J. Bestwick

发表

Meta-Analysis of Early Nonmotor Features and Risk Factors for Parkinson Disease

A. Lees, A. Schrag, G. Giovannoni, 2012, Annals of neurology.

Randomised Trial of Text Messaging on Adherence to Cardiovascular Preventive Treatment (INTERACT Trial)

D. Wald, N. Wald, J. Bestwick, 2014, PloS one.

Combination Therapy Versus Monotherapy in Reducing Blood Pressure: Meta-analysis on 11,000 Participants from 42 Trials

D. Wald, M. Law, Joan K. Morris, 2010 .

Sequential and contingent prenatal screening for Down syndrome

A. Rudnicka, N. Wald, J. Bestwick, 2006, Prenatal diagnosis.

Maternal perchlorate levels in women with borderline thyroid function during pregnancy and the cognitive development of their offspring: data from the Controlled Antenatal Thyroid Study.

S. Channon, C. Hales, E. Pearce, 2014, The Journal of clinical endocrinology and metabolism.

Antenatal Screening for Hypothyroidism and Childhood Cognitive Impairment

N. Wald, S. Channon, J. Bestwick, 2013 .

Antenatal thyroid screening and childhood cognitive function.

N. Wald, S. Channon, R. Paradice, 2012, The New England journal of medicine.

Body weight reduction to avoid the excess risk of type 2 diabetes.

Joan K. Morris, N. Wald, J. Bestwick, 2012, The British journal of general practice : the journal of the Royal College of General Practitioners.

Familial hypercholesterolaemia: screening needs a fresh approach.

D. Wald, N. Wald, J. Bestwick, 2007, BMJ.

Combining Carotid Intima-media Thickness with Carotid Plaque on Screening for Coronary Heart Disease

D. Wald, N. Curzen, J. Bestwick, 2009, Journal of medical screening.

A Meta-Analysis of the Prevalence of Cardiac Valvulopathy in Patients With Hyperprolactinemia Treated With Cabergoline

W. Drake, R. Steeds, J. Bestwick, 2018, The Journal of clinical endocrinology and metabolism.

Preventive percutaneous coronary intervention and aspiration thrombectomy-updates in the management of ST-elevation myocardial infarction.

D. Wald, J. Bestwick, 2016, Journal of thoracic disease.

Preventive Percutaneous Coronary Intervention in ST-elevation Myocardial Infarction - The Primacy of Randomised Trials.

D. Wald, J. Bestwick, 2014, Interventional cardiology.

Randomized Crossover Trial of Phosphate-binding Medication on Serum Phosphate Levels in Patients With Aortic Stenosis

J. Chambers, D. Wald, N. Wald, 2019, Clinical therapeutics.

Maximising information on smell, quantitative motor impairment and probable REM-sleep behaviour disorder in the prediction of Parkinson’s disease

J. Cuzick, A. Lees, A. Schrag, 2020 .

Prenatal screening for Down syndrome in twin pregnancies: Estimates of screening performance based on 61 affected and 7302 unaffected twin pregnancies

N. Wald, J. Bestwick, A. Borrell, 2018, Prenatal diagnosis.

Child-Parent Familial Hypercholesterolemia Screening in Primary Care.

D. Wald, N. Wald, J. Bestwick, 2017, The New England journal of medicine.

Prenatal reflex DNA screening for Down syndrome: enhancing the screening performance of the initial first trimester test

N. Wald, J. Bestwick, Nicholas J. Wald, 2016, Prenatal diagnosis.

Sequential integrated antenatal screening for Down’s syndrome, trisomy 18 and trisomy 13

N. Wald, J. Bestwick, 2016, Journal of medical screening.

Antenatal reflex DNA screening for trisomy 18 and trisomy 13 in addition to Down’s syndrome

N. Wald, J. Bestwick, 2016, Journal of medical screening.

Child-Parent Familial Hypercholesterolemia Screening in Primary Care.

