P. Hochman

发表

The structure of human interferon-β: implications for activity

A. Whitty, M. Karpusas, L. Runkel, 1998, Cellular and Molecular Life Sciences CMLS.

Improved pharmacokinetic properties of a polyethylene glycol-modified form of interferon-beta-1a with preserved in vitro bioactivity.

D. Baker, P. Hochman, R. Pepinsky, 2001, The Journal of pharmacology and experimental therapeutics.

Mapping of IFN-beta epitopes important for receptor binding and biologic activation: comparison of results achieved using antibody-based methods and alanine substitution mutagenesis.

D. Baker, A. Whitty, M. Zafari, 2001, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs

F. Mackay, J. Browning, P. Rennert, 1996, The Journal of experimental medicine.

Surface Lymphotoxin Tx/~ Complex Is Required for the Development of Peripheral Lymphoid Organs

F. Mackay, J. Browning, P. Rennert, 1996 .

Lymph Node Genesis Is Induced by Signaling through the Lymphotoxin β Receptor

F. Mackay, J. Browning, P. Rennert, 1998 .

Ligand-induced association of surface immunoglobulin with the detergent-insoluble cytoskeletal matrix of the B lymphocyte.

E. Unanue, P. Hochman, J. Braun, 1982, Journal of immunology.

Comparison of gene expression patterns induced by treatment of human umbilical vein endothelial cells with IFN-alpha 2b vs. IFN-beta 1a: understanding the functional relationship between distinct type I interferons that act through a common receptor.

A. Lukashin, A. Whitty, P. Hochman, 2002, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses

S. Bixler, R. Tizard, P. Hochman, 1993, The Journal of experimental medicine.

Mechanism of lymphocyte function-associated molecule 3-Ig fusion proteins inhibition of T cell responses. Structure/function analysis in vitro and in human CD2 transgenic mice.

D. Kioussis, P. Hochman, W. Meier, 1994, Journal of immunology.

The effects of an immunomodulatory LFA3-IgG1 fusion protein on nonhuman primates.

P. Hochman, C. A. Williams, W. Meier, 1994, Therapeutic immunology.

Short course single agent therapy with an LFA-3-IgG1 fusion protein prolongs primate cardiac allograft survival.

C. Marboe, R. Michler, P. Hochman, 1996, Transplantation.

Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice

F. Mackay, P. Lawton, J. Browning, 1997, European journal of immunology.

Lymphotoxin β Receptor Triggering Induces Activation of the Nuclear Factor κB Transcription Factor in Some Cell Types*

F. Mackay, J. Browning, P. Hochman, 1996, The Journal of Biological Chemistry.

Blockade of CD2-LFA-3 interactions protects human skin allografts in immunodeficient mouse/human chimeras

J. Pober, P. Askenase, J. McNiff, 1997, Nature Biotechnology.

Attenuated liver fibrosis in the absence of B cells.

M. Shlomchik, V. Koteliansky, S. Casola, 2005, The Journal of clinical investigation.

Costimulation by purified intercellular adhesion molecule 1 and lymphocyte function-associated antigen 3 induces distinct proliferation, cytokine and cell surface antigen profiles in human "naive" and "memory" CD4+ T cells

T. Nutman, P. Hochman, G. V. van Seventer, 1994, The Journal of experimental medicine.

Lymph node genesis is induced by signaling through the lymphotoxin beta receptor.

F. Mackay, J. Browning, P. Rennert, 1998, Immunity.

A Gene Conversion Event in the I-Aβb Gene Alters the Self-I-A Restricted T-Cell Repertoire of B6.C-H-2bm12 Mice

R. Flavell, G. Widera, P. Hochman, 1985 .

Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin-α–Deficient Mice

R. Flavell, D. Chaplin, J. Browning, 2001, The Journal of experimental medicine.

Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin- (cid:2) –deﬁcient Mice

R. Flavell, D. Chaplin, J. Browning, 2001 .

Recombinant ST2 boosts hepatic Th2 response in vivo

K. Gilbride, T. Novobrantseva, P. Hochman, 2007, Journal of leukocyte biology.

Molecular analysis of antigen recognition by insulin-specific T-cell hybridomas from B6 wild-type and bm12 mutant mice

R. Flavell, D. Sherman, B. Huber, 1987, Molecular and cellular biology.

Molecular Analysis ofAntigen Recognition byInsulin-Specific T-Cell Hybridomas fromB6Wild-Type andbml2MutantMice

P. Hochman, K. Ramachandran, 1987 .

Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.

C. Ambrose, C. Benjamin, P. Lawton, 1997, Journal of immunology.

Do Natural Killer Cells Engage in Regulated Reactions Against Self to Ensure Homeostasis?

P. Hochman, G. Cudkowicz, 1979, Immunological reviews.

Tests associés à un anti-vla-4

P. Hochman, T. Plavina, M. Lerner, 2010 .

Carrageenan-induced decline of natural killer activity. II. Inhibition of cytolysis by adherent non-T La-negative suppressor cells activated in vivo.

P. Hochman, P. Evans, G. Cudkowicz, 1981, Cellular immunology.

Alefacept, an Immunomodulatory Recombinant LFA-3/IgG1 Fusion Protein, Induces CD16 Signaling and CD2/CD16-Dependent Apoptosis of CD2+ Cells1

Yen-Ming Hsu, Y. Hsu, P. Hochman, 2002, The Journal of Immunology.

