A. Singh

发表

MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells.

J. Meza, P. Singh, S. Batra, 2008, Cancer research.

Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.

Ganesh Venkatraman, James D Eudy, Sangeeta Bafna, 2008, Cancer letters.

Penetratin improves tumor retention of single-chain antibodies: a novel step toward optimization of radioimmunotherapy of solid tumors.

S. Batra, Maneesh Jain, S. Chauhan, 2005, Cancer research.

microRNAs in Cancer Stem Cells: Micromanagers of Malignancy

S. Arora, A. Singh, A. Bhardwaj, 2013 .

Exploiting Nanotechnology for the Development of MicroRNA-Based Cancer Therapeutics.

S. Arora, A. Singh, Saravanakumar Marimuthu, 2016, Journal of biomedical nanotechnology.

MicroRNAs: Emerging Novel Targets of Cancer Therapies

F. Takeshita, Yiguo Jiang, Chengfeng Yang, 2015, BioMed research international.

Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2019, Scientific Reports.

Synergistic induction of the MUC4 mucin gene by interferon-γ and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways

J. Meza, S. Batra, A. Agrawal, 2005, Oncogene.

Clinicopathologic significance and race-specific prognostic association of MYB overexpression in ovarian cancer

Karan P. Singh, Mohammad Aslam Khan, H. Ndetan, 2021, Scientific Reports.

Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer.

S. Batra, Maneesh Jain, M. P. Ponnusamy, 2008, The Lancet. Oncology.

MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin*

S. Arora, A. Singh, S. Srivastava, 2016, The Journal of Biological Chemistry.

Racial health disparities in ovarian cancer: not just black and white

Aamir Ahmad, A. Singh, S. Srivastava, 2017, Journal of Ovarian Research.

MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells.

Sumit Arora, William E Grizzle, Bin Wang, 2011, Carcinogenesis.

Award Number: W81XWH-09-1-0137 TITLE: Protein Phosphatase 2A Signaling in Human Prostate Cancer

W. Grizzle, E. Reed, S. Arora, 2012 .

MUC 4 Mucin Interacts with and Stabilizes the HER 2 Oncoprotein in Human Pancreatic Cancer Cells

J. Meza, P. Singh, S. Batra, 2008 .

Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy.

S. Batra, P. Chaturvedi, A. Singh, 2007, Cancer research.

Cigarette Smoke-induced Differential Expression of the Genes Involved in Exocrine Function of the Rat Pancreas

S. Batra, U. Wittel, M. Andrianifahanana, 2006, Pancreas.

Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer

S. Arora, Mohammad Aslam Khan, A. Singh, 2020, The Journal of Biological Chemistry.

Mitochondrial fusion and fission: The fine‐tune balance for cellular homeostasis

S. Dasgupta, A. Singh, Seema Singh, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

An Undesired Effect of Chemotherapy

G. Piazza, W. Grizzle, S. Arora, 2013, The Journal of Biological Chemistry.

The prevalence and clinical relevance of 2R/2R TYMS genotype in patients with gastrointestinal malignancies treated with fluoropyrimidine-based chemotherapy regimens

G. McMillin, P. Hosein, A. Singh, 2021, The Pharmacogenomics Journal.

The Prevalence of DPYD*9A(c.85T>C) Genotype and the Genotype-Phenotype Correlation in Patients with Gastrointestinal Malignancies Treated With Fluoropyrimidines: Updated Analysis.

W. Taylor, G. McMillin, S. Pai, 2019, Clinical colorectal cancer.

Mitochondrial respiratory complexes: Significance in human mitochondrial disorders and cancers

A. Singh, S. Dasgupta, Seema Singh, 2022, Journal of cellular physiology.

CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB

W. Grizzle, M. Kadakia, S. Arora, 2012, The Journal of Biological Chemistry.

CXCL12/CXCR4 signaling axis induces SHH expression in pancreatic cancer cells via ERK- and Akt- mediated activation of NF-κB: implications for bidirectional tumor-stromal interactions

W. Grizzle, M. Kadakia, S. Arora, 2012 .

Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation

A. Singh, Saravanakumar Marimuthu, S. Srivastava, 2015, Oncotarget.

Distribution of microbiota in cervical preneoplasia of racially disparate populations

J. Pierce, A. Singh, S. Dasgupta, 2022, BMC Cancer.

MYB interacts with androgen receptor, sustains its ligand-independent activation and promotes castration resistance in prostate cancer

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2021, British Journal of Cancer.