D. Wald, N. Wald, J. Bestwick, 2016, The New England journal of medicine.

Presentation of meta-analysis plots

N. Wald, J. Bestwick, JP Bestwick, 2015, Journal of medical screening.

Reflex antenatal DNA screening for Down syndrome

N. Wald, J. Bestwick, E. Peregrine, 2015, Prenatal diagnosis.

Performance of antenatal reflex DNA screening for Down’s syndrome

N. Wald, J. Bestwick, 2015, Journal of medical screening.

Incorporating DNA Sequencing into Current Prenatal Screening Practice for Down's Syndrome

N. Wald, J. Bestwick, 2013, PloS one.

Detection of trisomy 18 and trisomy 13 using first and second trimester Down's syndrome screening markers

N. Wald, J. Bestwick, W. Huttly, 2013, Journal of medical screening.

Allowing for ethnic group in antenatal screening for Down's syndrome

N. Wald, J. Bestwick, W. Huttly, 2013, Journal of medical screening.

Antenatal Screening for Down Syndrome Using Serum Placental Growth Factor with the Combined, Quadruple, Serum Integrated and Integrated Tests

N. Wald, J. Bestwick, L. George, 2012, PloS one.

F Child-Parent Screening for Familial Hypercholesterolemia

D. Wald, N. Wald, A. Kasturiratne, 2011 .

Child-parent screening for familial hypercholesterolemia.

D. Wald, N. Wald, A. Kasturiratne, 2011, The Journal of pediatrics.

Distribution of nuchal translucency in antenatal screening for Down's syndrome

N. Wald, J. Bestwick, W. Huttly, 2010, Journal of medical screening.

Antenatal screening for Down's syndrome using the Integrated test at two London hospitals

C. Rodeck, J. Bestwick, N. Wald, 2009, Journal of medical screening.

Setting truncation limits for marker values in medical screening

J. Bestwick, I. Barnes, S. O. Larsen, 2007, Journal of medical screening.

Validation plots in antenatal screening for Down's syndrome

N. Wald, J. Bestwick, J. Morris, 2006, Journal of medical screening.

Thyroid stimulating hormone and free thyroxine in pregnancy: expressing concentrations as multiples of the median (MoMs).

N. Wald, J. Bestwick, J. Lazarus, 2014, Clinica chimica acta; international journal of clinical chemistry.

Multi-marker risk-based screening for prostate cancer

N. Wald, J. Bestwick, J. Morris, 2022, Journal of medical screening.

Evaluation of stability of directly standardized rates for sparse data using simulation methods

J. Bestwick, P. Fryers, Joachim Tan, 2018, Population Health Metrics.

Reaching detection targets in familial hypercholesterolaemia: Comparison of identification strategies.

D. Wald, J. Bestwick, 2019, Atherosclerosis.

Scanning electron microscopy for blood micro-crystals in aortic stenosis patients

D. Wald, J. Bestwick, S. Bertazzo, 2018, PloS one.

Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm

J. Cuzick, A. Lees, A. Schrag, 2021, NPJ Parkinson's disease.

Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm

J. Cuzick, A. Lees, A. Schrag, 2020, NPJ Parkinson's disease.

Evolution and clustering of prodromal parkinsonian features in GBA1 carriers

A. Schapira, H. Zetterberg, A. McNeill, 2019, Movement disorders : official journal of the Movement Disorder Society.

The value of early second trimester PAPP-A and ADAM12 in screening for pre-eclampsia

N. Wald, J. Bestwick, L. George, 2012, Journal of medical screening.

Watchful Waiting in Aortic Stenosis: The Problem of Acute Decompensation.

D. Wald, J. Bestwick, Sam Williams, 2017, The American journal of medicine.

The relationship of cerebrospinal fluid neurofilament levels with magnetic resonance imaging lesion location and disease activity in multiple sclerosis

G. Giovannoni, A. Adams, J. Bestwick, 2022, European journal of neurology.

CONSTIPATION PRECEDING PARKINSON'S DISEASE–META-ANALYSIS

A. Lees, A. Schrag, S. Shribman, 2015, Journal of Neurology, Neurosurgery & Psychiatry.

Ethnic access to child–parent screening for familial hypercholesterolaemia

D. Wald, J. Bestwick, 2019, European journal of preventive cardiology.

Developing and Validating a New Web-Based Tapping Test for Measuring Distal Bradykinesia in Parkinson's Disease

A. Noyce, J. Bestwick, D. Gallagher, 2020, medRxiv.

Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population.

