Bailin Zhang

发表

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.

A. Iafrate, K. Flaherty, H. Wakimoto, 2015, Cancer cell.

Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

D. Wiederschain, C. Winter, J. Pollard, 2017, PloS one.

A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells

G. Nabel, D. Wiederschain, Huawei Qiu, 2022, Nature.

Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells

Q. Zhan, Yongmei Song, Y-X Ou, 2013, Cancer Biology & Therapy.

Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer.

W. Tan, D. Lin, Dianke Yu, 2007, Carcinogenesis.

Single molecular recognition force spectroscopy study of a luteinizing hormone-releasing hormone analogue as a carcinoma target drug.

Jilin Tang, P. Zhu, P. Hinterdorfer, 2012, The journal of physical chemistry. B.

PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA

Wen Tan, Zexian Liu, Xudong Huang, 2019, Molecular Cancer.

Hepatic glycogen cycling contributes to glucose lowering effects of the glucokinase activator LCZ960.

J Zhang, A. Duttaroy, Jiaping Gao, 2013, European journal of pharmacology.

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Dietmar Hoffmann, Jean-Pierre Marquette, Magali Mathieu, 2014, The Journal of Biological Chemistry.

Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model

F. Buckner, E. Merritt, A. Paredez, 2019, bioRxiv.

Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.

Q. Gao, I. Cornella-Taracido, C. García-echeverría, 2018, Cell chemical biology.

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

Jeffrey P. MacKeigan, Charles Kung, Bailin Zhang, 2009, Cell.

Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes

W. Liu, Yunping Luo, Bailin Zhang, 2019, Scientific Reports.

Yi Zhang, Yipeng Wang, Lin Feng, 2021, American Journal of Cancer Research.

Extreme Vulnerability of ID H 1 Mutant Cancers to NAD + Depletion Graphical Abstract Highlights

A. Iafrate, K. Flaherty, H. Wakimoto, 2022 .

Towards prediction of in vivo intestinal absorption using a 96-well Caco-2 assay.

Xuena Lin, S. Skolnik, Bailin Zhang, 2010, Journal of pharmaceutical sciences.

Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration

D. Rajpal, Virginia Savova, Yingnan Han, 2022, Nature Neuroscience.

PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene.

S. Gross, Q. Gao, D. Wiederschain, 2014, Blood.

suppression of STAT 5 activation and degradation of MYC oncogene PIM inhibitors target CD 25-positive AML cells through concomitant

S. Gross, Q. Gao, D. Wiederschain, 2014 .

Regulation of the MicroRNA 200b (miRNA-200b) by Transcriptional Regulators PEA3 and ELK-1 Protein Affects Expression of Pin1 Protein to Control Anoikis*

Zhihua Liu, Bailin Zhang, Ji-dong Gao, 2013, The Journal of Biological Chemistry.

PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA

W. Tan, D. Lin, Xudong Huang, 2019, Molecular Cancer.

PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling.

Jeffrey A. Porter, P. De Camilli, T. Bouwmeester, 2013, Chemistry & biology.

Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer

Q. Zhan, Yongmei Song, Weimin Zhang, 2019, Theranostics.

Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches

Q. Gao, D. Wiederschain, C. García-echeverría, 2013, The Journal of Biological Chemistry.

An early signaling GARP transcription factor regulates the entry point for differentiation in Giardia

B. Kerr, A. Paredez, Bailin Zhang, 2021 .

Loss of TTC17 promotes breast cancer metastasis through RAP1/CDC42 signaling and sensitizes it to rapamycin and paclitaxel

Bailin Zhang, Yang Wang, H. Qian, 2023, Cell & Bioscience.

Anti‐CD38 monoclonal antibody interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping

M. Chiron, F. Pirenne, O. Bedel, 2022, Transfusion.

Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells

E. Li, Taiping Chen, Bailin Zhang, 2007, Nature Genetics.

Metal Binding Network by an Allosteric Dehydrogenase 1 ( IDH 1 ) via Disruption of Selective Inhibition of Mutant Isocitrate Enzymology

S. Gross, Q. Gao, D. Wiederschain, 2014 .

Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

G. Nabel, M. Chiron, Huawei Qiu, 2019, Nature Cancer.

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

Thomas Bertrand, Bailin Zhang, Lionel Bert, 2015, Scientific Reports.

Regulation of the miRNA-200 b by transcriptional regulators PEA 3 and ELK-1 affects expression of Pin 1 to control anoikis

Zhihua Liu, Bailin Zhang, Ji-dong Gao, 2013 .

Microglia ferroptosis is prevalent in neurodegenerative disease and regulated by SEC24B

D. Rajpal, Bailin Zhang, D. Ofengeim, 2021 .

Incremental biomarker and clinical outcomes after switch from enzyme therapy to eliglustat substrate reduction therapy in Gaucher disease

Haiqun Lin, P. Mistry, V. Murugesan, 2021, Molecular genetics and metabolism reports.

Evaluation of Fluorescence- and Mass Spectrometry—Based CYP Inhibition Assays for Use in Drug Discovery

Laszlo Urban, Bailin Zhang, Dejan Bojanic, 2008, Journal of biomolecular screening.

Abstract A226: Mechanism of action of iniparib: Stimulation of reactive oxygen species (ROS) production in an iniparib-sensitive breast cancer cell line.

D. Bergstrom, J. Watters, J. Pollard, 2011 .

Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer’s disease

G. Nabel, T. Taksir, Bailin Zhang, 2019, PloS one.

Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells

Madelyn Light, Q. Gao, D. Wiederschain, 2014, Nucleic acids research.

Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections

J. Mascola, M. Connors, R. Koup, 2023, Nature communications.

[1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding.

D. Chin, W. Shao, Yun Feng, 2012, Journal of medicinal chemistry.

A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities

R. Gregory, S. Licht, P. Ferrari, 2018, SLAS discovery : advancing life sciences R & D.

Single molecular recognition force spectroscopy study of a luteinizing hormone-releasing hormone analogue as a carcinoma target drug.

Jilin Tang, P. Zhu, P. Hinterdorfer, 2012, The journal of physical chemistry. B.

Abstract 1632: Antibody mediated crosslinking of CD38 triggers costimulatory signaling and promotes T cell effector function

Mun Kyung Hwang, D. Wiederschain, Shujia Dai, 2021, Immunology.

Abstract 5468: SAR650984, a humanized anti-CD38 antibody potently modulates intracellular and extracellular nucleotide levels of cancer cells

Shujia Dai, T. Cai, S. Licht, 2014 .