Detection of mitochondrial DNA mutations in circulating mitochondria-originated extracellular vesicles for potential diagnostic applications in pancreatic adenocarcinoma

Mohammad Aslam Khan, A. Singh, S. Dasgupta, 2022, Scientific Reports.

Extracellular Nanovesicles: From Intercellular Messengers to Efficient Drug Delivery Systems

Mohammad Aslam Khan, A. Singh, Seema Singh, 2021, ACS omega.

Germline pharmacogenomics of DPYD*9A (c.85T>C) variant in patients with gastrointestinal malignancies treated with fluoropyrimidines.

W. Taylor, P. Hosein, A. Singh, 2018, Journal of gastrointestinal oncology.

Exosomal Formulation Escalates Cellular Uptake of Honokiol Leading to the Enhancement of Its Antitumor Efficacy

Mohammad Aslam Khan, Rajashekhar Kanchanapally, A. Singh, 2020, ACS omega.

Molecular Targets of Honokiol: A Promising Phytochemical for Effective Cancer Management.

S. Arora, A. Singh, H. Zubair, 2014, The Enzymes.

Modulation of the tumor microenvironment by natural agents: implications for cancer prevention and therapy.

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2020, Seminars in cancer biology.

Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance.

W. Grizzle, E. Reed, S. Arora, 2012, Carcinogenesis.

Phylogenetic relationships as in Ocimum revealed by RAPD markers

Vandana Singh, A. Singh, S. Khanuja, 2004, Euphytica.

CXCL8 and its cognate receptors in melanoma progression and metastasis.

Rakesh K. Singh, A. Singh, Seema Singh, 2010, Future oncology.

Shaping Up the Tumor Microenvironment: Extracellular Vesicles as Important Intermediaries in Building a Tumor-Supportive Cellular Network

A. Singh, Amod Sharma, Seema Singh, 2023, Cancers.

Current and Futuristic Roadmap of Ovarian Cancer Management: An Overview.

A. Singh, S. Srivastava, S. Dasgupta, 2021, Advances in experimental medicine and biology.

MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells.

J. Meza, S. Batra, A. Singh, 2008, Cancer research.

Epigenetic basis of cancer health disparities: Looking beyond genetic differences.

James E Carter, Aamir Ahmad, Mohammad Aslam Khan, 2017, Biochimica et biophysica acta. Reviews on cancer.

Mobilization of Intracellular Copper by Gossypol and Apogossypolone Leads to Reactive Oxygen Species-Mediated Cell Death: Putative Anticancer Mechanism

Aamir Ahmad, Daocheng Wu, M. Ullah, 2016, International journal of molecular sciences.

Structure, evolution, and biology of the MUC4 mucin

S. Batra, P. Chaturvedi, A. Singh, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of MUC4 Expression Suppresses Pancreatic Tumor Cell Growth and Metastasis

J. Meza, S. Batra, S. Chauhan, 2004, Cancer Research.

Emerging evidence for the role of differential tumor microenvironment in breast cancer racial disparity: a closer look at the surroundings

Aamir Ahmad, A. Singh, S. Srivastava, 2017, Carcinogenesis.

Epigallocatechin Gallate-Gold Nanoparticles Exhibit Superior Antitumor Activity Compared to Conventional Gold Nanoparticles: Potential Synergistic Interactions

Rajashekhar Kanchanapally, S. Chavva, A. Singh, 2019, Nanomaterials.