J. Cuzick, A. Lees, A. Schrag, 2022, JAMA neurology.

Prevention of Neural Tube Defects: A Cross-Sectional Study of the Uptake of Folic Acid Supplementation in Nearly Half a Million Women

N. Wald, J. Bestwick, W. Huttly, 2014, PloS one.

Specifying a Gold Standard for the Validation of Fetal Fraction Estimation in Prenatal Screening.

K. Lau, N. Wald, J. Bestwick, 2018, Clinical chemistry.

Prenatal reflex DNA screening for trisomies 21, 18, and 13

N. Wald, D. Roberts, Z. Alfirevic, 2018, Genetics in Medicine.

Risk factors and early non-motor features for Parkinson's disease: A systematic review and meta-analysis

Gavin Giovannoni, Alastair J. Noyce, Andrew J. Lees, 2012 .

Prenatal maternal plasma DNA screening for cystic fibrosis: A computer modelling study of screening performance

N. Wald, J. Bestwick, R. Old, 2017, F1000Research.

Incidence of cabergoline associated valvulopathy in primary care patients with prolactinoma using hard cardiac endpoints.

W. Drake, R. Steeds, G. Lloyd, 2020, The Journal of clinical endocrinology and metabolism.

English hepatitis C registry data show high response rates to directly acting anti‐virals, even if treatment is not completed

W. Gelson, A. Elsharkawy, G. Foster, 2020, Alimentary pharmacology & therapeutics.

Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases

Ludwig Kappos, Gavin Giovannoni, Axel Petzold, 2013, PloS one.

PREDICT-PD study: Online screening algorithm identifying Parkinson's disease risk

Alastair J. Noyce, Andrew J. Lees, John Hardy, 2013 .

Cost and efficacy comparison of prenatal recall and reflex DNA screening for trisomy 21, 18 and 13

N. Wald, J. Bestwick, 2019, PloS one.

Screening for pre-eclampsia using serum placental growth factor and endoglin with Down's syndrome Quadruple test markers

N. Wald, J. Bestwick, L. George, 2012, Journal of medical screening.

C-reactive protein measurement and cardiovascular disease

D. Wald, J. Bestwick, 2010, The Lancet.

A non-injected opioid analgesia protocol for acute pain crisis in adolescents and adults with sickle cell disease

J. Elander, J. Bestwick, B. Kaya, 2021, British journal of pain.

Alcohol and Parkinson's Disease: A Systematic Review and Meta-Analysis.

A. Noyce, J. Bestwick, Eleanor Mitchell, 2022, Journal of Parkinson's disease.

One-way versus two-way text messaging on improving medication adherence: meta-analysis of randomized trials.

D. Wald, J. Bestwick, Shahena Butt, 2015, The American journal of medicine.

Perchlorate and thiocyanate exposure and thyroid function in first-trimester pregnant women.

E. Pearce, L. Braverman, Xue-mei He, 2010, The Journal of clinical endocrinology and metabolism.

Antenatal screening for Down’s syndrome, trisomy 18, and trisomy 13: Reporting a single screening result for all three

N. Wald, J. Bestwick, 2015, Journal of medical screening.

Constipation preceding Parkinson's disease: a systematic review and meta-analysis

A. Lees, A. Schrag, S. Shribman, 2015, Journal of Neurology, Neurosurgery & Psychiatry.

Adherence to drugs that prevent cardiovascular disease: meta-analysis on 376,162 patients.