Immune recognition of insulin by H‐2b mice: the mutation in the I‐A βb gene of the B6.C‐H‐2bm12 mouse alters the self‐I‐A‐restricted T cell repertoire

B. Huber, P. Hochman, 1984, European journal of immunology.

Protection against Progressive Leishmaniasis by IFN-β1

C. Bogdan, J. Mattner, M. Röllinghoff, 2004, The Journal of Immunology.

Calculation of Electronic Spectra of Nonalternant Conjugated Hydrocarbons by the Semiempirical Method of Limited Configuration Interaction

J. Koutecký, J. Michl, P. Hochman, 1964 .

Carrageenan-induced decline of natural killer activity. I. In vitro activation of adherent non-T-suppressor cells.

P. Hochman, G. Cudkowicz, 1980, Cellular immunology.

Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts

G. Shearer, O. Haller, H. Wigzell, 1977, European journal of immunology.

Decline of natural killer cell activity in sublethally irradiated mice.

J Dausset, J. Dausset, P. Hochman, 1978, Journal of the National Cancer Institute.

Different sensitivities to hydrocortisone of natural killer cell activity and hybrid resistance to parental marrow grafts.

P. Hochman, G. Cudkowicz, 1977, Journal of immunology.

Suppression of natural cytotoxicity by spleen cells of hydrocortisone-treated mice.

P. Hochman, G. Cudkowicz, 1979, Journal of immunology.

Brief Definitive Report

J. Penninger, H. Scott, S. Parnell, 2003 .

Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization.

J. Browning, P. Rennert, P. Hochman, 1997, International immunology.

Characterization of a soluble ternary complex formed between human interferon‐β‐1a and its receptor chains

Wei Cheng, D. Baker, R. Arduini, 1999, Protein science : a publication of the Protein Society.

The structure of human interferon-beta: implications for activity.

A. Whitty, M. Karpusas, L. Runkel, 1998, Cellular and molecular life sciences : CMLS.

Cutting Edge: Germinal Centers Formed in the Absence of B Cell-Activating Factor Belonging to the TNF Family Exhibit Impaired Maturation and Function

Sambasiva P Rao, M. Scott, S. Kalled, 2003, The Journal of Immunology.

Proinflammatory responses are efficiently induced by homotrimeric but not heterotrimeric lymphotoxin ligands.

J L Browning, F. Mackay, J. Browning, 1995, Journal of inflammation.

B cell activation potential of insulin‐reactive T cells in H‐2b mice

B. Huber, P. Hochman, 1984, European journal of immunology.

Expression, purification, and characterization of rat interferon-beta, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters.

B. Domon, D. Baker, R. Arduini, 2004, Protein expression and purification.

Low affinity binding of an LFA-3/IgG1 fusion protein to CD2+ T cells is independent of cell activation.

A. Whitty, P. Hochman, W. Meier, 1999, Cell adhesion and communication.

CD 2 / CD 16-Dependent Apoptosis of CD 2 Induces CD 16 Signaling and Recombinant LFA-3 / IgG 1 Fusion Protein , Alefacept , an Immunomodulatory

Y. Hsu, P. Hochman, M. Brickelmaier, 2002 .

Immunomodulation by LFA3TIP, an LFA-3/IgG1 fusion protein: cell line dependent glycosylation effects on pharmacokinetics and pharmacodynamic markers.

M. Rogge, P. Hochman, A. Gill, 1995, Therapeutic immunology.

ELISA methods for the analysis of antibody responses induced in multiple sclerosis patients treated with recombinant interferon-beta.

A. Whitty, P. Hochman, M. Brickelmaier, 1999, Journal of immunological methods.

A novel murine model for the assessment of human CD2-related reagents in vivo.

J. Bromberg, P. Hochman, D. Fox, 1996, Journal of immunology.

Protection against progressive leishmaniasis by IFN-beta.

C. Bogdan, J. Mattner, M. Röllinghoff, 2004, Journal of immunology.

Amino acid residues required for binding of lymphocyte function- associated antigen 3 (CD58) to its counter-receptor CD2

E. Day, S. Meuer, R. Tizard, 1995, The Journal of experimental medicine.

Systematic mutational mapping of sites on human interferon-beta-1a that are important for receptor binding and functional activity.

A. Whitty, M. Zafari, C. Benjamin, 2000, Biochemistry.

Lymphotoxin beta receptor triggering induces activation of the nuclear factor kappaB transcription factor in some cell types.

F. Mackay, J. Browning, P. Hochman, 1996, The Journal of biological chemistry.

Quantification and Modeling of Tripartite CD2-, CD58FC Chimera (Alefacept)-, and CD16-mediated Cell Adhesion*

Daniel Coombs, Byron Goldstein, Adrian Whitty, 2007, Journal of Biological Chemistry.

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

B. Huber, P. Hochman, Cornelis J.H. Pronk, 2011, The Journal of experimental medicine.

A class II gene conversion event defines an antigen-specific Ir gene epitope

B. Huber, P. Hochman, 1984, The Journal of experimental medicine.