Cellular and Molecular Progression of Prostate Cancer: Models for Basic and Preclinical Research

S. Pai, A. Singh, S. Dasgupta, 2020, Cancers.

Therapies Targeted to Androgen Receptor Signaling Axis in Prostate Cancer: Progress, Challenges, and Hope

S. Pai, A. Singh, S. Srivastava, 2019, Cancers.

Phytochemicals, microRNAs, and Cancer: Implications for Cancer Prevention and Therapy

S. Arora, A. Singh, S. Srivastava, 2013 .

p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway

A. Singh, S. McClellan, A. Bhardwaj, 2014, Oncotarget.

MicroRNA-based Cancer Therapeutics: Big Hope from Small RNAs.

A. Singh, A. Bhardwaj, Seema Singh, 2010, Molecular and cellular pharmacology.

Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2022, The Journal of biological chemistry.

Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward

Mohammad Aslam Khan, A. Singh, H. Zubair, 2017, International journal of molecular sciences.

Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer

Aamir Ahmad, A. Singh, S. Srivastava, 2016, Scientific Reports.

MYB is a novel regulator of pancreatic tumour growth and metastasis

S. Arora, A. Singh, S. Srivastava, 2015, British Journal of Cancer.

Inflammation, immunosuppressive microenvironment and breast cancer: opportunities for cancer prevention and therapy.

A. Singh, S. Srivastava, Seema Singh, 2019, Annals of translational medicine.

Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carcinogenesis.

S. Arora, A. Singh, S. Srivastava, 2016, Cancer letters.

Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis

S. Arora, A. Singh, Saravanakumar Marimuthu, 2015, Scientific Reports.

Cancer Stem Cells

A. Singh, Saravanakumar Marimuthu, S. Srivastava, 2016 .

CXCR1 and CXCR2 silencing modulates CXCL8-dependent endothelial cell proliferation, migration and capillary-like structure formation.

Rakesh K. Singh, A. Singh, Seema Singh, 2011, Microvascular research.

Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2017, British Journal of Cancer.

MUC4 (mucin 4, cell surface associated)

S. Batra, P. Chaturvedi, A. Singh, 2011 .

Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival

Mohammad Aslam Khan, A. Singh, H. Zubair, 2020, Journal of cellular biochemistry.

Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2019, Scientific Reports.

Aberrant expression of MUC4 in ovarian carcinoma: diagnostic significance alone and in combination with MUC1 and MUC16 (CA125)

Lynette M. Smith, S. Batra, Maneesh Jain, 2006, Modern Pathology.

MUC4 Mucin Potentiates Pancreatic Tumor Cell Proliferation, Survival, and Invasive Properties and Interferes with Its Interaction to Extracellular Matrix Proteins

Jane L Meza, J. Meza, S. Batra, 2007, Molecular Cancer Research.

Modulation of MicroRNAs by Phytochemicals in Cancer: Underlying Mechanisms and Translational Significance

S. Arora, A. Singh, S. Srivastava, 2015, BioMed research international.

p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling

A. Singh, Saravanakumar Marimuthu, S. Srivastava, 2015, Cancer letters.

Mitochondrial Alterations in Prostate Cancer: Roles in Pathobiology and Racial Disparities

A. Singh, S. Dasgupta, Amod Sharma, 2023, International journal of molecular sciences.

Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis.

S. Arora, S. Palanki, M. Miller, 2015, Nanomedicine : nanotechnology, biology, and medicine.

ETV4: an emerging target in pancreatic cancer

A. Singh, Seema Singh, S. Deshmukh, 2018, Oncoscience.

Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.

Aamir Ahmad, S. Arora, Mohammad Aslam Khan, 2016, Carcinogenesis.

Epigenetic Control of Pancreatic Carcinogenesis and Its Regulation by Natural Products

Aamir Ahmad, S. Pai, Mohammad Aslam Khan, 2019, Epigenetics of Cancer Prevention.

Resistin: An inflammatory cytokine with multi-faceted roles in cancer.

A. Singh, Seema Singh, D. Dyess, 2020, Biochimica et biophysica acta. Reviews on cancer.

CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1

S. Arora, A. Singh, S. Srivastava, 2014, Oncotarget.

Characterization of Human Mucin MUC17

S. Batra, A. Singh, Nicolas Moniaux, 2006, Journal of Biological Chemistry.

Comprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic Cancer

Mohammad Aslam Khan, A. Singh, S. Anand, 2020, International journal of molecular sciences.