D. Wald, J. Bestwick, S. H. Naderi, 2012, The American journal of medicine.

Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome

L. Kappos, G. Giovannoni, N. Norgren, 2014, Journal of Neurology, Neurosurgery & Psychiatry.

Child-parent screening for familial hypercholesterolaemia: screening strategy based on a meta-analysis

D. Wald, N. Wald, J. Bestwick, 2007, BMJ : British Medical Journal.

Dementia risk in a diverse population: A single-region nested case-control study in the East End of London

J. Cuzick, G. Giovannoni, N. Mukadam, 2022, The Lancet regional health. Europe.

Gene-environment interactions in Multiple Sclerosis: a UK Biobank study

G. Giovannoni, A. Noyce, J. Bestwick, 2020, bioRxiv.

Retrospective observational comparative study of Hemilaminectomy versus Laminectomy for intraspinal tumour resection; Shorter Stays, Lower Analgesic Usage and Less Kyphotic Deformity

J. Bestwick, J. Brecknell, C. Millward, 2015, British journal of neurosurgery.

Slow Motion Analysis of Repetitive Tapping (SMART) Test: Measuring Bradykinesia in Recently Diagnosed Parkinson's Disease and Idiopathic Anosmia.

A. Lees, A. Schrag, C. Lambert, 2021, Journal of Parkinson's disease.

A simple method to allow for guanine-cytosine amplification error in prenatal DNA screening for trisomy 18.

K. Lau, N. Wald, J. Bestwick, 2019, Clinica chimica acta; international journal of clinical chemistry.

Prenatal reflex DNA screening for trisomies 21, 18, and 13

N. Wald, D. Roberts, Z. Alfirevic, 2018, Genetics in Medicine.

Association Between Antiepileptic Drugs and Incident Parkinson Disease in the UK Biobank.

A. Noyce, J. Bestwick, R. Dobson, 2022, JAMA neurology.

Patients’ attitudes towards the presence of medical students during consultations

J. Bestwick, A. Cushing, T. Choudhury, 2006, Medical teacher.

Genetic comorbidities in Parkinson's disease.

Mohamad Saad, Anette Schrag, Thomas Gasser, 2014, Human molecular genetics.

Type 2 Diabetes as a Determinant of Parkinson’s Disease Risk and Progression

Z. Gan-Or, A. Noyce, J. Bestwick, 2021, Movement disorders : official journal of the Movement Disorder Society.

Type 2 diabetes as a determinant of Parkinson's disease risk and progression.

Z. Gan-Or, A. Noyce, J. Bestwick, 2020, medRxiv.

Association between serum calcium, serum phosphate and aortic stenosis with implications for prevention

D. Wald, J. Bestwick, 2018, European journal of preventive cardiology.

Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features

J. Cuzick, A. Lees, A. Schrag, 2021, NPJ Parkinson's disease.

PREDICT‐PD: An online approach to prospectively identify risk indicators of Parkinson's disease

J. Hardy, A. Lees, A. Schrag, 2017, Movement disorders : official journal of the Movement Disorder Society.

Gender Differences in the Prevalence of Parkinson's Disease

C. Blauwendraat, A. Noyce, C. Marras, 2022, medRxiv.

Effect of interrupting prenatal Down syndrome screening due to a large nuchal translucency

Nicholas J Wald, J. Bestwick, Jonathan P Bestwick, 2012, Prenatal diagnosis.

The potential utility of smell testing to screen for neurodegenerative disorders

A. Noyce, J. Bestwick, Gregory R. Goodwin, 2022, Expert review of molecular diagnostics.

Metformin to reduce metabolic complications and inflammation in patients on systemic glucocorticoid therapy: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial.

