Xun Gu

发表

Statistical detection of differentially expressed genes based on RNA-seq: from biological to phylogenetic replicates

Xun Gu, X. Gu, 2016, Briefings Bioinform..

Model parameters of molecular evolution explain genomic correlations

Xun Gu, Wenda Tang, X. Gu, 2017, Briefings Bioinform..

Mathematical Modeling for Functional Divergence after Gene Duplication

Xun Gu, X. Gu, 2001, J. Comput. Biol..

Network motif comparison rationalizes Sec1/Munc18-SNARE regulation mechanism in exocytosis

Tian Xia, Julie A. Dickerson, Xun Gu, 2012, BMC Systems Biology.

Predicting binding sites of hydrolase-inhibitor complexes by combining several methods

Vasant Honavar, Andrzej Kloczkowski, Robert L. Jernigan, 2004, BMC Bioinformatics.

Evolutionary Analysis for Developmental Profiles of Gene Family Expression in Central Nervous System

Yufeng Wang, Xun Gu, X. Gu, 2002, Joint Conference on Information Sciences.

DIVERGE: phylogeny-based analysis for functional-structural divergence of a protein family

Xun Gu, Kent Vander Velden, X. Gu, 2002, Bioinform..

Modeling protein interaction network and mechanisms in exocytosis

Bo Su, Tian Xia, Wen Zhou, 2007, 2007 IEEE 7th International Symposium on BioInformatics and BioEngineering.

A Greedy Algorithm for Optimal Recombination

Xun Gu, Shiquan Wu, X. Gu, 2001, COCOON.

GeneContent: software for whole-genome phylogenetic analysis

Hongmei Zhang, Wei Huang, Xun Gu, 2005, Bioinform..

Gene Network: Model, Dynamics and Simulation

Xun Gu, Shiquan Wu, 2005, COCOON.

Multiple Genome Rearrangement by Reversals

Xun Gu, Shiquan Wu, Shiquan Wu, 2001, Pacific Symposium on Biocomputing.

Expression Pattern of Yeast Sporulation: A Case Study for Regulatory Changes after Yeast Genome Duplication

Wei Huang, Dan Nettleton, Xun Gu, 2002, JCIS.

Understanding tissue expression evolution: from expression phylogeny to phylogenetic network

Xun Gu, X. Gu, 2016, Briefings Bioinform..

SplitTester : software to identify domains responsible for functional divergence in protein family

Xiang Gao, Daniel F. Voytas, Xun Gu, 2005, BMC Bioinformatics.

Estimating the strength of expression conservation from high throughput RNA-seq data

Xun Gu, Hang Ruan, Jingwen Yang, 2019, Bioinform..

TSNAdb: A Database for Tumor-specific Neoantigens from Immunogenomics Data Analysis

Zhan Zhou, Binbin Zhou, Wenyi Zhao, 2018, Genom. Proteom. Bioinform..

Functional Divergence in TGF-b Signaling Pathway

Jianying Gu, Xun Gu, 2002, JCIS.

Evolutionary analysis of functional divergence in TGF- signaling pathway

Jianying Gu, Xun Gu, X. Gu, 2002, Inf. Sci..

Evolutionary and expression profiles of gene families crucial for central nervous system development

Yufeng Wang, Xun Gu, X. Gu, 2002, Inf. Sci..

A tool for comprehensive analysis of protein interaction networks

Jie Li, Tian Xia, Eve Syrkin Wurtele, 2007, BIOCOMP.

Algorithms for Multiple Genome Rearrangement by Signed Reversals

Xun Gu, Shiquan Wu, Shiquan Wu, 2001, Pacific Symposium on Biocomputing.

Toward a Realistic Model for Gene Network Evolution

Tian Xia, Wenhai Chen, Xun Gu, 2007, 2007 IEEE 7th International Symposium on BioInformatics and BioEngineering.

Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis

Xun Gu, Zhixi Su, Jingqi Zhou, 2017, Genom. Proteom. Bioinform..

A Site-specific Measure for Rate Difference After Gene Duplication or Speciation

Xun Gu, X. Gu, 2001 .