Platinum-resistant ovarian cancer: from drug resistance mechanisms to liquid biopsy-based biomarkers for disease management.

Mohammad Aslam Khan, A. Singh, S. Dasgupta, 2021, Seminars in cancer biology.

ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1

Aamir Ahmad, A. Singh, S. Srivastava, 2017, Molecular Cancer Research.

Proteomic analysis of MYB-regulated secretome identifies functional pathways and biomarkers: potential pathobiological and clinical implications.

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2020, Journal of proteome research.

Exosomal Markers (CD63 and CD9) Expression Pattern Using Immunohistochemistry in Resected Malignant and Nonmalignant Pancreatic Specimens.

W. Taylor, A. Singh, G. Patel, 2017, Pancreas.

Nicotine causes alternative polarization of macrophages via Src‐mediated STAT3 activation: Potential pathobiological implications

Mohammad Aslam Khan, A. Singh, Seema Singh, 2021, Journal of cellular physiology.

Insights into the Role of microRNAs in Pancreatic Cancer Pathogenesis: Potential for Diagnosis, Prognosis, and Therapy.

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2015, Advances in experimental medicine and biology.

Modulation of Protein Phosphatase 2A Activity Alters Androgen-Independent Growth of Prostate Cancer Cells: Therapeutic Implications

Eddie Reed, Arun Bhardwaj, E. Reed, 2011, Molecular Cancer Therapeutics.

Expression of TAG-72 in ovarian cancer and its correlation with tumor stage and patient prognosis.

S. Batra, Maneesh Jain, M. P. Ponnusamy, 2007, Cancer letters.

MUC 4 Mucin Potentiates Pancreatic Tumor Cell Proliferation , Survival , and Invasive Properties and Interferes with Its Interaction to Extracellular Matrix Proteins

J. Meza, S. Batra, P. Chaturvedi, 2007 .

Biological basis of cancer health disparities: resources and challenges for research.

Aamir Ahmad, A. Singh, H. Zubair, 2017, American journal of cancer research.

Glucose Metabolism Reprogrammed by Overexpression of IKKε Promotes Pancreatic Tumor Growth.

Aamir Ahmad, S. Arora, Mohammad Aslam Khan, 2016, Cancer research.

MicroRNAs in gynecological cancers: Small molecules with big implications.

Aamir Ahmad, A. Singh, J. Scalici, 2017, Cancer letters.

MicroRNAs in pancreatic malignancy: progress and promises.

S. Arora, A. Singh, S. Srivastava, 2014, Cancer letters.

Ovarian Carcinoma: Diagnostic Immunohistochemistry of MUCIN4 (MUC4)

S. Batra, M. P. Ponnusamy, S. Lele, 2010 .

Honokiol Arrests Cell Cycle, Induces Apoptosis, and Potentiates the Cytotoxic Effect of Gemcitabine in Human Pancreatic Cancer Cells

S. Arora, A. Singh, S. Srivastava, 2011, PloS one.

Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in patients with pancreatic ductal adenocarcinoma.

S. Pai, A. Frankel, A. Singh, 2019, Journal of gastrointestinal oncology.

Dysregulation Of Metabolic Enzymes In Tumor And Stromal Cells: Role In Oncogenesis And Therapeutic Opportunities.

Mohammad Aslam Khan, A. Singh, S. Srivastava, 2020, Cancer letters.

The Journey of Mitochondrial Protein Import and the Roadmap to Follow

A. Singh, Seema Singh, Santanu Dasgupta, 2023, International journal of molecular sciences.

Drug-loaded exosomal preparations from different cell types exhibit distinctive loading capability, yield, and antitumor efficacies: a comparative analysis

Rajashekhar Kanchanapally, S. Chavva, A. Singh, 2019, International journal of nanomedicine.

Exosomes: Key Supporters of Tumor Metastasis

Aamir Ahmad, A. Singh, S. Srivastava, 2018 .