I. Pernicova, M. Korbonits, A. Grossman, 2020, The lancet. Diabetes & endocrinology.

Multiple-marker screening for Down's syndrome: a method of assessing the statistical robustness of proposed tests

N. Wald, J. Bestwick, J. Morris, 2008, Journal of medical screening.

Ductus Venosus Pulsatility Index as an Antenatal Screening Marker for Down'S Syndrome: Use with the Combined and Integrated Tests

N. Wald, J. Bestwick, A. Borrell, 2009, Journal of medical screening.

Parkinson’s disease determinants, prediction and gene–environment interactions in the UK Biobank

M. Nalls, A. Singleton, C. Blauwendraat, 2020, Journal of Neurology, Neurosurgery, and Psychiatry.

Bone health in Parkinson's disease: a systematic review and meta-analysis

A. Lees, A. Noyce, J. Bestwick, 2014, Journal of Neurology, Neurosurgery & Psychiatry.

A comparative study of CSF neurofilament light and heavy chain protein in MS

L. Kappos, R. Lindberg, G. Giovannoni, 2013, Multiple sclerosis.

PREDICT-PD: Identifying risk of Parkinson's disease in the community: methods and baseline results

J. Hardy, A. Lees, A. Schrag, 2013, Journal of Neurology, Neurosurgery & Psychiatry.

The role of venous blood gas in the Emergency Department: a systematic review and meta-analysis

J. Bestwick, T. Harris, B. Bloom, 2014, European journal of emergency medicine : official journal of the European Society for Emergency Medicine.

Gene-Environment Interactions in Multiple Sclerosis

G. Giovannoni, A. Noyce, J. Bestwick, 2021, Neurology: Neuroimmunology & Neuroinflammation.

A 16-week, randomized, double-blind, placebo-controlled, crossover trial to quantify the combined effect of an angiotensin-converting enzyme inhibitor and a beta-blocker on blood pressure reduction.

D. Wald, M. Law, N. Wald, 2008, Clinical therapeutics.

hypothyroidism A randomized double-blind crossover trial to investigate the efficacy of screening for adult

N. Wald, J. Bestwick, M. Abu-Helalah, 2013 .

A randomized double-blind crossover trial to investigate the efficacy of screening for adult hypothyroidism

M. Law, N. Wald, J. Bestwick, 2010, Journal of medical screening.

The value of C-reactive protein in screening for future coronary heart disease events

D. Wald, A. Kasturiratne, J. Bestwick, 2009, Journal of medical screening.

Should Fractional Flow Reserve follow Angiographic Visual Inspection to guide Preventive PCI in STEMI?

D. Wald, J. Bestwick, S. Hadyanto, 2020, European heart journal. Quality of care & clinical outcomes.

Prevalence of DNA-confirmed familial hypercholesterolaemia in young patients with myocardial infarction.

D. Wald, J. Bestwick, F. Bangash, 2015, European journal of internal medicine.

Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson’s disease: a Distal Finger Tapping test

A. Schrag, A. Noyce, J. Bestwick, 2022, Scientific Reports.

COVID-19 vaccine response in people with multiple sclerosis.

K. Schmierer, Angray S. Kang, N. Evangelou, 2021, Annals of neurology.

First trimester Down's syndrome screening marker values and cigarette smoking: new data and a meta-analysis on free β human chorionic gonadotophin, pregnancy-associated plasma protein-A and nuchal translucency

N. Wald, J. Bestwick, W. Huttly, 2008, Journal of medical screening.

Three stage contingent screening for Down syndrome

P. Pandya, N. Wald, J. Bestwick, 2006, Prenatal diagnosis.

Slow Motion Analysis of Repetitive Tapping (SMART) test: measuring bradykinesia in recently diagnosed Parkinson's disease and idiopathic anosmia

A. Lees, A. Schrag, C. Lambert, 2021, medRxiv.

Cross‐trimester marker ratios in prenatal screening for Down syndrome

N. Wald, J. Bestwick, J. Morris, 2006, Prenatal Diagnosis.

Carotid Ultrasound Screening for Coronary Heart Disease: Results Based on a meta-analysis of 18 Studies and 44,861 Subjects

D. Wald, J. Bestwick, 2009, Journal of medical screening.

Truncation limits for CT marker ratios in prenatal screening for Down syndrome

N. Wald, J. Bestwick, J. Morris, 2007, Prenatal diagnosis.

Cross trimester marker ratios: parameter estimates valid with no inconsistency

N. Wald, J. Bestwick, J. Morris, 2006 .

Should fractional flow reserve follow angiographic visual inspection to guide preventive percutaneous coronary intervention in ST-elevation myocardial infarction?