Differences in duplication age distributions between human GPCRs and their downstream genes from a network prospective

Ying Zheng, Xun Gu, Zhixi Su, 2009, BMC Genomics.

A bootstrap based analysis pipeline for efficient classification of phylogenetically related animal miRNAs

Xun Gu, X. Gu, Yong Huang, 2007, BMC Genomics.

Functional Divergence in Protein (Family) Sequence Evolution

Xun Gu, X. Gu, 2004, Genetica.

TSNAD: an integrated software for cancer somatic mutation and tumour-specific neoantigen detection

Xun Gu, Xingzheng Lyu, Jingcheng Wu, 2017, Royal Society Open Science.

Further statistical analysis for genome-wide expression evolution in primate brain/liver/fibroblast tissue

Xun Gu, X. Gu, J. Gu, 2003, Human Genomics.

A simple statistical method for estimating type-II (cluster-specific) functional divergence of protein sequences.

Xun Gu, X. Gu, 2006, Molecular biology and evolution.

How much expression divergence after yeast gene duplication could be explained by regulatory motif evolution?

Xun Gu, Zhongqi Zhang, X. Gu, 2004, Trends in genetics : TIG.

Characterization of paralogous protein families in rice

Kan Nobuta, Blake C Meyers, Wei Zhu, 2008, BMC Plant Biology.

Identification of copy number variation hotspots in human populations.

Li Jin, Wenqing Fu, Xun Gu, 2010, American journal of human genetics.

Novel PAX6 binding sites in the human genome and the role of repetitive elements in the evolution of gene regulation.

Xun Gu, X. Gu, W. Yung, 2002, Genome research.

Age distribution of human gene families shows significant roles of both large- and small-scale duplications in vertebrate evolution

Xun Gu, Yufeng Wang, X. Gu, 2002, Nature Genetics.

Directional mutational pressure affects the amino acid composition and hydrophobicity of proteins in bacteria

Xun Gu, D. Hewett‐Emmett, X. Gu, 2004, Genetica.

Comparative analyses reveal distinct sets of lineage-specific genes within Arabidopsis thaliana

Xun Gu, C Robin Buell, Shin-Han Shiu, 2010, BMC Evolutionary Biology.

Functional divergence in protein (family) sequence evolution.

Xun Gu, X. Gu, 2003 .

Statistical models for studying DNA sequence evolution

Xun Gu, X. Gu, Wen-Hsiung Li, 1995 .

Functional divergence after gene duplication and sequence-structure relationship: a case study of G-protein alpha subunits.

Ying Zheng, Xun Gu, X. Gu, 2007, Journal of experimental zoology. Part B, Molecular and developmental evolution.

Statistical Applications in Genetics and Molecular Biology Maximum Likelihood for Genome Phylogeny on Gene Content

Xun Gu, Hongmei Zhang, X. Gu, 2011 .

Genome phylogenetic analysis based on extended gene contents.

Xun Gu, X. Gu, Hongmei Zhang, 2004, Molecular biology and evolution.

The size distribution of insertions and deletions in human and rodent pseudogenes suggests the logarithmic gap penalty for sequence alignment

Xun Gu, X. Gu, Wen-Hsiung Li, 1995, Journal of Molecular Evolution.

Predicting functional divergence in protein evolution by site-specific rate shifts.

Xun Gu, Steven A Benner, Eric A Gaucher, 2002, Trends in biochemical sciences.

An update of DIVERGE software for functional divergence analysis of protein family.

Wei Huang, Xun Gu, Zebulun Arendsee, 2013, Molecular biology and evolution.

A Simple Statistical Method for Estimating Type-II ( Cluster-Specific ) Functional Divergence of Protein Sequences

Xun Gu, X. Gu, 2006 .

An evolutionary model for the origin of modularity in a complex gene network.

Xun Gu, X. Gu, 2009, Journal of experimental zoology. Part B, Molecular and developmental evolution.

Sex Differences in Mutation Rate in Higher Primates Estimated from AMG Intron Sequences

Wei Huang, Xun Gu, D. Hewett‐Emmett, 1997, Journal of Molecular Evolution.