Cardiovascular Complications in Patients with Prostate Cancer: Potential Molecular Connections

A. Singh, Seema Singh, P. Pramanik, 2023, International journal of molecular sciences.

Gemcitabine treatment promotes immunosuppressive microenvironment in pancreatic tumors by supporting the infiltration, growth, and polarization of macrophages

A. Singh, S. Srivastava, K. Dugger, 2018, Scientific Reports.

MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways

S. Arora, A. Singh, S. Srivastava, 2015, British Journal of Cancer.

Unraveling the etiology of ovarian cancer racial disparity in the deep south: Is it nature or nurture?

A. Singh, J. Scalici, M. Finan, 2016, Gynecologic oncology.

MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming

A. Singh, S. Srivastava, H. Zubair, 2023, EMBO reports.

Revisiting the Clinical Importance of DPYD*9A (c.85T>C) Variant of Dihydropyrimidine Dehydrogenase (DPYD) Gene in Patients Treated with Fluoropyrimidine-Based Chemotherapy

W. Taylor, A. Singh, G. Patel, 2018, Journal of molecular biomarkers & diagnosis.

Size is an essential parameter in governing the UVB-protective efficacy of silver nanoparticles in human keratinocytes

S. Arora, S. Palanki, A. Singh, 2015, BMC Cancer.

Gemcitabine treatment promotes immunosuppressive microenvironment in pancreatic tumors by supporting the infiltration, growth, and polarization of macrophages

A. Singh, S. Srivastava, K. Dugger, 2018, Scientific Reports.

Resistin potentiates chemoresistance and stemness of breast cancer cells: Implications for racially disparate therapeutic outcomes.

A. Singh, S. Srivastava, H. Zubair, 2017, Cancer letters.

Looking at cancer health disparities without the colored lenses.

J. Pierce, A. Singh, S. Srivastava, 2019, Cancer health disparities.

Turning Adversity into Strength and Transferring It to the Uninitiated: The Tricks Cancer Cells Play to Survive Hypoxic Stress and Fight Chemotherapy

A. Singh, Shashi Anand, M. A. Khan, 2022, Cancers.

Clinicopathological significance of unraveling mitochondrial pathway alterations in non‐small‐cell lung cancer

Kate L. Hertweck, A. Singh, S. Dasgupta, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications

S. Arora, A. Singh, S. Srivastava, 2015, Oncotarget.

Racial disparities in prostate cancer: a molecular perspective.

Arun Bhardwaj, James E Carter, V. Prajapati, 2017, Frontiers in bioscience.

Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy

Sumit Arora, Ameya R. Kirtane, Jayanth Panyam, 2014, International journal of nanomedicine.

Resistin Induces LIN28A-Mediated Let-7a Repression in Breast Cancer Cells Leading to IL-6 and STAT3 Upregulation

Sanjeev Srivastava, A. Singh, H. Zubair, 2021, Cancers.

Hydroxytyrosol Induces Apoptosis and Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells

Aamir Ahmad, A. Singh, S. Srivastava, 2017, Nutrition and cancer.

Honokiol: a novel natural agent for cancer prevention and therapy.

G. Piazza, S. Arora, J. Panyam, 2012, Current molecular medicine.

SOCIOECONOMIC AND BEHAVIORAL FACTORS CONTRIBUTING TO RACIAL DISPARITIES IN PROSTATE CANCER

V. Prajapati, A. Singh, S. Srivastava, 2016 .

The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma

A. Singh, G. Patel, Omar Alkharabsheh, 2021, Oncotarget.

Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.

Lynette M. Smith, S. Batra, S. Johansson, 2008, Cancer letters.

CXCL12–CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy

A. Singh, S. Srivastava, A. Bhardwaj, 2010, British Journal of Cancer.

Resistin potentiates chemoresistance and stemness of breast cancer cells: Implications for racially disparate therapeutic outcomes.

A. Singh, S. Srivastava, H. Zubair, 2017, Cancer letters.

MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells.

J. Meza, S. Batra, A. Singh, 2008, Cancer research.