D. Wald, J. Bestwick, S. Hadyanto, 2020 .

Modifiable Risk Factors for Multiple Sclerosis are Consistent Across Diverse Ethnic Backgrounds: A Nested Case-Control Study in a UK Population-Based Cohort

G. Giovannoni, A. Noyce, J. Bestwick, 2022, Social Science Research Network.

Subtle motor disturbances in PREDICT-PD participants

A. Lees, A. Schrag, G. Giovannoni, 2016, Journal of Neurology, Neurosurgery & Psychiatry.

Bradykinesia-Akinesia Incoordination Test: Validating an Online Keyboard Test of Upper Limb Function

Gavin Giovannoni, Alastair J. Noyce, Andrew J. Lees, 2013, PloS one.

Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson’s disease: a Distal Finger Tapping test

A. Schrag, A. Noyce, J. Bestwick, 2022, Scientific Reports.

Dopamine reuptake transporter–single‐photon emission computed tomography and transcranial sonography as imaging markers of prediagnostic Parkinson's disease

M. Politis, A. Schrag, G. Giovannoni, 2018, Movement disorders : official journal of the Movement Disorder Society.

A systematic review and meta-analysis of return to work after mild Traumatic brain injury

R. Pearse, A. Fowler, J. Bestwick, 2018, Brain injury.

Improvements in antenatal screening for Down's syndrome

N. Wald, J. Bestwick, W. Huttly, 2013, Journal of medical screening.

Insulin dependent diabetes mellitus (IDDM) and first trimester markers in prenatal screening for Down syndrome

N. Wald, J. Bestwick, W. Huttly, 2016, Prenatal diagnosis.

Prenatal reflex DNA screening for trisomies 21, 18, and 13

N. Wald, D. Roberts, Z. Alfirevic, 2017, Genetics in Medicine.

Response to Walker

N. Wald, D. Roberts, Z. Alfirevic, 2018, Genetics in Medicine.

Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

S. Rauch, C. Enzinger, X. Montalban, 2015, Multiple sclerosis.

Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials.

D. Wald, M. Law, N. Wald, 2009, The American journal of medicine.

Unconjugated estriol values between 14 and 22 weeks of gestation in relation to prenatal screening for Down syndrome

N. Wald, J. Bestwick, W. Huttly, 2012, Prenatal diagnosis.

Inhibin‐A concentrations between 14 and 22 weeks of gestation

N. Wald, J. Bestwick, W. Huttly, 2008, Prenatal diagnosis.

The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease

P. Mahlknecht, A. Schrag, G. Giovannoni, 2023, Movement disorders : official journal of the Movement Disorder Society.

Constipation preceding Parkinson's disease: a systematic review and meta-analysis

S. Shribman, A. Noyce, J. Bestwick, 2015, Journal of Neurology, Neurosurgery & Psychiatry.

Homocysteine as a cause of ischemic heart disease: the door remains open.

D. Wald, N. Wald, J. Bestwick, 2012, Clinical chemistry.

The area under the ROC curve: Is it a valid measure of screening performance?

N. Wald, J. Bestwick, 2014, Journal of medical screening.

Preventive Percutaneous Coronary Intervention in ST-elevation Myocardial Infarction - The Primacy of Randomised Trials.

D. Wald, J. Bestwick, 2014, Interventional cardiology.

Web‐based assessment of Parkinson's prodromal markers identifies GBA variants

A. Schrag, G. Giovannoni, N. Mencacci, 2015, Movement disorders : official journal of the Movement Disorder Society.

Web Application to Enable Online Social Interactions in a Parkinson Disease Risk Cohort: Feasibility Study and Social Network Analysis

J. Bestwick, A. De Simoni, Xiancheng Li, 2023, JMIR formative research.

Modifiable risk factors for multiple sclerosis have consistent directions of effect across diverse ethnic backgrounds: a nested case–control study in an English population-based cohort

R. Mathur, A. Noyce, J. Bestwick, 2023, Journal of neurology.