. Svalina, C. Hawkins, 2018, PloS one.

Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma

Yongcheng Song, M. Chintagumpala, Xiao-Nan Li, 2022, Translational oncology.

Prostaglandin E2 Induces MIR675-5p to Promote Colorectal Tumor Metastasis via Modulation of p53 Expression.

R. DuBois, D. Wang, Yuchen Du, 2019, Gastroenterology.

RETRACTED ARTICLE: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma

Jessica M. Rusert, M. Marra, N. Thiessen, 2020, Nature Neuroscience.

Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma

Jessica M. Rusert, Edwin F. Juarez, James D. Jensen, 2020, Cancer Research.

Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma

C. Keller, A. Harmanci, Akash J. Patel, 2020, Cancers.

Mislocalized cytoplasmic p27 activates PAK1‐mediated metastasis and is a prognostic factor in osteosarcoma

S. Jung, T. Man, J. Cates, 2019, Molecular oncology.

Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion

M. Kool, S. Pfister, S. Brabetz, 2021, Advanced science.

Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma

C. Lau, M. Chintagumpala, Xiao-Nan Li, 2016, Journal of Neuro-Oncology.

Cardiac Remodelling Following Cancer Therapy: A Review

Yuchen Du, Li Mingxi, Zhang Pengyan, 2022, Cardiovascular Toxicology.

Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

D. Brat, Xiao-Nan Li, M. Kogiso, 2022, Journal of Translational Medicine.

Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations

Ellen M. Langer, Amber N. Habowski, J. Kurhanewicz, 2024, Cancers.

Direct Implantation of Patient Brain Tumor Cells into Matching Locations in Mouse Brains for Patient-Derived Orthotopic Xenograft Model Development

T. Man, M. Kogiso, Yuchen Du, 2024, Cancers.

Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

D. Brat, Xiao-Nan Li, M. Kogiso, 2023, Journal of Translational Medicine.

In vitro vascular differentiation system efficiently produces natural killer cells for cancer immunotherapies

I. Balyasnikova, Yuchen Du, V. Galat, 2023, Oncoimmunology.

Fractionated radiation therapy alters energy metabolism and induces cellular quiescence exit in patient-derived orthotopic xenograft models of high-grade glioma.

M. Chintagumpala, Yuchen Du, A. Adesina, 2024, Translational oncology.